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Cheap flights from North Carolina to Santa Fe from $264

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Santa Fe departing on 12/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from North Carolina to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:46 am - 9:41 amTYS-SAF
5h 55m1 stop
American Airlines Logo
10:08 am - 5:30 pmSAF-TYS
5h 22m1 stop
$318American Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
4:17 pm - 8:01 pmAVL-SAF
5h 44m1 stop
American Airlines Logo
6:26 pm - 10:12 amSAF-AVL
13h 46m2 stops
$324American Airlines
Find Deal
Tue, May 5 - Tue, May 19
United Airlines Logo
3:05 pm - 9:59 pmRDU-SAF
8h 54m2 stops
United Airlines Logo
7:00 am - 3:06 pmSAF-RDU
6h 06m1 stop
$325United Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 7
American Airlines Logo
4:29 pm - 8:50 pmTYS-SAF
6h 21m1 stop
American Airlines Logo
10:08 am - 11:59 pmSAF-TYS
11h 51m2 stops
$328American Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
6:30 am - 12:22 pmGSO-SAF
7h 52m1 stop
American Airlines Logo
4:12 pm - 11:39 pmSAF-GSO
5h 27m1 stop
$344American Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
8:00 am - 12:37 pmRDU-SAF
6h 37m1 stop
United Airlines Logo
1:20 pm - 10:45 pmSAF-RDU
7h 25m1 stop
$354United Airlines
Find Deal
Tue, Dec 2 - Thu, Dec 11
American Airlines Logo
5:14 am - 3:02 pmGSO-SAF
11h 48m2 stops
American Airlines Logo
4:12 pm - 11:39 pmSAF-GSO
5h 27m1 stop
$354American Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
10:45 am - 5:57 pmCLT-SAF
9h 12m1 stop
American Airlines Logo
5:05 pm - 12:40 amSAF-CLT
5h 35m1 stop
$357American Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
5:14 am - 3:02 pmGSO-SAF
11h 48m2 stops
American Airlines Logo
10:08 am - 10:29 pmSAF-GSO
10h 21m2 stops
$359American Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
8:00 am - 12:37 pmRDU-SAF
6h 37m1 stop
United Airlines Logo
1:20 pm - 11:44 pmSAF-RDU
8h 24m2 stops
$364United Airlines
Find Deal
Tue, Dec 2 - Thu, Dec 11

American Airlines flights from North Carolina to Santa Fe

Our best American Airlines deals on North Carolina to Santa Fe flight tickets
American Airlines
Feb 21
TYS5:46 amKnoxville McGhee Tyson
5h 55m
1 stop
SAF9:41 amSanta Fe
Feb 25
SAF10:08 amSanta Fe
5h 22m
1 stop
TYS5:30 pmKnoxville McGhee Tyson
$318
Find similar
American Airlines
May 5
AVL4:17 pmAsheville Regional
5h 44m
1 stop
SAF8:01 pmSanta Fe
May 19
SAF6:26 pmSanta Fe
13h 46m
2 stops
AVL10:12 amAsheville Regional
$324
Find similar
American Airlines
Feb 21
TYS4:29 pmKnoxville McGhee Tyson
6h 21m
1 stop
SAF8:50 pmSanta Fe
Feb 25
SAF10:08 amSanta Fe
11h 51m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$328
Find similar

United Airlines flights from North Carolina to Santa Fe

Our best United Airlines deals on North Carolina to Santa Fe flight tickets
United Airlines
Dec 5
RDU3:05 pmRaleigh-Durham
8h 54m
2 stops
SAF9:59 pmSanta Fe
Dec 7
SAF7:00 amSanta Fe
6h 06m
1 stop
RDU3:06 pmRaleigh-Durham
$325
Find similar
United Airlines
Dec 2
RDU8:00 amRaleigh-Durham
6h 37m
1 stop
SAF12:37 pmSanta Fe
Dec 11
SAF1:20 pmSanta Fe
7h 25m
1 stop
RDU10:45 pmRaleigh-Durham
$354
Find similar
United Airlines
Dec 2
RDU8:00 amRaleigh-Durham
6h 37m
1 stop
SAF12:37 pmSanta Fe
Dec 11
SAF1:20 pmSanta Fe
8h 24m
2 stops
RDU11:44 pmRaleigh-Durham
$364
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 9, 2025.
Use the filters below to find and compare flights from North Carolina to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

Sat 2/21

5:46 am-9:41 am

1 stop5h 55m

Santa Fe

Wed 2/25

10:08 am-5:30 pm

1 stop5h 22m

$318

AshevilleSanta Fe

AVL - SAF

AVLSAF

Asheville Regional

Tue 5/5

4:17 pm-8:01 pm

1 stop5h 44m

Santa Fe

Tue 5/19

6:26 pm-10:12 am

2 stops13h 46m

$324

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Fri 12/5

3:05 pm-9:59 pm

2 stops8h 54m

Santa Fe

Sun 12/7

7:00 am-3:06 pm

1 stop6h 06m

$325

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

Sat 2/21

4:29 pm-8:50 pm

1 stop6h 21m

Santa Fe

Wed 2/25

10:08 am-11:59 pm

2 stops11h 51m

$328

GreensboroSanta Fe

GSO - SAF

GSOSAF

Greensboro/H. Point

Sat 2/21

6:30 am-12:22 pm

1 stop7h 52m

Santa Fe

Wed 2/25

4:12 pm-11:39 pm

1 stop5h 27m

$344

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 12/2

8:00 am-12:37 pm

1 stop6h 37m

Santa Fe

Thu 12/11

1:20 pm-10:45 pm

1 stop7h 25m

$354

GreensboroSanta Fe

GSO - SAF

GSOSAF

Greensboro/H. Point

Sat 2/21

5:14 am-3:02 pm

2 stops11h 48m

Santa Fe

Wed 2/25

4:12 pm-11:39 pm

1 stop5h 27m

$354

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Thu 1/15

10:45 am-5:57 pm

1 stop9h 12m

Santa Fe

Sun 1/18

5:05 pm-12:40 am

1 stop5h 35m

$357

GreensboroSanta Fe

GSO - SAF

GSOSAF

Greensboro/H. Point

Sat 2/21

5:14 am-3:02 pm

2 stops11h 48m

Santa Fe

Wed 2/25

10:08 am-10:29 pm

2 stops10h 21m

$359

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Tue 12/2

8:00 am-12:37 pm

1 stop6h 37m

Santa Fe

Thu 12/11

1:20 pm-11:44 pm

2 stops8h 24m

$364

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from North Carolina to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Fe?

The month of October is, on average, the cheapest month to fly to Santa Fe from North Carolina, with most prices found around $349. If you’re not able to fly to Santa Fe in October, then January is your next best option. Flight prices from North Carolina to Santa Fe during January average around $373.

What is the cheapest day to depart on your flight to Santa Fe?

According to our data, Tuesday is the cheapest day to fly to Santa Fe from North Carolina. The lowest ticket price found for a Tuesday departure recently was $400. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santa Fe on Thursday is $676.

What is the cheapest time of day to depart on your flight to Santa Fe?

The cheapest time of day to fly to Santa Fe is in the afternoon when flights can be purchased for as low as $461. Try not to purchase tickets in the morning because they tend to be around $507. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap North Carolina to Santa Fe flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Santa Fe

Direct flights

None
There are no direct flights from North Carolina to Santa Fe. There are no popular flight routes from North Carolina to Santa Fe.
Search flight deals

  • When did momondo last update prices for flights from North Carolina to Santa Fe Airport?

    Prices for flights from North Carolina to Santa Fe Airport refresh daily.

  • How many operators does momondo search for flights from North Carolina to Santa Fe Airport?

  • How old do you have to be to fly from North Carolina to Santa Fe Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from North Carolina to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The travel and health documents you'll need for your trip to Santa Fe Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Fe Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from North Carolina to Santa Fe

Compare and see reviews for airlines that fly from North Carolina to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $263Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
United AirlinesPriceFrom $284Free CancellationRating
7.4
9,010 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Santa Fe?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from North Carolina to Santa Fe. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from North Carolina to Santa Fe with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Fe from North Carolina with this policy.

How can momondo help me find flights from North Carolina to Santa Fe?

Once you have performed a search for North Carolina to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from North Carolina to Santa Fe right now. Can momondo alert me if prices change?

If you are not ready to book a flight from North Carolina to Santa Fe now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Fe and let you know when they change.

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