What is the cheapest airline that flies from Myrtle Beach Intl to Des Moines?

American Airlines and Delta are the most popular carriers operating from Myrtle Beach Intl to Des Moines

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Des Moines Airport?

Prices for flights from Myrtle Beach Intl Airport to Des Moines Airport are updated daily.

How old do you have to be to fly from Myrtle Beach Intl Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$148 Cheap Flights from Myrtle Beach to Des Moines in 2025/26

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Find the cheapest flights from Myrtle Beach to Des Moines

Round-trip

One-way

Cheap round-trip flights

10:17 am - 5:02 pmMYR-DSM

7h 45m1 stop

5:04 pm - 10:36 pmDSM-MYR

4h 32m1 stop

$251American Airlines

Find Deal

mié., oct. 29 - mar., nov. 4

4:47 pm - 11:16 pmMYR-DSM

7h 29m1 stop

5:00 am - 2:46 pmDSM-MYR

8h 46m2 stops

$256American Airlines

Find Deal

mié., oct. 29 - mar., nov. 4

1:20 pm - 9:50 pmMYR-DSM

9h 30m2 stops

6:15 am - 5:25 pmDSM-MYR

10h 10m2 stops

$261Southwest

Find Deal

mié., oct. 29 - mar., nov. 4

7:43 pm - 8:44 amMYR-DSM

14h 01m1 stop

8:30 am - 12:48 pmDSM-MYR

27h 18m1 stop

$280Multiple Airlines

Find Deal

jue., oct. 23 - lun., oct. 27

5:21 am - 10:51 amMYR-DSM

6h 30m1 stop

3:18 pm - 8:49 pmDSM-MYR

4h 31m1 stop

$285American Airlines

Find Deal

lun., oct. 27 - lun., nov. 3

10:01 am - 5:37 pmMYR-DSM

8h 36m2 stops

6:00 am - 2:10 pmDSM-MYR

7h 10m1 stop

$290American Airlines

Find Deal

jue., oct. 23 - lun., oct. 27

6:15 am - 2:55 pmMYR-DSM

9h 40m2 stops

8:40 am - 10:08 amDSM-MYR

24h 28m1 stop

$303Multiple Airlines

Find Deal

vie., nov. 7 - lun., nov. 10

12:40 pm - 11:35 pmMYR-DSM

11h 55m2 stops

8:00 am - 9:30 pmDSM-MYR

12h 30m2 stops

$335Southwest

Find Deal

vie., nov. 7 - lun., nov. 10

2:05 pm - 11:44 pmMYR-DSM

10h 39m2 stops

3:15 pm - 2:57 pmDSM-MYR

22h 42m3 stops

$606United Airlines

Find Deal

mié., oct. 29 - mar., nov. 4

3:53 pm - 4:13 pmMYR-DSM

25h 20m2 stops

3:15 pm - 2:57 pmDSM-MYR

22h 42m3 stops

$625United Airlines

Find Deal

vie., nov. 7 - lun., nov. 10

American Airlines flights from Myrtle Beach to Des Moines

Our best American Airlines deals on Myrtle Beach to Des Moines flight tickets

American Airlines

Oct 29

MYR10:17 amMyrtle Beach Intl

7h 45m

1 stop

DSM5:02 pmDes Moines

Nov 4

DSM5:04 pmDes Moines

4h 32m

1 stop

MYR10:36 pmMyrtle Beach Intl

$251

Find similar

American Airlines

Oct 29

MYR4:47 pmMyrtle Beach Intl

7h 29m

1 stop

DSM11:16 pmDes Moines

Nov 4

DSM5:00 amDes Moines

8h 46m

2 stops

MYR2:46 pmMyrtle Beach Intl

$256

Find similar

American Airlines

Oct 27

MYR5:21 amMyrtle Beach Intl

6h 30m

1 stop

DSM10:51 amDes Moines

Nov 3

DSM3:18 pmDes Moines

4h 31m

1 stop

MYR8:49 pmMyrtle Beach Intl

$285

Find similar

Delta flights from Myrtle Beach to Des Moines

Our best Delta deals on Myrtle Beach to Des Moines flight tickets

Delta

Oct 7

MYR12:20 pmMyrtle Beach Intl

8h 00m

1 stop

DSM7:20 pmDes Moines

Oct 18

DSM5:15 pmDes Moines

5h 44m

1 stop

MYR11:59 pmMyrtle Beach Intl

$548

Find similar

Delta

Oct 7

MYR12:20 pmMyrtle Beach Intl

8h 00m

1 stop

DSM7:20 pmDes Moines

Oct 18

DSM12:30 pmDes Moines

10h 29m

2 stops

MYR11:59 pmMyrtle Beach Intl

$553

Find similar

Delta

Oct 7

MYR11:29 amMyrtle Beach Intl

12h 01m

2 stops

DSM10:30 pmDes Moines

Oct 18

DSM12:30 pmDes Moines

10h 29m

2 stops

MYR11:59 pmMyrtle Beach Intl

$558

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mié. 10/29

10:17 am-5:02 pm

1 stop7h 45m

Des Moines

mar. 11/4

5:04 pm-10:36 pm

1 stop4h 32m

$251

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mié. 10/29

4:47 pm-11:16 pm

1 stop7h 29m

Des Moines

mar. 11/4

5:00 am-2:46 pm

2 stops8h 46m

$256

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mié. 10/29

1:20 pm-9:50 pm

2 stops9h 30m

Des Moines

mar. 11/4

6:15 am-5:25 pm

2 stops10h 10m

$261

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

jue. 10/23

7:43 pm-8:44 am

1 stop14h 01m

Des Moines

lun. 10/27

8:30 am-12:48 pm

1 stop27h 18m

$280

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

lun. 10/27

5:21 am-10:51 am

1 stop6h 30m

Des Moines

lun. 11/3

3:18 pm-8:49 pm

1 stop4h 31m

$285

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

jue. 10/23

10:01 am-5:37 pm

2 stops8h 36m

Des Moines

lun. 10/27

6:00 am-2:10 pm

1 stop7h 10m

$290

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

vie. 11/7

6:15 am-2:55 pm

2 stops9h 40m

Des Moines

lun. 11/10

8:40 am-10:08 am

1 stop24h 28m

$303

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

vie. 11/7

12:40 pm-11:35 pm

2 stops11h 55m

Des Moines

lun. 11/10

8:00 am-9:30 pm

2 stops12h 30m

$335

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mié. 10/29

2:05 pm-11:44 pm

2 stops10h 39m

Des Moines

mar. 11/4

3:15 pm-2:57 pm

3 stops22h 42m

$606

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

vie. 11/7

3:53 pm-4:13 pm

2 stops25h 20m

Des Moines

lun. 11/10

3:15 pm-2:57 pm

3 stops22h 42m

$625

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Myrtle Beach to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $258. Flights from Myrtle Beach to Des Moines on a Thursday will generally be more expensive and average around $306. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Myrtle Beach to Des Moines in the morning for as low as $296. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $306. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Myrtle Beach to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Myrtle Beach to Des Moines (MYR to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Des Moines

Direct flights	None

There are no direct flights from Myrtle Beach to Des Moines. There are no popular flight routes from Myrtle Beach to Des Moines.

Search flight deals

How far is Myrtle Beach Intl to Des Moines by plane?
The distance between Myrtle Beach Intl and Des Moines is about 970.9 mi. Flights usually cover this in 4h 16m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Myrtle Beach Intl Airport to Des Moines Airport?
Prices for flights from Myrtle Beach Intl Airport to Des Moines Airport are updated daily.
How old do you have to be to fly from Myrtle Beach Intl Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Pella

Newton

Johnston

Boone

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Des Moines?

It is quick and easy to find Myrtle Beach to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Myrtle Beach to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Des Moines?

Once all potential Myrtle Beach to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.