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Cheap flights from Moline to Florence from $396

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Moline to Florence departing on 1/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:31 am - 5:09 pmMLI-FLO
8h 38m2 stops
American Airlines Logo
5:36 pm - 9:33 pmFLO-MLI
4h 57m1 stop
$396American Airlines
Find Deal
Sat, Jan 17 - Tue, Jan 20
American Airlines Logo
4:30 pm - 11:38 pmMLI-FLO
6h 08m1 stop
American Airlines Logo
11:09 am - 3:48 pmFLO-MLI
5h 39m1 stop
$473American Airlines
Find Deal
Wed, Mar 11 - Sat, Mar 14
American Airlines Logo
11:28 am - 11:11 pmMLI-FLO
10h 43m2 stops
American Airlines Logo
6:15 am - 3:27 pmFLO-MLI
10h 12m2 stops
$477American Airlines
Find Deal
Sat, Jan 17 - Tue, Jan 20
American Airlines Logo
4:30 pm - 11:38 pmMLI-FLO
6h 08m1 stop
American Airlines Logo
2:30 pm - 9:31 pmFLO-MLI
8h 01m2 stops
$478American Airlines
Find Deal
Wed, Mar 11 - Sat, Mar 14
American Airlines Logo
1:11 pm - 11:38 pmMLI-FLO
9h 27m2 stops
American Airlines Logo
11:09 am - 5:35 pmFLO-MLI
7h 26m2 stops
$535American Airlines
Find Deal
Wed, Mar 11 - Sat, Mar 14
American Airlines Logo
6:15 am - 5:09 pmMLI-FLO
9h 54m1 stop
American Airlines Logo
5:36 pm - 9:33 pmFLO-MLI
4h 57m1 stop
$709American Airlines
Find Deal
Sat, Jan 17 - Tue, Jan 20

American Airlines flights from Moline to Florence, South Carolina

Our best American Airlines deals on Moline to Florence, South Carolina flight tickets
American Airlines
Jan 17
MLI7:31 amMoline Quad-City
8h 38m
2 stops
FLO5:09 pmFlorence
Jan 20
FLO5:36 pmFlorence
4h 57m
1 stop
MLI9:33 pmMoline Quad-City
$396
Find similar
American Airlines
Mar 11
MLI4:30 pmMoline Quad-City
6h 08m
1 stop
FLO11:38 pmFlorence
Mar 14
FLO11:09 amFlorence
5h 39m
1 stop
MLI3:48 pmMoline Quad-City
$473
Find similar
American Airlines
Jan 17
MLI11:28 amMoline Quad-City
10h 43m
2 stops
FLO11:11 pmFlorence
Jan 20
FLO6:15 amFlorence
10h 12m
2 stops
MLI3:27 pmMoline Quad-City
$477
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Moline to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Moline to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 1/17

7:31 am-5:09 pm

2 stops8h 38m

Florence

Tue 1/20

5:36 pm-9:33 pm

1 stop4h 57m

$396

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Wed 3/11

4:30 pm-11:38 pm

1 stop6h 08m

Florence

Sat 3/14

11:09 am-3:48 pm

1 stop5h 39m

$473

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 1/17

11:28 am-11:11 pm

2 stops10h 43m

Florence

Tue 1/20

6:15 am-3:27 pm

2 stops10h 12m

$477

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Wed 3/11

4:30 pm-11:38 pm

1 stop6h 08m

Florence

Sat 3/14

2:30 pm-9:31 pm

2 stops8h 01m

$478

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Wed 3/11

1:11 pm-11:38 pm

2 stops9h 27m

Florence

Sat 3/14

11:09 am-5:35 pm

2 stops7h 26m

$535

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 1/17

6:15 am-5:09 pm

1 stop9h 54m

Florence

Tue 1/20

5:36 pm-9:33 pm

1 stop4h 57m

$709

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Moline to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florence, South Carolina from Moline according to our data. American Airlines is the first choice among our users, with 83% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 3 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Moline to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Moline to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Moline to Florence, South Carolina (MLI to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Moline to Florence, South Carolina

Direct flights

None
There are no direct flights from Moline to Florence, South Carolina. There are no popular flight routes from Moline to Florence, South Carolina.
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  • How far is Moline Quad-City to Florence by plane?

    Moline Quad-City and Florence are 772.5 mi apart from one another. 6h 08m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Moline Quad-City Airport to Florence Airport?

    Prices for flights from Moline Quad-City Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Moline Quad-City Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Moline Quad-City Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Moline to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Moline.

Can I find flights from Moline to Florence with flexible booking policies on momondo?

Flights from Moline to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Moline to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Moline.

I’m not ready to book a flight from Moline to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Moline to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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