Cheap flights from Missouri to South America from $130
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to South America departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from Missouri to South America
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Delta flights from Missouri to South America
Our best Delta deals on Missouri to South America flight tickets
Spirit Airlines flights from Missouri to South America
Our best Spirit Airlines deals on Missouri to South America flight tickets
How to get the cheapest flight ticket from Missouri to South America
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to South America?
In general, September is the cheapest month to fly from Missouri to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $681. If you aren’t able to travel during the month of September, then book flights to South America from Missouri during February instead. Flights to South America in February, while not as cheap as those in September, still average around $746.
What is the cheapest day to depart on your flight to South America?
The cheapest day to depart from Missouri to South America is on a Wednesday when prices can be found for as low as $741. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Missouri to South America for around $967.
What is the cheapest time of day to depart on your flight to South America?
Our data shows that the cheapest Missouri to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $785. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $831 on average. Flights to South America from Missouri at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.
How far in advance should I book a flight to South America?
You are more likely to see cheaper flights to South America from Missouri when booking 24 weeks ahead of your departure date. In general, you can expect to find flights to South America for around $802 when searching 24 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Missouri for as low as $676 on momondo.
What is the cheapest airline that flies from Missouri to South America?
Spirit Airlines, Copa Airlines, and American Airlines are the most popular carriers operating from Missouri to South America
What airlines fly to South America?
Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Missouri according to our data. Delta is the first choice among our users, with 38% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 5 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.
Cheap Missouri to South America flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Missouri to South America
When did momondo last update prices for flights from Missouri to South America?
Prices for flights from Missouri to South America are updated daily.
How many operators does momondo search for flights from Missouri to South America?
There are 5 operators available for flights from Missouri to South America as of May 2025.
How old do you have to be to fly from Missouri to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
Best airlines flying from Missouri to South America
Compare and see reviews for airlines that fly from Missouri to South America with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $271 | Free Cancellation | Rating 6.3 7,966 reviews | |||
| PriceFrom $389 | Free Cancellation | Rating 8.0 7,940 reviews | |||
| PriceFrom $399 | Free Cancellation | Rating 7.4 8,701 reviews | |||
| PriceFrom $409 | Free Cancellation | Rating 7.5 1,766 reviews | |||
| PriceFrom $449 | Free Cancellation | Rating 7.2 10,000 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from Missouri to South America?
Finding the right flight to South America from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.
Can I find flights from Missouri to South America with flexible booking policies on momondo?
Yes. momondo allows you to filter the results for Missouri to South America flights to just show those with flexible booking policies.
How can momondo help me find flights from Missouri to South America?
Once all potential Missouri to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.
I’m not ready to book a flight from Missouri to South America right now. Can momondo alert me if prices change?
If you are not ready to book a flight from Missouri to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.