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Cheap flights from Missouri to Lafayette from $249

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Lafayette departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Lafayette

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:54 pm - 9:03 pmSTL-LFT
5h 09m1 stop
American Airlines Logo
6:33 pm - 10:59 pmLFT-STL
4h 26m1 stop
$249American Airlines
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Fri, Jan 23 - Mon, Jan 26
American Airlines Logo
11:05 am - 9:03 pmSTL-LFT
9h 58m2 stops
American Airlines Logo
10:30 am - 4:14 pmLFT-STL
5h 44m1 stop
$254American Airlines
Find Deal
Fri, Jan 23 - Mon, Jan 26
Delta Logo
10:13 am - 2:29 pmSTL-LFT
4h 16m1 stop
Delta Logo
3:09 pm - 7:24 pmLFT-STL
4h 15m1 stop
$264Delta
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Wed, Feb 18 - Sat, Feb 21
Delta Logo
5:04 pm - 10:15 pmSTL-LFT
5h 11m1 stop
Delta Logo
5:15 pm - 11:39 pmLFT-STL
6h 24m1 stop
$294Delta
Find Deal
Wed, Feb 4 - Mon, Feb 9
American Airlines Logo
1:15 pm - 9:20 pmSGF-LFT
8h 05m1 stop
American Airlines Logo
7:04 am - 5:04 pmLFT-SGF
10h 00m2 stops
$294American Airlines
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Wed, Feb 18 - Sat, Feb 21
American Airlines Logo
10:22 am - 9:20 pmSGF-LFT
10h 58m2 stops
American Airlines Logo
7:04 am - 5:04 pmLFT-SGF
10h 00m2 stops
$299American Airlines
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Wed, Feb 18 - Sat, Feb 21
United Airlines Logo
7:00 am - 7:26 pmSTL-LFT
12h 26m2 stops
United Airlines Logo
9:50 am - 11:59 pmLFT-STL
14h 09m2 stops
$329United Airlines
Find Deal
Fri, Jan 23 - Mon, Jan 26
United Airlines Logo
6:15 am - 1:16 pmSTL-LFT
7h 01m1 stop
United Airlines Logo
2:00 pm - 11:42 pmLFT-STL
9h 42m2 stops
$339United Airlines
Find Deal
Fri, Nov 28 - Tue, Dec 9
United Airlines Logo
6:15 am - 11:15 amSTL-LFT
5h 00m1 stop
United Airlines Logo
9:50 am - 4:04 pmLFT-STL
6h 14m1 stop
$343United Airlines
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Fri, Nov 28 - Tue, Dec 9
Delta Logo
3:41 pm - 10:17 pmSTL-LFT
6h 36m1 stop
Delta Logo
5:29 pm - 9:43 pmLFT-STL
4h 14m1 stop
$599Delta
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Tue, Dec 23 - Sat, Dec 27

American Airlines flights from Missouri to Lafayette

Our best American Airlines deals on Missouri to Lafayette flight tickets
American Airlines
Jan 23
STL3:54 pmLambert-St Louis
5h 09m
1 stop
LFT9:03 pmLafayette Regional
Jan 26
LFT6:33 pmLafayette Regional
4h 26m
1 stop
STL10:59 pmLambert-St Louis
$249
Find similar
American Airlines
Jan 23
STL11:05 amLambert-St Louis
9h 58m
2 stops
LFT9:03 pmLafayette Regional
Jan 26
LFT10:30 amLafayette Regional
5h 44m
1 stop
STL4:14 pmLambert-St Louis
$254
Find similar
American Airlines
Feb 18
SGF1:15 pmSpringfield-Branson
8h 05m
1 stop
LFT9:20 pmLafayette Regional
Feb 21
LFT7:04 amLafayette Regional
10h 00m
2 stops
SGF5:04 pmSpringfield-Branson
$294
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Delta flights from Missouri to Lafayette

Our best Delta deals on Missouri to Lafayette flight tickets
Delta
Feb 18
STL10:13 amLambert-St Louis
4h 16m
1 stop
LFT2:29 pmLafayette Regional
Feb 21
LFT3:09 pmLafayette Regional
4h 15m
1 stop
STL7:24 pmLambert-St Louis
$264
Find similar
Delta
Feb 4
STL5:04 pmLambert-St Louis
5h 11m
1 stop
LFT10:15 pmLafayette Regional
Feb 9
LFT5:15 pmLafayette Regional
6h 24m
1 stop
STL11:39 pmLambert-St Louis
$294
Find similar
Delta
Nov 7
STL3:59 pmLambert-St Louis
6h 32m
1 stop
LFT10:31 pmLafayette Regional
Nov 10
LFT5:25 pmLafayette Regional
6h 19m
1 stop
STL11:44 pmLambert-St Louis
$369
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Lafayette that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Lafayette that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 1/23

3:54 pm-9:03 pm

1 stop5h 09m

Lafayette Regional

Mon 1/26

6:33 pm-10:59 pm

1 stop4h 26m

$249

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 1/23

11:05 am-9:03 pm

2 stops9h 58m

Lafayette Regional

Mon 1/26

10:30 am-4:14 pm

1 stop5h 44m

$254

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Wed 2/18

10:13 am-2:29 pm

1 stop4h 16m

Lafayette Regional

Sat 2/21

3:09 pm-7:24 pm

1 stop4h 15m

$264

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Wed 2/4

5:04 pm-10:15 pm

1 stop5h 11m

Lafayette Regional

Mon 2/9

5:15 pm-11:39 pm

1 stop6h 24m

$294

SpringfieldLafayette

SGF - LFT

SGFLFT

Springfield-Branson

Wed 2/18

1:15 pm-9:20 pm

1 stop8h 05m

Lafayette Regional

Sat 2/21

7:04 am-5:04 pm

2 stops10h 00m

$294

SpringfieldLafayette

SGF - LFT

SGFLFT

Springfield-Branson

Wed 2/18

10:22 am-9:20 pm

2 stops10h 58m

Lafayette Regional

Sat 2/21

7:04 am-5:04 pm

2 stops10h 00m

$299

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 1/23

7:00 am-7:26 pm

2 stops12h 26m

Lafayette Regional

Mon 1/26

9:50 am-11:59 pm

2 stops14h 09m

$329

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 11/28

6:15 am-1:16 pm

1 stop7h 01m

Lafayette Regional

Tue 12/9

2:00 pm-11:42 pm

2 stops9h 42m

$339

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 11/28

6:15 am-11:15 am

1 stop5h 00m

Lafayette Regional

Tue 12/9

9:50 am-4:04 pm

1 stop6h 14m

$343

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Tue 12/23

3:41 pm-10:17 pm

1 stop6h 36m

Lafayette Regional

Sat 12/27

5:29 pm-9:43 pm

1 stop4h 14m

$599

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Lafayette from

How to get the cheapest flight ticket from Missouri to Lafayette

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Lafayette?

If you’re not able to fly to Lafayette in February, then January is your next best option. Flight prices from Missouri to Lafayette during January average around $278.

What is the cheapest day to depart on your flight to Lafayette?

The cheapest day to depart from Missouri to Lafayette is on a Tuesday. Travelers who choose to depart for Lafayette on a Tuesday will often find tickets for as low as $270. The most expensive day to fly to Lafayette is Friday, with ticket prices averaging around $452.

What is the cheapest time of day to depart on your flight to Lafayette?

In the morning is the cheapest time of day to fly from Missouri to Lafayette when you can find flight prices for as low as $298. Flying to Lafayette in the morning is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $488 on average. Flights to Lafayette from Missouri in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Cheap Missouri to Lafayette flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Lafayette

Direct flights

None
There are no direct flights from Missouri to Lafayette. There are no popular flight routes from Missouri to Lafayette.
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  • When did momondo last update prices for flights from Missouri to Lafayette Regional Airport?

    Prices for flights from Missouri to Lafayette Regional Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Lafayette Regional Airport?

  • How old do you have to be to fly from Missouri to Lafayette Regional Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Lafayette Regional Airport.

  • What documentation or ID do you need to fly to Lafayette Regional Airport?

    The required travel and health documents for your Lafayette Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lafayette Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Lafayette

Compare and see reviews for airlines that fly from Missouri to Lafayette with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $198Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $253Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights

Traveling to a place near Lafayette?

Book flights to Lafayette if you plan to visit one of these locations
Opelousas

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Lafayette?

Finding the right flight to Lafayette from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Lafayette quick and easy, saving you time and money.

Can I find flights from Missouri to Lafayette with flexible booking policies on momondo?

All flight searches from Missouri to Lafayette on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to Lafayette?

Once you have performed a search for Missouri to Lafayette flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Missouri to Lafayette right now. Can momondo alert me if prices change?

Price alerts on flights to Lafayette from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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