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Cheap flights from Missouri to La Crosse from $418

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to La Crosse departing on 9/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to La Crosse

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:13 am - 11:22 amMCI  Kansas City-LSE La Crosse
6h 09m1 stop Chicago O'Hare Intl
American Airlines Logo
5:22 pm - 12:23 amLSE  La Crosse-MCI Kansas City
7h 01m1 stop Chicago O'Hare Intl
$418American Airlines
Tue, Sep 15 - Wed, Sep 23
American Airlines Logo
5:00 am - 12:22 amMCI  Kansas City-LSE La Crosse
19h 22m1 stop Chicago O'Hare Intl
American Airlines Logo
5:20 pm - 8:40 amLSE  La Crosse-MCI Kansas City
15h 20m1 stop Chicago O'Hare Intl
$448American Airlines
Thu, Sep 3 - Mon, Sep 7
American Airlines Logo
5:13 am - 12:20 amMCI  Kansas City-LSE La Crosse
19h 07m1 stop Chicago O'Hare Intl
American Airlines Logo
5:22 pm - 8:38 amLSE  La Crosse-MCI Kansas City
15h 16m1 stop Chicago O'Hare Intl
$459American Airlines
Fri, Sep 18 - Sun, Sep 20
American Airlines Logo
10:38 am - 12:17 amSGF  Springfield-Branson-LSE La Crosse
13h 39m1 stop Chicago O'Hare Intl
American Airlines Logo
6:01 am - 4:52 pmLSE  La Crosse-SGF Springfield-Branson
10h 51m1 stop Chicago O'Hare Intl
$486American Airlines
Fri, Nov 13 - Mon, Nov 16
American Airlines Logo
6:44 am - 4:52 pmMCI  Kansas City-LSE La Crosse
10h 08m2 stops Dallas/Fort Worth Chicago O'Hare Intl
American Airlines Logo
5:22 pm - 12:23 amLSE  La Crosse-MCI Kansas City
7h 01m1 stop Chicago O'Hare Intl
$501American Airlines
Tue, Sep 15 - Wed, Sep 23
American Airlines Logo
8:04 pm - 12:22 amSGF  Springfield-Branson-LSE La Crosse
4h 18m1 stop Chicago O'Hare Intl
American Airlines Logo
6:04 am - 10:04 amLSE  La Crosse-SGF Springfield-Branson
4h 00m1 stop Chicago O'Hare Intl
$508American Airlines
Tue, Aug 25 - Sat, Aug 29
American Airlines Logo
5:00 am - 11:31 amMCI  Kansas City-LSE La Crosse
6h 31m1 stop Chicago O'Hare Intl
American Airlines Logo
12:19 pm - 7:02 pmLSE  La Crosse-MCI Kansas City
6h 43m1 stop Chicago O'Hare Intl
$508American Airlines
Wed, Aug 26 - Wed, Sep 2
American Airlines Logo
11:31 am - 12:20 amMCI  Kansas City-LSE La Crosse
12h 49m2 stops Dallas/Fort Worth Chicago O'Hare Intl
American Airlines Logo
5:22 pm - 8:58 amLSE  La Crosse-MCI Kansas City
15h 36m2 stops Chicago O'Hare Intl Dallas/Fort Worth
$534American Airlines
Tue, Sep 15 - Wed, Sep 23
American Airlines Logo
3:53 pm - 12:22 amSGF  Springfield-Branson-LSE La Crosse
8h 29m2 stops Dallas/Fort Worth Chicago O'Hare Intl
American Airlines Logo
12:24 pm - 7:12 pmLSE  La Crosse-SGF Springfield-Branson
6h 48m1 stop Chicago O'Hare Intl
$546American Airlines
Tue, Aug 25 - Sat, Aug 29
American Airlines Logo
7:39 pm - 12:22 amMCI  Kansas City-LSE La Crosse
4h 43m1 stop Chicago O'Hare Intl
American Airlines Logo
6:00 am - 4:29 pmLSE  La Crosse-MCI Kansas City
10h 29m2 stops Chicago O'Hare Intl Dallas/Fort Worth
$546American Airlines
Wed, Aug 26 - Wed, Sep 2

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American Airlines flights from Missouri to La Crosse

Our best American Airlines deals on Missouri to La Crosse flight tickets
American Airlines
Sep 15
MCI5:13 amKansas City
6h 09m
1 stop
LSE11:22 amLa Crosse
Sep 23
LSE5:22 pmLa Crosse
7h 01m
1 stop
MCI12:23 amKansas City
$418
American Airlines
Sep 3
MCI5:00 amKansas City
19h 22m
1 stop
LSE12:22 amLa Crosse
Sep 7
LSE5:20 pmLa Crosse
15h 20m
1 stop
MCI8:40 amKansas City
$448
American Airlines
Sep 18
MCI5:13 amKansas City
19h 07m
1 stop
LSE12:20 amLa Crosse
Sep 20
LSE5:22 pmLa Crosse
15h 16m
1 stop
MCI8:38 amKansas City
$459

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Missouri to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Tue 9/15

5:13 am-11:22 am

1 stop6h 09m

La Crosse

Wed 9/23

5:22 pm-12:23 am

1 stop7h 01m

$418

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Thu 9/3

5:00 am-12:22 am

1 stop19h 22m

La Crosse

Mon 9/7

5:20 pm-8:40 am

1 stop15h 20m

$448

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Fri 9/18

5:13 am-12:20 am

1 stop19h 07m

La Crosse

Sun 9/20

5:22 pm-8:38 am

1 stop15h 16m

$459

SpringfieldLa Crosse

SGF Springfield-Branson - LSE La Crosse

SGFLSE

Springfield-Branson

Fri 11/13

10:38 am-12:17 am

1 stop13h 39m

La Crosse

Mon 11/16

6:01 am-4:52 pm

1 stop10h 51m

$486

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Tue 9/15

6:44 am-4:52 pm

2 stops10h 08m

La Crosse

Wed 9/23

5:22 pm-12:23 am

1 stop7h 01m

$501
Quickest round-trip

SpringfieldLa Crosse

SGF Springfield-Branson - LSE La Crosse

SGFLSE

Springfield-Branson

Tue 8/25

8:04 pm-12:22 am

1 stop4h 18m

La Crosse

Sat 8/29

6:04 am-10:04 am

1 stop4h 00m

$508

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Wed 8/26

5:00 am-11:31 am

1 stop6h 31m

La Crosse

Wed 9/2

12:19 pm-7:02 pm

1 stop6h 43m

$508

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Tue 9/15

11:31 am-12:20 am

2 stops12h 49m

La Crosse

Wed 9/23

5:22 pm-8:58 am

2 stops15h 36m

$534

SpringfieldLa Crosse

SGF Springfield-Branson - LSE La Crosse

SGFLSE

Springfield-Branson

Tue 8/25

3:53 pm-12:22 am

2 stops8h 29m

La Crosse

Sat 8/29

12:24 pm-7:12 pm

1 stop6h 48m

$546

Kansas CityLa Crosse

MCI Kansas City - LSE La Crosse

MCILSE

Kansas City

Wed 8/26

7:39 pm-12:22 am

1 stop4h 43m

La Crosse

Wed 9/2

6:00 am-4:29 pm

2 stops10h 29m

$546

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to La Crosse from

How to get the cheapest flight ticket from Missouri to La Crosse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Missouri to La Crosse?

American Airlines is the most popular carrier operating from Missouri to La Crosse

Cheap Missouri to La Crosse flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to La Crosse

Fastest flight time

4h 18m

Direct flights

None
The fastest flight from Missouri to La Crosse takes 4h 18m
There are no direct flights from Missouri to La Crosse. There are no popular flight routes from Missouri to La Crosse.
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Frequently asked questions about flying from Missouri to La Crosse

  • When did momondo last update prices for flights from Missouri to La Crosse Airport?

    Prices for flights from Missouri to La Crosse Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to La Crosse Airport?

  • How old do you have to be to fly from Missouri to La Crosse Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The travel and health documents required for your trip to La Crosse Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at La Crosse Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to La Crosse

Compare and see reviews for airlines that fly from Missouri to La Crosse with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $298Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Onalaska
Winona
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to La Crosse?

Finding the right flight to La Crosse from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to La Crosse quick and easy, saving you time and money.

Can I find flights from Missouri to La Crosse with flexible booking policies on momondo?

All flight searches from Missouri to La Crosse on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to La Crosse?

momondo helps you find the best flight between Missouri and La Crosse by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to La Crosse right now. Can momondo alert me if prices change?

Price alerts on flights to La Crosse from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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