What airlines fly to Florida Keys?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florida Keys from Missouri according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 33 per week as of September 2025. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, Frontier, and American Airlines are the most popular carriers operating from Missouri to Florida Keys

How long is the flight from Missouri to Florida Keys?

On average, it takes 11h 25m to fly from Missouri to Florida Keys if you fly out of St. Louis (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Kansas City and into Copenhagen, then the flight time is around 13h 31m.

When did momondo last update prices for flights from Missouri to Florida Keys?

Prices for flights from Missouri to Florida Keys refresh daily.

How many operators does momondo search for flights from Missouri to Florida Keys?

The number of operators available for flights from Missouri to Florida Keys is 6 as of September 2025.

How old do you have to be to fly from Missouri to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$80 Cheap Flights from Missouri to Florida Keys in 2025/26

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Find the cheapest flights from Missouri to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

5:23 am - 9:10 amSTL-MIA

2h 47mnonstop

10:01 pm - 11:56 pmMIA-STL

2h 55mnonstop

$163American Airlines

Find Deal

Tue, Oct 21 - Tue, Oct 28

10:17 am - 5:33 pmSTL-MIA

6h 16m1 stop

6:43 pm - 9:32 amMIA-STL

15h 49m1 stop

$164Frontier

Find Deal

Thu, Oct 23 - Sun, Oct 26

10:17 am - 5:33 pmSTL-MIA

6h 16m1 stop

6:00 am - 9:07 amMIA-STL

28h 07m1 stop

$168Frontier

Find Deal

Sun, Oct 26 - Fri, Oct 31

5:23 am - 9:10 amSTL-MIA

2h 47mnonstop

10:01 pm - 11:56 pmMIA-STL

2h 55mnonstop

$169American Airlines

Find Deal

Tue, Oct 14 - Tue, Oct 21

4:15 pm - 9:50 pmMCI-MIA

4h 35m1 stop

6:00 am - 6:25 pmMIA-MCI

13h 25m2 stops

$190Southwest

Find Deal

Mon, Dec 8 - Fri, Dec 12

5:15 pm - 12:29 amSTL-MIA

6h 14m1 stop

6:00 am - 10:23 amMIA-STL

5h 23m1 stop

$197Delta

Find Deal

Sat, Nov 8 - Sat, Nov 15

5:15 pm - 12:29 amSTL-MIA

6h 14m1 stop

8:11 am - 12:35 pmMIA-STL

5h 24m1 stop

$198Delta

Find Deal

Tue, Oct 14 - Tue, Oct 21

9:40 am - 4:10 pmSTL-MIA

5h 30m1 stop

4:55 pm - 6:55 pmMIA-STL

3h 00mnonstop

$210Southwest

Find Deal

Tue, Nov 11 - Wed, Nov 12

8:55 am - 9:00 amMCI-EYW

23h 05m1 stop

10:02 am - 8:05 amEYW-MCI

23h 03m1 stop

$271Allegiant Air

Find Deal

Sun, Oct 5 - Wed, Oct 8

8:00 pm - 8:11 amSGF-EYW

11h 11m1 stop

9:36 pm - 8:48 amEYW-SGF

12h 12m1 stop

$305Allegiant Air

Find Deal

Thu, Nov 6 - Sun, Nov 9

American Airlines flights from Missouri to Florida Keys

Our best American Airlines deals on Missouri to Florida Keys flight tickets

American Airlines

Oct 21

STL5:23 amLambert-St Louis

2h 47m

MIA9:10 amMiami

Oct 28

MIA10:01 pmMiami

2h 55m

STL11:56 pmLambert-St Louis

$163

Find similar

American Airlines

Oct 14

STL5:23 amLambert-St Louis

2h 47m

MIA9:10 amMiami

Oct 21

MIA10:01 pmMiami

2h 55m

STL11:56 pmLambert-St Louis

$169

Find similar

American Airlines

Oct 14

STL5:23 amLambert-St Louis

2h 47m

MIA9:10 amMiami

Oct 21

MIA10:01 pmMiami

2h 55m

STL11:56 pmLambert-St Louis

$179

Find similar

Delta flights from Missouri to Florida Keys

Our best Delta deals on Missouri to Florida Keys flight tickets

Delta

Nov 8

STL5:15 pmLambert-St Louis

6h 14m

1 stop

MIA12:29 amMiami

Nov 15

MIA6:00 amMiami

5h 23m

1 stop

STL10:23 amLambert-St Louis

$197

Find similar

Delta

Oct 14

STL5:15 pmLambert-St Louis

6h 14m

1 stop

MIA12:29 amMiami

Oct 21

MIA8:11 amMiami

5h 24m

1 stop

STL12:35 pmLambert-St Louis

$198

Find similar

Delta

Oct 14

STL5:15 pmLambert-St Louis

6h 14m

1 stop

MIA12:29 amMiami

Oct 21

MIA6:00 amMiami

5h 26m

1 stop

STL10:26 amLambert-St Louis

$199

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 10/21

5:23 am-9:10 am

Nonstop2h 47m

Miami

Tue 10/28

10:01 pm-11:56 pm

Nonstop2h 55m

$163

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 10/23

10:17 am-5:33 pm

1 stop6h 16m

Miami

Sun 10/26

6:43 pm-9:32 am

1 stop15h 49m

$164

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sun 10/26

10:17 am-5:33 pm

1 stop6h 16m

Miami

Fri 10/31

6:00 am-9:07 am

1 stop28h 07m

$168

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 10/14

5:23 am-9:10 am

Nonstop2h 47m

Miami

Tue 10/21

10:01 pm-11:56 pm

Nonstop2h 55m

$169

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Mon 12/8

4:15 pm-9:50 pm

1 stop4h 35m

Miami

Fri 12/12

6:00 am-6:25 pm

2 stops13h 25m

$190

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 11/8

5:15 pm-12:29 am

1 stop6h 14m

Miami

Sat 11/15

6:00 am-10:23 am

1 stop5h 23m

$197

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 10/14

5:15 pm-12:29 am

1 stop6h 14m

Miami

Tue 10/21

8:11 am-12:35 pm

1 stop5h 24m

$198

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 11/11

9:40 am-4:10 pm

1 stop5h 30m

Miami

Wed 11/12

4:55 pm-6:55 pm

Nonstop3h 00m

$210

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Sun 10/5

8:55 am-9:00 am

1 stop23h 05m

Key West

Wed 10/8

10:02 am-8:05 am

1 stop23h 03m

$271

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

Thu 11/6

8:00 pm-8:11 am

1 stop11h 11m

Key West

Sun 11/9

9:36 pm-8:48 am

1 stop12h 12m

$305

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $336.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Wednesday when prices can be found for as low as $560. The most expensive day to fly to Florida Keys is Saturday, with ticket prices averaging around $595.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from Missouri to Florida Keys in the evening for as low as $482. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights at noon are often more expensive with an average ticket price of $605.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $406 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Missouri for as low as $345 on momondo.

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Fastest flight time	2h 40m
Direct flights	Every day
Airports in Florida Keys	1 airport

The fastest flight from Missouri to Florida Keys takes 2h 40m

Direct flights go from Missouri to Florida Keys every day.

There is 1 airport near Florida Keys: Miami (MIA)

Search flight deals

When did momondo last update prices for flights from Missouri to Florida Keys?
Prices for flights from Missouri to Florida Keys refresh daily.
How many operators does momondo search for flights from Missouri to Florida Keys?
The number of operators available for flights from Missouri to Florida Keys is 6 as of September 2025.
How old do you have to be to fly from Missouri to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Missouri to Florida Keys is Boeing 737 MAX 8, representing 18.86% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 18.83%, Boeing 737-700 Passenger/BBJ1 (winglets) at 11.12%, and Boeing 737-800 at 6.50%.

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $189	Free Cancellation	Rating 7.9 7,974 reviews	Search Delta flights
United Airlines	PriceFrom $245	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights
American Airlines	PriceFrom $246	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Florida Keys for you.

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Florida Keys flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from Missouri.

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Thu 10/23

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Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Flights to New Yorkfrom $50

Flights to Los Angelesfrom $44

Flights to Miamifrom $49

Flights to Chicagofrom $60

Flights to Orlandofrom $56

Flights to Las Vegasfrom $44

Flights to San Franciscofrom $60

Flights to Washington, D.C.from $56

Flights to Bostonfrom $67

Flights to Atlantafrom $51

Flights to Dallasfrom $59

Flights to Seattlefrom $102

Cheap flights from Missouri to Florida Keys from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Florida Keys departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from Missouri to Florida Keys

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

American Airlines flights from Missouri to Florida Keys

Our best American Airlines deals on Missouri to Florida Keys flight tickets

Delta flights from Missouri to Florida Keys

Our best Delta deals on Missouri to Florida Keys flight tickets

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Use the filters below to find and compare flights from Missouri to Florida Keys that are best for you.

See travel insights to Florida Keys from

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $336.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Wednesday when prices can be found for as low as $560. The most expensive day to fly to Florida Keys is Saturday, with ticket prices averaging around $595.

What is the cheapest time of day to depart on your flight to Florida Keys?

How far in advance should I book a flight to Florida Keys?

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, Frontier, and American Airlines are the most popular carriers operating from Missouri to Florida Keys

What airlines fly to Florida Keys?

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 33 per week as of September 2025. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

How long is the flight from Missouri to Florida Keys?

On average, it takes 11h 25m to fly from Missouri to Florida Keys if you fly out of St. Louis (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Kansas City and into Copenhagen, then the flight time is around 13h 31m.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Fastest flight time

Direct flights

Airports in Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?

How many operators does momondo search for flights from Missouri to Florida Keys?

How old do you have to be to fly from Missouri to Florida Keys?

What documentation or ID do you need to fly to Florida Keys?

What is the most popular plane model from Missouri to Florida Keys?

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

How can momondo help me find flights from Missouri to Florida Keys?

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo