How long is the flight from Missouri to Florida Keys?

On average, it takes 15h 25m to fly from Missouri to Florida Keys if you fly out of St. Louis (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Kansas City and into Copenhagen, then the flight time is around 16h 12m.

What airlines fly to Florida Keys?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florida Keys from Missouri according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 36 per week as of August 2026. The most frequent departure day is Wed, with 28% of weekly flights leaving on this day.

What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, Delta, and American Airlines are the most popular carriers operating from Missouri to Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?

Prices for flights from Missouri to Florida Keys refresh daily.

How many operators does momondo search for flights from Missouri to Florida Keys?

The number of operators available for flights from Missouri to Florida Keys is 6 as of August 2026.

How old do you have to be to fly from Missouri to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$62 Cheap Flights from Missouri to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:29 pm - 10:19 amSTL Lambert-St Louis-EYW Key West

42h 50m2 stops Atlanta Hartsfield-Jackson Orlando

10:59 am - 4:34 pmEYW Key West-STL Lambert-St Louis

6h 35m1 stop Orlando

$238Multiple Airlines

Fri, Sep 25 - Fri, Oct 2

5:19 pm - 10:19 amSTL Lambert-St Louis-EYW Key West

16h 00m1 stop Orlando

10:59 am - 9:40 amEYW Key West-STL Lambert-St Louis

23h 41m2 stops Orlando Atlanta Hartsfield-Jackson

$240Multiple Airlines

Sun, Oct 4 - Thu, Oct 8

12:30 pm - 4:10 pmSTL Lambert-St Louis-MIA Miami

2h 40mnonstop

7:00 am - 10:40 amMIA Miami-STL Lambert-St Louis

4h 40m1 stop Orlando

$270Southwest

Thu, Sep 10 - Thu, Sep 17

4:55 pm - 10:10 pmSTL Lambert-St Louis-MIA Miami

4h 15m1 stop Orlando

7:45 am - 9:30 amMIA Miami-STL Lambert-St Louis

2h 45mnonstop

$270Southwest

Mon, Sep 7 - Sat, Sep 12

8:10 pm - 5:48 amSTL Lambert-St Louis-MIA Miami

8h 38m1 stop Denver Intl

7:20 am - 7:15 pmMIA Miami-STL Lambert-St Louis

12h 55m1 stop Denver Intl

$271Frontier

Fri, Oct 9 - Sat, Oct 17

5:19 pm - 10:00 pmSTL Lambert-St Louis-MIA Miami

27h 41m2 stops Orlando Dallas/Fort Worth

9:30 pm - 1:10 pmMIA Miami-STL Lambert-St Louis

16h 40m1 stop Atlanta Hartsfield-Jackson

$272Frontier

Sun, Sep 27 - Thu, Oct 1

5:23 pm - 12:47 amSTL Lambert-St Louis-MIA Miami

6h 24m1 stop Atlanta Hartsfield-Jackson

7:00 am - 11:56 amMIA Miami-STL Lambert-St Louis

5h 56m1 stop Atlanta Hartsfield-Jackson

$275Delta

Wed, Sep 2 - Sat, Sep 5

10:00 am - 5:29 pmSTL Lambert-St Louis-MIA Miami

6h 29m1 stop Atlanta Hartsfield-Jackson

7:45 pm - 11:56 pmMIA Miami-STL Lambert-St Louis

5h 11m1 stop Atlanta Hartsfield-Jackson

$275Delta

Thu, Dec 10 - Mon, Dec 14

5:00 am - 12:59 pmSTL Lambert-St Louis-MIA Miami

6h 59m1 stop Chicago O'Hare Intl

7:54 pm - 9:59 pmMIA Miami-STL Lambert-St Louis

3h 05mnonstop

$275American Airlines

Fri, Oct 2 - Thu, Oct 8

5:00 am - 12:59 pmSTL Lambert-St Louis-MIA Miami

6h 59m1 stop Chicago O'Hare Intl

9:55 pm - 11:59 pmMIA Miami-STL Lambert-St Louis

3h 04mnonstop

$275American Airlines

Fri, Sep 18 - Thu, Sep 24

Cheap last minute flights

Enter your travel dates to find the best prices.

4:57 pm - 11:58 pmSTL Lambert-St Louis-MIA Miami

6h 01m1 stop Atlanta Hartsfield-Jackson

6:50 am - 4:16 pmMIA Miami-STL Lambert-St Louis

10h 26m1 stop Dallas/Fort Worth

$288Frontier

Sat, Aug 15 - Tue, Aug 18

4:57 pm - 11:58 pmSTL Lambert-St Louis-MIA Miami

6h 01m1 stop Atlanta Hartsfield-Jackson

8:10 am - 5:22 pmMIA Miami-STL Lambert-St Louis

10h 12m1 stop Atlanta Hartsfield-Jackson

$305Frontier

Sat, Aug 15 - Fri, Aug 21

5:00 am - 8:53 amSTL Lambert-St Louis-MIA Miami

2h 53mnonstop

8:40 pm - 10:40 pmMIA Miami-STL Lambert-St Louis

3h 00mnonstop

$407American Airlines

Sat, Aug 15 - Sat, Aug 22

11:35 am - 3:29 pmSTL Lambert-St Louis-MIA Miami

2h 54mnonstop

8:41 am - 10:39 amMIA Miami-STL Lambert-St Louis

2h 58mnonstop

$407American Airlines

Sat, Aug 15 - Tue, Aug 18

11:35 am - 3:15 pmSTL Lambert-St Louis-MIA Miami

2h 40mnonstop

7:00 am - 3:30 pmMIA Miami-STL Lambert-St Louis

9h 30m2 stops Orlando Baltimore/Washington

$422Southwest

Tue, Aug 18 - Sat, Aug 22

8:25 am - 5:05 pmSTL Lambert-St Louis-MIA Miami

7h 40m1 stop Austin Bergstrom

7:00 am - 12:35 pmMIA Miami-STL Lambert-St Louis

6h 35m2 stops Orlando Atlanta Hartsfield-Jackson

$432Southwest

Tue, Aug 18 - Sat, Aug 22

9:15 am - 2:54 pmSTL Lambert-St Louis-MIA Miami

4h 39m1 stop Atlanta Hartsfield-Jackson

6:00 am - 9:54 amMIA Miami-STL Lambert-St Louis

4h 54m1 stop Atlanta Hartsfield-Jackson

$454Delta

Tue, Aug 18 - Thu, Aug 20

8:42 am - 3:42 pmSGF Springfield-Branson-EYW Key West

6h 00m1 stop Tampa St. Petersburg

4:35 pm - 7:14 pmEYW Key West-SGF Springfield-Branson

27h 39m1 stop Tampa St. Petersburg

$463Allegiant Air

Fri, Aug 14 - Sat, Aug 15

10:44 am - 6:40 pmSTL Lambert-St Louis-MIA Miami

6h 56m1 stop Atlanta Hartsfield-Jackson

12:05 pm - 5:53 pmMIA Miami-STL Lambert-St Louis

6h 48m1 stop Atlanta Hartsfield-Jackson

$477Delta

Sun, Aug 16 - Fri, Aug 21

8:42 am - 3:42 pmSGF Springfield-Branson-EYW Key West

6h 00m1 stop Tampa St. Petersburg

4:35 pm - 7:14 pmEYW Key West-SGF Springfield-Branson

27h 39m1 stop Tampa St. Petersburg

$527Allegiant Air

Fri, Aug 14 - Sat, Aug 15

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Southwest flights from Missouri to Florida Keys

Our best Southwest deals on Missouri to Florida Keys flight tickets

Southwest

Sep 7

STL4:55 pmLambert-St Louis

4h 15m

1 stop

MIA10:10 pmMiami

Sep 12

MIA7:45 amMiami

2h 45m

STL9:30 amLambert-St Louis

$270

Southwest

Aug 29

STL11:15 amLambert-St Louis

8h 00m

1 stop

MIA8:15 pmMiami

Aug 31

MIA7:00 amMiami

9h 20m

2 stops

STL3:20 pmLambert-St Louis

$277

Southwest

Sep 10

STL11:40 amLambert-St Louis

9h 30m

2 stops

MIA10:10 pmMiami

Sep 14

MIA6:20 amMiami

9h 50m

2 stops

STL3:10 pmLambert-St Louis

$282

Frontier flights from Missouri to Florida Keys

Our best Frontier deals on Missouri to Florida Keys flight tickets

Frontier

Oct 9

STL8:10 pmLambert-St Louis

8h 38m

1 stop

MIA5:48 amMiami

Oct 17

MIA7:20 amMiami

12h 55m

1 stop

STL7:15 pmLambert-St Louis

$271

Frontier

Nov 10

STL10:35 amLambert-St Louis

6h 37m

1 stop

MIA6:12 pmMiami

Nov 15

MIA7:20 amMiami

12h 55m

1 stop

STL7:15 pmLambert-St Louis

$273

Frontier

Aug 27

STL7:58 pmLambert-St Louis

7h 54m

1 stop

MIA4:52 amMiami

Aug 30

MIA8:10 amMiami

10h 12m

1 stop

STL5:22 pmLambert-St Louis

$274

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisKey West

STL Lambert-St Louis - EYW Key West

STLEYW

Lambert-St Louis

Fri 9/25

2:29 pm-10:19 am

2 stops42h 50m

Key West

Fri 10/2

10:59 am-4:34 pm

1 stop6h 35m

$238

St. LouisKey West

STL Lambert-St Louis - EYW Key West

STLEYW

Lambert-St Louis

Sun 10/4

5:19 pm-10:19 am

1 stop16h 00m

Key West

Thu 10/8

10:59 am-9:40 am

2 stops23h 41m

$240

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Thu 9/10

12:30 pm-4:10 pm

Nonstop2h 40m

Miami

Thu 9/17

7:00 am-10:40 am

1 stop4h 40m

$270

Quickest round-trip

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Mon 9/7

4:55 pm-10:10 pm

1 stop4h 15m

Miami

Sat 9/12

7:45 am-9:30 am

Nonstop2h 45m

$270

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Fri 10/9

8:10 pm-5:48 am

1 stop8h 38m

Miami

Sat 10/17

7:20 am-7:15 pm

1 stop12h 55m

$271

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Sun 9/27

5:19 pm-10:00 pm

2 stops27h 41m

Miami

Thu 10/1

9:30 pm-1:10 pm

1 stop16h 40m

$272

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Wed 9/2

5:23 pm-12:47 am

1 stop6h 24m

Miami

Sat 9/5

7:00 am-11:56 am

1 stop5h 56m

$275

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Thu 12/10

10:00 am-5:29 pm

1 stop6h 29m

Miami

Mon 12/14

7:45 pm-11:56 pm

1 stop5h 11m

$275

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Fri 10/2

5:00 am-12:59 pm

1 stop6h 59m

Miami

Thu 10/8

7:54 pm-9:59 pm

Nonstop3h 05m

$275

St. LouisMiami

STL Lambert-St Louis - MIA Miami

STLMIA

Lambert-St Louis

Fri 9/18

5:00 am-12:59 pm

1 stop6h 59m

Miami

Thu 9/24

9:55 pm-11:59 pm

Nonstop3h 04m

$275

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $379.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Monday when prices can be found for as low as $489. The most expensive day to fly to Florida Keys is Tuesday, with ticket prices averaging around $636.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is at noon. momondo users have found flights departing from Missouri to Florida Keys at noon for as low as $485. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the afternoon are often more expensive with an average ticket price of $584.

How far in advance should I book a flight from Missouri to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $407 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Missouri for as low as $342 on momondo.

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Fastest flight time	2h 35m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from Missouri to Florida Keys takes 2h 35m

Direct flights go from Missouri to Florida Keys every day.

There are 3 airports in Florida Keys. From Missouri there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from Missouri to Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?
Prices for flights from Missouri to Florida Keys refresh daily.
How many operators does momondo search for flights from Missouri to Florida Keys?
The number of operators available for flights from Missouri to Florida Keys is 6 as of August 2026.
How old do you have to be to fly from Missouri to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Missouri to Florida Keys is Boeing 737 MAX 8, representing 22.93% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 13.72%, Embraer 175 (Enhanced Winglets) at 7.56%, and Boeing 737-800 at 7.54%.

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $222	Free Cancellation	Rating 7.1 11,923 reviews	Search American Airlines flights
Delta	PriceFrom $242	Free Cancellation	Rating 7.8 8,502 reviews	Search Delta flights
United Airlines	PriceFrom $268	Free Cancellation	Rating 7.4 10,114 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Florida Keys for you.

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Florida Keys flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from Missouri.

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.