What airlines fly to Florida Keys?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florida Keys from Missouri according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 47 per week as of June 2026. The most frequent departure day is Sun, with 28% of weekly flights leaving on this day.

How long is the flight from Missouri to Florida Keys?

On average, it takes 12h 45m to fly from Missouri to Florida Keys if you fly out of St. Louis (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Kansas City and into Copenhagen, then the flight time is around 13h 52m.

What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, Delta, and Allegiant Air are the most popular carriers operating from Missouri to Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?

Prices for flights from Missouri to Florida Keys refresh daily.

How many operators does momondo search for flights from Missouri to Florida Keys?

The number of operators available for flights from Missouri to Florida Keys is 6 as of June 2026.

How old do you have to be to fly from Missouri to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$84 Cheap Flights from Missouri to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:42 am - 3:42 pm

SGF

EYW

6h 00m

1 stop

6:21 pm - 9:33 am

EYW

SGF

16h 12m

1 stop

$226Allegiant Air

Mon, Aug 17 - Thu, Aug 27

3:20 pm - 9:04 pm

SGF

MIA

4h 44m

1 stop

7:00 am - 10:53 am

MIA

SGF

4h 53m

1 stop

$227Delta

Thu, Aug 20 - Wed, Aug 26

5:02 pm - 11:25 am

STL

EYW

17h 23m

1 stop

10:04 am - 9:40 am

EYW

STL

24h 36m

2 stops

$230Multiple Airlines

Sat, Aug 22 - Sat, Sep 12

5:02 pm - 11:25 am

STL

EYW

17h 23m

1 stop

11:46 am - 5:22 pm

EYW

STL

30h 36m

2 stops

$246Multiple Airlines

Sat, Aug 22 - Wed, Aug 26

6:17 pm - 11:25 am

STL

EYW

40h 08m

2 stops

10:59 am - 7:39 pm

EYW

STL

9h 40m

1 stop

$267Multiple Airlines

Fri, Sep 4 - Thu, Sep 10

10:35 am - 9:04 pm

STL

MIA

9h 29m

1 stop

7:20 am - 7:15 pm

MIA

STL

12h 55m

1 stop

$276Frontier

Fri, Sep 11 - Mon, Sep 14

6:45 pm - 1:32 pm

STL

MIA

17h 47m

2 stops

10:09 pm - 9:40 am

MIA

STL

12h 31m

1 stop

$277Frontier

Sat, Sep 5 - Sat, Sep 12

12:45 pm - 4:25 pm

STL

MIA

2h 40mnonstop

6:45 am - 12:40 pm

MIA

STL

6h 55m

1 stop

$279Southwest

Wed, Jul 22 - Wed, Sep 2

5:00 am - 8:53 am

STL

MIA

2h 53mnonstop

8:41 am - 10:45 am

MIA

STL

3h 04mnonstop

$280American Airlines

Fri, Aug 7 - Sat, Aug 15

11:00 am - 2:46 pm

STL

MIA

2h 46mnonstop

8:40 pm - 10:40 pm

MIA

STL

3h 00mnonstop

$282American Airlines

Tue, Aug 4 - Fri, Aug 7

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Southwest flights from Missouri to Florida Keys

Our best Southwest deals on Missouri to Florida Keys flight tickets

Southwest

Jul 22

STL12:45 pmLambert-St Louis

2h 40m

MIA4:25 pmMiami

Sep 2

MIA6:45 amMiami

6h 55m

1 stop

STL12:40 pmLambert-St Louis

$279

Southwest

Aug 13

STL4:55 pmLambert-St Louis

4h 10m

1 stop

MIA10:05 pmMiami

Aug 15

MIA7:00 amMiami

6h 35m

2 stops

STL12:35 pmLambert-St Louis

$294

Southwest

Jul 22

STL1:45 pmLambert-St Louis

7h 30m

2 stops

MIA10:15 pmMiami

Sep 2

MIA9:15 amMiami

9h 40m

2 stops

STL5:55 pmLambert-St Louis

$299

United Airlines flights from Missouri to Florida Keys

Our best United Airlines deals on Missouri to Florida Keys flight tickets

United Airlines

Nov 12

COU11:15 amColumbia Regional

6h 30m

1 stop

MIA6:45 pmMiami

Nov 14

MIA8:05 amMiami

10h 18m

2 stops

COU5:23 pmColumbia Regional

$314

United Airlines

Sep 16

STL7:00 amLambert-St Louis

6h 46m

1 stop

MIA2:46 pmMiami

Sep 23

MIA7:00 amMiami

9h 38m

2 stops

STL3:38 pmLambert-St Louis

$318

United Airlines

Jul 23

COU3:25 pmColumbia Regional

6h 02m

1 stop

MIA10:27 pmMiami

Jul 27

MIA5:32 pmMiami

7h 01m

1 stop

COU11:33 pmColumbia Regional

$332

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

Mon 8/17

8:42 am-3:42 pm

1 stop6h 00m

Key West

Thu 8/27

6:21 pm-9:33 am

1 stop16h 12m

$226

SpringfieldMiami

SGF - MIA

SGFMIA

Springfield-Branson

Thu 8/20

3:20 pm-9:04 pm

1 stop4h 44m

Miami

Wed 8/26

7:00 am-10:53 am

1 stop4h 53m

$227

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 8/22

5:02 pm-11:25 am

1 stop17h 23m

Key West

Sat 9/12

10:04 am-9:40 am

2 stops24h 36m

$230

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 8/22

5:02 pm-11:25 am

1 stop17h 23m

Key West

Wed 8/26

11:46 am-5:22 pm

2 stops30h 36m

$246

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 9/4

6:17 pm-11:25 am

2 stops40h 08m

Key West

Thu 9/10

10:59 am-7:39 pm

1 stop9h 40m

$267

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 9/11

10:35 am-9:04 pm

1 stop9h 29m

Miami

Mon 9/14

7:20 am-7:15 pm

1 stop12h 55m

$276

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 9/5

6:45 pm-1:32 pm

2 stops17h 47m

Miami

Sat 9/12

10:09 pm-9:40 am

1 stop12h 31m

$277

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 7/22

12:45 pm-4:25 pm

Nonstop2h 40m

Miami

Wed 9/2

6:45 am-12:40 pm

1 stop6h 55m

$279

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 8/7

5:00 am-8:53 am

Nonstop2h 53m

Miami

Sat 8/15

8:41 am-10:45 am

Nonstop3h 04m

$280

Quickest round-trip

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 8/4

11:00 am-2:46 pm

Nonstop2h 46m

Miami

Fri 8/7

8:40 pm-10:40 pm

Nonstop3h 00m

$282

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $86.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Friday when prices can be found for as low as $562. The most expensive day to fly to Florida Keys is Tuesday, with ticket prices averaging around $630.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from Missouri to Florida Keys in the evening for as low as $370. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $611.

How far in advance should I book a flight from Missouri to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $400 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Missouri for as low as $348 on momondo.

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Fastest flight time	2h 35m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from Missouri to Florida Keys takes 2h 35m

Direct flights go from Missouri to Florida Keys every day.

There are 3 airports in Florida Keys. From Missouri there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from Missouri to Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?
Prices for flights from Missouri to Florida Keys refresh daily.
How many operators does momondo search for flights from Missouri to Florida Keys?
The number of operators available for flights from Missouri to Florida Keys is 6 as of June 2026.
How old do you have to be to fly from Missouri to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Missouri to Florida Keys is Boeing 737 MAX 8, representing 24.21% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 13.98%, Boeing 737-800 at 8.35%, and Airbus A319 at 6.97%.

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $222	Free Cancellation	Rating 7.1 11,776 reviews	Search American Airlines flights
Delta	PriceFrom $230	Free Cancellation	Rating 7.8 8,455 reviews	Search Delta flights
United Airlines	PriceFrom $262	Free Cancellation	Rating 7.4 9,899 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Florida Keys for you.

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Florida Keys flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from Missouri.

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.