What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, Frontier, and Delta are the most popular carriers operating from Missouri to Florida Keys

What airlines fly to Florida Keys?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florida Keys from Missouri according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 62 per week as of March 2026. The most frequent departure day is Wed, with 21% of weekly flights leaving on this day.

How long is the flight from Missouri to Florida Keys?

On average, it takes 11h 14m to fly from Missouri to Florida Keys if you fly out of Kansas City (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of St. Louis and into Copenhagen, then the flight time is around 11h 33m.

When did momondo last update prices for flights from Missouri to Florida Keys?

Prices for flights from Missouri to Florida Keys refresh daily.

How many operators does momondo search for flights from Missouri to Florida Keys?

The number of operators available for flights from Missouri to Florida Keys is 7 as of March 2026.

How old do you have to be to fly from Missouri to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$71 Cheap Flights from Missouri to Florida Keys in 2026

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Find the cheapest flights from Missouri to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:53 am - 12:49 am

MCI

MIA

11h 56m

1 stop

6:00 am - 1:49 pm

MIA

MCI

8h 49m

1 stop

$205Frontier

Sun, May 3 - Fri, May 8

2:51 pm - 5:05 am

MCI

MIA

13h 14m

1 stop

7:00 am - 2:06 pm

MIA

MCI

8h 06m

1 stop

$206Frontier

Sat, Apr 25 - Sat, May 2

11:19 am - 10:31 pm

MCI

MIA

10h 12m

1 stop

7:00 am - 2:06 pm

MIA

MCI

32h 06m

2 stops

$208Multiple Airlines

Fri, Apr 24 - Fri, May 1

6:24 pm - 9:40 am

MCI

MIA

14h 16m

1 stop

8:10 am - 5:29 pm

MIA

MCI

10h 19m

1 stop

$212Multiple Airlines

Sat, May 9 - Sat, May 16

10:51 am - 5:23 pm

STL

EYW

5h 32m

1 stop

2:24 pm - 6:06 pm

EYW

STL

4h 42m

1 stop

$263Delta

Tue, Jul 7 - Tue, Jul 14

6:00 am - 4:08 pm

STL

EYW

9h 08m

2 stops

7:29 pm - 11:57 pm

EYW

STL

5h 28m

1 stop

$268American Airlines

Tue, Jul 7 - Tue, Jul 14

5:24 am - 9:15 am

STL

MIA

2h 51mnonstop

8:15 am - 10:16 am

MIA

STL

3h 01mnonstop

$275American Airlines

Wed, May 13 - Wed, May 20

7:45 pm - 3:51 pm

SGF

EYW

19h 06m

1 stop

4:17 pm - 8:01 am

EYW

SGF

16h 44m

1 stop

$276Allegiant Air

Thu, Jul 9 - Thu, Jul 16

1:02 pm - 7:40 pm

STL

EYW

5h 38m

1 stop

6:23 pm - 11:36 pm

EYW

STL

6h 13m

1 stop

$301Delta

Tue, Apr 14 - Tue, Apr 21

8:20 pm - 3:51 pm

SGF

EYW

18h 31m

1 stop

4:35 pm - 7:14 pm

EYW

SGF

27h 39m

1 stop

$323Allegiant Air

Sun, Aug 2 - Sat, Aug 8

American Airlines flights from Missouri to Florida Keys

Our best American Airlines deals on Missouri to Florida Keys flight tickets

American Airlines

Apr 22

MCI5:52 pmKansas City

3h 08m

MIA10:00 pmMiami

Apr 29

MIA7:50 pmMiami

3h 30m

MCI10:20 pmKansas City

$257

American Airlines

May 13

STL5:24 amLambert-St Louis

2h 51m

MIA9:15 amMiami

May 20

MIA8:15 amMiami

3h 01m

STL10:16 amLambert-St Louis

$275

American Airlines

Apr 15

STL6:29 amLambert-St Louis

6h 16m

1 stop

MIA1:45 pmMiami

Apr 22

MIA8:15 amMiami

3h 01m

STL10:16 amLambert-St Louis

$293

Southwest flights from Missouri to Florida Keys

Our best Southwest deals on Missouri to Florida Keys flight tickets

Southwest

Apr 15

STL1:10 pmLambert-St Louis

2h 40m

MIA4:50 pmMiami

Apr 21

MIA7:00 amMiami

4h 50m

1 stop

STL10:50 amLambert-St Louis

$285

Southwest

Apr 28

STL2:30 pmLambert-St Louis

5h 10m

1 stop

MIA8:40 pmMiami

Apr 29

MIA3:00 pmMiami

2h 55m

STL4:55 pmLambert-St Louis

$286

Southwest

May 5

STL5:30 amLambert-St Louis

5h 00m

1 stop

MIA11:30 amMiami

May 6

MIA7:00 amMiami

9h 15m

2 stops

STL3:15 pmLambert-St Louis

$300

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Sun 5/3

11:53 am-12:49 am

1 stop11h 56m

Miami

Fri 5/8

6:00 am-1:49 pm

1 stop8h 49m

$205

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Sat 4/25

2:51 pm-5:05 am

1 stop13h 14m

Miami

Sat 5/2

7:00 am-2:06 pm

1 stop8h 06m

$206

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Fri 4/24

11:19 am-10:31 pm

1 stop10h 12m

Miami

Fri 5/1

7:00 am-2:06 pm

2 stops32h 06m

$208

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Sat 5/9

6:24 pm-9:40 am

1 stop14h 16m

Miami

Sat 5/16

8:10 am-5:29 pm

1 stop10h 19m

$212

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 7/7

10:51 am-5:23 pm

1 stop5h 32m

Key West

Tue 7/14

2:24 pm-6:06 pm

1 stop4h 42m

$263

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 7/7

6:00 am-4:08 pm

2 stops9h 08m

Key West

Tue 7/14

7:29 pm-11:57 pm

1 stop5h 28m

$268

Quickest round-trip

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 5/13

5:24 am-9:15 am

Nonstop2h 51m

Miami

Wed 5/20

8:15 am-10:16 am

Nonstop3h 01m

$275

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

Thu 7/9

7:45 pm-3:51 pm

1 stop19h 06m

Key West

Thu 7/16

4:17 pm-8:01 am

1 stop16h 44m

$276

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 4/14

1:02 pm-7:40 pm

1 stop5h 38m

Key West

Tue 4/21

6:23 pm-11:36 pm

1 stop6h 13m

$301

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

Sun 8/2

8:20 pm-3:51 pm

1 stop18h 31m

Key West

Sat 8/8

4:35 pm-7:14 pm

1 stop27h 39m

$323

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $336.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Sunday when prices can be found for as low as $503. The most expensive day to fly to Florida Keys is Tuesday, with ticket prices averaging around $582.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from Missouri to Florida Keys in the evening for as low as $408. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $545.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $396 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Missouri for as low as $323 on momondo.

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Fastest flight time	2h 40m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from Missouri to Florida Keys takes 2h 40m

Direct flights go from Missouri to Florida Keys every day.

There are 3 airports in Florida Keys. From Missouri there are direct flights to Miami (MIA).

Search flight deals

When did momondo last update prices for flights from Missouri to Florida Keys?
Prices for flights from Missouri to Florida Keys refresh daily.
How many operators does momondo search for flights from Missouri to Florida Keys?
The number of operators available for flights from Missouri to Florida Keys is 7 as of March 2026.
How old do you have to be to fly from Missouri to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Missouri to Florida Keys is Boeing 737 MAX 8, representing 27.81% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 17.93%, Boeing 737-800 at 6.56%, and Embraer 175 at 5.83%.

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $164	Free Cancellation	Rating 7.9 8,340 reviews	Search Delta flights
American Airlines	PriceFrom $222	Free Cancellation	Rating 7.1 11,503 reviews	Search American Airlines flights
United Airlines	PriceFrom $262	Free Cancellation	Rating 7.4 9,491 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Florida Keys for you.

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Florida Keys flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from Missouri.

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.