What airlines fly to Florida Keys?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florida Keys from Missouri according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 30 per week as of August 2025. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.

How long is the flight from Missouri to Florida Keys?

On average, it takes 14h 10m to fly from Missouri to Florida Keys if you fly out of St. Louis (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Kansas City and into Copenhagen, then the flight time is around 20h 05m.

What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, American Airlines, and Delta are the most popular carriers operating from Missouri to Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?

Prices for flights from Missouri to Florida Keys refresh daily.

How many operators does momondo search for flights from Missouri to Florida Keys?

The number of operators available for flights from Missouri to Florida Keys is 6 as of August 2025.

How old do you have to be to fly from Missouri to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$73 Cheap Flights from Missouri to Florida Keys in 2025

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Find the cheapest flights from Missouri to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

5:28 am - 9:17 amSTL-MIA

2h 49mnonstop

10:09 pm - 11:59 pmMIA-STL

2h 50mnonstop

$145American Airlines

Find Deal

Wed, Sep 3 - Wed, Sep 10

5:55 pm - 9:35 pmSTL-MIA

2h 40mnonstop

5:45 am - 7:35 amMIA-STL

2h 50mnonstop

$152Southwest

Find Deal

Sat, Oct 25 - Sat, Nov 1

1:26 pm - 9:28 pmSTL-MIA

7h 02m1 stop

7:30 am - 12:31 pmMIA-STL

6h 01m1 stop

$197Delta

Find Deal

Wed, Sep 3 - Wed, Sep 10

2:30 pm - 9:18 amSTL-MIA

17h 48m1 stop

3:40 pm - 1:32 pmMIA-STL

22h 52m1 stop

$207Spirit Airlines

Find Deal

Sun, Aug 24 - Wed, Aug 27

2:14 pm - 9:28 pmMCI-MIA

6h 14m1 stop

7:30 pm - 11:54 pmMIA-MCI

5h 24m1 stop

$217Delta

Find Deal

Wed, Aug 27 - Wed, Sep 3

2:50 pm - 10:15 pmSGF-MIA

6h 25m1 stop

4:53 pm - 9:57 pmMIA-SGF

6h 04m1 stop

$217United Airlines

Find Deal

Thu, Sep 4 - Mon, Sep 8

1:47 pm - 9:55 pmSGF-MIA

7h 08m1 stop

4:16 pm - 10:15 pmMIA-SGF

6h 59m1 stop

$218United Airlines

Find Deal

Sat, Aug 23 - Thu, Sep 4

7:54 pm - 6:30 amSTL-MIA

9h 36m1 stop

7:05 am - 1:33 pmMIA-STL

7h 28m1 stop

$218Frontier

Find Deal

Sat, Aug 23 - Sat, Aug 30

3:02 pm - 11:26 pmSTL-MIA

7h 24m1 stop

6:45 am - 9:06 amMIA-STL

27h 21m1 stop

$225Frontier

Find Deal

Sat, Aug 30 - Sat, Sep 6

6:00 am - 7:21 pmMCI-MIA

12h 21m2 stops

7:54 pm - 11:07 pmMIA-MCI

28h 13m2 stops

$247Spirit Airlines

Find Deal

Tue, Sep 2 - Tue, Sep 9

American Airlines flights from Missouri to Florida Keys

Our best American Airlines deals on Missouri to Florida Keys flight tickets

American Airlines

Sep 3

STL5:28 amLambert-St Louis

2h 49m

MIA9:17 amMiami

Sep 10

MIA10:09 pmMiami

2h 50m

STL11:59 pmLambert-St Louis

$145

Find similar

American Airlines

Sep 17

STL5:28 amLambert-St Louis

2h 49m

MIA9:17 amMiami

Sep 24

MIA10:09 pmMiami

2h 50m

STL11:59 pmLambert-St Louis

$159

Find similar

American Airlines

Aug 27

MCI5:10 amKansas City

3h 10m

MIA9:20 amMiami

Sep 3

MIA9:31 pmMiami

3h 28m

MCI11:59 pmKansas City

$174

Find similar

Southwest flights from Missouri to Florida Keys

Our best Southwest deals on Missouri to Florida Keys flight tickets

Southwest

Oct 25

STL5:55 pmLambert-St Louis

2h 40m

MIA9:35 pmMiami

Nov 1

MIA5:45 amMiami

2h 50m

STL7:35 amLambert-St Louis

$152

Find similar

Southwest

Sep 9

STL10:20 amLambert-St Louis

2h 45m

MIA2:05 pmMiami

Sep 13

MIA5:50 amMiami

2h 50m

STL7:40 amLambert-St Louis

$177

Find similar

Southwest

Sep 6

STL5:55 pmLambert-St Louis

2h 45m

MIA9:40 pmMiami

Sep 13

MIA5:50 amMiami

2h 50m

STL7:40 amLambert-St Louis

$184

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 9/3

5:28 am-9:17 am

Nonstop2h 49m

Miami

Wed 9/10

10:09 pm-11:59 pm

Nonstop2h 50m

$145

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 10/25

5:55 pm-9:35 pm

Nonstop2h 40m

Miami

Sat 11/1

5:45 am-7:35 am

Nonstop2h 50m

$152

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 9/3

1:26 pm-9:28 pm

1 stop7h 02m

Miami

Wed 9/10

7:30 am-12:31 pm

1 stop6h 01m

$197

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sun 8/24

2:30 pm-9:18 am

1 stop17h 48m

Miami

Wed 8/27

3:40 pm-1:32 pm

1 stop22h 52m

$207

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Wed 8/27

2:14 pm-9:28 pm

1 stop6h 14m

Miami

Wed 9/3

7:30 pm-11:54 pm

1 stop5h 24m

$217

SpringfieldMiami

SGF - MIA

SGFMIA

Springfield-Branson

Thu 9/4

2:50 pm-10:15 pm

1 stop6h 25m

Miami

Mon 9/8

4:53 pm-9:57 pm

1 stop6h 04m

$217

SpringfieldMiami

SGF - MIA

SGFMIA

Springfield-Branson

Sat 8/23

1:47 pm-9:55 pm

1 stop7h 08m

Miami

Thu 9/4

4:16 pm-10:15 pm

1 stop6h 59m

$218

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 8/23

7:54 pm-6:30 am

1 stop9h 36m

Miami

Sat 8/30

7:05 am-1:33 pm

1 stop7h 28m

$218

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 8/30

3:02 pm-11:26 pm

1 stop7h 24m

Miami

Sat 9/6

6:45 am-9:06 am

1 stop27h 21m

$225

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Tue 9/2

6:00 am-7:21 pm

2 stops12h 21m

Miami

Tue 9/9

7:54 pm-11:07 pm

2 stops28h 13m

$247

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $356.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Wednesday when prices can be found for as low as $547. The most expensive day to fly to Florida Keys is Thursday, with ticket prices averaging around $589.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from Missouri to Florida Keys in the evening for as low as $482. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights at noon are often more expensive with an average ticket price of $596.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $402 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Missouri for as low as $350 on momondo.

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Best Price Found	$73
Fastest flight time	2h 40m
Direct flights	Every day
Airports in Florida Keys	1 airport

The best one-way flight to Florida Keys from Missouri in the past 72 hours is $73. The best round-trip flight deal from Missouri to Florida Keys found on momondo in the last 72 hours is $145.

The fastest flight from Missouri to Florida Keys takes 2h 40m

Direct flights go from Missouri to Florida Keys every day.

There is 1 airport near Florida Keys: Miami (MIA)

Search flight deals

When did momondo last update prices for flights from Missouri to Florida Keys?
Prices for flights from Missouri to Florida Keys refresh daily.
How many operators does momondo search for flights from Missouri to Florida Keys?
The number of operators available for flights from Missouri to Florida Keys is 6 as of August 2025.
How old do you have to be to fly from Missouri to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Missouri to Florida Keys is Boeing 737-800 Passenger/BBJ2 (winglets), representing 20.27% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 15.32%, Boeing 737-700 Passenger/BBJ1 (winglets) at 13.91%, and Airbus A319 at 6.09%.

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $189	Free Cancellation	Rating 8.0 7,985 reviews	Search Delta flights
American Airlines	PriceFrom $213	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $245	Free Cancellation	Rating 7.4 8,917 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Florida Keys for you.

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Florida Keys flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from Missouri.

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Flights to New Yorkfrom $57

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Flights to Orlandofrom $60

Flights to Las Vegasfrom $21

Flights to San Franciscofrom $68

Flights to Washington, D.C.from $57

Flights to Bostonfrom $78

Flights to Atlantafrom $48

Flights to Dallasfrom $58

Flights to Seattlefrom $95

Cheap flights from Missouri to Florida Keys from $73

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Florida Keys departing on 9/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Missouri to Florida Keys

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

American Airlines flights from Missouri to Florida Keys

Our best American Airlines deals on Missouri to Florida Keys flight tickets

Southwest flights from Missouri to Florida Keys

Our best Southwest deals on Missouri to Florida Keys flight tickets

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Use the filters below to find and compare flights from Missouri to Florida Keys that are best for you.

See travel insights to Florida Keys from

How to get the cheapest flight ticket from Missouri to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Missouri averaging around $356.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Missouri to Florida Keys is on a Wednesday when prices can be found for as low as $547. The most expensive day to fly to Florida Keys is Thursday, with ticket prices averaging around $589.

What is the cheapest time of day to depart on your flight to Florida Keys?

How far in advance should I book a flight to Florida Keys?

Can stopping save me money on Missouri to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Missouri to Florida Keys.

What is the cheapest airline that flies from Missouri to Florida Keys?

Southwest, American Airlines, and Delta are the most popular carriers operating from Missouri to Florida Keys

What airlines fly to Florida Keys?

How many flights depart from Missouri to Florida Keys on average per week?

The number of flights available between Missouri and Florida Keys is 30 per week as of August 2025. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.

How long is the flight from Missouri to Florida Keys?

On average, it takes 14h 10m to fly from Missouri to Florida Keys if you fly out of St. Louis (the most popular airport in Missouri) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Kansas City and into Copenhagen, then the flight time is around 20h 05m.

Cheap Missouri to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florida Keys

Best Price Found

Fastest flight time

Direct flights

Airports in Florida Keys

When did momondo last update prices for flights from Missouri to Florida Keys?

How many operators does momondo search for flights from Missouri to Florida Keys?

How old do you have to be to fly from Missouri to Florida Keys?

What documentation or ID do you need to fly to Florida Keys?

What is the most popular plane model from Missouri to Florida Keys?

Best airlines flying from Missouri to Florida Keys

Compare and see reviews for airlines that fly from Missouri to Florida Keys with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florida Keys?

Can I find flights from Missouri to Florida Keys with flexible booking policies on momondo?

How can momondo help me find flights from Missouri to Florida Keys?

I’m not ready to book a flight from Missouri to Florida Keys right now. Can momondo alert me if prices change?

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo