What airlines fly to Knoxville?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Knoxville from Missoula according to our data. American Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?

As of October 2025, there are 2 operators available to choose from for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$384 Cheap Flights from Missoula to Knoxville in 2025/26

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5:01 am - 8:00 pmMSO-TYS

12h 59m2 stops

1:27 pm - 11:29 pmTYS-MSO

12h 02m2 stops

$384Delta

Find Deal

mié., dic. 10 - sáb., dic. 13

5:01 am - 8:00 pmMSO-TYS

12h 59m2 stops

3:50 pm - 12:33 pmTYS-MSO

22h 43m2 stops

$417Delta

Find Deal

mié., dic. 10 - sáb., dic. 13

7:00 am - 3:32 pmMSO-TYS

6h 32m1 stop

9:04 am - 8:02 pmTYS-MSO

12h 58m2 stops

$514American Airlines

Find Deal

mié., dic. 10 - sáb., dic. 13

5:01 am - 8:00 pmMSO-TYS

12h 59m2 stops

8:30 am - 9:53 pmTYS-MSO

15h 23m1 stop

$563Delta

Find Deal

mié., dic. 10 - sáb., dic. 13

7:00 am - 3:32 pmMSO-TYS

6h 32m1 stop

12:10 pm - 8:02 pmTYS-MSO

9h 52m1 stop

$578American Airlines

Find Deal

mié., dic. 10 - sáb., dic. 13

2:35 pm - 10:30 pmMSO-TYS

5h 55m1 stop

8:50 am - 1:33 pmTYS-MSO

6h 43m1 stop

$590United Airlines

Find Deal

mié., dic. 10 - sáb., dic. 13

5:25 am - 8:00 pmMSO-TYS

12h 35m2 stops

12:49 pm - 12:19 amTYS-MSO

13h 30m2 stops

$712Delta

Find Deal

mié., nov. 12 - mar., nov. 18

6:20 am - 10:30 pmMSO-TYS

14h 10m1 stop

1:52 pm - 1:33 pmTYS-MSO

25h 41m2 stops

$750United Airlines

Find Deal

dom., nov. 23 - mar., dic. 2

6:02 am - 9:33 pmMSO-TYS

13h 31m2 stops

3:37 pm - 12:32 pmTYS-MSO

22h 55m2 stops

$768Alaska Airlines

Find Deal

dom., nov. 23 - mar., dic. 2

6:02 am - 9:33 pmMSO-TYS

13h 31m2 stops

3:37 pm - 1:34 pmTYS-MSO

23h 57m3 stops

$773Alaska Airlines

Find Deal

dom., nov. 23 - mar., dic. 2

Delta flights from Missoula to Knoxville

Our best Delta deals on Missoula to Knoxville flight tickets

Delta

Dec 10

MSO5:01 amMissoula Johnson-Bell Field

12h 59m

2 stops

TYS8:00 pmKnoxville McGhee Tyson

Dec 13

TYS1:27 pmKnoxville McGhee Tyson

12h 02m

2 stops

MSO11:29 pmMissoula Johnson-Bell Field

$384

Find similar

Delta

Dec 10

MSO5:01 amMissoula Johnson-Bell Field

12h 59m

2 stops

TYS8:00 pmKnoxville McGhee Tyson

Dec 13

TYS3:50 pmKnoxville McGhee Tyson

22h 43m

2 stops

MSO12:33 pmMissoula Johnson-Bell Field

$417

Find similar

Delta

Dec 10

MSO5:01 amMissoula Johnson-Bell Field

12h 59m

2 stops

TYS8:00 pmKnoxville McGhee Tyson

Dec 13

TYS8:30 amKnoxville McGhee Tyson

15h 23m

1 stop

MSO9:53 pmMissoula Johnson-Bell Field

$563

Find similar

American Airlines flights from Missoula to Knoxville

Our best American Airlines deals on Missoula to Knoxville flight tickets

American Airlines

Dec 10

MSO7:00 amMissoula Johnson-Bell Field

6h 32m

1 stop

TYS3:32 pmKnoxville McGhee Tyson

Dec 13

TYS9:04 amKnoxville McGhee Tyson

12h 58m

2 stops

MSO8:02 pmMissoula Johnson-Bell Field

$514

Find similar

American Airlines

Dec 10

MSO7:00 amMissoula Johnson-Bell Field

6h 32m

1 stop

TYS3:32 pmKnoxville McGhee Tyson

Dec 13

TYS12:10 pmKnoxville McGhee Tyson

9h 52m

1 stop

MSO8:02 pmMissoula Johnson-Bell Field

$578

Find similar

American Airlines

Nov 24

MSO7:00 amMissoula Johnson-Bell Field

15h 20m

1 stop

TYS12:20 amKnoxville McGhee Tyson

Dec 2

TYS5:10 amKnoxville McGhee Tyson

17h 24m

1 stop

MSO8:34 pmMissoula Johnson-Bell Field

$847

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 12/10

5:01 am-8:00 pm

2 stops12h 59m

Knoxville McGhee Tyson

sáb. 12/13

1:27 pm-11:29 pm

2 stops12h 02m

$384

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 12/10

5:01 am-8:00 pm

2 stops12h 59m

Knoxville McGhee Tyson

sáb. 12/13

3:50 pm-12:33 pm

2 stops22h 43m

$417

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 12/10

7:00 am-3:32 pm

1 stop6h 32m

Knoxville McGhee Tyson

sáb. 12/13

9:04 am-8:02 pm

2 stops12h 58m

$514

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 12/10

5:01 am-8:00 pm

2 stops12h 59m

Knoxville McGhee Tyson

sáb. 12/13

8:30 am-9:53 pm

1 stop15h 23m

$563

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 12/10

7:00 am-3:32 pm

1 stop6h 32m

Knoxville McGhee Tyson

sáb. 12/13

12:10 pm-8:02 pm

1 stop9h 52m

$578

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 12/10

2:35 pm-10:30 pm

1 stop5h 55m

Knoxville McGhee Tyson

sáb. 12/13

8:50 am-1:33 pm

1 stop6h 43m

$590

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 11/12

5:25 am-8:00 pm

2 stops12h 35m

Knoxville McGhee Tyson

mar. 11/18

12:49 pm-12:19 am

2 stops13h 30m

$712

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

dom. 11/23

6:20 am-10:30 pm

1 stop14h 10m

Knoxville McGhee Tyson

mar. 12/2

1:52 pm-1:33 pm

2 stops25h 41m

$750

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

dom. 11/23

6:02 am-9:33 pm

2 stops13h 31m

Knoxville McGhee Tyson

mar. 12/2

3:37 pm-12:32 pm

2 stops22h 55m

$768

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

dom. 11/23

6:02 am-9:33 pm

2 stops13h 31m

Knoxville McGhee Tyson

mar. 12/2

3:37 pm-1:34 pm

3 stops23h 57m

$773

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Missoula to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Missoula, with most prices found around $264. If you aren’t able to travel during the month of August, then book flights to Knoxville from Missoula during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $333.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Missoula to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $572. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Missoula to Knoxville for around $710.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Missoula to Knoxville when you can find flight prices for as low as $608. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $622.

Can stopping save me money on Missoula to Knoxville flights?

You could potentially save up to 47% on your flight if you consider stops on a Missoula to Knoxville flight.

When to book flights from Missoula to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Missoula to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Missoula to Knoxville (MSO to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missoula to Knoxville

Direct flights	None

There are no direct flights from Missoula to Knoxville. There are no popular flight routes from Missoula to Knoxville.

Search flight deals

How far is Missoula Johnson-Bell Field to Knoxville McGhee Tyson by plane?
A flight from Missoula Johnson-Bell Field to Knoxville McGhee Tyson will travel around 1715.6 mi. By plane, this route typically takes 5h 55m.
When did momondo last update prices for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?
As of October 2025, there are 2 operators available to choose from for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Missoula to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Missoula to Knoxville is United Airlines, representing 52% of all bookings. The subsequent popular airline is American Airlines at 48%.

Best airlines flying from Missoula to Knoxville

Compare and see reviews for airlines that fly from Missoula to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $240	Free Cancellation	Rating 7.2 11,043 reviews		Search American Airlines flights
United Airlines	PriceFrom $360	Free Cancellation	Rating 7.4 8,968 reviews		Search United Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Alcoa

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Missoula to Knoxville?

Finding the right flight to Knoxville from Missoula is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Missoula to Knoxville with flexible booking policies on momondo?

All flight searches from Missoula to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missoula to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Missoula.

I’m not ready to book a flight from Missoula to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missoula to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.

An easier way to manage your Knoxville trip

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Cheap flights from Missoula to Knoxville from $384

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missoula to Knoxville departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from Missoula to Knoxville

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How to get the cheapest flight ticket from Missoula to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

Can stopping save me money on Missoula to Knoxville flights?

You could potentially save up to 47% on your flight if you consider stops on a Missoula to Knoxville flight.

What airlines fly to Knoxville?

When to book flights from Missoula to Knoxville

Cheap Missoula to Knoxville (MSO to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missoula to Knoxville

Direct flights

How far is Missoula Johnson-Bell Field to Knoxville McGhee Tyson by plane?

When did momondo last update prices for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Missoula Johnson-Bell Field Airport to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

What is the most popular airline from Missoula to Knoxville?

Best airlines flying from Missoula to Knoxville

Compare and see reviews for airlines that fly from Missoula to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Missoula to Knoxville?

Can I find flights from Missoula to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Missoula to Knoxville?

I’m not ready to book a flight from Missoula to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee