What is the cheapest airline that flies from Mississippi to South Carolina?

Southwest, American Airlines, and Delta are the most popular carriers operating from Mississippi to South Carolina

How long is the flight from Mississippi to South Carolina?

Flight times vary depending on what airport in Mississippi you fly out of and what airport in South Carolina you fly into. For example, flying from Jackson to Charleston takes 4h 41m on average. On the other hand, flying from Gulfport to Charleston takes 4h 54m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from Mississippi to South Carolina?

Prices for flights from Mississippi to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Mississippi to South Carolina?

There are 2 operators available for flights from Mississippi to South Carolina as of October 2026.

How old do you have to be to fly from Mississippi to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mississippi to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$199 Cheap Flights from Mississippi to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Mississippi to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:45 pm - 8:45 amGPT Gulfport Biloxi Regional-MYR Myrtle Beach Intl

12h 00m1 stop Orlando

2:42 pm - 8:51 amMYR Myrtle Beach Intl-GPT Gulfport Biloxi Regional

43h 09m2 stops Fort Lauderdale Tampa

$252Breeze Airways

Sun, Oct 25 - Wed, Oct 28

1:10 pm - 7:30 pmJAN Jackson-Evers Intl-CHS Charleston

5h 20m1 stop Nashville Intl

6:35 am - 12:30 pmCHS Charleston-JAN Jackson-Evers Intl

6h 55m2 stops Nashville Intl Houston Hobby

$264Southwest

Tue, Nov 3 - Tue, Nov 10

6:30 am - 5:25 pmJAN Jackson-Evers Intl-CHS Charleston

9h 55m2 stops Houston Hobby Nashville Intl

6:35 am - 12:30 pmCHS Charleston-JAN Jackson-Evers Intl

6h 55m2 stops Nashville Intl Houston Hobby

$269Southwest

Tue, Nov 3 - Tue, Nov 10

7:45 pm - 8:48 amGPT Gulfport Biloxi Regional-CHS Charleston

12h 03m1 stop Orlando

2:13 pm - 7:05 pmCHS Charleston-GPT Gulfport Biloxi Regional

5h 52m1 stop Orlando

$291Breeze Airways

Thu, Oct 29 - Sun, Nov 1

6:46 pm - 1:24 pmGPT Gulfport Biloxi Regional-CHS Charleston

17h 38m1 stop Tampa

10:13 pm - 8:51 amCHS Charleston-GPT Gulfport Biloxi Regional

11h 38m2 stops Fort Lauderdale Tampa

$298Breeze Airways

Fri, Oct 23 - Sun, Oct 25

7:45 pm - 8:48 amGPT Gulfport Biloxi Regional-CHS Charleston

12h 03m1 stop Orlando

10:13 pm - 8:51 amCHS Charleston-GPT Gulfport Biloxi Regional

11h 38m2 stops Fort Lauderdale Tampa

$305Breeze Airways

Thu, Oct 29 - Sun, Nov 1

1:04 pm - 7:48 pmJAN Jackson-Evers Intl-CHS Charleston

5h 44m1 stop Atlanta Hartsfield-Jackson

7:02 am - 9:54 amCHS Charleston-JAN Jackson-Evers Intl

3h 52m1 stop Atlanta Hartsfield-Jackson

$309Delta

Sat, Oct 31 - Sat, Nov 7

5:40 am - 1:45 pmJAN Jackson-Evers Intl-CHS Charleston

7h 05m2 stops Houston Hobby Dallas Love Field

6:40 am - 11:30 amCHS Charleston-JAN Jackson-Evers Intl

5h 50m1 stop Nashville Intl

$314Southwest

Sat, Oct 31 - Sat, Nov 7

1:54 pm - 8:06 pmGPT Gulfport Biloxi Regional-CHS Charleston

5h 12m1 stop Atlanta Hartsfield-Jackson

6:59 pm - 9:57 pmCHS Charleston-GPT Gulfport Biloxi Regional

3h 58m1 stop Atlanta Hartsfield-Jackson

$337Delta

Thu, Dec 10 - Sun, Dec 13

1:54 pm - 8:06 pmGPT Gulfport Biloxi Regional-CHS Charleston

5h 12m1 stop Atlanta Hartsfield-Jackson

5:10 am - 9:19 amCHS Charleston-GPT Gulfport Biloxi Regional

5h 09m1 stop Atlanta Hartsfield-Jackson

$337Delta

Thu, Dec 10 - Sun, Dec 13

Cheap last minute flights

Enter your travel dates to find the best prices.

7:45 pm - 8:45 amGPT Gulfport Biloxi Regional-MYR Myrtle Beach Intl

12h 00m1 stop Orlando

2:46 pm - 7:05 pmMYR Myrtle Beach Intl-GPT Gulfport Biloxi Regional

5h 19m1 stop Orlando

$259Breeze Airways

Sun, Oct 11 - Thu, Oct 22

7:45 pm - 8:45 amGPT Gulfport Biloxi Regional-MYR Myrtle Beach Intl

12h 00m1 stop Orlando

8:10 pm - 8:51 amMYR Myrtle Beach Intl-GPT Gulfport Biloxi Regional

13h 41m2 stops Fort Lauderdale Tampa

$343Breeze Airways

Sun, Oct 11 - Thu, Oct 22

6:05 pm - 11:59 pmGPT Gulfport Biloxi Regional-CHS Charleston

4h 54m1 stop Atlanta Hartsfield-Jackson

6:00 am - 9:17 amCHS Charleston-GPT Gulfport Biloxi Regional

4h 17m1 stop Atlanta Hartsfield-Jackson

$517Delta

Fri, Oct 9 - Sat, Oct 17

6:46 pm - 1:24 pmGPT Gulfport Biloxi Regional-CHS Charleston

17h 38m1 stop Tampa

2:09 pm - 8:51 amCHS Charleston-GPT Gulfport Biloxi Regional

43h 42m2 stops Akron/Canton Tampa

$533Breeze Airways

Fri, Oct 9 - Sat, Oct 17

6:05 pm - 11:59 pmGPT Gulfport Biloxi Regional-CHS Charleston

4h 54m1 stop Atlanta Hartsfield-Jackson

6:30 am - 9:17 amCHS Charleston-GPT Gulfport Biloxi Regional

3h 47m1 stop Atlanta Hartsfield-Jackson

$565Delta

Fri, Oct 9 - Mon, Oct 12

6:42 pm - 11:57 pmGPT Gulfport Biloxi Regional-CHS Charleston

4h 15m1 stop Charlotte Douglas

7:04 pm - 11:59 pmCHS Charleston-GPT Gulfport Biloxi Regional

5h 55m1 stop Charlotte Douglas

$565American Airlines

Fri, Oct 9 - Mon, Oct 12

1:04 pm - 5:14 pmJAN Jackson-Evers Intl-CAE Columbia Metropolitan

3h 10m1 stop Atlanta Hartsfield-Jackson

5:11 pm - 9:37 pmCAE Columbia Metropolitan-JAN Jackson-Evers Intl

5h 26m1 stop Atlanta Hartsfield-Jackson

$642Delta

Tue, Oct 6 - Sat, Oct 10

12:55 pm - 6:30 pmJAN Jackson-Evers Intl-GSP Greenville

4h 35m1 stop Nashville Intl

6:25 am - 9:55 pmGSP Greenville-JAN Jackson-Evers Intl

16h 30m2 stops Nashville Intl Houston Hobby

$676Southwest

Tue, Oct 6 - Thu, Oct 8

6:40 am - 8:05 pmJAN Jackson-Evers Intl-GSP Greenville

12h 25m2 stops Houston Hobby Baltimore/Washington

6:25 am - 9:55 pmGSP Greenville-JAN Jackson-Evers Intl

16h 30m2 stops Nashville Intl Houston Hobby

$682Southwest

Tue, Oct 6 - Thu, Oct 8

5:55 am - 8:00 pmJAN Jackson-Evers Intl-GSP Greenville

13h 05m2 stops Houston Hobby Nashville Intl

12:55 pm - 10:25 pmGSP Greenville-JAN Jackson-Evers Intl

10h 30m2 stops Baltimore/Washington Houston Hobby

$718Southwest

Fri, Oct 9 - Sun, Oct 11

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Southwest flights from Mississippi to South Carolina

Our best Southwest deals on Mississippi to South Carolina flight tickets

Southwest

Nov 3

JAN1:10 pmJackson-Evers Intl

5h 20m

1 stop

CHS7:30 pmCharleston

Nov 10

CHS6:35 amCharleston

6h 55m

2 stops

JAN12:30 pmJackson-Evers Intl

$264

Southwest

Nov 3

JAN6:30 amJackson-Evers Intl

9h 55m

2 stops

CHS5:25 pmCharleston

Nov 10

CHS6:35 amCharleston

6h 55m

2 stops

JAN12:30 pmJackson-Evers Intl

$269

Southwest

Oct 31

JAN5:40 amJackson-Evers Intl

7h 05m

2 stops

CHS1:45 pmCharleston

Nov 7

CHS6:40 amCharleston

5h 50m

1 stop

JAN11:30 amJackson-Evers Intl

$314

Breeze Airways flights from Mississippi to South Carolina

Our best Breeze Airways deals on Mississippi to South Carolina flight tickets

Breeze Airways

Oct 25

GPT7:45 pmGulfport Biloxi Regional

12h 00m

1 stop

MYR8:45 amMyrtle Beach Intl

Oct 28

MYR2:42 pmMyrtle Beach Intl

43h 09m

2 stops

GPT8:51 amGulfport Biloxi Regional

$252

Breeze Airways

Oct 11

GPT7:45 pmGulfport Biloxi Regional

12h 00m

1 stop

MYR8:45 amMyrtle Beach Intl

Oct 22

MYR2:46 pmMyrtle Beach Intl

5h 19m

1 stop

GPT7:05 pmGulfport Biloxi Regional

$259

Breeze Airways

Oct 29

GPT7:45 pmGulfport Biloxi Regional

12h 03m

1 stop

CHS8:48 amCharleston

Nov 1

CHS2:13 pmCharleston

5h 52m

1 stop

GPT7:05 pmGulfport Biloxi Regional

$291

momondo Fare Finder

Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportMyrtle Beach

GPT Gulfport Biloxi Regional - MYR Myrtle Beach Intl

GPTMYR

Gulfport Biloxi Regional

Sun 10/25

7:45 pm-8:45 am

1 stop12h 00m

Myrtle Beach Intl

Wed 10/28

2:42 pm-8:51 am

2 stops43h 09m

$252

JacksonCharleston

JAN Jackson-Evers Intl - CHS Charleston

JANCHS

Jackson-Evers Intl

Tue 11/3

1:10 pm-7:30 pm

1 stop5h 20m

Charleston

Tue 11/10

6:35 am-12:30 pm

2 stops6h 55m

$264

JacksonCharleston

JAN Jackson-Evers Intl - CHS Charleston

JANCHS

Jackson-Evers Intl

Tue 11/3

6:30 am-5:25 pm

2 stops9h 55m

Charleston

Tue 11/10

6:35 am-12:30 pm

2 stops6h 55m

$269

GulfportCharleston

GPT Gulfport Biloxi Regional - CHS Charleston

GPTCHS

Gulfport Biloxi Regional

Thu 10/29

7:45 pm-8:48 am

1 stop12h 03m

Charleston

Sun 11/1

2:13 pm-7:05 pm

1 stop5h 52m

$291

GulfportCharleston

GPT Gulfport Biloxi Regional - CHS Charleston

GPTCHS

Gulfport Biloxi Regional

Fri 10/23

6:46 pm-1:24 pm

1 stop17h 38m

Charleston

Sun 10/25

10:13 pm-8:51 am

2 stops11h 38m

$298

GulfportCharleston

GPT Gulfport Biloxi Regional - CHS Charleston

GPTCHS

Gulfport Biloxi Regional

Thu 10/29

7:45 pm-8:48 am

1 stop12h 03m

Charleston

Sun 11/1

10:13 pm-8:51 am

2 stops11h 38m

$305

JacksonCharleston

JAN Jackson-Evers Intl - CHS Charleston

JANCHS

Jackson-Evers Intl

Sat 10/31

1:04 pm-7:48 pm

1 stop5h 44m

Charleston

Sat 11/7

7:02 am-9:54 am

1 stop3h 52m

$309

JacksonCharleston

JAN Jackson-Evers Intl - CHS Charleston

JANCHS

Jackson-Evers Intl

Sat 10/31

5:40 am-1:45 pm

2 stops7h 05m

Charleston

Sat 11/7

6:40 am-11:30 am

1 stop5h 50m

$314

Quickest round-trip

GulfportCharleston

GPT Gulfport Biloxi Regional - CHS Charleston

GPTCHS

Gulfport Biloxi Regional

Thu 12/10

1:54 pm-8:06 pm

1 stop5h 12m

Charleston

Sun 12/13

6:59 pm-9:57 pm

1 stop3h 58m

$337

GulfportCharleston

GPT Gulfport Biloxi Regional - CHS Charleston

GPTCHS

Gulfport Biloxi Regional

Thu 12/10

1:54 pm-8:06 pm

1 stop5h 12m

Charleston

Sun 12/13

5:10 am-9:19 am

1 stop5h 09m

$337

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Mississippi to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Mississippi is in February. Flight prices, which tend to average around $303, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to South Carolina from Mississippi during September instead. Flights to South Carolina in September, while not as cheap as those in February, still average around $366.

Can stopping save me money on Mississippi to South Carolina flights?

You could potentially save up to 51% on your flight if you consider stops on a Mississippi to South Carolina flight.

Cheap Mississippi to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to South Carolina

Best Price Found	$199
Fastest flight time	1h 48m
Direct flights	None

The best one-way flight to South Carolina from Mississippi in the past 72 hours is $199. The best round-trip flight deal from Mississippi to South Carolina found on momondo in the last 72 hours is $252.

The fastest flight from Mississippi to South Carolina takes 1h 48m

There are no direct flights from Mississippi to South Carolina. There are no popular flight routes from Mississippi to South Carolina.

Search flight deals

Frequently asked questions about flying from Mississippi to South Carolina

When did momondo last update prices for flights from Mississippi to South Carolina?
Prices for flights from Mississippi to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Mississippi to South Carolina?
There are 2 operators available for flights from Mississippi to South Carolina as of October 2026.
How old do you have to be to fly from Mississippi to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mississippi to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Mississippi to South Carolina

Compare and see reviews for airlines that fly from Mississippi to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $248	Free Cancellation	Rating 7.8 8,629 reviews		Search Delta flights
Southwest	PriceFrom $254	Free Cancellation	Rating 7.9 4,216 reviews		Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to South Carolina?

Finding the right flight to South Carolina from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from Mississippi to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Mississippi with this policy.

How can momondo help me find flights from Mississippi to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Mississippi.

I’m not ready to book a flight from Mississippi to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.