Cheap flights from Mississippi to South Carolina from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to South Carolina departing on 3/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:14 am - 8:03 am
MEM
-
CLT
19h 49m
1 stop
Multiple Airlines Logo
9:28 pm - 10:15 am
CLT
-
MEM
13h 47m
1 stop
$171Multiple Airlines
Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
11:14 am - 8:03 am
MEM
-
CLT
19h 49m
1 stop
Multiple Airlines Logo
10:55 am - 5:09 pm
CLT
-
MEM
31h 14m
2 stops
$186Multiple Airlines
Wed, Mar 25 - Wed, Apr 1
Multiple Airlines Logo
11:15 am - 8:03 am
MEM
-
CLT
19h 48m
1 stop
Multiple Airlines Logo
1:59 pm - 6:20 pm
CLT
-
MEM
29h 21m
2 stops
$188Multiple Airlines
Tue, Mar 10 - Wed, Mar 18
Southwest Logo
5:05 pm - 10:50 pm
MEM
-
CLT
4h 45m
1 stop
Southwest Logo
7:20 pm - 11:20 pm
CLT
-
MEM
5h 00m
1 stop
$201Southwest
Thu, Mar 5 - Mon, Mar 16
Breeze Airways Logo
4:52 pm - 9:59 pm
MEM
-
CHS
4h 07m
1 stop
Breeze Airways Logo
12:57 pm - 4:12 pm
CHS
-
MEM
4h 15m
1 stop
$225Breeze Airways
Sun, Mar 29 - Thu, Apr 2
American Airlines Logo
1:30 pm - 7:03 pm
BTR
-
CHS
4h 33m
1 stop
American Airlines Logo
3:45 pm - 8:59 pm
CHS
-
BTR
6h 14m
1 stop
$279American Airlines
Tue, Feb 24 - Sat, Feb 28
American Airlines Logo
5:00 am - 5:20 pm
BTR
-
CHS
11h 20m
2 stops
American Airlines Logo
3:45 pm - 8:59 pm
CHS
-
BTR
6h 14m
1 stop
$284American Airlines
Tue, Feb 24 - Sat, Feb 28
Southwest Logo
12:30 pm - 9:20 pm
MEM
-
SAV
7h 50m
1 stop
Southwest Logo
6:40 am - 9:05 am
SAV
-
MEM
3h 25m
1 stop
$309Southwest
Thu, Apr 30 - Tue, May 5
Delta Logo
7:05 pm - 12:16 am
BTR
-
CHS
4h 11m
1 stop
Delta Logo
6:09 pm - 10:03 pm
CHS
-
BTR
4h 54m
1 stop
$311Delta
Thu, Mar 26 - Mon, Mar 30
Delta Logo
12:07 pm - 6:27 pm
MEM
-
CAE
5h 20m
1 stop
Delta Logo
8:28 am - 11:02 am
CAE
-
MEM
3h 34m
1 stop
$343Delta
Fri, Mar 20 - Sun, Mar 22

Spirit Airlines flights from Mississippi to South Carolina

Our best Spirit Airlines deals on Mississippi to South Carolina flight tickets
Spirit Airlines
May 20
MEM11:14 amMemphis
6h 09m
1 stop
CLT6:23 pmCharlotte Douglas
May 26
CLT6:30 amCharlotte Douglas
4h 49m
1 stop
MEM10:19 amMemphis
$218
Spirit Airlines
Mar 31
MEM11:14 amMemphis
7h 34m
1 stop
CLT7:48 pmCharlotte Douglas
Apr 1
CLT2:47 pmCharlotte Douglas
20h 28m
1 stop
MEM10:15 amMemphis
$220
Spirit Airlines
Apr 16
MEM11:14 amMemphis
6h 09m
1 stop
CLT6:23 pmCharlotte Douglas
Apr 19
CLT6:30 amCharlotte Douglas
4h 49m
1 stop
MEM10:19 amMemphis
$223

Southwest flights from Mississippi to South Carolina

Our best Southwest deals on Mississippi to South Carolina flight tickets
Southwest
Mar 5
MEM5:05 pmMemphis
4h 45m
1 stop
CLT10:50 pmCharlotte Douglas
Mar 16
CLT7:20 pmCharlotte Douglas
5h 00m
1 stop
MEM11:20 pmMemphis
$201
Southwest
Mar 5
MEM7:45 amMemphis
6h 50m
2 stops
CLT3:35 pmCharlotte Douglas
Mar 16
CLT6:10 amCharlotte Douglas
3h 30m
1 stop
MEM8:40 amMemphis
$206
Southwest
Feb 23
MEM7:05 amMemphis
9h 35m
2 stops
CLT5:40 pmCharlotte Douglas
Feb 26
CLT1:00 pmCharlotte Douglas
4h 50m
1 stop
MEM4:50 pmMemphis
$210

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Tue 3/17

11:14 am-8:03 am

1 stop19h 49m

Charlotte Douglas

Mon 3/23

9:28 pm-10:15 am

1 stop13h 47m

$171

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Wed 3/25

11:14 am-8:03 am

1 stop19h 49m

Charlotte Douglas

Wed 4/1

10:55 am-5:09 pm

2 stops31h 14m

$186

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Tue 3/10

11:15 am-8:03 am

1 stop19h 48m

Charlotte Douglas

Wed 3/18

1:59 pm-6:20 pm

2 stops29h 21m

$188

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 3/5

5:05 pm-10:50 pm

1 stop4h 45m

Charlotte Douglas

Mon 3/16

7:20 pm-11:20 pm

1 stop5h 00m

$201

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sun 3/29

4:52 pm-9:59 pm

1 stop4h 07m

Charleston

Thu 4/2

12:57 pm-4:12 pm

1 stop4h 15m

$225

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Tue 2/24

1:30 pm-7:03 pm

1 stop4h 33m

Charleston

Sat 2/28

3:45 pm-8:59 pm

1 stop6h 14m

$279

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Tue 2/24

5:00 am-5:20 pm

2 stops11h 20m

Charleston

Sat 2/28

3:45 pm-8:59 pm

1 stop6h 14m

$284

MemphisSavannah

MEM - SAV

MEMSAV

Memphis

Thu 4/30

12:30 pm-9:20 pm

1 stop7h 50m

Savannah/Hilton Head

Tue 5/5

6:40 am-9:05 am

1 stop3h 25m

$309

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Thu 3/26

7:05 pm-12:16 am

1 stop4h 11m

Charleston

Mon 3/30

6:09 pm-10:03 pm

1 stop4h 54m

$311

MemphisColumbia

MEM - CAE

MEMCAE

Memphis

Fri 3/20

12:07 pm-6:27 pm

1 stop5h 20m

Columbia Metropolitan

Sun 3/22

8:28 am-11:02 am

1 stop3h 34m

$343

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Mississippi to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Mississippi is in August. Flight prices, which tend to average around $271, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Mississippi during February instead. Flights to South Carolina in February, while not as cheap as those in August, still average around $303.

Cheap Mississippi to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to South Carolina

Fastest flight time

1h 53m

Direct flights

Every day

Airports in South Carolina

57 airports
The fastest flight from Mississippi to South Carolina takes 1h 53m
Direct flights go from Mississippi to South Carolina every day.
There are 57 airports in South Carolina. From Mississippi there are direct flights to Charlotte Douglas (CLT).
  • When did momondo last update prices for flights from Mississippi to South Carolina?

    Prices for flights from Mississippi to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Mississippi to South Carolina?

  • How old do you have to be to fly from Mississippi to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mississippi to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Mississippi to South Carolina

Compare and see reviews for airlines that fly from Mississippi to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $191Free CancellationRating
7.2
11,271 reviews
Search American Airlines flights
DeltaPriceFrom $193Free CancellationRating
7.9
8,180 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to South Carolina?

Finding the right flight to South Carolina from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from Mississippi to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Mississippi with this policy.

How can momondo help me find flights from Mississippi to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Mississippi.

I’m not ready to book a flight from Mississippi to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South Carolina trip

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1 adult
Fri 3/13
Fri 3/20

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Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo