Cheap flights from Mississippi to South Carolina from $94

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to South Carolina departing on 4/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Mississippi to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:54 pm - 6:14 pm
MEM
-
CLT
21h 20m
1 stop
Frontier Logo
7:14 pm - 7:09 pm
CLT
-
MEM
24h 55m
1 stop
$191Frontier
Wed, Jun 3 - Sun, Jun 7
Frontier Logo
7:54 pm - 4:25 pm
MEM
-
CLT
19h 31m
1 stop
Frontier Logo
7:14 pm - 7:09 pm
CLT
-
MEM
24h 55m
1 stop
$192Frontier
Mon, May 18 - Thu, May 21
Multiple Airlines Logo
6:45 pm - 8:02 pm
MEM
-
CLT
24h 17m
1 stop
Multiple Airlines Logo
9:07 pm - 5:49 pm
CLT
-
MEM
21h 42m
1 stop
$202Multiple Airlines
Sun, May 3 - Thu, May 7
Multiple Airlines Logo
6:45 pm - 9:10 am
MEM
-
CLT
13h 25m
1 stop
Multiple Airlines Logo
9:07 pm - 5:49 pm
CLT
-
MEM
21h 42m
1 stop
$208Multiple Airlines
Thu, Apr 30 - Thu, May 7
Multiple Airlines Logo
4:36 pm - 5:35 pm
MEM
-
CLT
23h 59m
1 stop
Multiple Airlines Logo
11:12 am - 3:40 pm
CLT
-
MEM
5h 28m
1 stop
$209Multiple Airlines
Thu, Apr 30 - Sun, May 3
Allegiant Air Logo
6:45 pm - 4:53 pm
MEM
-
GSP
21h 08m
1 stop
Allegiant Air Logo
10:23 am - 7:15 am
GSP
-
MEM
21h 52m
1 stop
$271Allegiant Air
Thu, Apr 23 - Sun, Apr 26
Delta Logo
5:54 pm - 12:36 am
MEM
-
CHS
5h 42m
1 stop
Delta Logo
5:10 am - 7:47 am
CHS
-
MEM
3h 37m
1 stop
$273Delta
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
3:58 pm - 9:46 pm
MEM
-
CHS
4h 48m
1 stop
American Airlines Logo
11:14 am - 5:10 pm
CHS
-
MEM
6h 56m
1 stop
$277American Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
7:01 pm - 11:57 pm
MEM
-
GSP
3h 56m
1 stop
American Airlines Logo
5:20 am - 8:18 am
GSP
-
MEM
3h 58m
1 stop
$302American Airlines
Wed, May 13 - Fri, May 15
Delta Logo
6:00 am - 11:20 am
BTR
-
CHS
4h 20m
1 stop
Delta Logo
4:35 pm - 9:58 pm
CHS
-
BTR
6h 23m
1 stop
$334Delta
Wed, Apr 15 - Sat, Apr 18

American Airlines flights from Mississippi to South Carolina

Our best American Airlines deals on Mississippi to South Carolina flight tickets
American Airlines
May 13
MEM5:05 amMemphis
4h 14m
1 stop
GSP10:19 amGreenville
May 15
GSP6:05 pmGreenville
6h 42m
1 stop
MEM11:47 pmMemphis
$326
American Airlines
May 4
MEM5:00 amMemphis
4h 19m
1 stop
GSP10:19 amGreenville
May 10
GSP5:20 amGreenville
3h 58m
1 stop
MEM8:18 amMemphis
$328
American Airlines
Apr 21
MEM3:58 pmMemphis
5h 38m
1 stop
CHS10:36 pmCharleston
Apr 27
CHS8:21 pmCharleston
4h 26m
1 stop
MEM11:47 pmMemphis
$335

Spirit Airlines flights from Mississippi to South Carolina

Our best Spirit Airlines deals on Mississippi to South Carolina flight tickets
Spirit Airlines
May 2
MEM5:09 pmMemphis
14h 00m
1 stop
CLT8:09 amCharlotte Douglas
May 3
CLT11:12 amCharlotte Douglas
5h 28m
1 stop
MEM3:40 pmMemphis
$237
Spirit Airlines
Apr 30
MEM4:43 pmMemphis
14h 26m
1 stop
CLT8:09 amCharlotte Douglas
May 3
CLT11:12 amCharlotte Douglas
5h 28m
1 stop
MEM3:40 pmMemphis
$238
Spirit Airlines
Apr 30
MEM4:43 pmMemphis
15h 27m
2 stops
CLT9:10 amCharlotte Douglas
May 3
CLT11:12 amCharlotte Douglas
5h 28m
1 stop
MEM3:40 pmMemphis
$265

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Wed 6/3

7:54 pm-6:14 pm

1 stop21h 20m

Charlotte Douglas

Sun 6/7

7:14 pm-7:09 pm

1 stop24h 55m

$191

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Mon 5/18

7:54 pm-4:25 pm

1 stop19h 31m

Charlotte Douglas

Thu 5/21

7:14 pm-7:09 pm

1 stop24h 55m

$192

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sun 5/3

6:45 pm-8:02 pm

1 stop24h 17m

Charlotte Douglas

Thu 5/7

9:07 pm-5:49 pm

1 stop21h 42m

$202

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 4/30

6:45 pm-9:10 am

1 stop13h 25m

Charlotte Douglas

Thu 5/7

9:07 pm-5:49 pm

1 stop21h 42m

$208

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 4/30

4:36 pm-5:35 pm

1 stop23h 59m

Charlotte Douglas

Sun 5/3

11:12 am-3:40 pm

1 stop5h 28m

$209

MemphisGreenville

MEM - GSP

MEMGSP

Memphis

Thu 4/23

6:45 pm-4:53 pm

1 stop21h 08m

Greenville

Sun 4/26

10:23 am-7:15 am

1 stop21h 52m

$271

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Tue 6/16

5:54 pm-12:36 am

1 stop5h 42m

Charleston

Tue 6/23

5:10 am-7:47 am

1 stop3h 37m

$273

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Tue 4/21

3:58 pm-9:46 pm

1 stop4h 48m

Charleston

Sat 4/25

11:14 am-5:10 pm

1 stop6h 56m

$277
Quickest round-trip

MemphisGreenville

MEM - GSP

MEMGSP

Memphis

Wed 5/13

7:01 pm-11:57 pm

1 stop3h 56m

Greenville

Fri 5/15

5:20 am-8:18 am

1 stop3h 58m

$302

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Wed 4/15

6:00 am-11:20 am

1 stop4h 20m

Charleston

Sat 4/18

4:35 pm-9:58 pm

1 stop6h 23m

$334

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to South Carolina from

How to get the cheapest flight ticket from Mississippi to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Mississippi is in August. Flight prices, which tend to average around $271, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Mississippi during February instead. Flights to South Carolina in February, while not as cheap as those in August, still average around $303.

Cheap Mississippi to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to South Carolina

Fastest flight time

1h 51m

Direct flights

Every day

Airports in South Carolina

57 airports
The fastest flight from Mississippi to South Carolina takes 1h 51m
Direct flights go from Mississippi to South Carolina every day.
There are 57 airports in South Carolina. From Mississippi there are direct flights to Charlotte Douglas (CLT).
  • When did momondo last update prices for flights from Mississippi to South Carolina?

    Prices for flights from Mississippi to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Mississippi to South Carolina?

  • How old do you have to be to fly from Mississippi to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mississippi to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Mississippi to South Carolina

Compare and see reviews for airlines that fly from Mississippi to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $191Free CancellationRating
7.1
11,544 reviews
Search American Airlines flights
DeltaPriceFrom $193Free CancellationRating
7.9
8,368 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to South Carolina?

Finding the right flight to South Carolina from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from Mississippi to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Mississippi with this policy.

How can momondo help me find flights from Mississippi to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Mississippi.

I’m not ready to book a flight from Mississippi to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 5/1
Fri 5/8

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo