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Cheap flights from Mexico City to Des Moines from $246

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Des Moines departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:15 am - 7:14 pm
MEX
-
DSM
33h 59m
2 stops
Multiple Airlines Logo
10:11 pm - 9:45 pm
DSM
-
MEX
24h 34m
1 stop
$547Multiple Airlines
Sun, Apr 5 - Fri, Apr 10
Frontier Logo
8:40 am - 1:31 pm
MEX
-
DSM
27h 51m
1 stop
Frontier Logo
2:16 pm - 5:30 pm
DSM
-
MEX
28h 14m
1 stop
$548Frontier
Sun, May 24 - Fri, Aug 14
Multiple Airlines Logo
8:40 am - 1:09 pm
MEX
-
DSM
27h 29m
1 stop
Multiple Airlines Logo
2:59 pm - 7:45 pm
DSM
-
MEX
29h 46m
2 stops
$551Multiple Airlines
Thu, Apr 16 - Thu, Apr 23
Multiple Airlines Logo
11:05 am - 9:33 am
MEX
-
DSM
21h 28m
1 stop
Multiple Airlines Logo
11:00 am - 8:05 pm
DSM
-
MEX
34h 05m
2 stops
$562Multiple Airlines
Thu, Apr 9 - Sat, May 9
American Airlines Logo
7:00 am - 11:16 pm
MEX
-
DSM
15h 16m
1 stop
American Airlines Logo
5:19 am - 2:19 pm
DSM
-
MEX
10h 00m
1 stop
$569American Airlines
Tue, May 5 - Tue, May 12
Aeromexico Logo
9:00 pm - 5:45 pm
MEX
-
DSM
19h 45m
2 stops
Aeromexico Logo
11:57 am - 7:00 pm
DSM
-
MEX
8h 03m
1 stop
$573Aeromexico
Tue, May 5 - Tue, May 12
Delta Logo
8:40 am - 8:45 pm
MEX
-
DSM
11h 05m
2 stops
Delta Logo
5:45 am - 1:55 pm
DSM
-
MEX
9h 10m
1 stop
$577Delta
Thu, Aug 27 - Sun, Aug 30
United Airlines Logo
8:05 am - 4:15 pm
MEX
-
DSM
7h 10m
1 stop
United Airlines Logo
5:17 pm - 8:35 am
DSM
-
MEX
16h 18m
2 stops
$581United Airlines
Thu, Apr 16 - Sun, Apr 19
Frontier Logo
7:55 pm - 1:31 pm
MEX
-
DSM
16h 36m
2 stops
Frontier Logo
2:16 pm - 4:50 am
DSM
-
MEX
15h 34m
2 stops
$583Frontier
Sun, May 24 - Fri, Aug 14
Delta Logo
8:40 am - 9:17 pm
MEX
-
DSM
11h 37m
2 stops
Delta Logo
10:55 am - 7:00 pm
DSM
-
MEX
9h 05m
2 stops
$585Delta
Thu, Aug 27 - Sun, Aug 30

United Airlines flights from Mexico City to Des Moines

Our best United Airlines deals on Mexico City to Des Moines flight tickets
United Airlines
Apr 16
MEX8:05 amMexico City Benito Juarez
7h 10m
1 stop
DSM4:15 pmDes Moines
Apr 19
DSM5:17 pmDes Moines
16h 18m
2 stops
MEX8:35 amMexico City Benito Juarez
$581
United Airlines
Apr 16
MEX8:05 amMexico City Benito Juarez
7h 10m
1 stop
DSM4:15 pmDes Moines
Apr 19
DSM8:20 amDes Moines
10h 30m
1 stop
MEX5:50 pmMexico City Benito Juarez
$602
United Airlines
May 24
MEX4:40 amMexico City Benito Juarez
10h 35m
2 stops
DSM4:15 pmDes Moines
Aug 14
DSM6:15 amDes Moines
8h 00m
1 stop
MEX1:15 pmMexico City Benito Juarez
$605

Delta flights from Mexico City to Des Moines

Our best Delta deals on Mexico City to Des Moines flight tickets
Delta
Aug 27
MEX8:40 amMexico City Benito Juarez
11h 05m
2 stops
DSM8:45 pmDes Moines
Aug 30
DSM5:45 amDes Moines
9h 10m
1 stop
MEX1:55 pmMexico City Benito Juarez
$577
Delta
Aug 27
MEX8:40 amMexico City Benito Juarez
11h 37m
2 stops
DSM9:17 pmDes Moines
Aug 30
DSM10:55 amDes Moines
9h 05m
2 stops
MEX7:00 pmMexico City Benito Juarez
$585
Delta
Aug 28
MEX9:05 amMexico City Benito Juarez
10h 40m
2 stops
DSM8:45 pmDes Moines
Aug 30
DSM10:55 amDes Moines
9h 05m
2 stops
MEX7:00 pmMexico City Benito Juarez
$609

momondo Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 4/5

8:15 am-7:14 pm

2 stops33h 59m

Des Moines

Fri 4/10

10:11 pm-9:45 pm

1 stop24h 34m

$547

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

8:40 am-1:31 pm

1 stop27h 51m

Des Moines

Fri 8/14

2:16 pm-5:30 pm

1 stop28h 14m

$548

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 4/16

8:40 am-1:09 pm

1 stop27h 29m

Des Moines

Thu 4/23

2:59 pm-7:45 pm

2 stops29h 46m

$551

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 4/9

11:05 am-9:33 am

1 stop21h 28m

Des Moines

Sat 5/9

11:00 am-8:05 pm

2 stops34h 05m

$562

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 5/5

7:00 am-11:16 pm

1 stop15h 16m

Des Moines

Tue 5/12

5:19 am-2:19 pm

1 stop10h 00m

$569

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 5/5

9:00 pm-5:45 pm

2 stops19h 45m

Des Moines

Tue 5/12

11:57 am-7:00 pm

1 stop8h 03m

$573
Quickest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 8/27

8:40 am-8:45 pm

2 stops11h 05m

Des Moines

Sun 8/30

5:45 am-1:55 pm

1 stop9h 10m

$577

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 4/16

8:05 am-4:15 pm

1 stop7h 10m

Des Moines

Sun 4/19

5:17 pm-8:35 am

2 stops16h 18m

$581

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

7:55 pm-1:31 pm

2 stops16h 36m

Des Moines

Fri 8/14

2:16 pm-4:50 am

2 stops15h 34m

$583

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 8/27

8:40 am-9:17 pm

2 stops11h 37m

Des Moines

Sun 8/30

10:55 am-7:00 pm

2 stops9h 05m

$585

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Mexico City to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then September is your next best option. Flight prices from Mexico City to Des Moines during September average around $486.

Can stopping save me money on Mexico City to Des Moines flights?

You could potentially save up to 27% on your flight if you consider stops on a Mexico City to Des Moines flight.

When to book flights from Mexico City to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Des Moines (MEX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Des Moines

Fastest flight time

8h 40m

Direct flights

None
The fastest flight from Mexico City to Des Moines takes 8h 40m
There are no direct flights from Mexico City to Des Moines. There are no popular flight routes from Mexico City to Des Moines.
Search flight deals

  • How far is Mexico City Benito Juarez to Des Moines by plane?

    There are 1564.5 mi between Mexico City Benito Juarez and Des Moines. 8h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Des Moines Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Des Moines Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mexico City Benito Juarez Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Mexico City to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Mexico City to Des Moines with flexible booking policies on momondo?

All flight searches from Mexico City to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mexico City to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Mexico City.

I’m not ready to book a flight from Mexico City to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Mexico City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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