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Cheap flights from Melbourne, Florida to Des Moines from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Melbourne, Florida to Des Moines departing on 5/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Melbourne, Florida to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:55 am - 10:14 am
MLB
-
DSM
5h 19m
1 stop
Delta Logo
2:15 pm - 10:47 pm
DSM
-
MLB
7h 32m
1 stop
$403Delta
Sat, Aug 15 - Wed, Aug 26
Delta Logo
5:46 am - 11:08 am
MLB
-
DSM
6h 22m
1 stop
Delta Logo
4:00 pm - 11:46 pm
DSM
-
MLB
6h 46m
1 stop
$435Delta
Fri, May 8 - Sat, May 9
Delta Logo
6:00 am - 11:05 am
MLB
-
DSM
6h 05m
1 stop
Delta Logo
2:44 pm - 9:39 pm
DSM
-
MLB
5h 55m
1 stop
$437Delta
Sat, Apr 18 - Sat, Apr 25
American Airlines Logo
5:35 pm - 10:18 pm
MLB
-
DSM
5h 43m
1 stop
American Airlines Logo
12:00 pm - 12:14 am
DSM
-
MLB
11h 14m
2 stops
$440American Airlines
Fri, May 8 - Sat, May 9
American Airlines Logo
11:54 am - 11:59 pm
MLB
-
DSM
13h 05m
2 stops
American Airlines Logo
6:00 am - 5:05 pm
DSM
-
MLB
10h 05m
2 stops
$445American Airlines
Fri, May 8 - Sat, May 9
Delta Logo
5:55 am - 10:14 am
MLB
-
DSM
5h 19m
1 stop
Delta Logo
11:04 am - 6:02 pm
DSM
-
MLB
5h 58m
1 stop
$455Delta
Sun, Aug 16 - Sat, Aug 22
Delta Logo
6:00 am - 11:05 am
MLB
-
DSM
6h 05m
1 stop
Delta Logo
5:45 am - 2:19 pm
DSM
-
MLB
7h 34m
1 stop
$461Delta
Sat, Apr 18 - Thu, Apr 23
Delta Logo
6:00 am - 11:05 am
MLB
-
DSM
6h 05m
1 stop
Delta Logo
6:31 pm - 11:50 pm
DSM
-
MLB
4h 19m
1 stop
$462Delta
Sat, Apr 18 - Fri, Apr 24
Delta Logo
5:55 am - 10:14 am
MLB
-
DSM
5h 19m
1 stop
Delta Logo
2:15 pm - 10:47 pm
DSM
-
MLB
7h 32m
1 stop
$467Delta
Thu, Aug 13 - Mon, Aug 24
Delta Logo
6:35 pm - 9:17 pm
MLB
-
DSM
27h 42m
2 stops
Delta Logo
2:15 pm - 10:47 pm
DSM
-
MLB
7h 32m
1 stop
$470Delta
Fri, Aug 14 - Wed, Aug 26

Delta flights from Melbourne, Florida to Des Moines

Our best Delta deals on Melbourne, Florida to Des Moines flight tickets
Delta
Aug 15
MLB5:55 amMelbourne
5h 19m
1 stop
DSM10:14 amDes Moines
Aug 26
DSM2:15 pmDes Moines
7h 32m
1 stop
MLB10:47 pmMelbourne
$403
Delta
May 8
MLB5:46 amMelbourne
6h 22m
1 stop
DSM11:08 amDes Moines
May 9
DSM4:00 pmDes Moines
6h 46m
1 stop
MLB11:46 pmMelbourne
$435
Delta
Apr 18
MLB6:00 amMelbourne
6h 05m
1 stop
DSM11:05 amDes Moines
Apr 25
DSM2:44 pmDes Moines
5h 55m
1 stop
MLB9:39 pmMelbourne
$437

American Airlines flights from Melbourne, Florida to Des Moines

Our best American Airlines deals on Melbourne, Florida to Des Moines flight tickets
American Airlines
May 8
MLB5:35 pmMelbourne
5h 43m
1 stop
DSM10:18 pmDes Moines
May 9
DSM12:00 pmDes Moines
11h 14m
2 stops
MLB12:14 amMelbourne
$440
American Airlines
May 8
MLB11:54 amMelbourne
13h 05m
2 stops
DSM11:59 pmDes Moines
May 9
DSM6:00 amDes Moines
10h 05m
2 stops
MLB5:05 pmMelbourne
$445
American Airlines
May 22
MLB7:07 pmMelbourne
6h 10m
1 stop
DSM12:17 amDes Moines
May 24
DSM1:48 pmDes Moines
9h 04m
2 stops
MLB11:52 pmMelbourne
$472

momondo Fare Finder

 
Customize your flight search to find flights from Melbourne, Florida to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Melbourne, Florida to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Sat 8/15

5:55 am-10:14 am

1 stop5h 19m

Des Moines

Wed 8/26

2:15 pm-10:47 pm

1 stop7h 32m

$403

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 5/8

5:46 am-11:08 am

1 stop6h 22m

Des Moines

Sat 5/9

4:00 pm-11:46 pm

1 stop6h 46m

$435

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Sat 4/18

6:00 am-11:05 am

1 stop6h 05m

Des Moines

Sat 4/25

2:44 pm-9:39 pm

1 stop5h 55m

$437

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 5/8

5:35 pm-10:18 pm

1 stop5h 43m

Des Moines

Sat 5/9

12:00 pm-12:14 am

2 stops11h 14m

$440

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 5/8

11:54 am-11:59 pm

2 stops13h 05m

Des Moines

Sat 5/9

6:00 am-5:05 pm

2 stops10h 05m

$445

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Sun 8/16

5:55 am-10:14 am

1 stop5h 19m

Des Moines

Sat 8/22

11:04 am-6:02 pm

1 stop5h 58m

$455

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Sat 4/18

6:00 am-11:05 am

1 stop6h 05m

Des Moines

Thu 4/23

5:45 am-2:19 pm

1 stop7h 34m

$461
Quickest round-trip

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Sat 4/18

6:00 am-11:05 am

1 stop6h 05m

Des Moines

Fri 4/24

6:31 pm-11:50 pm

1 stop4h 19m

$462

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Thu 8/13

5:55 am-10:14 am

1 stop5h 19m

Des Moines

Mon 8/24

2:15 pm-10:47 pm

1 stop7h 32m

$467

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 8/14

6:35 pm-9:17 pm

2 stops27h 42m

Des Moines

Wed 8/26

2:15 pm-10:47 pm

1 stop7h 32m

$470

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Melbourne, Florida to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Melbourne, Florida to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $129. Flights from Melbourne, Florida to Des Moines on a Monday will generally be more expensive and average around $338. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Melbourne, Florida to Des Moines in the evening for as low as $158. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $227. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Melbourne, Florida to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Melbourne, Florida to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Melbourne, Florida to Des Moines (MLB to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Melbourne, Florida to Des Moines

Fastest flight time

5h 19m

Direct flights

None
The fastest flight from Melbourne, Florida to Des Moines takes 5h 19m
There are no direct flights from Melbourne, Florida to Des Moines. There are no popular flight routes from Melbourne, Florida to Des Moines.
Search flight deals

  • How far is Melbourne to Des Moines by plane?

    There are 1186.0 mi between Melbourne and Des Moines. A reasonable flight in good conditions will take 5h 19m.

  • When did momondo last update prices for flights from Melbourne Airport to Des Moines Airport?

    Prices for flights from Melbourne Airport to Des Moines Airport refresh daily.

  • How old do you have to be to fly from Melbourne Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Melbourne Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Melbourne to Des Moines?

Finding the right flight to Des Moines from Melbourne is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Melbourne to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Melbourne on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Melbourne to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Melbourne. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Melbourne to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Melbourne to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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