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Cheap flights from McAllen to Knoxville from $338

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from McAllen to Knoxville departing on 6/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from McAllen to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:37 pm - 11:52 pm
MFE
-
TYS
10h 15m
2 stops
Delta Logo
6:00 am - 11:57 am
TYS
-
MFE
6h 57m
2 stops
$365Delta
Mon, Aug 3 - Sat, Aug 29
Allegiant Air Logo
6:21 pm - 10:24 pm
MFE
-
TYS
27h 03m
1 stop
Allegiant Air Logo
6:54 pm - 7:53 am
TYS
-
MFE
13h 59m
1 stop
$388Allegiant Air
Wed, Jul 1 - Sun, Aug 2
American Airlines Logo
1:43 pm - 7:30 pm
MFE
-
TYS
4h 47m
1 stop
American Airlines Logo
6:03 am - 10:26 am
TYS
-
MFE
5h 23m
1 stop
$389American Airlines
Mon, Aug 3 - Sat, Aug 29
American Airlines Logo
7:00 am - 1:02 pm
MFE
-
TYS
5h 02m
1 stop
American Airlines Logo
5:37 am - 9:57 am
TYS
-
MFE
5h 20m
1 stop
$442American Airlines
Tue, Jun 30 - Wed, Jul 8
American Airlines Logo
5:00 am - 11:13 am
MFE
-
TYS
5h 13m
1 stop
American Airlines Logo
1:56 pm - 10:02 pm
TYS
-
MFE
9h 06m
2 stops
$451American Airlines
Mon, Aug 3 - Sat, Aug 29
American Airlines Logo
5:00 am - 11:13 am
MFE
-
TYS
5h 13m
1 stop
American Airlines Logo
5:37 am - 9:57 am
TYS
-
MFE
5h 20m
1 stop
$464American Airlines
Tue, Jun 30 - Wed, Jul 8
Delta Logo
5:20 am - 2:48 pm
MFE
-
TYS
8h 28m
2 stops
Delta Logo
5:40 am - 11:57 am
TYS
-
MFE
7h 17m
2 stops
$495Delta
Sun, Jul 26 - Mon, Aug 3
Allegiant Air Logo
6:21 pm - 12:46 pm
MFE
-
TYS
41h 25m
2 stops
Allegiant Air Logo
6:54 pm - 7:53 am
TYS
-
MFE
13h 59m
1 stop
$517Allegiant Air
Wed, Jul 1 - Sun, Aug 2
Allegiant Air Logo
9:59 pm - 1:57 pm
MFE
-
TYS
14h 58m
1 stop
Allegiant Air Logo
2:47 pm - 4:04 pm
TYS
-
MFE
26h 17m
1 stop
$523Allegiant Air
Sun, Jul 26 - Mon, Aug 3
Multiple Airlines Logo
9:59 pm - 1:57 pm
MFE
-
TYS
14h 58m
1 stop
Multiple Airlines Logo
7:20 pm - 4:04 pm
TYS
-
MFE
45h 44m
2 stops
$541Multiple Airlines
Sun, Jul 26 - Mon, Aug 3

American Airlines flights from McAllen to Knoxville

Our best American Airlines deals on McAllen to Knoxville flight tickets
American Airlines
Aug 3
MFE1:43 pmMcAllen Miller Intl
4h 47m
1 stop
TYS7:30 pmKnoxville McGhee Tyson
Aug 29
TYS6:03 amKnoxville McGhee Tyson
5h 23m
1 stop
MFE10:26 amMcAllen Miller Intl
$389
American Airlines
Jun 10
MFE7:00 amMcAllen Miller Intl
5h 02m
1 stop
TYS1:02 pmKnoxville McGhee Tyson
Jun 17
TYS5:33 pmKnoxville McGhee Tyson
5h 26m
1 stop
MFE9:59 pmMcAllen Miller Intl
$416
American Airlines
Jun 30
MFE7:00 amMcAllen Miller Intl
5h 02m
1 stop
TYS1:02 pmKnoxville McGhee Tyson
Jul 8
TYS5:37 amKnoxville McGhee Tyson
5h 20m
1 stop
MFE9:57 amMcAllen Miller Intl
$442

Delta flights from McAllen to Knoxville

Our best Delta deals on McAllen to Knoxville flight tickets
Delta
Aug 3
MFE12:37 pmMcAllen Miller Intl
10h 15m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
Aug 29
TYS6:00 amKnoxville McGhee Tyson
6h 57m
2 stops
MFE11:57 amMcAllen Miller Intl
$365
Delta
Jul 26
MFE5:20 amMcAllen Miller Intl
8h 28m
2 stops
TYS2:48 pmKnoxville McGhee Tyson
Aug 3
TYS5:40 amKnoxville McGhee Tyson
7h 17m
2 stops
MFE11:57 amMcAllen Miller Intl
$495
Delta
Jun 10
MFE5:20 amMcAllen Miller Intl
8h 59m
2 stops
TYS3:19 pmKnoxville McGhee Tyson
Jun 17
TYS5:40 amKnoxville McGhee Tyson
11h 43m
2 stops
MFE4:23 pmMcAllen Miller Intl
$519

momondo Fare Finder

 
Customize your flight search to find flights from McAllen to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from McAllen to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Mon 8/3

12:37 pm-11:52 pm

2 stops10h 15m

Knoxville McGhee Tyson

Sat 8/29

6:00 am-11:57 am

2 stops6h 57m

$365

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Wed 7/1

6:21 pm-10:24 pm

1 stop27h 03m

Knoxville McGhee Tyson

Sun 8/2

6:54 pm-7:53 am

1 stop13h 59m

$388
Quickest round-trip

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Mon 8/3

1:43 pm-7:30 pm

1 stop4h 47m

Knoxville McGhee Tyson

Sat 8/29

6:03 am-10:26 am

1 stop5h 23m

$389

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Tue 6/30

7:00 am-1:02 pm

1 stop5h 02m

Knoxville McGhee Tyson

Wed 7/8

5:37 am-9:57 am

1 stop5h 20m

$442

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Mon 8/3

5:00 am-11:13 am

1 stop5h 13m

Knoxville McGhee Tyson

Sat 8/29

1:56 pm-10:02 pm

2 stops9h 06m

$451

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Tue 6/30

5:00 am-11:13 am

1 stop5h 13m

Knoxville McGhee Tyson

Wed 7/8

5:37 am-9:57 am

1 stop5h 20m

$464

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Sun 7/26

5:20 am-2:48 pm

2 stops8h 28m

Knoxville McGhee Tyson

Mon 8/3

5:40 am-11:57 am

2 stops7h 17m

$495

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Wed 7/1

6:21 pm-12:46 pm

2 stops41h 25m

Knoxville McGhee Tyson

Sun 8/2

6:54 pm-7:53 am

1 stop13h 59m

$517

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Sun 7/26

9:59 pm-1:57 pm

1 stop14h 58m

Knoxville McGhee Tyson

Mon 8/3

2:47 pm-4:04 pm

1 stop26h 17m

$523

McAllenKnoxville

MFE - TYS

MFETYS

McAllen Miller Intl

Sun 7/26

9:59 pm-1:57 pm

1 stop14h 58m

Knoxville McGhee Tyson

Mon 8/3

7:20 pm-4:04 pm

2 stops45h 44m

$541

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from McAllen to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between McAllen and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of October is, on average, the cheapest month to fly to Knoxville from McAllen, with most prices found around $0. If you aren’t able to travel during the month of October, then book flights to Knoxville from McAllen during February instead. Flights to Knoxville in February, while not as cheap as those in October, still average around $0.

Can stopping save me money on McAllen to Knoxville flights?

You could potentially save up to 27% on your flight if you consider stops on a McAllen to Knoxville flight.

When to book flights from McAllen to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from McAllen to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap McAllen to Knoxville (MFE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from McAllen to Knoxville

Fastest flight time

8h 29m

Direct flights

None
The fastest flight from McAllen to Knoxville takes 8h 29m
There are no direct flights from McAllen to Knoxville. There are no popular flight routes from McAllen to Knoxville.
Search flight deals

Frequently asked questions about flying from McAllen to Knoxville

  • How far is McAllen Miller Intl to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 1079.4 mi away from McAllen Miller Intl. Typically, this will take 8h 29m by plane in normal conditions.

  • When did momondo last update prices for flights from McAllen Miller Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from McAllen Miller Intl Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from McAllen Miller Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from McAllen Miller Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from McAllen Miller Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from McAllen to Knoxville?

Best airlines flying from McAllen to Knoxville

Compare and see reviews for airlines that fly from McAllen to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $324Free CancellationRating
7.1
11,648 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Maryville
Crossville
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from McAllen to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from McAllen.

Can I find flights from McAllen to Knoxville with flexible booking policies on momondo?

All flight searches from McAllen to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from McAllen to Knoxville?

Once all potential McAllen to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from McAllen to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of McAllen to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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