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Cheap flights from Massachusetts to South America from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to South America departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Massachusetts to South America

Cheap round-trip flights

Spirit Airlines Logo
3:00 pm - 12:28 amBOS-MDE
10h 28m1 stop
Spirit Airlines Logo
1:24 am - 11:13 amMDE-BOS
8h 49m1 stop
$211Spirit Airlines
Find Deal
Sat, Sep 6 - Mon, Sep 8
Spirit Airlines Logo
3:00 pm - 12:28 amBOS-MDE
10h 28m1 stop
Spirit Airlines Logo
1:24 am - 11:13 amMDE-BOS
8h 49m1 stop
$235Spirit Airlines
Find Deal
Tue, Sep 9 - Mon, Sep 22
Logo
6:10 am - 11:17 pmBOS-MDE
18h 07m2 stops
Logo
1:24 am - 11:13 amMDE-BOS
8h 49m1 stop
$288
Find Deal
Sat, Sep 6 - Mon, Sep 8
Logo
6:10 am - 9:57 pmBOS-MDE
16h 47m2 stops
Logo
1:24 am - 11:13 amMDE-BOS
8h 49m1 stop
$315
Find Deal
Tue, Sep 9 - Wed, Sep 10
Avianca Logo
7:55 am - 12:50 amBOS-LIM
16h 55m1 stop
Avianca Logo
6:30 am - 6:35 amLIM-BOS
24h 05m1 stop
$386Avianca
Find Deal
Thu, Nov 6 - Mon, Nov 10
Avianca Logo
7:55 am - 8:55 pmBOS-LIM
13h 00m1 stop
Avianca Logo
11:45 am - 6:35 amLIM-BOS
18h 50m1 stop
$419Avianca
Find Deal
Thu, Nov 6 - Mon, Nov 17
LATAM Airlines Logo
6:35 pm - 5:00 amBOS-LIM
11h 25m1 stop
LATAM Airlines Logo
12:00 pm - 1:18 amLIM-BOS
12h 18m1 stop
$424LATAM Airlines
Find Deal
Fri, Sep 26 - Tue, Sep 30
LATAM Airlines Logo
6:35 pm - 5:00 amBOS-LIM
11h 25m1 stop
LATAM Airlines Logo
12:15 am - 2:59 pmLIM-BOS
13h 44m1 stop
$431LATAM Airlines
Find Deal
Fri, Sep 26 - Mon, Sep 29
Delta Logo
9:05 am - 5:00 amBOS-LIM
20h 55m1 stop
Delta Logo
8:50 am - 1:18 amLIM-BOS
15h 28m2 stops
$435Delta
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Fri, Sep 26 - Mon, Sep 29
Delta Logo
6:35 pm - 6:25 amBOS-LIM
12h 50m2 stops
Delta Logo
12:15 am - 2:59 pmLIM-BOS
13h 44m1 stop
$439Delta
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Thu, Sep 25 - Sun, Sep 28

GOL flights from Massachusetts to South America

Our best GOL deals on Massachusetts to South America flight tickets
GOL
Sep 9
BOS9:00 amBoston Logan Intl
16h 10m
1 stop
GRU2:10 amSao Paulo Guarulhos Intl
Sep 19
GRU4:10 amSao Paulo Guarulhos Intl
28h 05m
1 stop
BOS7:15 amBoston Logan Intl
$495
Find similar
GOL
Sep 23
BOS9:00 amBoston Logan Intl
33h 00m
2 stops
VCP7:00 pmSao Paulo Viracopos
Oct 2
VCP7:40 pmSao Paulo Viracopos
36h 35m
2 stops
BOS7:15 amBoston Logan Intl
$507
Find similar
GOL
Jan 15
BOS7:55 amBoston Logan Intl
17h 15m
1 stop
GRU3:10 amSao Paulo Guarulhos Intl
Feb 3
GRU4:15 amSao Paulo Guarulhos Intl
28h 20m
1 stop
BOS6:35 amBoston Logan Intl
$508
Find similar

Copa Airlines flights from Massachusetts to South America

Our best Copa Airlines deals on Massachusetts to South America flight tickets
Copa Airlines
Aug 5
BOS4:05 pmBoston Logan Intl
17h 12m
1 stop
MDE8:17 amMedellín Jose Maria Cordova Intl
Aug 26
MDE12:46 pmMedellín Jose Maria Cordova Intl
8h 45m
1 stop
BOS10:31 pmBoston Logan Intl
$419
Find similar
Copa Airlines
Sep 18
BOS3:49 pmBoston Logan Intl
30h 31m
1 stop
CNF11:20 pmBelo Horizonte Tancredo Neves Intl
Sep 24
CNF12:20 amBelo Horizonte Tancredo Neves Intl
20h 02m
1 stop
BOS7:22 pmBoston Logan Intl
$463
Find similar
Copa Airlines
Sep 2
BOS8:41 amBoston Logan Intl
18h 09m
1 stop
GRU3:50 amSao Paulo Guarulhos Intl
Sep 9
GRU5:25 amSao Paulo Guarulhos Intl
14h 57m
1 stop
BOS7:22 pmBoston Logan Intl
$498
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2025.
Use the filters below to find and compare flights from Massachusetts to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sat 9/6

3:00 pm-12:28 am

1 stop10h 28m

Medellín Jose Maria Cordova Intl

Mon 9/8

1:24 am-11:13 am

1 stop8h 49m

$211

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Tue 9/9

3:00 pm-12:28 am

1 stop10h 28m

Medellín Jose Maria Cordova Intl

Mon 9/22

1:24 am-11:13 am

1 stop8h 49m

$235

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sat 9/6

6:10 am-11:17 pm

2 stops18h 07m

Medellín Jose Maria Cordova Intl

Mon 9/8

1:24 am-11:13 am

1 stop8h 49m

$288

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Tue 9/9

6:10 am-9:57 pm

2 stops16h 47m

Medellín Jose Maria Cordova Intl

Wed 9/10

1:24 am-11:13 am

1 stop8h 49m

$315

BostonLima

BOS - LIM

BOSLIM

Boston Logan Intl

Thu 11/6

7:55 am-12:50 am

1 stop16h 55m

Lima J Chavez Intl

Mon 11/10

6:30 am-6:35 am

1 stop24h 05m

$386

BostonLima

BOS - LIM

BOSLIM

Boston Logan Intl

Thu 11/6

7:55 am-8:55 pm

1 stop13h 00m

Lima J Chavez Intl

Mon 11/17

11:45 am-6:35 am

1 stop18h 50m

$419

BostonLima

BOS - LIM

BOSLIM

Boston Logan Intl

Fri 9/26

6:35 pm-5:00 am

1 stop11h 25m

Lima J Chavez Intl

Tue 9/30

12:00 pm-1:18 am

1 stop12h 18m

$424

BostonLima

BOS - LIM

BOSLIM

Boston Logan Intl

Fri 9/26

6:35 pm-5:00 am

1 stop11h 25m

Lima J Chavez Intl

Mon 9/29

12:15 am-2:59 pm

1 stop13h 44m

$431

BostonLima

BOS - LIM

BOSLIM

Boston Logan Intl

Fri 9/26

9:05 am-5:00 am

1 stop20h 55m

Lima J Chavez Intl

Mon 9/29

8:50 am-1:18 am

2 stops15h 28m

$435

BostonLima

BOS - LIM

BOSLIM

Boston Logan Intl

Thu 9/25

6:35 pm-6:25 am

2 stops12h 50m

Lima J Chavez Intl

Sun 9/28

12:15 am-2:59 pm

1 stop13h 44m

$439

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Massachusetts to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Massachusetts to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $479. If you aren’t able to travel during the month of November, then book flights to South America from Massachusetts during September instead. Flights to South America in September, while not as cheap as those in November, still average around $507.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Massachusetts to South America is on a Monday when prices can be found for as low as $531. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Massachusetts to South America for around $635.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Massachusetts to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $508. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $594 on average. Flights to South America from Massachusetts in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Massachusetts to South America flight route?

Fly from Boston Logan Intl to Bogotá El Dorado for the best Massachusetts - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $623 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Massachusetts for as low as $533 on momondo.

What cabin class options are available on Massachusetts to South America flights?

There are 4 cabin classes available to choose from on Massachusetts to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Massachusetts to South America flights?

You could potentially save up to 34% on your flight if you consider stops on a Massachusetts to South America flight.

Cheap Massachusetts to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to South America

Best Price Found

$86

Fastest flight time

8h 04m

Direct flights

Mon, Tue, Fri and Sun

Airports in South America

5 airports
The best one-way flight to South America from Massachusetts in the past 72 hours is $86. The best round-trip flight deal from Massachusetts to South America found on momondo in the last 72 hours is $211.
The fastest flight from Massachusetts to South America takes 8h 04m
Direct flights go from Massachusetts to South America on Monday, Tuesday, Friday and Sunday. Airlines offering direct flights are: Delta and LATAM Airlines.
There are 5 airports near South America: Lima J Chavez Intl (LIM), Buenos Aires Ministro Pistarini (EZE), Rio de Janeiro–Galeão Intl (GIG), Sao Paulo Guarulhos Intl (GRU), Medellín Jose Maria Cordova Intl (MDE)
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  • When did momondo last update prices for flights from Massachusetts to South America?

    Prices for flights from Massachusetts to South America refresh daily.

  • How many operators does momondo search for flights from Massachusetts to South America?

  • How old do you have to be to fly from Massachusetts to South America?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Massachusetts to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Massachusetts to South America?

Best airlines flying from Massachusetts to South America

Compare and see reviews for airlines that fly from Massachusetts to South America with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $234Free CancellationRating
7.4
8,912 reviews
Search United Airlines flights
Spirit AirlinesPriceFrom $248Free CancellationRating
6.3
8,053 reviews
Search Spirit Airlines flights
AviancaPriceFrom $286Free CancellationRating
6.7
2,394 reviews
Search Avianca flights
DeltaPriceFrom $303Free CancellationRating
8.0
7,987 reviews
Search Delta flights
LATAM AirlinesPriceFrom $311Free CancellationRating
7.5
1,830 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $311Free CancellationRating
7.5
1,500 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $326Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
GOLPriceFrom $343Free CancellationRating
7.3
1,091 reviews
Search GOL flights
JetBluePriceFrom $420Free CancellationRating
7.2
2,915 reviews
Search JetBlue flights
Air CanadaPriceFrom $588Free CancellationRating
7.1
9,879 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Massachusetts to South America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Massachusetts to South America with flexible booking policies on momondo?

momondo does allow users to show only those flights to South America from Massachusetts which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Massachusetts to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Massachusetts to South America.

I’m not ready to book a flight from Massachusetts to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Massachusetts are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $306
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Flights to Sao Paulofrom $348
Flights to Medellínfrom $155
Flights to Rio de Janeirofrom $429
Flights to Santiagofrom $379
Flights to Cartagenafrom $180
Flights to Quitofrom $321
Flights to Cuscofrom $418
Flights to Califrom $179
Flights to Guayaquilfrom $231