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Cheap flights from Massachusetts to South America from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to South America departing on 4/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:27 am - 2:13 pm
BOS
-
MDE
8h 46m
1 stop
Spirit Airlines Logo
2:15 pm - 10:01 pm
MDE
-
BOS
30h 46m
2 stops
$268Spirit Airlines
Tue, Mar 3 - Tue, Mar 10
Spirit Airlines Logo
3:43 pm - 1:55 pm
BOS
-
MDE
22h 12m
1 stop
Spirit Airlines Logo
3:15 pm - 11:57 pm
MDE
-
BOS
8h 42m
1 stop
$269Spirit Airlines
Sat, Feb 7 - Tue, Feb 10
Avianca Logo
4:50 pm - 2:05 am
BOS
-
MDE
10h 15m
1 stop
Avianca Logo
8:52 pm - 7:15 am
MDE
-
BOS
9h 23m
1 stop
$273Avianca
Mon, Apr 27 - Mon, May 11
Avianca Logo
8:55 am - 8:15 pm
BOS
-
MDE
12h 20m
1 stop
Avianca Logo
8:10 pm - 7:35 am
MDE
-
BOS
10h 25m
1 stop
$278Avianca
Thu, Mar 12 - Mon, Mar 16
Copa Airlines Logo
3:07 pm - 12:05 am
BOS
-
BOG
8h 58m
1 stop
Copa Airlines Logo
10:00 am - 10:10 pm
BOG
-
BOS
12h 10m
1 stop
$348Copa Airlines
Thu, Feb 26 - Mon, Mar 2
LATAM Airlines Logo
7:15 am - 6:40 pm
BOS
-
BOG
11h 25m
1 stop
LATAM Airlines Logo
9:00 am - 1:04 am
BOG
-
BOS
16h 04m
1 stop
$352LATAM Airlines
Thu, Feb 5 - Sun, Feb 8
Multiple Airlines Logo
5:49 pm - 5:40 am
BOS
-
BOG
12h 51m
2 stops
Multiple Airlines Logo
2:10 pm - 11:59 pm
BOG
-
BOS
8h 49m
1 stop
$353Multiple Airlines
Wed, Apr 1 - Thu, Apr 9
Multiple Airlines Logo
11:15 am - 9:10 pm
BOS
-
BOG
9h 55m
1 stop
Multiple Airlines Logo
3:06 pm - 3:27 pm
BOG
-
BOS
24h 21m
2 stops
$356Multiple Airlines
Wed, Feb 18 - Tue, Feb 24
Copa Airlines Logo
8:44 am - 12:10 am
BOS
-
GRU
14h 26m
1 stop
Copa Airlines Logo
5:25 am - 2:27 pm
GRU
-
BOS
34h 02m
1 stop
$456Copa Airlines
Thu, Mar 19 - Sun, Mar 29
LATAM Airlines Logo
9:55 am - 8:55 pm
BOS
-
GRU
10h 00mnonstop
LATAM Airlines Logo
10:45 pm - 7:35 am
GRU
-
BOS
9h 50mnonstop
$462LATAM Airlines
Mon, Mar 30 - Thu, Apr 9

Avianca flights from Massachusetts to South America

Our best Avianca deals on Massachusetts to South America flight tickets
Avianca
Apr 26
BOS4:50 pmBoston Logan Intl
10h 15m
1 stop
MDE2:05 amMedellín Jose Maria Cordova Intl
May 11
MDE8:52 pmMedellín Jose Maria Cordova Intl
9h 23m
1 stop
BOS7:15 amBoston Logan Intl
$273
Avianca
Mar 12
BOS8:55 amBoston Logan Intl
12h 20m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
Mar 16
MDE8:10 pmMedellín Jose Maria Cordova Intl
10h 25m
1 stop
BOS7:35 amBoston Logan Intl
$278
Avianca
Apr 26
BOS4:50 pmBoston Logan Intl
14h 24m
2 stops
MDE6:14 amMedellín Jose Maria Cordova Intl
May 11
MDE8:52 pmMedellín Jose Maria Cordova Intl
9h 23m
1 stop
BOS7:15 amBoston Logan Intl
$279

Copa Airlines flights from Massachusetts to South America

Our best Copa Airlines deals on Massachusetts to South America flight tickets
Copa Airlines
Feb 26
BOS7:31 amBoston Logan Intl
9h 32m
1 stop
BOG5:03 pmBogotá El Dorado
Feb 28
BOG4:45 amBogotá El Dorado
8h 57m
1 stop
BOS1:42 pmBoston Logan Intl
$348
Copa Airlines
Jan 27
BOS3:07 pmBoston Logan Intl
7h 41m
1 stop
MDE10:48 pmMedellín Jose Maria Cordova Intl
Feb 4
MDE12:42 pmMedellín Jose Maria Cordova Intl
9h 21m
1 stop
BOS10:03 pmBoston Logan Intl
$364
Copa Airlines
Apr 25
BOS8:43 amBoston Logan Intl
16h 23m
1 stop
BOG12:06 amBogotá El Dorado
May 2
BOG8:35 amBogotá El Dorado
13h 33m
1 stop
BOS11:08 pmBoston Logan Intl
$389

momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Massachusetts to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Tue 3/3

5:27 am-2:13 pm

1 stop8h 46m

Medellín Jose Maria Cordova Intl

Tue 3/10

2:15 pm-10:01 pm

2 stops30h 46m

$268

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sat 2/7

3:43 pm-1:55 pm

1 stop22h 12m

Medellín Jose Maria Cordova Intl

Tue 2/10

3:15 pm-11:57 pm

1 stop8h 42m

$269

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Mon 4/27

4:50 pm-2:05 am

1 stop10h 15m

Medellín Jose Maria Cordova Intl

Mon 5/11

8:52 pm-7:15 am

1 stop9h 23m

$273

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Thu 3/12

8:55 am-8:15 pm

1 stop12h 20m

Medellín Jose Maria Cordova Intl

Mon 3/16

8:10 pm-7:35 am

1 stop10h 25m

$278

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Thu 2/26

3:07 pm-12:05 am

1 stop8h 58m

Bogotá El Dorado

Mon 3/2

10:00 am-10:10 pm

1 stop12h 10m

$348

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Thu 2/5

7:15 am-6:40 pm

1 stop11h 25m

Bogotá El Dorado

Sun 2/8

9:00 am-1:04 am

1 stop16h 04m

$352

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Wed 4/1

5:49 pm-5:40 am

2 stops12h 51m

Bogotá El Dorado

Thu 4/9

2:10 pm-11:59 pm

1 stop8h 49m

$353

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Wed 2/18

11:15 am-9:10 pm

1 stop9h 55m

Bogotá El Dorado

Tue 2/24

3:06 pm-3:27 pm

2 stops24h 21m

$356

BostonSao Paulo

BOS - GRU

BOSGRU

Boston Logan Intl

Thu 3/19

8:44 am-12:10 am

1 stop14h 26m

Sao Paulo Guarulhos Intl

Sun 3/29

5:25 am-2:27 pm

1 stop34h 02m

$456

BostonSao Paulo

BOS - GRU

BOSGRU

Boston Logan Intl

Mon 3/30

9:55 am-8:55 pm

Nonstop10h 00m

Sao Paulo Guarulhos Intl

Thu 4/9

10:45 pm-7:35 am

Nonstop9h 50m

$462

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Massachusetts to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Massachusetts to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $528. If you aren’t able to travel during the month of September, then book flights to South America from Massachusetts during October instead. Flights to South America in October, while not as cheap as those in September, still average around $558.

What is the cheapest Massachusetts to South America flight route?

Fly from Boston Logan Intl to Bogotá El Dorado for the best Massachusetts - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $626 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Massachusetts for as low as $523 on momondo.

What cabin class options are available on Massachusetts to South America flights?

There are 4 cabin classes available to choose from on Massachusetts to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Massachusetts to South America flights?

You could potentially save up to 37% on your flight if you consider stops on a Massachusetts to South America flight.

Cheap Massachusetts to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to South America

Best Price Found

$214

Fastest flight time

6h 10m

Direct flights

Every day

Airports in South America

463 airports
The best one-way flight to South America from Massachusetts in the past 72 hours is $214. The best round-trip flight deal from Massachusetts to South America found on momondo in the last 72 hours is $413.
The fastest flight from Massachusetts to South America takes 6h 10m
Direct flights go from Massachusetts to South America every day.
There are 463 airports in South America. From Massachusetts there are direct flights to Bogotá El Dorado (BOG), Sao Paulo Guarulhos Intl (GRU).
Search flight deals

  • When did momondo last update prices for flights from Massachusetts to South America?

    Prices for flights from Massachusetts to South America refresh daily.

  • How many operators does momondo search for flights from Massachusetts to South America?

  • How old do you have to be to fly from Massachusetts to South America?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Massachusetts to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Massachusetts to South America?

Best airlines flying from Massachusetts to South America

Compare and see reviews for airlines that fly from Massachusetts to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $117Free CancellationRating
7.9
8,118 reviews
Search Delta flights
ArajetPriceFrom $137Free CancellationRating
6.6
43 reviews
Search Arajet flights
AviancaPriceFrom $162Free CancellationRating
6.6
2,487 reviews
Search Avianca flights
GOLPriceFrom $166Free CancellationRating
7.3
1,158 reviews
Search GOL flights
Copa AirlinesPriceFrom $206Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
Air CanadaPriceFrom $234Free CancellationRating
7.1
10,660 reviews
Search Air Canada flights
Spirit AirlinesPriceFrom $253Free CancellationRating
6.3
8,383 reviews
Search Spirit Airlines flights
LATAM AirlinesPriceFrom $262Free CancellationRating
7.5
1,912 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $266Free CancellationRating
7.4
9,204 reviews
Search United Airlines flights
JetBluePriceFrom $274Free CancellationRating
7.2
2,890 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Massachusetts to South America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Massachusetts to South America with flexible booking policies on momondo?

momondo does allow users to show only those flights to South America from Massachusetts which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Massachusetts to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Massachusetts to South America.

I’m not ready to book a flight from Massachusetts to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Massachusetts are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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Find better results for your trip to South America

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