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Cheap flights from Manchester to South Carolina from $486

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to South Carolina departing on 4/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:25 am - 11:00 amMAN-CHS
28h 35m2 stops
Multiple Airlines Logo
11:55 am - 10:35 amCHS-MAN
17h 40m2 stops
$764Multiple Airlines
Find Deal
Fri, Dec 5 - Fri, Dec 12
Multiple Airlines Logo
11:25 am - 12:04 pmMAN-CLT
29h 39m2 stops
Multiple Airlines Logo
12:59 pm - 10:35 amCLT-MAN
16h 36m2 stops
$766Multiple Airlines
Find Deal
Fri, Dec 5 - Fri, Dec 12
Multiple Airlines Logo
9:30 am - 11:00 amMAN-CHS
30h 30m3 stops
Multiple Airlines Logo
11:55 am - 11:55 pmCHS-MAN
31h 00m3 stops
$770Multiple Airlines
Find Deal
Sun, Dec 7 - Sun, Dec 14
Scandinavian Airlines Logo
7:15 pm - 11:54 pmMAN-CLT
33h 39m2 stops
Scandinavian Airlines Logo
1:15 pm - 6:35 pmCLT-MAN
25h 20m2 stops
$851Scandinavian Airlines
Find Deal
Fri, Mar 6 - Tue, Mar 10
Scandinavian Airlines Logo
7:15 pm - 11:50 pmMAN-CLT
33h 35m2 stops
Scandinavian Airlines Logo
10:00 am - 9:30 amCLT-MAN
18h 30m2 stops
$854Scandinavian Airlines
Find Deal
Thu, Nov 6 - Sun, Jan 11
Virgin Atlantic Logo
5:25 pm - 7:03 pmMAN-CAE
30h 38m2 stops
Virgin Atlantic Logo
7:59 pm - 10:10 amCAE-MAN
33h 11m2 stops
$901Virgin Atlantic
Find Deal
Sun, Dec 7 - Sun, Dec 14
United Airlines Logo
1:00 pm - 4:43 pmMAN-CAE
32h 43m2 stops
United Airlines Logo
2:29 pm - 8:45 amCAE-MAN
37h 16m2 stops
$902United Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
Lufthansa Logo
6:25 am - 6:54 pmMAN-CAE
17h 29m2 stops
Lufthansa Logo
10:20 am - 8:40 amCAE-MAN
17h 20m2 stops
$922Lufthansa
Find Deal
Wed, Nov 19 - Wed, Nov 26
Virgin Atlantic Logo
1:30 pm - 11:31 pmMAN-CAE
15h 01m1 stop
Virgin Atlantic Logo
5:45 pm - 7:55 amCAE-MAN
57h 10m2 stops
$944Virgin Atlantic
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Sat, Dec 6 - Sat, Dec 13
United Airlines Logo
6:00 am - 8:00 pmMAN-SAV
19h 00m2 stops
United Airlines Logo
2:00 pm - 12:20 pmSAV-MAN
18h 20m2 stops
$945United Airlines
Find Deal
Thu, Mar 5 - Mon, Mar 9

Lufthansa flights from Manchester to South Carolina

Our best Lufthansa deals on Manchester to South Carolina flight tickets
Lufthansa
Nov 19
MAN6:25 amManchester
17h 29m
2 stops
CAE6:54 pmColumbia Metropolitan
Nov 26
CAE10:20 amColumbia Metropolitan
17h 20m
2 stops
MAN8:40 amManchester
$922
Find similar
Lufthansa
Nov 3
MAN6:25 amManchester
15h 30m
1 stop
CLT4:55 pmCharlotte Douglas
Nov 14
CLT6:50 pmCharlotte Douglas
17h 05m
1 stop
MAN4:55 pmManchester
$1,172
Find similar
Lufthansa
Nov 6
MAN6:25 amManchester
15h 30m
1 stop
CLT4:55 pmCharlotte Douglas
Jan 8
CLT2:54 pmCharlotte Douglas
14h 36m
2 stops
MAN10:30 amManchester
$1,236
Find similar

Scandinavian Airlines flights from Manchester to South Carolina

Our best Scandinavian Airlines deals on Manchester to South Carolina flight tickets
Scandinavian Airlines
Mar 6
MAN7:15 pmManchester
33h 39m
2 stops
CLT11:54 pmCharlotte Douglas
Mar 10
CLT1:15 pmCharlotte Douglas
25h 20m
2 stops
MAN6:35 pmManchester
$851
Find similar
Scandinavian Airlines
Nov 6
MAN7:15 pmManchester
33h 35m
2 stops
CLT11:50 pmCharlotte Douglas
Jan 11
CLT10:00 amCharlotte Douglas
18h 30m
2 stops
MAN9:30 amManchester
$854
Find similar
Scandinavian Airlines
Apr 5
MAN9:40 pmManchester
29h 43m
2 stops
CLT10:23 pmCharlotte Douglas
Apr 19
CLT2:20 pmCharlotte Douglas
37h 35m
2 stops
MAN8:55 amManchester
$870
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Fri 12/5

11:25 am-11:00 am

2 stops28h 35m

Charleston

Fri 12/12

11:55 am-10:35 am

2 stops17h 40m

$764

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 12/5

11:25 am-12:04 pm

2 stops29h 39m

Charlotte Douglas

Fri 12/12

12:59 pm-10:35 am

2 stops16h 36m

$766

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Sun 12/7

9:30 am-11:00 am

3 stops30h 30m

Charleston

Sun 12/14

11:55 am-11:55 pm

3 stops31h 00m

$770

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 3/6

7:15 pm-11:54 pm

2 stops33h 39m

Charlotte Douglas

Tue 3/10

1:15 pm-6:35 pm

2 stops25h 20m

$851

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Thu 11/6

7:15 pm-11:50 pm

2 stops33h 35m

Charlotte Douglas

Sun 1/11

10:00 am-9:30 am

2 stops18h 30m

$854

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Sun 12/7

5:25 pm-7:03 pm

2 stops30h 38m

Columbia Metropolitan

Sun 12/14

7:59 pm-10:10 am

2 stops33h 11m

$901

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Wed 11/19

1:00 pm-4:43 pm

2 stops32h 43m

Columbia Metropolitan

Wed 11/26

2:29 pm-8:45 am

2 stops37h 16m

$902

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Wed 11/19

6:25 am-6:54 pm

2 stops17h 29m

Columbia Metropolitan

Wed 11/26

10:20 am-8:40 am

2 stops17h 20m

$922

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Sat 12/6

1:30 pm-11:31 pm

1 stop15h 01m

Columbia Metropolitan

Sat 12/13

5:45 pm-7:55 am

2 stops57h 10m

$944

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 3/5

6:00 am-8:00 pm

2 stops19h 00m

Savannah/Hilton Head

Mon 3/9

2:00 pm-12:20 pm

2 stops18h 20m

$945

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Manchester to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Manchester is in September. Flight prices, which tend to average around $853, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Manchester during February instead. Flights to South Carolina in February, while not as cheap as those in September, still average around $867.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Manchester to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $1,350. Try not to purchase tickets at noon because they tend to be around $1,652. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $1,024 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Manchester for as low as $926 on momondo.

Can stopping save me money on Manchester to South Carolina flights?

You could potentially save up to 3% on your flight if you consider stops on a Manchester to South Carolina flight.

Cheap Manchester to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to South Carolina

Direct flights

None
There are no direct flights from Manchester to South Carolina. There are no popular flight routes from Manchester to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Manchester Airport to South Carolina?

    Prices for flights from Manchester Airport to South Carolina were last updated today.

  • How old do you have to be to fly from Manchester Airport to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Manchester Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Manchester.

Can I find flights from Manchester to South Carolina with flexible booking policies on momondo?

Flights from Manchester to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Manchester to South Carolina?

momondo helps you find the best flight between Manchester and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Manchester to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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