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Cheap flights from Maine to South Carolina from $34

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Maine to South Carolina departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Maine to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
9:57 am - 12:25 pm
BOS
-
MYR
2h 28mnonstop
Spirit Airlines Logo
1:20 pm - 3:27 pm
MYR
-
BOS
2h 07mnonstop
$96Spirit Airlines
Mon, Mar 2 - Tue, Mar 10
Spirit Airlines Logo
9:57 am - 12:25 pm
BOS
-
MYR
2h 28mnonstop
Spirit Airlines Logo
1:20 pm - 3:27 pm
MYR
-
BOS
2h 07mnonstop
$97Spirit Airlines
Wed, Feb 25 - Tue, Mar 3
Multiple Airlines Logo
5:27 am - 5:40 pm
BOS
-
CHS
12h 13m
1 stop
Multiple Airlines Logo
10:20 am - 12:35 pm
CHS
-
BOS
2h 15mnonstop
$148Multiple Airlines
Thu, Mar 5 - Sun, Mar 8
Southwest Logo
5:50 am - 10:35 am
BOS
-
SAV
4h 45m
1 stop
Southwest Logo
7:45 pm - 12:05 am
SAV
-
BOS
4h 20m
1 stop
$151Southwest
Tue, Mar 3 - Mon, Mar 9
Southwest Logo
2:50 pm - 8:55 pm
BOS
-
CHS
6h 05m
1 stop
Southwest Logo
7:55 am - 12:25 pm
CHS
-
BOS
4h 30m
1 stop
$151Southwest
Sat, Feb 28 - Tue, Mar 3
Delta Logo
12:05 pm - 3:00 pm
BOS
-
SAV
2h 55mnonstop
Delta Logo
3:41 pm - 6:10 pm
SAV
-
BOS
2h 29mnonstop
$157Delta
Wed, Feb 25 - Wed, Mar 4
Delta Logo
11:05 am - 2:04 pm
BOS
-
SAV
2h 59mnonstop
Delta Logo
2:25 pm - 4:52 pm
SAV
-
BOS
2h 27mnonstop
$162Delta
Tue, Feb 10 - Sat, Feb 14
American Airlines Logo
6:52 pm - 11:57 pm
BOS
-
SAV
5h 05m
1 stop
American Airlines Logo
10:28 am - 3:46 pm
SAV
-
BOS
5h 18m
1 stop
$168American Airlines
Fri, Feb 20 - Wed, Feb 25
Multiple Airlines Logo
5:27 am - 6:15 pm
BOS
-
CAE
12h 48m
1 stop
Multiple Airlines Logo
7:04 pm - 11:44 pm
CAE
-
BOS
28h 40m
1 stop
$172Multiple Airlines
Mon, Feb 23 - Mon, Mar 2
American Airlines Logo
1:00 pm - 8:34 pm
BOS
-
CAE
7h 34m
1 stop
American Airlines Logo
6:25 am - 11:59 am
CAE
-
BOS
5h 34m
1 stop
$211American Airlines
Wed, Mar 25 - Tue, Mar 31

Delta flights from Maine to South Carolina

Our best Delta deals on Maine to South Carolina flight tickets
Delta
Feb 25
BOS12:05 pmBoston Logan Intl
2h 55m
SAV3:00 pmSavannah/Hilton Head
Mar 4
SAV3:41 pmSavannah/Hilton Head
2h 29m
BOS6:10 pmBoston Logan Intl
$157
Delta
Feb 22
BOS6:00 amBoston Logan Intl
5h 18m
1 stop
CHS11:18 amCharleston
Feb 25
CHS4:45 pmCharleston
2h 24m
BOS7:09 pmBoston Logan Intl
$162
Delta
Mar 10
BOS12:50 pmBoston Logan Intl
2h 36m
CHS3:26 pmCharleston
Mar 17
CHS11:15 amCharleston
6h 00m
1 stop
BOS5:15 pmBoston Logan Intl
$167

Spirit Airlines flights from Maine to South Carolina

Our best Spirit Airlines deals on Maine to South Carolina flight tickets
Spirit Airlines
Mar 2
BOS9:57 amBoston Logan Intl
2h 28m
MYR12:25 pmMyrtle Beach Intl
Mar 7
MYR9:53 amMyrtle Beach Intl
1h 59m
BOS11:52 amBoston Logan Intl
$96
Spirit Airlines
Feb 3
BOS6:39 pmBoston Logan Intl
2h 25m
MYR9:04 pmMyrtle Beach Intl
Feb 10
MYR3:39 pmMyrtle Beach Intl
2h 05m
BOS5:44 pmBoston Logan Intl
$97
Spirit Airlines
Mar 22
BOS6:29 pmBoston Logan Intl
2h 19m
MYR8:48 pmMyrtle Beach Intl
Mar 25
MYR6:37 pmMyrtle Beach Intl
5h 22m
1 stop
BOS11:59 pmBoston Logan Intl
$98

momondo Fare Finder

 
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Mon 3/2

9:57 am-12:25 pm

Nonstop2h 28m

Myrtle Beach Intl

Tue 3/10

1:20 pm-3:27 pm

Nonstop2h 07m

$96

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Wed 2/25

9:57 am-12:25 pm

Nonstop2h 28m

Myrtle Beach Intl

Tue 3/3

1:20 pm-3:27 pm

Nonstop2h 07m

$97

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Thu 3/5

5:27 am-5:40 pm

1 stop12h 13m

Charleston

Sun 3/8

10:20 am-12:35 pm

Nonstop2h 15m

$148

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Tue 3/3

5:50 am-10:35 am

1 stop4h 45m

Savannah/Hilton Head

Mon 3/9

7:45 pm-12:05 am

1 stop4h 20m

$151

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Sat 2/28

2:50 pm-8:55 pm

1 stop6h 05m

Charleston

Tue 3/3

7:55 am-12:25 pm

1 stop4h 30m

$151

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 2/25

12:05 pm-3:00 pm

Nonstop2h 55m

Savannah/Hilton Head

Wed 3/4

3:41 pm-6:10 pm

Nonstop2h 29m

$157

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Tue 2/10

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Sat 2/14

2:25 pm-4:52 pm

Nonstop2h 27m

$162

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Fri 2/20

6:52 pm-11:57 pm

1 stop5h 05m

Savannah/Hilton Head

Wed 2/25

10:28 am-3:46 pm

1 stop5h 18m

$168

BostonColumbia

BOS - CAE

BOSCAE

Boston Logan Intl

Mon 2/23

5:27 am-6:15 pm

1 stop12h 48m

Columbia Metropolitan

Mon 3/2

7:04 pm-11:44 pm

1 stop28h 40m

$172

BostonColumbia

BOS - CAE

BOSCAE

Boston Logan Intl

Wed 3/25

1:00 pm-8:34 pm

1 stop7h 34m

Columbia Metropolitan

Tue 3/31

6:25 am-11:59 am

1 stop5h 34m

$211

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Maine to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Maine is in March. Flight prices, which tend to average around $158, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to South Carolina from Maine during January instead. Flights to South Carolina in January, while not as cheap as those in March, still average around $199.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $161. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $264.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Maine to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $147. Try not to purchase tickets in the afternoon because they tend to be around $190. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Maine to South Carolina flight route?

Fly from Portland to Charleston for the best Maine - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Maine when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $252 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Maine for as low as $142 on momondo.

What cabin class options are available on Maine to South Carolina flights?

There are 2 cabin classes available to choose from on Maine to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Maine to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Maine to South Carolina.

Cheap Maine to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maine to South Carolina

Best Price Found

$81

Fastest flight time

2h 19m

Direct flights

Every day

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Maine in the past 72 hours is $81. The best round-trip flight deal from Maine to South Carolina found on momondo in the last 72 hours is $163.
The fastest flight from Maine to South Carolina takes 2h 19m
Direct flights go from Maine to South Carolina every day.
There are 57 airports in South Carolina. From Maine there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Maine to South Carolina?

    Prices for flights from Maine to South Carolina are updated daily.

  • How many operators does momondo search for flights from Maine to South Carolina?

  • How old do you have to be to fly from Maine to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Maine to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Maine to South Carolina?

Best airlines flying from Maine to South Carolina

Compare and see reviews for airlines that fly from Maine to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $90Free CancellationRating
8.2
263 reviews
Search Breeze Airways flights
DeltaPriceFrom $147Free CancellationRating
7.9
8,127 reviews
Search Delta flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,267 reviews
Search Southwest flights
American AirlinesPriceFrom $236Free CancellationRating
7.2
11,206 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Maine to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Maine to South Carolina for you.

Can I find flights from Maine to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Maine with this policy.

How can momondo help me find flights from Maine to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Maine to South Carolina.

I’m not ready to book a flight from Maine to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Maine are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Sat 2/28
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