Cheap flights from Maine to South Carolina from $66

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Maine to South Carolina departing on 9/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Maine to South Carolina

Cheap round-trip flights

JetBlue Logo
12:30 pm - 3:15 pmBOS-SAV
2h 45mnonstop
JetBlue Logo
10:37 am - 1:05 pmSAV-BOS
2h 28mnonstop
$115JetBlue
Find Deal
Thu, Sep 11 - Mon, Sep 15
JetBlue Logo
7:50 am - 10:31 amBOS-SAV
2h 41mnonstop
JetBlue Logo
4:10 pm - 6:38 pmSAV-BOS
2h 28mnonstop
$127JetBlue
Find Deal
Sat, Sep 13 - Wed, Sep 17
Delta Logo
6:05 am - 11:34 amBOS-SAV
5h 29m1 stop
Delta Logo
3:34 pm - 6:10 pmSAV-BOS
2h 36mnonstop
$137Delta
Find Deal
Sat, Sep 13 - Sat, Sep 27
Breeze Airways Logo
6:05 pm - 8:43 pmPWM-CHS
2h 38mnonstop
Breeze Airways Logo
3:04 pm - 5:25 pmCHS-PWM
2h 21mnonstop
$138Breeze Airways
Find Deal
Fri, Oct 17 - Mon, Oct 20
Breeze Airways Logo
6:05 pm - 8:43 pmPWM-CHS
2h 38mnonstop
Breeze Airways Logo
3:04 pm - 5:25 pmCHS-PWM
2h 21mnonstop
$143Breeze Airways
Find Deal
Fri, Sep 12 - Mon, Sep 15
Delta Logo
1:45 pm - 8:57 pmBOS-SAV
7h 12m1 stop
Delta Logo
6:58 pm - 1:22 amSAV-BOS
6h 24m1 stop
$147Delta
Find Deal
Sat, Nov 8 - Tue, Nov 11
Southwest Logo
3:20 pm - 8:20 pmBOS-SAV
5h 00m1 stop
Southwest Logo
6:45 pm - 11:25 pmSAV-BOS
4h 40m1 stop
$151Southwest
Find Deal
Wed, Oct 15 - Fri, Oct 17
Southwest Logo
5:40 am - 10:15 amBOS-SAV
4h 35m1 stop
Southwest Logo
12:40 pm - 9:00 pmSAV-BOS
8h 20m1 stop
$156Southwest
Find Deal
Wed, Oct 1 - Fri, Oct 3
American Airlines Logo
3:55 pm - 11:22 pmBOS-AGS
7h 27m1 stop
American Airlines Logo
5:35 pm - 9:47 pmAGS-BOS
4h 12m1 stop
$167American Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
American Airlines Logo
10:30 am - 5:10 pmBOS-AGS
6h 40m2 stops
American Airlines Logo
5:35 pm - 9:47 pmAGS-BOS
4h 12m1 stop
$172American Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13

Spirit Airlines flights from Maine to South Carolina

Our best Spirit Airlines deals on Maine to South Carolina flight tickets
Spirit Airlines
Sep 20
BOS6:00 amBoston Logan Intl
2h 16m
MYR8:16 amMyrtle Beach Intl
Sep 22
MYR9:04 pmMyrtle Beach Intl
2h 06m
BOS11:10 pmBoston Logan Intl
Spirit Airlines
Sep 20
BOS6:00 amBoston Logan Intl
2h 16m
MYR8:16 amMyrtle Beach Intl
Sep 25
MYR9:04 pmMyrtle Beach Intl
2h 06m
BOS11:10 pmBoston Logan Intl
Spirit Airlines
Sep 20
BOS6:00 amBoston Logan Intl
2h 16m
MYR8:16 amMyrtle Beach Intl
Oct 1
MYR9:04 pmMyrtle Beach Intl
2h 06m
BOS11:10 pmBoston Logan Intl

Delta flights from Maine to South Carolina

Our best Delta deals on Maine to South Carolina flight tickets
Delta
Sep 13
BOS6:05 amBoston Logan Intl
5h 29m
1 stop
SAV11:34 amSavannah/Hilton Head
Sep 27
SAV3:34 pmSavannah/Hilton Head
2h 36m
BOS6:10 pmBoston Logan Intl
Delta
Sep 27
BOS1:00 pmBoston Logan Intl
2h 30m
CHS3:30 pmCharleston
Sep 30
CHS4:05 pmCharleston
2h 25m
BOS6:30 pmBoston Logan Intl
Delta
Sep 24
BOS6:05 amBoston Logan Intl
6h 02m
1 stop
CHS12:07 pmCharleston
Sep 27
CHS4:40 pmCharleston
2h 24m
BOS7:04 pmBoston Logan Intl

momondo Fare Finder

 
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Thu 9/11

12:30 pm-3:15 pm

Nonstop2h 45m

Savannah/Hilton Head

Mon 9/15

10:37 am-1:05 pm

Nonstop2h 28m

$115

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Sat 9/13

7:50 am-10:31 am

Nonstop2h 41m

Savannah/Hilton Head

Wed 9/17

4:10 pm-6:38 pm

Nonstop2h 28m

$127

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Sat 9/13

6:05 am-11:34 am

1 stop5h 29m

Savannah/Hilton Head

Sat 9/27

3:34 pm-6:10 pm

Nonstop2h 36m

$137

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 10/17

6:05 pm-8:43 pm

Nonstop2h 38m

Charleston

Mon 10/20

3:04 pm-5:25 pm

Nonstop2h 21m

$138

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 9/12

6:05 pm-8:43 pm

Nonstop2h 38m

Charleston

Mon 9/15

3:04 pm-5:25 pm

Nonstop2h 21m

$143

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Sat 11/8

1:45 pm-8:57 pm

1 stop7h 12m

Savannah/Hilton Head

Tue 11/11

6:58 pm-1:22 am

1 stop6h 24m

$147

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 10/15

3:20 pm-8:20 pm

1 stop5h 00m

Savannah/Hilton Head

Fri 10/17

6:45 pm-11:25 pm

1 stop4h 40m

$151

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 10/1

5:40 am-10:15 am

1 stop4h 35m

Savannah/Hilton Head

Fri 10/3

12:40 pm-9:00 pm

1 stop8h 20m

$156

BostonAugusta

BOS - AGS

BOSAGS

Boston Logan Intl

Tue 9/9

3:55 pm-11:22 pm

1 stop7h 27m

Augusta Bush Field

Sat 9/13

5:35 pm-9:47 pm

1 stop4h 12m

$167

BostonAugusta

BOS - AGS

BOSAGS

Boston Logan Intl

Tue 9/9

10:30 am-5:10 pm

2 stops6h 40m

Augusta Bush Field

Sat 9/13

5:35 pm-9:47 pm

1 stop4h 12m

$172

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Maine to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Maine is in March. Flight prices, which tend to average around $163, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to South Carolina from Maine during February instead. Flights to South Carolina in February, while not as cheap as those in March, still average around $184.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $158. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $264.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Maine to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $147. Try not to purchase tickets in the afternoon because they tend to be around $200. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Maine to South Carolina flight route?

Fly from Portland to Charleston for the best Maine - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Maine when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $256 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Maine for as low as $161 on momondo.

What cabin class options are available on Maine to South Carolina flights?

There are 2 cabin classes available to choose from on Maine to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Maine to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Maine to South Carolina.

Cheap Maine to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maine to South Carolina

Best Price Found

$144

Fastest flight time

2h 16m

Direct flights

Every day

Airports in South Carolina

2 airports
The best one-way flight to South Carolina from Maine in the past 72 hours is $144. The best round-trip flight deal from Maine to South Carolina found on momondo in the last 72 hours is $121.
The fastest flight from Maine to South Carolina takes 2h 16m
Direct flights go from Maine to South Carolina every day.
There are 2 airports near South Carolina: Myrtle Beach Intl (MYR), Charlotte Douglas (CLT)
  • When did momondo last update prices for flights from Maine to South Carolina?

    Prices for flights from Maine to South Carolina are updated daily.

  • How many operators does momondo search for flights from Maine to South Carolina?

  • How old do you have to be to fly from Maine to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Maine to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Maine to South Carolina?

Best airlines flying from Maine to South Carolina

Compare and see reviews for airlines that fly from Maine to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $90Free CancellationRating
8.0
199 reviews
Search Breeze Airways flights
DeltaPriceFrom $162Free CancellationRating
7.9
7,977 reviews
Search Delta flights
United AirlinesPriceFrom $188Free CancellationRating
7.4
8,944 reviews
Search United Airlines flights
American AirlinesPriceFrom $236Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $256Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Maine to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Maine to South Carolina for you.

Can I find flights from Maine to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Maine with this policy.

How can momondo help me find flights from Maine to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Maine to South Carolina.

I’m not ready to book a flight from Maine to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Maine are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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1 adult
Tue 9/2
Tue 9/9

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