Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Lafayette to Knoxville from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Lafayette to Knoxville departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Lafayette to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:15 pm - 11:46 pm
LFT
-
TYS
5h 31m
1 stop
Delta Logo
5:30 am - 10:28 am
TYS
-
LFT
5h 58m
1 stop
$379Delta
Fri, Jul 24 - Wed, Jul 29
Delta Logo
3:10 pm - 9:44 pm
LFT
-
TYS
5h 34m
1 stop
Delta Logo
5:57 pm - 10:02 pm
TYS
-
LFT
5h 05m
1 stop
$393Delta
Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
5:36 pm - 11:52 pm
LFT
-
TYS
5h 16m
1 stop
American Airlines Logo
5:36 am - 10:17 am
TYS
-
LFT
5h 41m
1 stop
$405American Airlines
Fri, Jul 24 - Wed, Jul 29
United Airlines Logo
12:03 pm - 7:56 pm
LFT
-
TYS
6h 53m
1 stop
United Airlines Logo
9:00 am - 3:31 pm
TYS
-
LFT
7h 31m
1 stop
$429United Airlines
Sat, Apr 11 - Tue, Apr 14
Delta Logo
5:15 pm - 11:47 pm
LFT
-
TYS
5h 32m
1 stop
Delta Logo
7:20 pm - 9:59 pm
TYS
-
LFT
3h 39m
1 stop
$483Delta
Fri, Sep 4 - Mon, Sep 7
United Airlines Logo
12:03 pm - 7:56 pm
LFT
-
TYS
6h 53m
1 stop
United Airlines Logo
5:15 pm - 9:06 pm
TYS
-
LFT
4h 51m
1 stop
$484United Airlines
Sat, Apr 11 - Tue, Apr 14
United Airlines Logo
12:03 pm - 6:15 pm
LFT
-
TYS
5h 12m
1 stop
United Airlines Logo
5:15 pm - 9:06 pm
TYS
-
LFT
4h 51m
1 stop
$489United Airlines
Sat, Apr 11 - Tue, Apr 14
American Airlines Logo
1:53 pm - 11:59 pm
LFT
-
TYS
9h 06m
2 stops
American Airlines Logo
5:36 am - 10:17 am
TYS
-
LFT
5h 41m
1 stop
$502American Airlines
Fri, Jul 24 - Wed, Jul 29
American Airlines Logo
1:53 pm - 11:59 pm
LFT
-
TYS
9h 06m
2 stops
American Airlines Logo
5:36 am - 10:17 am
TYS
-
LFT
5h 41m
1 stop
$505American Airlines
Fri, Jul 24 - Wed, Jul 29
United Airlines Logo
5:15 am - 7:42 pm
LFT
-
TYS
13h 27m
2 stops
United Airlines Logo
9:00 am - 3:31 pm
TYS
-
LFT
7h 31m
1 stop
$524United Airlines
Sat, Apr 11 - Tue, Apr 14

United Airlines flights from Lafayette to Knoxville

Our best United Airlines deals on Lafayette to Knoxville flight tickets
United Airlines
Apr 11
LFT12:03 pmLafayette Regional
6h 53m
1 stop
TYS7:56 pmKnoxville McGhee Tyson
Apr 14
TYS9:00 amKnoxville McGhee Tyson
7h 31m
1 stop
LFT3:31 pmLafayette Regional
$429
United Airlines
Apr 11
LFT12:03 pmLafayette Regional
6h 53m
1 stop
TYS7:56 pmKnoxville McGhee Tyson
Apr 14
TYS5:15 pmKnoxville McGhee Tyson
4h 51m
1 stop
LFT9:06 pmLafayette Regional
$484
United Airlines
Apr 11
LFT12:03 pmLafayette Regional
5h 12m
1 stop
TYS6:15 pmKnoxville McGhee Tyson
Apr 14
TYS5:15 pmKnoxville McGhee Tyson
4h 51m
1 stop
LFT9:06 pmLafayette Regional
$489

Delta flights from Lafayette to Knoxville

Our best Delta deals on Lafayette to Knoxville flight tickets
Delta
Jul 24
LFT5:15 pmLafayette Regional
5h 31m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Jul 29
TYS5:30 amKnoxville McGhee Tyson
5h 58m
1 stop
LFT10:28 amLafayette Regional
$379
Delta
Jun 12
LFT3:10 pmLafayette Regional
5h 34m
1 stop
TYS9:44 pmKnoxville McGhee Tyson
Jun 16
TYS5:57 pmKnoxville McGhee Tyson
5h 05m
1 stop
LFT10:02 pmLafayette Regional
$393
Delta
Sep 4
LFT5:15 pmLafayette Regional
5h 32m
1 stop
TYS11:47 pmKnoxville McGhee Tyson
Sep 7
TYS7:20 pmKnoxville McGhee Tyson
3h 39m
1 stop
LFT9:59 pmLafayette Regional
$483

momondo Fare Finder

 
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 7/24

5:15 pm-11:46 pm

1 stop5h 31m

Knoxville McGhee Tyson

Wed 7/29

5:30 am-10:28 am

1 stop5h 58m

$379

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

3:10 pm-9:44 pm

1 stop5h 34m

Knoxville McGhee Tyson

Tue 6/16

5:57 pm-10:02 pm

1 stop5h 05m

$393

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 7/24

5:36 pm-11:52 pm

1 stop5h 16m

Knoxville McGhee Tyson

Wed 7/29

5:36 am-10:17 am

1 stop5h 41m

$405

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 4/11

12:03 pm-7:56 pm

1 stop6h 53m

Knoxville McGhee Tyson

Tue 4/14

9:00 am-3:31 pm

1 stop7h 31m

$429
Quickest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 9/4

5:15 pm-11:47 pm

1 stop5h 32m

Knoxville McGhee Tyson

Mon 9/7

7:20 pm-9:59 pm

1 stop3h 39m

$483

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 4/11

12:03 pm-7:56 pm

1 stop6h 53m

Knoxville McGhee Tyson

Tue 4/14

5:15 pm-9:06 pm

1 stop4h 51m

$484

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 4/11

12:03 pm-6:15 pm

1 stop5h 12m

Knoxville McGhee Tyson

Tue 4/14

5:15 pm-9:06 pm

1 stop4h 51m

$489

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 7/24

1:53 pm-11:59 pm

2 stops9h 06m

Knoxville McGhee Tyson

Wed 7/29

5:36 am-10:17 am

1 stop5h 41m

$502

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 7/24

1:53 pm-11:59 pm

2 stops9h 06m

Knoxville McGhee Tyson

Wed 7/29

5:36 am-10:17 am

1 stop5h 41m

$505

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 4/11

5:15 am-7:42 pm

2 stops13h 27m

Knoxville McGhee Tyson

Tue 4/14

9:00 am-3:31 pm

1 stop7h 31m

$524

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Lafayette to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Lafayette Regional to Knoxville McGhee Tyson?

American Airlines and United Airlines are the most popular carriers operating from Lafayette Regional to Knoxville McGhee Tyson

When to book flights from Lafayette to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Lafayette to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Lafayette to Knoxville (LFT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Lafayette to Knoxville

Fastest flight time

5h 31m

Direct flights

None
The fastest flight from Lafayette to Knoxville takes 5h 31m
There are no direct flights from Lafayette to Knoxville. There are no popular flight routes from Lafayette to Knoxville.
Search flight deals

  • How far is Lafayette Regional to Knoxville McGhee Tyson by plane?

    There are 613.1 mi between Lafayette Regional and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 5h 31m.

  • When did momondo last update prices for flights from Lafayette Regional Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Lafayette Regional Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Lafayette Regional Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Lafayette Regional Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lafayette Regional Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Lafayette to Knoxville?

Best airlines flying from Lafayette to Knoxville

Compare and see reviews for airlines that fly from Lafayette to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $279Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Lafayette to Knoxville?

It is quick and easy to find Lafayette to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Lafayette to Knoxville with flexible booking policies on momondo?

Flights from Lafayette to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Lafayette to Knoxville?

Once you have performed a search for Lafayette to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Lafayette to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Lafayette and alert you when they change.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 4/17
Fri 4/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States