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Cheap flights from Lafayette to Knoxville from $308

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Lafayette to Knoxville departing on 6/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Lafayette to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:25 pm - 11:55 pm
LFT
-
TYS
5h 30m
1 stop
American Airlines Logo
5:37 am - 10:21 am
TYS
-
LFT
5h 44m
1 stop
$317American Airlines
Fri, Jun 12 - Tue, Jun 16
Delta Logo
5:03 pm - 11:52 pm
LFT
-
TYS
5h 49m
1 stop
Delta Logo
6:05 pm - 9:41 pm
TYS
-
LFT
4h 36m
1 stop
$334Delta
Tue, Jul 14 - Tue, Jul 21
Delta Logo
5:03 pm - 11:54 pm
LFT
-
TYS
5h 51m
1 stop
Delta Logo
5:40 am - 10:57 am
TYS
-
LFT
6h 17m
1 stop
$344Delta
Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
5:36 pm - 11:52 pm
LFT
-
TYS
5h 16m
1 stop
American Airlines Logo
5:36 am - 10:22 am
TYS
-
LFT
5h 46m
1 stop
$347American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
5:25 pm - 11:55 pm
LFT
-
TYS
5h 30m
1 stop
American Airlines Logo
5:37 am - 10:21 am
TYS
-
LFT
5h 44m
1 stop
$349American Airlines
Fri, Jun 12 - Wed, Jun 17
United Airlines Logo
5:20 am - 12:57 pm
LFT
-
TYS
6h 37m
1 stop
United Airlines Logo
7:15 am - 11:15 am
TYS
-
LFT
5h 00m
1 stop
$365United Airlines
Sat, Aug 29 - Wed, Sep 2
American Airlines Logo
5:25 pm - 11:55 pm
LFT
-
TYS
5h 30m
1 stop
American Airlines Logo
5:37 am - 10:21 am
TYS
-
LFT
5h 44m
1 stop
$387American Airlines
Fri, Jun 12 - Wed, Jun 17
American Airlines Logo
5:36 pm - 11:52 pm
LFT
-
TYS
5h 16m
1 stop
American Airlines Logo
5:36 am - 10:22 am
TYS
-
LFT
5h 46m
1 stop
$389American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
1:53 pm - 11:59 pm
LFT
-
TYS
9h 06m
2 stops
American Airlines Logo
5:36 am - 10:22 am
TYS
-
LFT
5h 46m
1 stop
$422American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
8:10 am - 1:31 pm
LFT
-
TYS
4h 21m
1 stop
American Airlines Logo
6:00 am - 10:19 am
TYS
-
LFT
5h 19m
1 stop
$435American Airlines
Fri, Aug 28 - Mon, Aug 31

Delta flights from Lafayette to Knoxville

Our best Delta deals on Lafayette to Knoxville flight tickets
Delta
Jul 14
LFT5:03 pmLafayette Regional
5h 49m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Jul 21
TYS6:05 pmKnoxville McGhee Tyson
4h 36m
1 stop
LFT9:41 pmLafayette Regional
$334
Delta
Jun 12
LFT6:00 amLafayette Regional
4h 09m
1 stop
TYS11:09 amKnoxville McGhee Tyson
Jun 17
TYS11:55 amKnoxville McGhee Tyson
3h 44m
1 stop
LFT2:39 pmLafayette Regional
$344

American Airlines flights from Lafayette to Knoxville

Our best American Airlines deals on Lafayette to Knoxville flight tickets
American Airlines
Jun 12
LFT5:25 pmLafayette Regional
5h 30m
1 stop
TYS11:55 pmKnoxville McGhee Tyson
Jun 16
TYS5:37 amKnoxville McGhee Tyson
5h 44m
1 stop
LFT10:21 amLafayette Regional
$317
American Airlines
May 30
LFT5:27 pmLafayette Regional
5h 29m
1 stop
TYS11:56 pmKnoxville McGhee Tyson
Jun 3
TYS5:36 amKnoxville McGhee Tyson
5h 45m
1 stop
LFT10:21 amLafayette Regional
$347
American Airlines
Jun 12
LFT5:25 pmLafayette Regional
5h 30m
1 stop
TYS11:55 pmKnoxville McGhee Tyson
Jun 17
TYS5:37 amKnoxville McGhee Tyson
5h 44m
1 stop
LFT10:21 amLafayette Regional
$349

momondo Fare Finder

 
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:25 pm-11:55 pm

1 stop5h 30m

Knoxville McGhee Tyson

Tue 6/16

5:37 am-10:21 am

1 stop5h 44m

$317

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:03 pm-11:52 pm

1 stop5h 49m

Knoxville McGhee Tyson

Tue 7/21

6:05 pm-9:41 pm

1 stop4h 36m

$334

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:03 pm-11:54 pm

1 stop5h 51m

Knoxville McGhee Tyson

Tue 6/16

5:40 am-10:57 am

1 stop6h 17m

$344

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:36 pm-11:52 pm

1 stop5h 16m

Knoxville McGhee Tyson

Tue 7/21

5:36 am-10:22 am

1 stop5h 46m

$347

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:25 pm-11:55 pm

1 stop5h 30m

Knoxville McGhee Tyson

Wed 6/17

5:37 am-10:21 am

1 stop5h 44m

$349

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 8/29

5:20 am-12:57 pm

1 stop6h 37m

Knoxville McGhee Tyson

Wed 9/2

7:15 am-11:15 am

1 stop5h 00m

$365

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:25 pm-11:55 pm

1 stop5h 30m

Knoxville McGhee Tyson

Wed 6/17

5:37 am-10:21 am

1 stop5h 44m

$387

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:36 pm-11:52 pm

1 stop5h 16m

Knoxville McGhee Tyson

Tue 7/21

5:36 am-10:22 am

1 stop5h 46m

$389

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

1:53 pm-11:59 pm

2 stops9h 06m

Knoxville McGhee Tyson

Tue 7/21

5:36 am-10:22 am

1 stop5h 46m

$422
Quickest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 8/28

8:10 am-1:31 pm

1 stop4h 21m

Knoxville McGhee Tyson

Mon 8/31

6:00 am-10:19 am

1 stop5h 19m

$435

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Lafayette to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Lafayette, with most prices found around $0. If you aren’t able to travel during the month of July, then book flights to Knoxville from Lafayette during May instead. Flights to Knoxville in May, while not as cheap as those in July, still average around $313.

When to book flights from Lafayette to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Lafayette to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Lafayette to Knoxville (LFT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Lafayette to Knoxville

Fastest flight time

3h 43m

Direct flights

None
The fastest flight from Lafayette to Knoxville takes 3h 43m
There are no direct flights from Lafayette to Knoxville. There are no popular flight routes from Lafayette to Knoxville.
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Frequently asked questions about flying from Lafayette to Knoxville

  • How far is Lafayette Regional to Knoxville McGhee Tyson by plane?

    There are 613.1 mi between Lafayette Regional and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 3h 43m.

  • When did momondo last update prices for flights from Lafayette Regional Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Lafayette Regional Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Lafayette Regional Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Lafayette Regional Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lafayette Regional Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Lafayette to Knoxville?

Best airlines flying from Lafayette to Knoxville

Compare and see reviews for airlines that fly from Lafayette to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $288Free CancellationRating
7.1
11,648 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Lafayette to Knoxville?

It is quick and easy to find Lafayette to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Lafayette to Knoxville with flexible booking policies on momondo?

Flights from Lafayette to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Lafayette to Knoxville?

Once you have performed a search for Lafayette to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Lafayette to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Lafayette and alert you when they change.

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