Cheap flights from New York LaGuardia Airport to South Carolina from $48

The cheapest month to fly to South Carolina from New York LaGuardia Airport is in January. Flight prices, which tend to average around $201, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from New York LaGuardia Airport during February instead. Flights to South Carolina in February, while not as cheap as those in January, still average around $209.

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $227. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $336.

Our data shows that the cheapest New York LaGuardia Airport to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $273. Try not to purchase tickets in the evening because they tend to be around $310. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from New York LaGuardia to Myrtle Beach Intl for the best New York LaGuardia - South Carolina flight prices

You are more likely to see cheaper flights to South Carolina from New York LaGuardia Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $276 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from New York LaGuardia Airport for as low as $203 on momondo.

There are 4 cabin classes available to choose from on New York LaGuardia to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, United Airlines, and Spirit Airlines are the most popular carriers operating from New York LaGuardia to South Carolina

Delta, American Airlines and Spirit Airlines are the top three most popular airlines that fly to South Carolina from New York LaGuardia Airport according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

The number of flights available between New York LaGuardia Airport and South Carolina is 55 per day as of April 2026. The most frequent departure time is 7:00PM, with 43% of daily flights leaving in the afternoon.

390 flights are operational weekly from New York LaGuardia Airport to South Carolina as of April 2026. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.