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Cheap flights from La Crosse to South Carolina from $418

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to South Carolina departing on 10/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from La Crosse to South Carolina

Cheap round-trip flights

American Airlines Logo
6:15 pm - 11:53 pmLSE-CLT
4h 38m1 stop
American Airlines Logo
6:08 pm - 11:49 pmCLT-LSE
6h 41m1 stop
$458American Airlines
Find Deal
mar., oct. 14 - vie., nov. 14
American Airlines Logo
10:54 am - 7:19 pmLSE-CLT
7h 25m2 stops
American Airlines Logo
11:18 am - 5:32 pmCLT-LSE
7h 14m1 stop
$464American Airlines
Find Deal
mar., oct. 14 - vie., nov. 14
American Airlines Logo
6:00 am - 12:35 pmLSE-CLT
5h 35m1 stop
American Airlines Logo
11:30 am - 5:32 pmCLT-LSE
7h 02m1 stop
$475American Airlines
Find Deal
mar., oct. 7 - dom., nov. 2
American Airlines Logo
6:15 pm - 11:53 pmLSE-CLT
4h 38m1 stop
American Airlines Logo
10:40 am - 5:32 pmCLT-LSE
7h 52m2 stops
$481American Airlines
Find Deal
mar., oct. 14 - vie., nov. 14
American Airlines Logo
10:54 am - 7:19 pmLSE-CLT
7h 25m2 stops
American Airlines Logo
10:40 am - 5:32 pmCLT-LSE
7h 52m2 stops
$504American Airlines
Find Deal
mar., oct. 14 - vie., nov. 14
American Airlines Logo
6:00 am - 12:23 pmLSE-CLT
5h 23m1 stop
American Airlines Logo
6:00 pm - 11:26 pmCLT-LSE
6h 26m1 stop
$518American Airlines
Find Deal
jue., oct. 9 - lun., oct. 13
American Airlines Logo
6:15 pm - 12:15 amLSE-CHS
5h 00m1 stop
American Airlines Logo
7:45 pm - 11:26 pmCHS-LSE
4h 41m1 stop
$548American Airlines
Find Deal
jue., oct. 16 - lun., oct. 20
American Airlines Logo
6:15 pm - 12:15 amLSE-CHS
5h 00m1 stop
American Airlines Logo
6:36 pm - 11:26 pmCHS-LSE
5h 50m2 stops
$554American Airlines
Find Deal
jue., oct. 16 - lun., oct. 20
American Airlines Logo
10:54 am - 7:19 pmLSE-CLT
7h 25m2 stops
American Airlines Logo
10:40 am - 5:32 pmCLT-LSE
7h 52m2 stops
$563American Airlines
Find Deal
mar., oct. 14 - vie., nov. 14
American Airlines Logo
6:15 pm - 11:53 pmLSE-CLT
4h 38m1 stop
American Airlines Logo
6:00 pm - 11:49 pmCLT-LSE
6h 49m1 stop
$578American Airlines
Find Deal
mar., oct. 7 - dom., nov. 2

American Airlines flights from La Crosse to South Carolina

Our best American Airlines deals on La Crosse to South Carolina flight tickets
American Airlines
Oct 14
LSE6:15 pmLa Crosse
4h 38m
1 stop
CLT11:53 pmCharlotte Douglas
Nov 14
CLT6:08 pmCharlotte Douglas
6h 41m
1 stop
LSE11:49 pmLa Crosse
$458
Find similar
American Airlines
Oct 14
LSE10:54 amLa Crosse
7h 25m
2 stops
CLT7:19 pmCharlotte Douglas
Nov 14
CLT11:18 amCharlotte Douglas
7h 14m
1 stop
LSE5:32 pmLa Crosse
$464
Find similar
American Airlines
Oct 7
LSE6:00 amLa Crosse
5h 35m
1 stop
CLT12:35 pmCharlotte Douglas
Nov 2
CLT11:30 amCharlotte Douglas
7h 02m
1 stop
LSE5:32 pmLa Crosse
$475
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 25, 2025.
Use the filters below to find and compare flights from La Crosse to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/14

6:15 pm-11:53 pm

1 stop4h 38m

Charlotte Douglas

vie. 11/14

6:08 pm-11:49 pm

1 stop6h 41m

$458

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/14

10:54 am-7:19 pm

2 stops7h 25m

Charlotte Douglas

vie. 11/14

11:18 am-5:32 pm

1 stop7h 14m

$464

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/7

6:00 am-12:35 pm

1 stop5h 35m

Charlotte Douglas

dom. 11/2

11:30 am-5:32 pm

1 stop7h 02m

$475

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/14

6:15 pm-11:53 pm

1 stop4h 38m

Charlotte Douglas

vie. 11/14

10:40 am-5:32 pm

2 stops7h 52m

$481

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/14

10:54 am-7:19 pm

2 stops7h 25m

Charlotte Douglas

vie. 11/14

10:40 am-5:32 pm

2 stops7h 52m

$504

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

jue. 10/9

6:00 am-12:23 pm

1 stop5h 23m

Charlotte Douglas

lun. 10/13

6:00 pm-11:26 pm

1 stop6h 26m

$518

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

jue. 10/16

6:15 pm-12:15 am

1 stop5h 00m

Charleston

lun. 10/20

7:45 pm-11:26 pm

1 stop4h 41m

$548

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

jue. 10/16

6:15 pm-12:15 am

1 stop5h 00m

Charleston

lun. 10/20

6:36 pm-11:26 pm

2 stops5h 50m

$554

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/14

10:54 am-7:19 pm

2 stops7h 25m

Charlotte Douglas

vie. 11/14

10:40 am-5:32 pm

2 stops7h 52m

$563

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

mar. 10/7

6:15 pm-11:53 pm

1 stop4h 38m

Charlotte Douglas

dom. 11/2

6:00 pm-11:49 pm

1 stop6h 49m

$578

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from La Crosse to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on La Crosse to South Carolina flights?

You could potentially save up to 1% on your flight if you consider stops on a La Crosse to South Carolina flight.

Cheap La Crosse to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to South Carolina

Direct flights

None
There are no direct flights from La Crosse to South Carolina. There are no popular flight routes from La Crosse to South Carolina.
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  • When did momondo last update prices for flights from La Crosse Airport to South Carolina?

    Prices for flights from La Crosse Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from La Crosse Airport to South Carolina?

  • How old do you have to be to fly from La Crosse Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to South Carolina?

Finding the right flight to South Carolina from La Crosse is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from La Crosse to South Carolina with flexible booking policies on momondo?

All flight searches from La Crosse to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from La Crosse to South Carolina?

momondo provides multiple filters to help you find the best flight to South Carolina from La Crosse. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from La Crosse to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from La Crosse and alert you when they change.

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