Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from La Crosse to Indianapolis from $257

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to Indianapolis departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from La Crosse to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:40 am - 3:18 pm
LSE
-
IND
8h 38m
1 stop
American Airlines Logo
8:53 pm - 9:35 am
IND
-
LSE
13h 42m
1 stop
$298American Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
6:37 pm - 1:10 pm
LSE
-
IND
17h 33m
1 stop
American Airlines Logo
9:40 am - 11:54 pm
IND
-
LSE
15h 14m
1 stop
$346American Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
5:40 am - 3:18 pm
LSE
-
IND
8h 38m
1 stop
American Airlines Logo
1:50 pm - 11:54 pm
IND
-
LSE
11h 04m
1 stop
$358American Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
5:40 am - 5:08 pm
LSE
-
IND
10h 28m
2 stops
American Airlines Logo
5:55 am - 6:07 pm
IND
-
LSE
13h 12m
1 stop
$394American Airlines
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
6:37 pm - 1:10 pm
LSE
-
IND
17h 33m
1 stop
American Airlines Logo
8:53 pm - 9:35 am
IND
-
LSE
13h 42m
1 stop
$406American Airlines
Tue, Apr 7 - Fri, Apr 10
American Airlines Logo
5:40 am - 5:08 pm
LSE
-
IND
10h 28m
2 stops
American Airlines Logo
8:53 pm - 9:35 am
IND
-
LSE
13h 42m
1 stop
$450American Airlines
Tue, Apr 7 - Fri, Apr 10
American Airlines Logo
5:40 am - 4:43 pm
LSE
-
IND
10h 03m
2 stops
American Airlines Logo
1:50 pm - 11:54 pm
IND
-
LSE
11h 04m
1 stop
$480American Airlines
Thu, Apr 23 - Sun, Apr 26
American Airlines Logo
10:05 am - 3:18 pm
LSE
-
IND
4h 13m
1 stop
American Airlines Logo
7:43 pm - 11:54 pm
IND
-
LSE
5h 11m
1 stop
$488American Airlines
Fri, Apr 24 - Sun, Apr 26
American Airlines Logo
10:05 am - 7:18 pm
LSE
-
IND
8h 13m
2 stops
American Airlines Logo
3:48 pm - 11:54 pm
IND
-
LSE
9h 06m
1 stop
$489American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
9:48 am - 4:58 pm
LSE
-
IND
6h 10m
1 stop
American Airlines Logo
7:00 am - 11:02 am
IND
-
LSE
5h 02m
1 stop
$494American Airlines
Tue, Mar 17 - Sat, Mar 21

American Airlines flights from La Crosse to Indianapolis

Our best American Airlines deals on La Crosse to Indianapolis flight tickets
American Airlines
Apr 21
LSE5:40 amLa Crosse
8h 38m
1 stop
IND3:18 pmIndianapolis
Apr 25
IND8:53 pmIndianapolis
13h 42m
1 stop
LSE9:35 amLa Crosse
$298
American Airlines
Apr 21
LSE6:37 pmLa Crosse
17h 33m
1 stop
IND1:10 pmIndianapolis
Apr 25
IND9:40 amIndianapolis
15h 14m
1 stop
LSE11:54 pmLa Crosse
$346
American Airlines
Apr 21
LSE5:40 amLa Crosse
8h 38m
1 stop
IND3:18 pmIndianapolis
Apr 25
IND1:50 pmIndianapolis
11h 04m
1 stop
LSE11:54 pmLa Crosse
$358

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from La Crosse to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/21

5:40 am-3:18 pm

1 stop8h 38m

Indianapolis

Sat 4/25

8:53 pm-9:35 am

1 stop13h 42m

$298

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/21

6:37 pm-1:10 pm

1 stop17h 33m

Indianapolis

Sat 4/25

9:40 am-11:54 pm

1 stop15h 14m

$346

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/21

5:40 am-3:18 pm

1 stop8h 38m

Indianapolis

Sat 4/25

1:50 pm-11:54 pm

1 stop11h 04m

$358

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/21

5:40 am-5:08 pm

2 stops10h 28m

Indianapolis

Sat 4/25

5:55 am-6:07 pm

1 stop13h 12m

$394

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/7

6:37 pm-1:10 pm

1 stop17h 33m

Indianapolis

Fri 4/10

8:53 pm-9:35 am

1 stop13h 42m

$406

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/7

5:40 am-5:08 pm

2 stops10h 28m

Indianapolis

Fri 4/10

8:53 pm-9:35 am

1 stop13h 42m

$450

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Thu 4/23

5:40 am-4:43 pm

2 stops10h 03m

Indianapolis

Sun 4/26

1:50 pm-11:54 pm

1 stop11h 04m

$480

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Fri 4/24

10:05 am-3:18 pm

1 stop4h 13m

Indianapolis

Sun 4/26

7:43 pm-11:54 pm

1 stop5h 11m

$488

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Fri 4/24

10:05 am-7:18 pm

2 stops8h 13m

Indianapolis

Mon 4/27

3:48 pm-11:54 pm

1 stop9h 06m

$489

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 3/17

9:48 am-4:58 pm

1 stop6h 10m

Indianapolis

Sat 3/21

7:00 am-11:02 am

1 stop5h 02m

$494

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

See travel insights to Indianapolis from

How to get the cheapest flight ticket from La Crosse to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from La Crosse to Indianapolis?

American Airlines is the most popular carrier operating from La Crosse to Indianapolis

What airlines fly to Indianapolis?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Indianapolis from La Crosse according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Indianapolis. Keep in mind that there are 3 different airlines that fly to Indianapolis on a routine basis, so you have a few additional options to choose from.

When to book flights from La Crosse to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to Indianapolis (LSE to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to Indianapolis

Fastest flight time

6h 10m

Direct flights

None
The fastest flight from La Crosse to Indianapolis takes 6h 10m
There are no direct flights from La Crosse to Indianapolis. There are no popular flight routes from La Crosse to Indianapolis.
Search flight deals

  • How far is La Crosse to Indianapolis by plane?

    The straight-line distance from La Crosse to Indianapolis is 381.9 mi. Typically, this will take 6h 10m by plane in normal conditions.

  • When did momondo last update prices for flights from La Crosse Airport to Indianapolis Airport?

    Prices for flights from La Crosse Airport to Indianapolis Airport are updated daily.

  • How old do you have to be to fly from La Crosse Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The necessary travel and health documents for your Indianapolis Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Carmel
Fishers
Shelbyville
Franklin
West Lafayette
Seymour
Brownsburg
Speedway
Crawfordsville
Westfield
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to Indianapolis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from La Crosse to Indianapolis. momondo saves you time and could save you money on your trip.

Can I find flights from La Crosse to Indianapolis with flexible booking policies on momondo?

All flight searches from La Crosse to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from La Crosse to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from La Crosse.

I’m not ready to book a flight from La Crosse to Indianapolis right now. Can momondo alert me if prices change?

Price alerts on flights to Indianapolis from La Crosse are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Indianapolis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 4/2
Thu 4/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States