What is the cheapest airline that flies from Knoxville McGhee Tyson to Syracuse Hancock Intl?

Allegiant Air and Delta are the most popular carriers operating from Knoxville McGhee Tyson to Syracuse Hancock Intl

What airlines fly to Syracuse?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Syracuse from Knoxville according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Syracuse. Keep in mind that there are 3 different airlines that fly to Syracuse on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport?

There are 2 operators available for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport as of May 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport.

What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?

The required travel and health documents for your Syracuse Hancock Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Syracuse Hancock Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$189 Cheap Flights from Knoxville to Syracuse in 2026

Q: What is the typical price of a round-trip flight between Knoxville and Syracuse?

Prices are currently low for flights on this route. Typical prices usually range from $409 to $353. The lowest price recently found on this route was $234.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Knoxville to Syracuse

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:02 pm - 6:36 pm

TYS

SYR

29h 34m

1 stop

7:25 pm - 9:57 am

SYR

TYS

14h 32m

1 stop

$234Allegiant Air

Wed, Jun 10 - Fri, Jun 12

1:36 pm - 7:51 pm

TYS

SYR

6h 15m

1 stop

7:26 pm - 8:36 am

SYR

TYS

13h 10m

1 stop

$272Allegiant Air

Fri, Aug 14 - Sun, Aug 16

6:13 am - 10:26 am

TYS

SYR

4h 13m

1 stop

5:48 am - 10:15 am

SYR

TYS

4h 27m

1 stop

$293American Airlines

Thu, Sep 3 - Wed, Sep 9

6:07 pm - 10:48 pm

TYS

SYR

4h 41m

1 stop

6:05 am - 11:04 am

SYR

TYS

4h 59m

1 stop

$308Delta

Fri, May 29 - Sun, May 31

5:25 pm - 10:57 pm

TYS

SYR

5h 32m

1 stop

6:00 am - 11:01 am

SYR

TYS

5h 01m

1 stop

$309Delta

Wed, Jun 10 - Sun, Jun 14

6:07 pm - 10:48 pm

TYS

SYR

4h 41m

1 stop

6:54 pm - 11:52 pm

SYR

TYS

4h 58m

1 stop

$324Delta

Mon, Jun 1 - Thu, Jul 9

7:30 am - 7:22 pm

TYS

SYR

11h 52m

2 stops

7:26 pm - 8:36 am

SYR

TYS

13h 10m

1 stop

$338Multiple Airlines

Fri, Aug 14 - Sun, Aug 16

6:07 pm - 10:48 pm

TYS

SYR

4h 41m

1 stop

6:00 am - 11:05 am

SYR

TYS

5h 05m

1 stop

$339Delta

Mon, Jun 1 - Wed, Jul 8

8:00 am - 7:22 pm

TYS

SYR

11h 22m

1 stop

7:31 pm - 9:56 pm

SYR

TYS

26h 25m

1 stop

$347Multiple Airlines

Mon, Jun 1 - Fri, Jul 10

7:19 pm - 11:59 pm

TYS

SYR

4h 40m

1 stop

6:00 am - 10:42 am

SYR

TYS

4h 42m

1 stop

$350United Airlines

Mon, Jun 15 - Sun, Jun 21

American Airlines flights from Knoxville to Syracuse

Our best American Airlines deals on Knoxville to Syracuse flight tickets

American Airlines

Sep 3

TYS6:13 amKnoxville McGhee Tyson

4h 13m

1 stop

SYR10:26 amSyracuse Hancock Intl

Sep 9

SYR5:48 amSyracuse Hancock Intl

4h 27m

1 stop

TYS10:15 amKnoxville McGhee Tyson

$293

American Airlines

Jun 1

TYS6:53 pmKnoxville McGhee Tyson

5h 27m

1 stop

SYR12:20 amSyracuse Hancock Intl

Jul 2

SYR7:34 pmSyracuse Hancock Intl

4h 17m

1 stop

TYS11:51 pmKnoxville McGhee Tyson

$355

American Airlines

Jun 5

TYS6:53 pmKnoxville McGhee Tyson

5h 27m

1 stop

SYR12:20 amSyracuse Hancock Intl

Jun 9

SYR6:08 amSyracuse Hancock Intl

6h 27m

2 stops

TYS12:35 pmKnoxville McGhee Tyson

$370

Delta flights from Knoxville to Syracuse

Our best Delta deals on Knoxville to Syracuse flight tickets

Delta

May 29

TYS6:07 pmKnoxville McGhee Tyson

4h 41m

1 stop

SYR10:48 pmSyracuse Hancock Intl

May 31

SYR6:05 amSyracuse Hancock Intl

4h 59m

1 stop

TYS11:04 amKnoxville McGhee Tyson

$308

Delta

Jun 10

TYS5:25 pmKnoxville McGhee Tyson

5h 32m

1 stop

SYR10:57 pmSyracuse Hancock Intl

Jun 14

SYR6:00 amSyracuse Hancock Intl

5h 01m

1 stop

TYS11:01 amKnoxville McGhee Tyson

$309

Delta

Jun 1

TYS6:07 pmKnoxville McGhee Tyson

4h 41m

1 stop

SYR10:48 pmSyracuse Hancock Intl

Jul 9

SYR6:54 pmSyracuse Hancock Intl

4h 58m

1 stop

TYS11:52 pmKnoxville McGhee Tyson

$324

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Wed 6/10

1:02 pm-6:36 pm

1 stop29h 34m

Syracuse Hancock Intl

Fri 6/12

7:25 pm-9:57 am

1 stop14h 32m

$234

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 8/14

1:36 pm-7:51 pm

1 stop6h 15m

Syracuse Hancock Intl

Sun 8/16

7:26 pm-8:36 am

1 stop13h 10m

$272

Quickest round-trip

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 9/3

6:13 am-10:26 am

1 stop4h 13m

Syracuse Hancock Intl

Wed 9/9

5:48 am-10:15 am

1 stop4h 27m

$293

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 5/29

6:07 pm-10:48 pm

1 stop4h 41m

Syracuse Hancock Intl

Sun 5/31

6:05 am-11:04 am

1 stop4h 59m

$308

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Wed 6/10

5:25 pm-10:57 pm

1 stop5h 32m

Syracuse Hancock Intl

Sun 6/14

6:00 am-11:01 am

1 stop5h 01m

$309

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Mon 6/1

6:07 pm-10:48 pm

1 stop4h 41m

Syracuse Hancock Intl

Thu 7/9

6:54 pm-11:52 pm

1 stop4h 58m

$324

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 8/14

7:30 am-7:22 pm

2 stops11h 52m

Syracuse Hancock Intl

Sun 8/16

7:26 pm-8:36 am

1 stop13h 10m

$338

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Mon 6/1

6:07 pm-10:48 pm

1 stop4h 41m

Syracuse Hancock Intl

Wed 7/8

6:00 am-11:05 am

1 stop5h 05m

$339

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Mon 6/1

8:00 am-7:22 pm

1 stop11h 22m

Syracuse Hancock Intl

Fri 7/10

7:31 pm-9:56 pm

1 stop26h 25m

$347

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Mon 6/15

7:19 pm-11:59 pm

1 stop4h 40m

Syracuse Hancock Intl

Sun 6/21

6:00 am-10:42 am

1 stop4h 42m

$350

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Syracuse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Knoxville and Syracuse?

What is the cheapest month to fly to Syracuse?

The month of December is, on average, the cheapest month to fly to Syracuse from Knoxville, with most prices found around $248. If you aren’t able to travel to Syracuse during the month of December, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $288.

When to book flights from Knoxville to Syracuse

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Syracuse according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Syracuse (TYS to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Syracuse

Fastest flight time	4h 38m
Direct flights	None

The fastest flight from Knoxville to Syracuse takes 4h 38m

There are no direct flights from Knoxville to Syracuse. There are no popular flight routes from Knoxville to Syracuse.

Search flight deals

Frequently asked questions about flying from Knoxville to Syracuse

How far is Knoxville McGhee Tyson to Syracuse Hancock Intl by plane?
The distance between Knoxville McGhee Tyson and Syracuse Hancock Intl is about 640.5 mi. Flights usually cover this in 4h 38m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport?
There are 2 operators available for flights from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport as of May 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Syracuse Hancock Intl Airport.
What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?
The required travel and health documents for your Syracuse Hancock Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Syracuse Hancock Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Syracuse?
Based on momondo bookings for flights between Knoxville and Syracuse, the leading airline is American Airlines, making up 65% of the total bookings. Other popular airlines include Delta with 35%.

Best airlines flying from Knoxville to Syracuse

Compare and see reviews for airlines that fly from Knoxville to Syracuse with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,648 reviews		Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,447 reviews		Search Delta flights

Skaneateles

Liverpool

Oswego

East Syracuse

Waterloo

Auburn

Seneca Falls

Cicero

Bridgeport

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Syracuse?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Syracuse. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Syracuse with flexible booking policies on momondo?

Flights from Knoxville to Syracuse with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Syracuse?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Syracuse from Knoxville.

I’m not ready to book a flight from Knoxville to Syracuse right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Syracuse now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Syracuse and let you know when they change.

An easier way to manage your Syracuse trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Wed 6/17

Wed 6/24

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Knoxville

Complete your trip

Feeling lucky

Cheap flights from Knoxville to Syracuse from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Syracuse departing on 6/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Knoxville to Syracuse

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

American Airlines flights from Knoxville to Syracuse

Our best American Airlines deals on Knoxville to Syracuse flight tickets

Delta flights from Knoxville to Syracuse

Our best Delta deals on Knoxville to Syracuse flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.

See travel insights to Syracuse from

How to get the cheapest flight ticket from Knoxville to Syracuse

What is the typical price of a round-trip flight between Knoxville and Syracuse?

What is the cheapest month to fly to Syracuse?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Syracuse Hancock Intl?

What airlines fly to Syracuse?

When to book flights from Knoxville to Syracuse

Cheap Knoxville to Syracuse (TYS to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Syracuse

Fastest flight time

Direct flights

Frequently asked questions about flying from Knoxville to Syracuse

Best airlines flying from Knoxville to Syracuse

Compare and see reviews for airlines that fly from Knoxville to Syracuse with momondo

Traveling to a place near Syracuse?

Why use momondo?

An easier way to manage your Syracuse trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing New York

Fly your favorite airline to Syracuse

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Syracuse

List of cabin classes available on flights landing in Syracuse. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Knoxville

According to popular flight searches on momondo this year

Complete your trip to Syracuse

Explore popular destinations other users love

According to popular flight searches on momondo this year