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Cheap flights from Knoxville to Guadalajara from $192

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guadalajara departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to Guadalajara

Cheap round-trip flights

Multiple Airlines Logo
7:00 am - 3:05 pmTYS-GDL
10h 05m1 stop
Multiple Airlines Logo
6:36 am - 7:32 pmGDL-TYS
10h 56m1 stop
$446Multiple Airlines
Find Deal
Thu, Oct 9 - Sun, Oct 19
Multiple Airlines Logo
8:17 pm - 3:05 pmTYS-GDL
20h 48m1 stop
Multiple Airlines Logo
10:20 am - 9:07 pmGDL-TYS
32h 47m2 stops
$460Multiple Airlines
Find Deal
Fri, Oct 17 - Wed, Oct 22
American Airlines Logo
6:22 pm - 10:41 pmTYS-GDL
6h 19m1 stop
American Airlines Logo
7:00 am - 5:32 pmGDL-TYS
8h 32m1 stop
$505American Airlines
Find Deal
Fri, Oct 10 - Fri, Oct 17
American Airlines Logo
6:00 am - 9:55 amTYS-GDL
5h 55m1 stop
American Airlines Logo
7:00 am - 12:23 amGDL-TYS
15h 23m1 stop
$537American Airlines
Find Deal
Tue, Oct 7 - Sat, Oct 18
Aeromexico Logo
3:48 pm - 8:30 amTYS-GDL
18h 42m2 stops
Aeromexico Logo
9:23 am - 11:07 pmGDL-TYS
11h 44m2 stops
$585Aeromexico
Find Deal
Fri, Oct 17 - Tue, Oct 21
Delta Logo
5:44 am - 4:38 pmTYS-GDL
12h 54m2 stops
Delta Logo
9:23 am - 11:46 pmGDL-TYS
12h 23m2 stops
$605Delta
Find Deal
Fri, Oct 10 - Fri, Oct 17
United Airlines Logo
7:00 am - 9:35 pmTYS-GDL
16h 35m1 stop
United Airlines Logo
12:35 pm - 11:19 pmGDL-TYS
8h 44m1 stop
$620United Airlines
Find Deal
Mon, Mar 9 - Wed, Mar 11
United Airlines Logo
9:15 am - 9:35 pmTYS-GDL
14h 20m1 stop
United Airlines Logo
2:22 pm - 1:18 pmGDL-TYS
20h 56m2 stops
$625United Airlines
Find Deal
Mon, Mar 9 - Wed, Mar 11
Aeromexico Logo
7:11 am - 8:30 amTYS-GDL
27h 19m2 stops
Aeromexico Logo
5:48 am - 7:05 pmGDL-TYS
11h 17m2 stops
$679Aeromexico
Find Deal
Fri, Oct 17 - Fri, Oct 24
Delta Logo
6:40 am - 6:35 pmTYS-GDL
13h 55m2 stops
Delta Logo
9:23 am - 11:46 pmGDL-TYS
12h 23m2 stops
$785Delta
Find Deal
Thu, Oct 9 - Sun, Oct 19

American Airlines flights from Knoxville to Guadalajara

Our best American Airlines deals on Knoxville to Guadalajara flight tickets
American Airlines
Oct 10
TYS6:22 pmKnoxville McGhee Tyson
6h 19m
1 stop
GDL10:41 pmGuadalajara Miguel Hidal
Oct 17
GDL7:00 amGuadalajara Miguel Hidal
8h 32m
1 stop
TYS5:32 pmKnoxville McGhee Tyson
$505
Find similar
American Airlines
Oct 7
TYS6:00 amKnoxville McGhee Tyson
5h 55m
1 stop
GDL9:55 amGuadalajara Miguel Hidal
Oct 18
GDL7:00 amGuadalajara Miguel Hidal
15h 23m
1 stop
TYS12:23 amKnoxville McGhee Tyson
$537
Find similar
American Airlines
Jan 10
TYS6:30 pmKnoxville McGhee Tyson
6h 00m
1 stop
GDL11:30 pmGuadalajara Miguel Hidal
Jan 17
GDL12:35 pmGuadalajara Miguel Hidal
10h 51m
1 stop
TYS12:26 amKnoxville McGhee Tyson
$550
Find similar

United Airlines flights from Knoxville to Guadalajara

Our best United Airlines deals on Knoxville to Guadalajara flight tickets
United Airlines
Mar 9
TYS7:00 amKnoxville McGhee Tyson
16h 35m
1 stop
GDL9:35 pmGuadalajara Miguel Hidal
Mar 11
GDL12:35 pmGuadalajara Miguel Hidal
8h 44m
1 stop
TYS11:19 pmKnoxville McGhee Tyson
$620
Find similar
United Airlines
Mar 9
TYS9:15 amKnoxville McGhee Tyson
14h 20m
1 stop
GDL9:35 pmGuadalajara Miguel Hidal
Mar 11
GDL2:22 pmGuadalajara Miguel Hidal
20h 56m
2 stops
TYS1:18 pmKnoxville McGhee Tyson
$625
Find similar
United Airlines
Oct 8
TYS7:26 pmKnoxville McGhee Tyson
20h 08m
2 stops
GDL1:34 pmGuadalajara Miguel Hidal
Oct 11
GDL2:30 pmGuadalajara Miguel Hidal
20h 55m
2 stops
TYS1:25 pmKnoxville McGhee Tyson
$640
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Knoxville to Guadalajara that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 10/9

7:00 am-3:05 pm

1 stop10h 05m

Guadalajara Miguel Hidal

Sun 10/19

6:36 am-7:32 pm

1 stop10h 56m

$446

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Fri 10/17

8:17 pm-3:05 pm

1 stop20h 48m

Guadalajara Miguel Hidal

Wed 10/22

10:20 am-9:07 pm

2 stops32h 47m

$460

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Fri 10/10

6:22 pm-10:41 pm

1 stop6h 19m

Guadalajara Miguel Hidal

Fri 10/17

7:00 am-5:32 pm

1 stop8h 32m

$505

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Tue 10/7

6:00 am-9:55 am

1 stop5h 55m

Guadalajara Miguel Hidal

Sat 10/18

7:00 am-12:23 am

1 stop15h 23m

$537

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Fri 10/17

3:48 pm-8:30 am

2 stops18h 42m

Guadalajara Miguel Hidal

Tue 10/21

9:23 am-11:07 pm

2 stops11h 44m

$585

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Fri 10/10

5:44 am-4:38 pm

2 stops12h 54m

Guadalajara Miguel Hidal

Fri 10/17

9:23 am-11:46 pm

2 stops12h 23m

$605

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Mon 3/9

7:00 am-9:35 pm

1 stop16h 35m

Guadalajara Miguel Hidal

Wed 3/11

12:35 pm-11:19 pm

1 stop8h 44m

$620

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Mon 3/9

9:15 am-9:35 pm

1 stop14h 20m

Guadalajara Miguel Hidal

Wed 3/11

2:22 pm-1:18 pm

2 stops20h 56m

$625

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Fri 10/17

7:11 am-8:30 am

2 stops27h 19m

Guadalajara Miguel Hidal

Fri 10/24

5:48 am-7:05 pm

2 stops11h 17m

$679

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 10/9

6:40 am-6:35 pm

2 stops13h 55m

Guadalajara Miguel Hidal

Sun 10/19

9:23 am-11:46 pm

2 stops12h 23m

$785

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guadalajara from

How to get the cheapest flight ticket from Knoxville to Guadalajara

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guadalajara?

Our data shows that Wednesday is the least expensive day to fly to Guadalajara. Tickets to fly out on this day can be as low as $588. Flights from Knoxville to Guadalajara on a Monday will generally be more expensive and average around $722. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Guadalajara?

Flying to Guadalajara from Knoxville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $655 when looking at flights departing in the morning. In contrast, the most expensive time of day to depart to Guadalajara is in the afternoon when prices are around $949.

When to book flights from Knoxville to Guadalajara

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Guadalajara according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Guadalajara (TYS to GDL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guadalajara

Direct flights

None
There are no direct flights from Knoxville to Guadalajara. There are no popular flight routes from Knoxville to Guadalajara.
Search flight deals

  • How far is Knoxville McGhee Tyson to Guadalajara Miguel Hidal by plane?

    The straight-line distance from Knoxville McGhee Tyson to Guadalajara Miguel Hidal is 1578.5 mi. By plane, this route typically takes 5h 55m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guadalajara Miguel Hidal Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Guadalajara Miguel Hidal Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guadalajara Miguel Hidal Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guadalajara Miguel Hidal Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guadalajara Miguel Hidal Airport.

  • What documentation or ID do you need to fly to Guadalajara Miguel Hidal Airport?

    The travel and health documents you'll need for your trip to Guadalajara Miguel Hidal Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Guadalajara Miguel Hidal Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Guadalajara?

Best airlines flying from Knoxville to Guadalajara

Compare and see reviews for airlines that fly from Knoxville to Guadalajara with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $467Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tequila
Ajijic
Zapopan
Tlaquepaque

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guadalajara?

Finding the right flight to Guadalajara from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Guadalajara quick and easy, saving you time and money.

Can I find flights from Knoxville to Guadalajara with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Guadalajara flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Guadalajara?

momondo provides multiple filters to help you find the best flight to Guadalajara from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Guadalajara right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Guadalajara flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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