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Cheap flights from Knoxville to Columbia from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Columbia departing on 12/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:40 am - 9:28 am
TYS
-
CAE
3h 48m1 stop
Delta Logo
2:58 pm - 6:52 pm
CAE
-
TYS
3h 54m1 stop
$327Delta
Tue, Jan 6 - Tue, Jan 13
United Airlines Logo
9:30 am - 6:55 pm
TYS
-
CAE
9h 25m1 stop
United Airlines Logo
7:30 pm - 10:57 am
CAE
-
TYS
15h 27m1 stop
$487United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
9:30 am - 6:55 pm
TYS
-
CAE
9h 25m1 stop
United Airlines Logo
7:30 pm - 8:52 pm
CAE
-
TYS
25h 22m2 stops
$507United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
11:07 am - 11:44 pm
TYS
-
CAE
12h 37m2 stops
United Airlines Logo
7:30 pm - 8:52 pm
CAE
-
TYS
25h 22m2 stops
$528United Airlines
Sat, Jan 31 - Tue, Feb 3
American Airlines Logo
8:30 am - 2:10 pm
TYS
-
CAE
5h 40m1 stop
American Airlines Logo
5:07 am - 8:56 am
CAE
-
TYS
3h 49m1 stop
$549American Airlines
Thu, Dec 25 - Mon, Dec 29
United Airlines Logo
2:25 pm - 10:17 am
TYS
-
CAE
19h 52m1 stop
United Airlines Logo
7:30 pm - 7:27 pm
CAE
-
TYS
23h 57m1 stop
$555United Airlines
Fri, Jan 9 - Fri, Jan 16
United Airlines Logo
7:20 pm - 10:17 am
TYS
-
CAE
14h 57m1 stop
United Airlines Logo
7:30 pm - 10:32 am
CAE
-
TYS
15h 02m2 stops
$575United Airlines
Fri, Jan 9 - Fri, Jan 16
United Airlines Logo
5:29 pm - 11:44 pm
TYS
-
CAE
30h 15m2 stops
United Airlines Logo
7:30 pm - 1:24 pm
CAE
-
TYS
17h 54m2 stops
$613United Airlines
Fri, Jan 9 - Fri, Jan 16
United Airlines Logo
6:45 am - 12:26 am
TYS
-
CAE
17h 41m1 stop
United Airlines Logo
10:40 am - 11:59 pm
CAE
-
TYS
13h 19m1 stop
$627United Airlines
Thu, Dec 25 - Mon, Dec 29
United Airlines Logo
6:45 am - 12:26 am
TYS
-
CAE
17h 41m1 stop
United Airlines Logo
7:37 pm - 10:39 pm
CAE
-
TYS
27h 02m2 stops
$657United Airlines
Thu, Dec 25 - Mon, Dec 29

American Airlines flights from Knoxville to Columbia

Our best American Airlines deals on Knoxville to Columbia flight tickets
American Airlines
Dec 25
TYS8:30 amKnoxville McGhee Tyson
5h 40m
1 stop
CAE2:10 pmColumbia Metropolitan
Dec 29
CAE5:07 amColumbia Metropolitan
3h 49m
1 stop
TYS8:56 amKnoxville McGhee Tyson
$549
Find similar
American Airlines
Dec 24
TYS7:00 amKnoxville McGhee Tyson
8h 47m
2 stops
CAE3:47 pmColumbia Metropolitan
Dec 28
CAE11:07 amColumbia Metropolitan
5h 37m
1 stop
TYS4:44 pmKnoxville McGhee Tyson
$773
Find similar

United Airlines flights from Knoxville to Columbia

Our best United Airlines deals on Knoxville to Columbia flight tickets
United Airlines
Jan 31
TYS9:30 amKnoxville McGhee Tyson
9h 25m
1 stop
CAE6:55 pmColumbia Metropolitan
Feb 3
CAE7:30 pmColumbia Metropolitan
15h 27m
1 stop
TYS10:57 amKnoxville McGhee Tyson
$487
Find similar
United Airlines
Jan 31
TYS9:30 amKnoxville McGhee Tyson
9h 25m
1 stop
CAE6:55 pmColumbia Metropolitan
Feb 3
CAE7:30 pmColumbia Metropolitan
25h 22m
2 stops
TYS8:52 pmKnoxville McGhee Tyson
$507
Find similar
United Airlines
Jan 31
TYS11:07 amKnoxville McGhee Tyson
12h 37m
2 stops
CAE11:44 pmColumbia Metropolitan
Feb 3
CAE7:30 pmColumbia Metropolitan
25h 22m
2 stops
TYS8:52 pmKnoxville McGhee Tyson
$528
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Knoxville to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Tue 1/6

5:40 am-9:28 am

1 stop3h 48m

Columbia Metropolitan

Tue 1/13

2:58 pm-6:52 pm

1 stop3h 54m

$327

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 1/31

9:30 am-6:55 pm

1 stop9h 25m

Columbia Metropolitan

Tue 2/3

7:30 pm-10:57 am

1 stop15h 27m

$487

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 1/31

9:30 am-6:55 pm

1 stop9h 25m

Columbia Metropolitan

Tue 2/3

7:30 pm-8:52 pm

2 stops25h 22m

$507

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 1/31

11:07 am-11:44 pm

2 stops12h 37m

Columbia Metropolitan

Tue 2/3

7:30 pm-8:52 pm

2 stops25h 22m

$528

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 12/25

8:30 am-2:10 pm

1 stop5h 40m

Columbia Metropolitan

Mon 12/29

5:07 am-8:56 am

1 stop3h 49m

$549

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 1/9

2:25 pm-10:17 am

1 stop19h 52m

Columbia Metropolitan

Fri 1/16

7:30 pm-7:27 pm

1 stop23h 57m

$555

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 1/9

7:20 pm-10:17 am

1 stop14h 57m

Columbia Metropolitan

Fri 1/16

7:30 pm-10:32 am

2 stops15h 02m

$575

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 1/9

5:29 pm-11:44 pm

2 stops30h 15m

Columbia Metropolitan

Fri 1/16

7:30 pm-1:24 pm

2 stops17h 54m

$613

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 12/25

6:45 am-12:26 am

1 stop17h 41m

Columbia Metropolitan

Mon 12/29

10:40 am-11:59 pm

1 stop13h 19m

$627

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 12/25

6:45 am-12:26 am

1 stop17h 41m

Columbia Metropolitan

Mon 12/29

7:37 pm-10:39 pm

2 stops27h 02m

$657

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Columbia?

In the morning is the cheapest time of day to fly from Knoxville to Columbia when you can find flight prices for as low as $507. Flying to Columbia in the morning is an ideal time because this is during off-peak travel hours. Flights in the afternoon are often more expensive with an average ticket price of $525.

When to book flights from Knoxville to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Columbia (TYS to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Columbia

Fastest flight time

9h 25m

Direct flights

None
The fastest flight from Knoxville to Columbia takes 9h 25m
There are no direct flights from Knoxville to Columbia. There are no popular flight routes from Knoxville to Columbia.
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  • How far is Knoxville McGhee Tyson to Columbia Metropolitan by plane?

    A flight from Knoxville McGhee Tyson to Columbia Metropolitan will travel around 212.0 mi. 9h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The travel and health documents you'll need for your trip to Columbia Metropolitan Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Metropolitan Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Columbia?

Best airlines flying from Knoxville to Columbia

Compare and see reviews for airlines that fly from Knoxville to Columbia with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $286Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Columbia for you.

Can I find flights from Knoxville to Columbia with flexible booking policies on momondo?

Flights from Knoxville to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Columbia?

Once all potential Knoxville to Columbia flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Columbia right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Columbia, momondo offers a useful price alert feature which will track prices for flights to Columbia from Knoxville and alert you when they change.

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