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Cheap flights from Knoxville to Columbia from $297

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Columbia departing on 9/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Columbia

Cheap round-trip flights

Delta Logo
8:35 am - 12:19 pmTYS-CAE
3h 44m1 stop
Delta Logo
5:40 am - 10:42 amCAE-TYS
5h 02m1 stop
$297Delta
Find Deal
Sat, Sep 6 - Tue, Sep 9
Delta Logo
5:45 am - 10:00 amTYS-CAE
4h 15m1 stop
Delta Logo
3:08 pm - 8:06 pmCAE-TYS
4h 58m1 stop
$425Delta
Find Deal
Sat, Aug 16 - Tue, Aug 19
Delta Logo
10:40 am - 2:23 pmTYS-CAE
3h 43m1 stop
Delta Logo
9:56 am - 1:08 pmCAE-TYS
3h 12m1 stop
$436Delta
Find Deal
Thu, Aug 14 - Tue, Aug 19
American Airlines Logo
10:36 am - 7:02 pmTYS-CAE
8h 26m1 stop
American Airlines Logo
6:00 am - 4:57 pmCAE-TYS
10h 57m1 stop
$437American Airlines
Find Deal
Fri, Aug 15 - Mon, Aug 18
American Airlines Logo
8:25 pm - 11:59 pmTYS-CAE
3h 34m1 stop
American Airlines Logo
4:18 pm - 7:45 pmCAE-TYS
3h 27m1 stop
$450American Airlines
Find Deal
Sat, Aug 16 - Sun, Aug 17
American Airlines Logo
11:15 am - 2:06 pmTYS-CAE
2h 51m1 stop
American Airlines Logo
5:55 pm - 10:59 pmCAE-TYS
5h 04m1 stop
$457American Airlines
Find Deal
Thu, Aug 14 - Mon, Aug 18
American Airlines Logo
7:45 pm - 11:07 pmTYS-CAE
3h 22m1 stop
American Airlines Logo
8:05 pm - 11:50 pmCAE-TYS
3h 45m1 stop
$501American Airlines
Find Deal
Sat, Oct 4 - Fri, Oct 10
United Airlines Logo
7:00 am - 6:55 pmTYS-CAE
11h 55m2 stops
United Airlines Logo
7:45 pm - 8:56 pmCAE-TYS
25h 11m1 stop
$602United Airlines
Find Deal
Fri, Aug 15 - Mon, Aug 18
United Airlines Logo
7:00 am - 6:55 pmTYS-CAE
11h 55m2 stops
United Airlines Logo
7:45 pm - 1:25 pmCAE-TYS
17h 40m2 stops
$608United Airlines
Find Deal
Fri, Aug 15 - Mon, Aug 18
United Airlines Logo
7:00 am - 7:01 pmTYS-CAE
12h 01m2 stops
United Airlines Logo
7:48 pm - 2:45 pmCAE-TYS
18h 57m1 stop
$741United Airlines
Find Deal
Sat, Oct 4 - Fri, Oct 10

Delta flights from Knoxville to Columbia

Our best Delta deals on Knoxville to Columbia flight tickets
Delta
Sep 6
TYS8:35 amKnoxville McGhee Tyson
3h 44m
1 stop
CAE12:19 pmColumbia Metropolitan
Sep 9
CAE5:40 amColumbia Metropolitan
5h 02m
1 stop
TYS10:42 amKnoxville McGhee Tyson
$297
Find similar
Delta
Aug 16
TYS5:45 amKnoxville McGhee Tyson
4h 15m
1 stop
CAE10:00 amColumbia Metropolitan
Aug 19
CAE3:08 pmColumbia Metropolitan
4h 58m
1 stop
TYS8:06 pmKnoxville McGhee Tyson
$425
Find similar
Delta
Aug 14
TYS10:40 amKnoxville McGhee Tyson
3h 43m
1 stop
CAE2:23 pmColumbia Metropolitan
Aug 19
CAE9:56 amColumbia Metropolitan
3h 12m
1 stop
TYS1:08 pmKnoxville McGhee Tyson
$436
Find similar

American Airlines flights from Knoxville to Columbia

Our best American Airlines deals on Knoxville to Columbia flight tickets
American Airlines
Aug 15
TYS10:36 amKnoxville McGhee Tyson
8h 26m
1 stop
CAE7:02 pmColumbia Metropolitan
Aug 18
CAE6:00 amColumbia Metropolitan
10h 57m
1 stop
TYS4:57 pmKnoxville McGhee Tyson
$437
Find similar
American Airlines
Aug 16
TYS8:25 pmKnoxville McGhee Tyson
3h 34m
1 stop
CAE11:59 pmColumbia Metropolitan
Aug 17
CAE4:18 pmColumbia Metropolitan
3h 27m
1 stop
TYS7:45 pmKnoxville McGhee Tyson
$450
Find similar
American Airlines
Aug 14
TYS11:15 amKnoxville McGhee Tyson
2h 51m
1 stop
CAE2:06 pmColumbia Metropolitan
Aug 18
CAE5:55 pmColumbia Metropolitan
5h 04m
1 stop
TYS10:59 pmKnoxville McGhee Tyson
$457
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 3, 2025.
Use the filters below to find and compare flights from Knoxville to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 9/6

8:35 am-12:19 pm

1 stop3h 44m

Columbia Metropolitan

Tue 9/9

5:40 am-10:42 am

1 stop5h 02m

$297

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 8/16

5:45 am-10:00 am

1 stop4h 15m

Columbia Metropolitan

Tue 8/19

3:08 pm-8:06 pm

1 stop4h 58m

$425

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 8/14

10:40 am-2:23 pm

1 stop3h 43m

Columbia Metropolitan

Tue 8/19

9:56 am-1:08 pm

1 stop3h 12m

$436

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 8/15

10:36 am-7:02 pm

1 stop8h 26m

Columbia Metropolitan

Mon 8/18

6:00 am-4:57 pm

1 stop10h 57m

$437

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 8/16

8:25 pm-11:59 pm

1 stop3h 34m

Columbia Metropolitan

Sun 8/17

4:18 pm-7:45 pm

1 stop3h 27m

$450

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 8/14

11:15 am-2:06 pm

1 stop2h 51m

Columbia Metropolitan

Mon 8/18

5:55 pm-10:59 pm

1 stop5h 04m

$457

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 10/4

7:45 pm-11:07 pm

1 stop3h 22m

Columbia Metropolitan

Fri 10/10

8:05 pm-11:50 pm

1 stop3h 45m

$501

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 8/15

7:00 am-6:55 pm

2 stops11h 55m

Columbia Metropolitan

Mon 8/18

7:45 pm-8:56 pm

1 stop25h 11m

$602

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 8/15

7:00 am-6:55 pm

2 stops11h 55m

Columbia Metropolitan

Mon 8/18

7:45 pm-1:25 pm

2 stops17h 40m

$608

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Sat 10/4

7:00 am-7:01 pm

2 stops12h 01m

Columbia Metropolitan

Fri 10/10

7:48 pm-2:45 pm

1 stop18h 57m

$741

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Columbia from

How to get the cheapest flight ticket from Knoxville to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Columbia?

In the morning is the cheapest time of day to fly from Knoxville to Columbia when you can find flight prices for as low as $507. Flying to Columbia in the morning is an ideal time because this is during off-peak travel hours. Flights in the afternoon are often more expensive with an average ticket price of $525.

When to book flights from Knoxville to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Columbia (TYS to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Columbia

Best Price Found

$297

Fastest flight time

2h 51m

Direct flights

None

Airports in Columbia

1 airport
The best flight deal from Knoxville to Columbia found on momondo in the last 72 hours is $297
The fastest flight from Knoxville to Columbia takes 2h 51m
There are no direct flights from Knoxville to Columbia. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Columbia Metropolitan Airport.
There is 1 airport near Columbia: Columbia Metropolitan (CAE)
Search flight deals

  • How far is Knoxville McGhee Tyson to Columbia Metropolitan by plane?

    A flight from Knoxville McGhee Tyson to Columbia Metropolitan will travel around 212.0 mi. 2h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The travel and health documents you'll need for your trip to Columbia Metropolitan Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Metropolitan Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Columbia?

Best airlines flying from Knoxville to Columbia

Compare and see reviews for airlines that fly from Knoxville to Columbia with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $286Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $286Free CancellationRating
8.0
7,986 reviews
Search Delta flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Columbia for you.

Can I find flights from Knoxville to Columbia with flexible booking policies on momondo?

Flights from Knoxville to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Columbia?

Once all potential Knoxville to Columbia flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Columbia right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Columbia, momondo offers a useful price alert feature which will track prices for flights to Columbia from Knoxville and alert you when they change.

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