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Cheap flights from Knoxville to Columbia from $273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Columbia departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:00 am - 2:03 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
4h 03m1 stop Charlotte Douglas
American Airlines Logo
7:12 pm - 10:48 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
3h 36m1 stop Charlotte Douglas
$377American Airlines
Thu, Oct 29 - Mon, Nov 2
American Airlines Logo
6:15 am - 9:45 amTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
3h 30m1 stop Charlotte Douglas
American Airlines Logo
5:25 pm - 10:50 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
5h 25m1 stop Charlotte Douglas
$387American Airlines
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
8:12 am - 1:24 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
5h 12m1 stop Charlotte Douglas
American Airlines Logo
4:10 pm - 7:45 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
3h 35m1 stop Charlotte Douglas
$427American Airlines
Sat, Aug 29 - Sat, Sep 5
American Airlines Logo
10:00 am - 3:38 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
5h 38m1 stop Charlotte Douglas
American Airlines Logo
5:00 am - 10:23 amCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
5h 23m1 stop Charlotte Douglas
$442American Airlines
Sat, Oct 24 - Sun, Oct 25
Delta Logo
5:40 am - 11:09 amTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
5h 29m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:44 pm - 11:52 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
6h 08m1 stop Atlanta Hartsfield-Jackson
$457Delta
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
10:00 am - 3:38 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
5h 38m1 stop Charlotte Douglas
American Airlines Logo
5:00 am - 10:23 amCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
5h 23m1 stop Charlotte Douglas
$481American Airlines
Sat, Oct 24 - Sun, Oct 25
American Airlines Logo
7:58 pm - 11:56 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
3h 58m1 stop Charlotte Douglas
American Airlines Logo
8:30 pm - 11:55 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
3h 25m1 stop Charlotte Douglas
$507American Airlines
Fri, Oct 23 - Sun, Oct 25
United Airlines Logo
5:45 am - 2:17 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
8h 32m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
7:54 pm - 9:53 amCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
13h 59m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$611United Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
7:20 pm - 9:47 amTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
14h 27m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
10:22 am - 10:49 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
12h 27m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$634United Airlines
Sat, Sep 12 - Sat, Sep 19
United Airlines Logo
7:20 pm - 7:07 pmTYS  Knoxville McGhee Tyson-CAE Columbia Metropolitan
23h 47m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
7:54 pm - 2:37 pmCAE  Columbia Metropolitan-TYS Knoxville McGhee Tyson
18h 43m1 stop Washington, D.C. Dulles Intl
$642United Airlines
Fri, Aug 28 - Tue, Sep 1

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American Airlines flights from Knoxville to Columbia

Our best American Airlines deals on Knoxville to Columbia flight tickets
American Airlines
Oct 29
TYS10:00 amKnoxville McGhee Tyson
4h 03m
1 stop
CAE2:03 pmColumbia Metropolitan
Nov 2
CAE7:12 pmColumbia Metropolitan
3h 36m
1 stop
TYS10:48 pmKnoxville McGhee Tyson
$377
American Airlines
Sep 12
TYS6:15 amKnoxville McGhee Tyson
3h 30m
1 stop
CAE9:45 amColumbia Metropolitan
Sep 19
CAE5:25 pmColumbia Metropolitan
5h 25m
1 stop
TYS10:50 pmKnoxville McGhee Tyson
$387
American Airlines
Aug 29
TYS8:12 amKnoxville McGhee Tyson
5h 12m
1 stop
CAE1:24 pmColumbia Metropolitan
Sep 5
CAE4:10 pmColumbia Metropolitan
3h 35m
1 stop
TYS7:45 pmKnoxville McGhee Tyson
$427

United Airlines flights from Knoxville to Columbia

Our best United Airlines deals on Knoxville to Columbia flight tickets
United Airlines
Oct 29
TYS5:45 amKnoxville McGhee Tyson
8h 32m
1 stop
CAE2:17 pmColumbia Metropolitan
Nov 2
CAE7:54 pmColumbia Metropolitan
13h 59m
2 stops
TYS9:53 amKnoxville McGhee Tyson
$611
United Airlines
Sep 12
TYS7:20 pmKnoxville McGhee Tyson
14h 27m
1 stop
CAE9:47 amColumbia Metropolitan
Sep 19
CAE10:22 amColumbia Metropolitan
12h 27m
2 stops
TYS10:49 pmKnoxville McGhee Tyson
$634
United Airlines
Aug 28
TYS7:20 pmKnoxville McGhee Tyson
23h 47m
1 stop
CAE7:07 pmColumbia Metropolitan
Sep 1
CAE7:54 pmColumbia Metropolitan
18h 43m
1 stop
TYS2:37 pmKnoxville McGhee Tyson
$642

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Knoxville to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Thu 10/29

10:00 am-2:03 pm

1 stop4h 03m

Columbia Metropolitan

Mon 11/2

7:12 pm-10:48 pm

1 stop3h 36m

$377

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Sat 9/12

6:15 am-9:45 am

1 stop3h 30m

Columbia Metropolitan

Sat 9/19

5:25 pm-10:50 pm

1 stop5h 25m

$387

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Sat 8/29

8:12 am-1:24 pm

1 stop5h 12m

Columbia Metropolitan

Sat 9/5

4:10 pm-7:45 pm

1 stop3h 35m

$427

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Sat 10/24

10:00 am-3:38 pm

1 stop5h 38m

Columbia Metropolitan

Sun 10/25

5:00 am-10:23 am

1 stop5h 23m

$442

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Fri 8/28

5:40 am-11:09 am

1 stop5h 29m

Columbia Metropolitan

Tue 9/1

5:44 pm-11:52 pm

1 stop6h 08m

$457

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Sat 10/24

10:00 am-3:38 pm

1 stop5h 38m

Columbia Metropolitan

Sun 10/25

5:00 am-10:23 am

1 stop5h 23m

$481
Quickest round-trip

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Fri 10/23

7:58 pm-11:56 pm

1 stop3h 58m

Columbia Metropolitan

Sun 10/25

8:30 pm-11:55 pm

1 stop3h 25m

$507

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Thu 10/29

5:45 am-2:17 pm

1 stop8h 32m

Columbia Metropolitan

Mon 11/2

7:54 pm-9:53 am

2 stops13h 59m

$611

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Sat 9/12

7:20 pm-9:47 am

1 stop14h 27m

Columbia Metropolitan

Sat 9/19

10:22 am-10:49 pm

2 stops12h 27m

$634

KnoxvilleColumbia

TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan

TYSCAE

Knoxville McGhee Tyson

Fri 8/28

7:20 pm-7:07 pm

1 stop23h 47m

Columbia Metropolitan

Tue 9/1

7:54 pm-2:37 pm

1 stop18h 43m

$642

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from Knoxville to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Columbia Metropolitan?

Delta and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Columbia Metropolitan

When to book flights from Knoxville to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Columbia (TYS to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Columbia

Best Price Found

$273

Fastest flight time

3h 22m

Direct flights

None
The best one-way flight to Columbia from Knoxville in the past 72 hours is $273. The best round-trip flight deal from Knoxville to Columbia found on momondo in the last 72 hours is $377.
The fastest flight from Knoxville to Columbia takes 3h 22m
There are no direct flights from Knoxville to Columbia. There are no popular flight routes from Knoxville to Columbia.
Search flight deals

Frequently asked questions about flying from Knoxville to Columbia

  • How far is Knoxville McGhee Tyson to Columbia Metropolitan by plane?

    A flight from Knoxville McGhee Tyson to Columbia Metropolitan will travel around 212.0 mi. 3h 22m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The travel and health documents you'll need for your trip to Columbia Metropolitan Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Metropolitan Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Columbia for you.

Can I find flights from Knoxville to Columbia with flexible booking policies on momondo?

Flights from Knoxville to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Columbia?

Once all potential Knoxville to Columbia flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Columbia right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Columbia, momondo offers a useful price alert feature which will track prices for flights to Columbia from Knoxville and alert you when they change.

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