Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Knoxville to Columbia from $268

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Columbia departing on 8/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:45 am - 11:05 am
TYS
-
CAE
5h 20m
1 stop
Delta Logo
5:40 am - 11:01 am
CAE
-
TYS
5h 21m
1 stop
$367Delta
Fri, Oct 9 - Sun, Oct 11
American Airlines Logo
5:00 am - 10:44 am
TYS
-
CAE
5h 44m
1 stop
American Airlines Logo
8:30 pm - 11:51 pm
CAE
-
TYS
3h 21m
1 stop
$447American Airlines
Tue, Jul 14 - Sat, Jul 18
Delta Logo
6:21 pm - 9:13 pm
TYS
-
CAE
2h 52m
1 stop
Delta Logo
3:44 pm - 8:08 pm
CAE
-
TYS
4h 24m
1 stop
$535Delta
Mon, Oct 12 - Tue, Oct 13
United Airlines Logo
5:45 am - 7:01 pm
TYS
-
CAE
13h 16m
1 stop
United Airlines Logo
2:56 pm - 11:56 pm
CAE
-
TYS
9h 00m
1 stop
$615United Airlines
Thu, Nov 19 - Mon, Nov 23
United Airlines Logo
9:45 am - 7:01 pm
TYS
-
CAE
9h 16m
1 stop
United Airlines Logo
7:50 pm - 9:50 am
CAE
-
TYS
14h 00m
2 stops
$641United Airlines
Thu, Nov 19 - Mon, Nov 23
United Airlines Logo
7:00 am - 7:01 pm
TYS
-
CAE
12h 01m
2 stops
United Airlines Logo
2:56 pm - 9:50 am
CAE
-
TYS
18h 54m
2 stops
$667United Airlines
Thu, Nov 19 - Mon, Nov 23
United Airlines Logo
7:00 am - 7:01 pm
TYS
-
CAE
12h 01m
2 stops
United Airlines Logo
2:56 pm - 9:50 am
CAE
-
TYS
18h 54m
2 stops
$687United Airlines
Thu, Nov 19 - Mon, Nov 23
American Airlines Logo
4:07 pm - 10:38 pm
TYS
-
CAE
6h 31m
2 stops
American Airlines Logo
8:30 pm - 11:51 pm
CAE
-
TYS
3h 21m
1 stop
$818American Airlines
Tue, Jul 14 - Sat, Jul 18
American Airlines Logo
4:07 pm - 10:38 pm
TYS
-
CAE
6h 31m
2 stops
American Airlines Logo
5:00 am - 8:31 am
CAE
-
TYS
3h 31m
1 stop
$838American Airlines
Wed, Jul 15 - Sun, Jul 19
United Airlines Logo
5:45 am - 9:56 am
TYS
-
CAE
4h 11m
1 stop
United Airlines Logo
7:45 pm - 11:54 pm
CAE
-
TYS
4h 09m
1 stop
$937United Airlines
Tue, Jul 14 - Sat, Jul 18

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Knoxville to Columbia

Our best American Airlines deals on Knoxville to Columbia flight tickets
American Airlines
Jul 14
TYS5:00 amKnoxville McGhee Tyson
5h 44m
1 stop
CAE10:44 amColumbia Metropolitan
Jul 18
CAE8:30 pmColumbia Metropolitan
3h 21m
1 stop
TYS11:51 pmKnoxville McGhee Tyson
$447
American Airlines
Jul 14
TYS4:07 pmKnoxville McGhee Tyson
6h 31m
2 stops
CAE10:38 pmColumbia Metropolitan
Jul 18
CAE8:30 pmColumbia Metropolitan
3h 21m
1 stop
TYS11:51 pmKnoxville McGhee Tyson
$818
American Airlines
Jul 15
TYS4:07 pmKnoxville McGhee Tyson
6h 31m
2 stops
CAE10:38 pmColumbia Metropolitan
Jul 19
CAE5:00 amColumbia Metropolitan
3h 31m
1 stop
TYS8:31 amKnoxville McGhee Tyson
$838

United Airlines flights from Knoxville to Columbia

Our best United Airlines deals on Knoxville to Columbia flight tickets
United Airlines
Nov 19
TYS5:45 amKnoxville McGhee Tyson
13h 16m
1 stop
CAE7:01 pmColumbia Metropolitan
Nov 23
CAE2:56 pmColumbia Metropolitan
9h 00m
1 stop
TYS11:56 pmKnoxville McGhee Tyson
$615
United Airlines
Nov 19
TYS9:45 amKnoxville McGhee Tyson
9h 16m
1 stop
CAE7:01 pmColumbia Metropolitan
Nov 23
CAE7:50 pmColumbia Metropolitan
14h 00m
2 stops
TYS9:50 amKnoxville McGhee Tyson
$641
United Airlines
Nov 19
TYS7:00 amKnoxville McGhee Tyson
12h 01m
2 stops
CAE7:01 pmColumbia Metropolitan
Nov 23
CAE2:56 pmColumbia Metropolitan
18h 54m
2 stops
TYS9:50 amKnoxville McGhee Tyson
$667

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Knoxville to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Fri 10/9

5:45 am-11:05 am

1 stop5h 20m

Columbia Metropolitan

Sun 10/11

5:40 am-11:01 am

1 stop5h 21m

$367

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Tue 7/14

5:00 am-10:44 am

1 stop5h 44m

Columbia Metropolitan

Sat 7/18

8:30 pm-11:51 pm

1 stop3h 21m

$447
Quickest round-trip

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Mon 10/12

6:21 pm-9:13 pm

1 stop2h 52m

Columbia Metropolitan

Tue 10/13

3:44 pm-8:08 pm

1 stop4h 24m

$535

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 11/19

5:45 am-7:01 pm

1 stop13h 16m

Columbia Metropolitan

Mon 11/23

2:56 pm-11:56 pm

1 stop9h 00m

$615

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 11/19

9:45 am-7:01 pm

1 stop9h 16m

Columbia Metropolitan

Mon 11/23

7:50 pm-9:50 am

2 stops14h 00m

$641

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 11/19

7:00 am-7:01 pm

2 stops12h 01m

Columbia Metropolitan

Mon 11/23

2:56 pm-9:50 am

2 stops18h 54m

$667

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Thu 11/19

7:00 am-7:01 pm

2 stops12h 01m

Columbia Metropolitan

Mon 11/23

2:56 pm-9:50 am

2 stops18h 54m

$687

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Tue 7/14

4:07 pm-10:38 pm

2 stops6h 31m

Columbia Metropolitan

Sat 7/18

8:30 pm-11:51 pm

1 stop3h 21m

$818

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Wed 7/15

4:07 pm-10:38 pm

2 stops6h 31m

Columbia Metropolitan

Sun 7/19

5:00 am-8:31 am

1 stop3h 31m

$838

KnoxvilleColumbia

TYS - CAE

TYSCAE

Knoxville McGhee Tyson

Tue 7/14

5:45 am-9:56 am

1 stop4h 11m

Columbia Metropolitan

Sat 7/18

7:45 pm-11:54 pm

1 stop4h 09m

$937

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

See travel insights to Columbia from

How to get the cheapest flight ticket from Knoxville to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Columbia Metropolitan?

American Airlines is the most popular carrier operating from Knoxville McGhee Tyson to Columbia Metropolitan

When to book flights from Knoxville to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Columbia (TYS to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Columbia

Fastest flight time

4h 11m

Direct flights

None
The fastest flight from Knoxville to Columbia takes 4h 11m
There are no direct flights from Knoxville to Columbia. There are no popular flight routes from Knoxville to Columbia.
Search flight deals

Frequently asked questions about flying from Knoxville to Columbia

  • How far is Knoxville McGhee Tyson to Columbia Metropolitan by plane?

    A flight from Knoxville McGhee Tyson to Columbia Metropolitan will travel around 212.0 mi. 4h 11m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The travel and health documents you'll need for your trip to Columbia Metropolitan Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Metropolitan Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
West Columbia
Lexington
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Columbia for you.

Can I find flights from Knoxville to Columbia with flexible booking policies on momondo?

Flights from Knoxville to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Columbia?

Once all potential Knoxville to Columbia flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Columbia right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Columbia, momondo offers a useful price alert feature which will track prices for flights to Columbia from Knoxville and alert you when they change.

An easier way to manage your Columbia trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 8/2
Sun 8/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States