What is the cheapest airline that flies from Key West to South Carolina?

Breeze Airways, Delta, and American Airlines are the most popular carriers operating from Key West to South Carolina

How many flights depart from Key West to South Carolina on average per week?

As of September 2026, there are 17 flights per week flying from Key West to South Carolina. The most common day of the week flights depart is Mon, with 18% of flights taking off on this day.

When did momondo last update prices for flights from Key West Airport to South Carolina?

Prices for flights from Key West Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Key West Airport to South Carolina?

There is 1 operator available for flights from Key West Airport to South Carolina as of September 2026.

How old do you have to be to fly from Key West Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Key West Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$89 Cheap Flights from Key West to South Carolina in 2026/27

Find the cheapest flights from Key West to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:59 pm - 1:24 pmEYW Key West-CHS Charleston

24h 25m1 stop Tampa

1:21 pm - 9:24 amCHS Charleston-EYW Key West

20h 03m1 stop Tampa

$210Breeze Airways

Fri, Oct 2 - Tue, Oct 6

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

2:13 pm - 10:19 amCHS Charleston-EYW Key West

20h 06m1 stop Orlando

$242Breeze Airways

Wed, Sep 30 - Sun, Oct 4

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

8:58 pm - 8:56 pmCHS Charleston-EYW Key West

23h 58m1 stop Tampa

$276Multiple Airlines

Wed, Nov 18 - Fri, Nov 20

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

12:05 pm - 9:24 amCLT Charlotte Douglas-EYW Key West

21h 19m2 stops Dallas/Fort Worth Tampa

$279Multiple Airlines

Fri, Oct 2 - Tue, Oct 6

10:59 am - 8:38 amEYW Key West-CHS Charleston

21h 39m1 stop Orlando

8:58 pm - 9:24 amCHS Charleston-EYW Key West

12h 26m1 stop Tampa

$281Breeze Airways

Wed, Nov 25 - Fri, Nov 27

12:59 pm - 2:38 pmEYW Key West-CHS Charleston

25h 39m2 stops Tampa New Orleans Louis Armstrong

1:21 pm - 9:24 amCHS Charleston-EYW Key West

20h 03m1 stop Tampa

$286Breeze Airways

Fri, Oct 2 - Tue, Oct 6

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

10:13 pm - 12:19 pmCHS Charleston-EYW Key West

14h 06m2 stops Fort Lauderdale Tampa

$318Breeze Airways

Wed, Sep 30 - Sun, Oct 4

8:36 pm - 8:35 amEYW Key West-CLT Charlotte Douglas

11h 59m1 stop Orlando Sanford Intl

9:32 am - 8:34 amCLT Charlotte Douglas-EYW Key West

23h 02m1 stop Orlando

$326Multiple Airlines

Thu, Oct 1 - Sun, Oct 4

1:43 pm - 7:27 pmEYW Key West-SAV Savannah/Hilton Head

5h 44m1 stop Miami

6:00 am - 9:54 amSAV Savannah/Hilton Head-EYW Key West

3h 54m1 stop Miami

$467American Airlines

Wed, Oct 14 - Sun, Oct 18

1:43 pm - 7:27 pmEYW Key West-SAV Savannah/Hilton Head

5h 44m1 stop Miami

6:00 am - 9:54 amSAV Savannah/Hilton Head-EYW Key West

3h 54m1 stop Miami

$467American Airlines

Wed, Oct 14 - Sun, Oct 18

Cheap last minute flights

Enter your travel dates to find the best prices.

10:59 am - 7:25 amEYW Key West-CHS Charleston

20h 26m1 stop Orlando

8:58 pm - 9:24 amCHS Charleston-EYW Key West

12h 26m1 stop Tampa

$309Breeze Airways

Thu, Sep 24 - Fri, Sep 25

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

7:54 pm - 11:21 amCLT Charlotte Douglas-EYW Key West

39h 27m2 stops Denver Intl Tampa

$398Multiple Airlines

Thu, Sep 24 - Fri, Sep 25

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

12:05 pm - 9:24 amCLT Charlotte Douglas-EYW Key West

21h 19m2 stops Dallas/Fort Worth Tampa

$421Multiple Airlines

Mon, Sep 21 - Tue, Sep 22

10:59 am - 7:25 amEYW Key West-CHS Charleston

20h 26m1 stop Orlando

9:38 pm - 11:21 amCHS Charleston-EYW Key West

37h 43m2 stops Hartford Bradley Intl Tampa

$471Breeze Airways

Thu, Sep 24 - Fri, Sep 25

2:15 pm - 9:15 pmEYW Key West-CLT Charlotte Douglas

7h 00m1 stop Newark

7:00 am - 1:29 pmCLT Charlotte Douglas-EYW Key West

6h 29m1 stop Newark

$700United Airlines

Thu, Sep 24 - Mon, Sep 28

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

9:40 pm - 11:21 amCLT Charlotte Douglas-EYW Key West

37h 41m3 stops Orlando Akron/Canton Tampa

$735Multiple Airlines

Thu, Sep 24 - Fri, Sep 25

10:59 am - 6:21 pmEYW Key West-CLT Charlotte Douglas

7h 22m1 stop Orlando

9:40 pm - 11:21 amCLT Charlotte Douglas-EYW Key West

37h 41m3 stops Orlando Akron/Canton Tampa

$800Multiple Airlines

Mon, Sep 21 - Tue, Sep 22

2:15 pm - 9:15 pmEYW Key West-CLT Charlotte Douglas

7h 00m1 stop Newark

7:50 pm - 1:29 pmCLT Charlotte Douglas-EYW Key West

17h 39m2 stops Washington, D.C. Dulles Intl Newark

$801United Airlines

Thu, Sep 24 - Mon, Sep 28

3:30 pm - 6:00 pmEYW Key West-CLT Charlotte Douglas

2h 30mnonstop

3:36 pm - 5:55 pmCLT Charlotte Douglas-EYW Key West

2h 19mnonstop

$824American Airlines

Mon, Sep 21 - Tue, Sep 22

3:30 pm - 6:00 pmEYW Key West-CLT Charlotte Douglas

2h 30mnonstop

9:06 am - 1:17 pmCLT Charlotte Douglas-EYW Key West

4h 11m1 stop Miami

$834American Airlines

Mon, Sep 21 - Tue, Sep 22

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United Airlines flights from Key West to South Carolina

Our best United Airlines deals on Key West to South Carolina flight tickets

United Airlines

Sep 24

EYW2:15 pmKey West

7h 00m

1 stop

CLT9:15 pmCharlotte Douglas

Sep 28

CLT7:00 amCharlotte Douglas

6h 29m

1 stop

EYW1:29 pmKey West

$700

United Airlines

Oct 29

EYW2:50 pmKey West

33h 09m

2 stops

CLT11:59 pmCharlotte Douglas

Nov 1

CLT8:10 amCharlotte Douglas

7h 19m

1 stop

EYW3:29 pmKey West

$711

United Airlines

Jan 27

EYW3:04 pmKey West

23h 42m

2 stops

SAV2:46 pmSavannah/Hilton Head

Jan 30

SAV1:50 pmSavannah/Hilton Head

24h 18m

2 stops

EYW2:08 pmKey West

$749

American Airlines flights from Key West to South Carolina

Our best American Airlines deals on Key West to South Carolina flight tickets

American Airlines

Oct 14

EYW1:43 pmKey West

5h 44m

1 stop

SAV7:27 pmSavannah/Hilton Head

Oct 18

SAV6:00 amSavannah/Hilton Head

3h 54m

1 stop

EYW9:54 amKey West

$467

American Airlines

Oct 3

EYW7:47 pmKey West

3h 56m

1 stop

CHS11:43 pmCharleston

Oct 6

CHS8:10 amCharleston

8h 48m

2 stops

EYW4:58 pmKey West

$494

American Airlines

Oct 3

EYW10:21 amKey West

8h 35m

2 stops

CHS6:56 pmCharleston

Oct 6

CHS8:10 amCharleston

8h 48m

2 stops

EYW4:58 pmKey West

$548

momondo Fare Finder

Use the filters below to find and compare flights from Key West to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestCharleston

EYW Key West - CHS Charleston

EYWCHS

Key West

Fri 10/2

12:59 pm-1:24 pm

1 stop24h 25m

Charleston

Tue 10/6

1:21 pm-9:24 am

1 stop20h 03m

$210

Key WestCharleston

EYW Key West - CHS Charleston

EYWCHS

Key West

Wed 9/30

10:04 am-1:24 pm

1 stop3h 20m

Charleston

Sun 10/4

2:13 pm-10:19 am

1 stop20h 06m

$242

Key WestCharleston

EYW Key West - CHS Charleston

EYWCHS

Key West

Wed 11/18

10:04 am-1:24 pm

1 stop3h 20m

Charleston

Fri 11/20

8:58 pm-8:56 pm

1 stop23h 58m

$276

Key WestCharlotte

EYW Key West - CLT Charlotte Douglas

EYWCLT

Key West

Fri 10/2

10:59 am-8:35 am

1 stop21h 36m

Charlotte Douglas

Tue 10/6

12:05 pm-9:24 am

2 stops21h 19m

$279

Key WestCharleston

EYW Key West - CHS Charleston

EYWCHS

Key West

Wed 11/25

10:59 am-8:38 am

1 stop21h 39m

Charleston

Fri 11/27

8:58 pm-9:24 am

1 stop12h 26m

$281

Key WestCharleston

EYW Key West - CHS Charleston

EYWCHS

Key West

Fri 10/2

12:59 pm-2:38 pm

2 stops25h 39m

Charleston

Tue 10/6

1:21 pm-9:24 am

1 stop20h 03m

$286

Key WestCharleston

EYW Key West - CHS Charleston

EYWCHS

Key West

Wed 9/30

10:04 am-1:24 pm

1 stop3h 20m

Charleston

Sun 10/4

10:13 pm-12:19 pm

2 stops14h 06m

$318

Key WestCharlotte

EYW Key West - CLT Charlotte Douglas

EYWCLT

Key West

Thu 10/1

8:36 pm-8:35 am

1 stop11h 59m

Charlotte Douglas

Sun 10/4

9:32 am-8:34 am

1 stop23h 02m

$326

Quickest round-trip

Key WestSavannah

EYW Key West - SAV Savannah/Hilton Head

EYWSAV

Key West

Wed 10/14

1:43 pm-7:27 pm

1 stop5h 44m

Savannah/Hilton Head

Sun 10/18

6:00 am-9:54 am

1 stop3h 54m

$467

Key WestSavannah

EYW Key West - SAV Savannah/Hilton Head

EYWSAV

Key West

Wed 10/14

1:43 pm-7:27 pm

1 stop5h 44m

Savannah/Hilton Head

Sun 10/18

6:00 am-9:54 am

1 stop3h 54m

$467

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Key West to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

Can stopping save me money on Key West to South Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a Key West to South Carolina flight.

Cheap Key West to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to South Carolina

Best Price Found	$89
Fastest flight time	3h 54m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Key West in the past 72 hours is $89. The best round-trip flight deal from Key West to South Carolina found on momondo in the last 72 hours is $210.

The fastest flight from Key West to South Carolina takes 3h 54m

Direct flights go from Key West to South Carolina every day.

There are 57 airports in South Carolina. From Key West there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Key West to South Carolina

When did momondo last update prices for flights from Key West Airport to South Carolina?
Prices for flights from Key West Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Key West Airport to South Carolina?
There is 1 operator available for flights from Key West Airport to South Carolina as of September 2026.
How old do you have to be to fly from Key West Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Key West Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Key West to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Key West.

Can I find flights from Key West to South Carolina with flexible booking policies on momondo?

momondo does allow users to show only those flights to South Carolina from Key West which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Key West to South Carolina?

momondo helps you find the best flight between Key West and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Key West to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.