What is the cheapest airline that flies from Key West to South Carolina?

Breeze Airways, Delta, and American Airlines are the most popular carriers operating from Key West to South Carolina

How many flights depart from Key West to South Carolina on average per week?

As of March 2026, there are 23 flights per week flying from Key West to South Carolina. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

When did momondo last update prices for flights from Key West Airport to South Carolina?

Prices for flights from Key West Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Key West Airport to South Carolina?

There is 1 operator available for flights from Key West Airport to South Carolina as of March 2026.

How old do you have to be to fly from Key West Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Key West Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$73 Cheap Flights from Key West to South Carolina in 2026

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Find the cheapest flights from Key West to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:49 am - 9:53 pm

EYW

CHS

12h 04m

1 stop

3:01 pm - 11:11 am

CHS

EYW

20h 10m

1 stop

$181Breeze Airways

Fri, Apr 3 - Tue, Apr 7

11:51 am - 8:38 am

EYW

CHS

20h 47m

1 stop

3:01 pm - 11:11 am

CHS

EYW

20h 10m

1 stop

$183Breeze Airways

Wed, Apr 8 - Tue, Apr 14

11:51 am - 8:38 am

EYW

CHS

20h 47m

1 stop

8:59 pm - 9:09 am

CHS

EYW

12h 10m

1 stop

$195Breeze Airways

Wed, Apr 8 - Sun, Apr 12

12:25 pm - 12:38 am

EYW

CLT

12h 13m

1 stop

4:33 pm - 12:26 pm

CLT

EYW

19h 53m

1 stop

$225Multiple Airlines

Wed, Apr 8 - Sun, Apr 12

9:46 am - 4:46 pm

EYW

CLT

7h 00m

1 stop

9:00 pm - 12:21 pm

CLT

EYW

15h 21m

2 stops

$232Multiple Airlines

Thu, Apr 2 - Mon, Apr 6

12:25 pm - 11:53 pm

EYW

CLT

35h 28m

3 stops

6:00 am - 11:30 am

CLT

EYW

5h 30m

1 stop

$345Spirit Airlines

Wed, Apr 8 - Sun, Apr 12

12:25 pm - 7:48 pm

EYW

CLT

31h 23m

3 stops

9:00 pm - 11:30 am

CLT

EYW

14h 30m

1 stop

$386Spirit Airlines

Thu, Apr 2 - Mon, Apr 6

7:00 am - 11:00 am

EYW

AGS

4h 00m

1 stop

11:35 am - 5:14 pm

AGS

EYW

5h 39m

1 stop

$407Delta

Wed, Jul 8 - Wed, Jul 15

12:18 pm - 6:22 am

EYW

CLT

18h 04m

1 stop

10:00 am - 12:16 pm

CLT

EYW

2h 16mnonstop

$410American Airlines

Fri, May 29 - Sat, May 30

4:20 pm - 9:45 pm

EYW

SAV

5h 25m

1 stop

5:00 am - 11:16 am

SAV

EYW

6h 16m

1 stop

$427American Airlines

Thu, Apr 30 - Sun, May 3

United Airlines flights from Key West to South Carolina

Our best United Airlines deals on Key West to South Carolina flight tickets

United Airlines

Apr 4

EYW6:22 pmKey West

5h 35m

1 stop

CLT11:57 pmCharlotte Douglas

Apr 8

CLT11:09 amCharlotte Douglas

6h 30m

1 stop

EYW5:39 pmKey West

$661

United Airlines

May 18

EYW4:47 pmKey West

24h 24m

2 stops

CLT5:11 pmCharlotte Douglas

Jun 1

CLT8:05 amCharlotte Douglas

7h 02m

1 stop

EYW3:07 pmKey West

$751

United Airlines

May 7

EYW4:05 pmKey West

8h 40m

1 stop

CLT12:45 amCharlotte Douglas

May 11

CLT8:05 amCharlotte Douglas

7h 02m

1 stop

EYW3:07 pmKey West

$757

American Airlines flights from Key West to South Carolina

Our best American Airlines deals on Key West to South Carolina flight tickets

American Airlines

Apr 22

EYW2:01 pmKey West

5h 42m

1 stop

AGS7:43 pmAugusta Bush Field

Apr 29

AGS4:15 pmAugusta Bush Field

6h 21m

1 stop

EYW10:36 pmKey West

$293

American Airlines

Apr 22

EYW11:24 amKey West

8h 19m

2 stops

AGS7:43 pmAugusta Bush Field

Apr 29

AGS4:15 pmAugusta Bush Field

6h 21m

1 stop

EYW10:36 pmKey West

$361

American Airlines

May 29

EYW12:18 pmKey West

18h 04m

1 stop

CLT6:22 amCharlotte Douglas

May 30

CLT10:00 amCharlotte Douglas

2h 16m

EYW12:16 pmKey West

$410

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 4/3

9:49 am-9:53 pm

1 stop12h 04m

Charleston

Tue 4/7

3:01 pm-11:11 am

1 stop20h 10m

$181

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Wed 4/8

11:51 am-8:38 am

1 stop20h 47m

Charleston

Tue 4/14

3:01 pm-11:11 am

1 stop20h 10m

$183

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Wed 4/8

11:51 am-8:38 am

1 stop20h 47m

Charleston

Sun 4/12

8:59 pm-9:09 am

1 stop12h 10m

$195

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Wed 4/8

12:25 pm-12:38 am

1 stop12h 13m

Charlotte Douglas

Sun 4/12

4:33 pm-12:26 pm

1 stop19h 53m

$225

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Thu 4/2

9:46 am-4:46 pm

1 stop7h 00m

Charlotte Douglas

Mon 4/6

9:00 pm-12:21 pm

2 stops15h 21m

$232

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Wed 4/8

12:25 pm-11:53 pm

3 stops35h 28m

Charlotte Douglas

Sun 4/12

6:00 am-11:30 am

1 stop5h 30m

$345

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Thu 4/2

12:25 pm-7:48 pm

3 stops31h 23m

Charlotte Douglas

Mon 4/6

9:00 pm-11:30 am

1 stop14h 30m

$386

Quickest round-trip

Key WestAugusta

EYW - AGS

EYWAGS

Key West

Wed 7/8

7:00 am-11:00 am

1 stop4h 00m

Augusta Bush Field

Wed 7/15

11:35 am-5:14 pm

1 stop5h 39m

$407

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Fri 5/29

12:18 pm-6:22 am

1 stop18h 04m

Charlotte Douglas

Sat 5/30

10:00 am-12:16 pm

Nonstop2h 16m

$410

Key WestSavannah

EYW - SAV

EYWSAV

Key West

Thu 4/30

4:20 pm-9:45 pm

1 stop5h 25m

Savannah/Hilton Head

Sun 5/3

5:00 am-11:16 am

1 stop6h 16m

$427

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Key West to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

Can stopping save me money on Key West to South Carolina flights?

You could potentially save up to 72% on your flight if you consider stops on a Key West to South Carolina flight.

Cheap Key West to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to South Carolina

Fastest flight time	2h 22m
Direct flights	Mon, Tue, Thu, Fri, Sat and Sun
Airports in South Carolina	57 airports

The fastest flight from Key West to South Carolina takes 2h 22m

Direct flights go from Key West to South Carolina on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Key West there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Key West Airport to South Carolina?
Prices for flights from Key West Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Key West Airport to South Carolina?
There is 1 operator available for flights from Key West Airport to South Carolina as of March 2026.
How old do you have to be to fly from Key West Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Key West Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Key West to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Key West.

Can I find flights from Key West to South Carolina with flexible booking policies on momondo?

momondo does allow users to show only those flights to South Carolina from Key West which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Key West to South Carolina?

momondo helps you find the best flight between Key West and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Key West to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.