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Cheap flights from Key West to Panama City from $239

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Panama City departing on 11/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Delta Logo
6:10 pm - 11:03 pmEYW-ECP
5h 53m1 stop
Delta Logo
7:00 am - 1:02 pmECP-EYW
5h 02m1 stop
$327Delta
Find Deal
sáb., sep. 13 - mar., sep. 16
Delta Logo
6:10 pm - 11:03 pmEYW-ECP
5h 53m1 stop
Delta Logo
6:00 am - 1:02 pmECP-EYW
6h 02m1 stop
$333Delta
Find Deal
sáb., sep. 13 - mar., sep. 16
Delta Logo
6:10 pm - 2:39 pmEYW-ECP
21h 29m2 stops
Delta Logo
6:00 am - 1:02 pmECP-EYW
6h 02m1 stop
$381Delta
Find Deal
sáb., sep. 13 - mar., sep. 16
Delta Logo
6:10 pm - 2:39 pmEYW-ECP
21h 29m2 stops
Delta Logo
7:00 am - 1:02 pmECP-EYW
5h 02m1 stop
$382Delta
Find Deal
sáb., sep. 13 - mar., sep. 16
Delta Logo
6:10 pm - 2:39 pmEYW-ECP
21h 29m2 stops
Delta Logo
6:00 am - 10:55 amECP-EYW
3h 55m1 stop
$396Delta
Find Deal
sáb., sep. 13 - mar., sep. 16
Delta Logo
2:00 pm - 7:30 pmEYW-ECP
6h 30m1 stop
Delta Logo
6:00 am - 10:55 amECP-EYW
3h 55m1 stop
$423Delta
Find Deal
jue., sep. 11 - dom., sep. 14
American Airlines Logo
12:50 pm - 6:29 pmEYW-ECP
6h 39m1 stop
American Airlines Logo
10:13 am - 6:59 pmECP-EYW
7h 46m2 stops
$778American Airlines
Find Deal
jue., sep. 11 - dom., sep. 14
American Airlines Logo
11:25 am - 6:29 pmEYW-ECP
8h 04m2 stops
American Airlines Logo
10:13 am - 6:59 pmECP-EYW
7h 46m2 stops
$927American Airlines
Find Deal
jue., sep. 11 - dom., sep. 14
American Airlines Logo
11:25 am - 9:12 pmEYW-ECP
10h 47m2 stops
American Airlines Logo
6:32 am - 6:59 pmECP-EYW
11h 27m2 stops
$1,138American Airlines
Find Deal
sáb., sep. 13 - mar., sep. 16
American Airlines Logo
12:00 pm - 9:12 pmEYW-ECP
10h 12m2 stops
American Airlines Logo
6:32 am - 6:59 pmECP-EYW
11h 27m2 stops
$1,217American Airlines
Find Deal
sáb., sep. 13 - mar., sep. 16

Delta flights from Key West to Panama City, Florida

Our best Delta deals on Key West to Panama City, Florida flight tickets
Delta
Sep 13
EYW6:10 pmKey West
5h 53m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Sep 16
ECP7:00 amPanama City NW Florida Beaches
5h 02m
1 stop
EYW1:02 pmKey West
$327
Find similar
Delta
Sep 13
EYW6:10 pmKey West
5h 53m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Sep 16
ECP6:00 amPanama City NW Florida Beaches
6h 02m
1 stop
EYW1:02 pmKey West
$333
Find similar
Delta
Sep 13
EYW6:10 pmKey West
21h 29m
2 stops
ECP2:39 pmPanama City NW Florida Beaches
Sep 16
ECP6:00 amPanama City NW Florida Beaches
6h 02m
1 stop
EYW1:02 pmKey West
$381
Find similar

American Airlines flights from Key West to Panama City, Florida

Our best American Airlines deals on Key West to Panama City, Florida flight tickets
American Airlines
Sep 11
EYW12:50 pmKey West
6h 39m
1 stop
ECP6:29 pmPanama City NW Florida Beaches
Sep 14
ECP10:13 amPanama City NW Florida Beaches
7h 46m
2 stops
EYW6:59 pmKey West
$778
Find similar
American Airlines
Sep 11
EYW11:25 amKey West
8h 04m
2 stops
ECP6:29 pmPanama City NW Florida Beaches
Sep 14
ECP10:13 amPanama City NW Florida Beaches
7h 46m
2 stops
EYW6:59 pmKey West
$927
Find similar
American Airlines
Sep 13
EYW11:25 amKey West
10h 47m
2 stops
ECP9:12 pmPanama City NW Florida Beaches
Sep 16
ECP6:32 amPanama City NW Florida Beaches
11h 27m
2 stops
EYW6:59 pmKey West
$1,138
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 25, 2025.
Use the filters below to find and compare flights from Key West to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

6:10 pm-11:03 pm

1 stop5h 53m

Panama City NW Florida Beaches

mar. 9/16

7:00 am-1:02 pm

1 stop5h 02m

$327

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

6:10 pm-11:03 pm

1 stop5h 53m

Panama City NW Florida Beaches

mar. 9/16

6:00 am-1:02 pm

1 stop6h 02m

$333

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

6:10 pm-2:39 pm

2 stops21h 29m

Panama City NW Florida Beaches

mar. 9/16

6:00 am-1:02 pm

1 stop6h 02m

$381

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

6:10 pm-2:39 pm

2 stops21h 29m

Panama City NW Florida Beaches

mar. 9/16

7:00 am-1:02 pm

1 stop5h 02m

$382

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

6:10 pm-2:39 pm

2 stops21h 29m

Panama City NW Florida Beaches

mar. 9/16

6:00 am-10:55 am

1 stop3h 55m

$396

Key WestPanama City

EYW - ECP

EYWECP

Key West

jue. 9/11

2:00 pm-7:30 pm

1 stop6h 30m

Panama City NW Florida Beaches

dom. 9/14

6:00 am-10:55 am

1 stop3h 55m

$423

Key WestPanama City

EYW - ECP

EYWECP

Key West

jue. 9/11

12:50 pm-6:29 pm

1 stop6h 39m

Panama City NW Florida Beaches

dom. 9/14

10:13 am-6:59 pm

2 stops7h 46m

$778

Key WestPanama City

EYW - ECP

EYWECP

Key West

jue. 9/11

11:25 am-6:29 pm

2 stops8h 04m

Panama City NW Florida Beaches

dom. 9/14

10:13 am-6:59 pm

2 stops7h 46m

$927

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

11:25 am-9:12 pm

2 stops10h 47m

Panama City NW Florida Beaches

mar. 9/16

6:32 am-6:59 pm

2 stops11h 27m

$1,138

Key WestPanama City

EYW - ECP

EYWECP

Key West

sáb. 9/13

12:00 pm-9:12 pm

2 stops10h 12m

Panama City NW Florida Beaches

mar. 9/16

6:32 am-6:59 pm

2 stops11h 27m

$1,217

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Key West to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Key West to Panama City NW Florida Beaches?

Delta and American Airlines are the most popular carriers operating from Key West to Panama City NW Florida Beaches

When to book flights from Key West to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Panama City, Florida (EYW to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Panama City, Florida

Direct flights

None
There are no direct flights from Key West to Panama City, Florida. There are no popular flight routes from Key West to Panama City, Florida.
Search flight deals

  • How far is Key West to Panama City NW Florida Beaches by plane?

    Panama City NW Florida Beaches is 453.5 mi away from Key West. Typically, this will take 5h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Key West Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Key West Airport to Panama City NW Florida Beaches Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Key West Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Key West to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Key West to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Key West to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Key West with this policy.

How can momondo help me find flights from Key West to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Key West. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Key West to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Key West are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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