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Cheap flights from Key West to Panama City from $377

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Panama City departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Key West to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:40 am - 12:48 pm
EYW
-
ECP
6h 08m
1 stop
Delta Logo
6:00 am - 10:50 am
ECP
-
EYW
3h 50m
1 stop
$377Delta
Fri, Aug 28 - Sun, Aug 30
American Airlines Logo
4:50 pm - 10:40 pm
EYW
-
ECP
6h 50m
1 stop
American Airlines Logo
6:57 pm - 10:56 am
ECP
-
EYW
14h 59m
2 stops
$624American Airlines
Fri, Aug 28 - Sun, Aug 30
Delta Logo
7:40 am - 10:42 am
EYW
-
ECP
4h 02m
1 stop
Delta Logo
6:00 am - 10:50 am
ECP
-
EYW
3h 50m
1 stop
$645Delta
Mon, Aug 10 - Thu, Aug 13
American Airlines Logo
10:15 am - 10:40 pm
EYW
-
ECP
13h 25m
2 stops
American Airlines Logo
6:57 pm - 1:05 pm
ECP
-
EYW
17h 08m
2 stops
$795American Airlines
Fri, Aug 28 - Sun, Aug 30
United Airlines Logo
4:05 pm - 9:37 am
EYW
-
ECP
18h 32m
1 stop
United Airlines Logo
10:25 am - 1:02 pm
ECP
-
EYW
25h 37m
2 stops
$796United Airlines
Wed, Jan 6 - Sat, Jan 9
United Airlines Logo
6:20 pm - 9:37 am
EYW
-
ECP
16h 17m
2 stops
United Airlines Logo
10:25 am - 1:02 pm
ECP
-
EYW
25h 37m
2 stops
$801United Airlines
Wed, Jan 6 - Sat, Jan 9
United Airlines Logo
4:05 pm - 12:37 pm
EYW
-
ECP
21h 32m
2 stops
United Airlines Logo
10:25 am - 1:02 pm
ECP
-
EYW
25h 37m
2 stops
$801United Airlines
Wed, Jan 6 - Sat, Jan 9
United Airlines Logo
4:05 pm - 9:37 am
EYW
-
ECP
18h 32m
1 stop
United Airlines Logo
10:25 am - 3:06 pm
ECP
-
EYW
27h 41m
1 stop
$823United Airlines
Wed, Jan 6 - Sat, Jan 9
American Airlines Logo
4:50 pm - 10:40 pm
EYW
-
ECP
6h 50m
1 stop
American Airlines Logo
6:40 am - 7:39 pm
ECP
-
EYW
11h 59m
2 stops
$855American Airlines
Mon, Aug 10 - Thu, Aug 13
American Airlines Logo
1:41 pm - 10:40 pm
EYW
-
ECP
9h 59m
2 stops
American Airlines Logo
6:40 am - 7:39 pm
ECP
-
EYW
11h 59m
2 stops
$860American Airlines
Mon, Aug 10 - Thu, Aug 13

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Delta flights from Key West to Panama City, Florida

Our best Delta deals on Key West to Panama City, Florida flight tickets
Delta
Aug 28
EYW7:40 amKey West
6h 08m
1 stop
ECP12:48 pmPanama City NW Florida Beaches
Aug 30
ECP6:00 amPanama City NW Florida Beaches
3h 50m
1 stop
EYW10:50 amKey West
$377
Delta
Aug 10
EYW7:40 amKey West
4h 02m
1 stop
ECP10:42 amPanama City NW Florida Beaches
Aug 13
ECP6:00 amPanama City NW Florida Beaches
3h 50m
1 stop
EYW10:50 amKey West
$645

American Airlines flights from Key West to Panama City, Florida

Our best American Airlines deals on Key West to Panama City, Florida flight tickets
American Airlines
Aug 28
EYW4:50 pmKey West
6h 50m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 30
ECP6:57 pmPanama City NW Florida Beaches
14h 59m
2 stops
EYW10:56 amKey West
$624
American Airlines
Aug 28
EYW10:15 amKey West
13h 25m
2 stops
ECP10:40 pmPanama City NW Florida Beaches
Aug 30
ECP6:57 pmPanama City NW Florida Beaches
17h 08m
2 stops
EYW1:05 pmKey West
$795
American Airlines
Aug 10
EYW4:50 pmKey West
6h 50m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 13
ECP6:40 amPanama City NW Florida Beaches
11h 59m
2 stops
EYW7:39 pmKey West
$855

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Key West to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 8/28

7:40 am-12:48 pm

1 stop6h 08m

Panama City NW Florida Beaches

Sun 8/30

6:00 am-10:50 am

1 stop3h 50m

$377

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 8/28

4:50 pm-10:40 pm

1 stop6h 50m

Panama City NW Florida Beaches

Sun 8/30

6:57 pm-10:56 am

2 stops14h 59m

$624
Quickest round-trip

Key WestPanama City

EYW - ECP

EYWECP

Key West

Mon 8/10

7:40 am-10:42 am

1 stop4h 02m

Panama City NW Florida Beaches

Thu 8/13

6:00 am-10:50 am

1 stop3h 50m

$645

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 8/28

10:15 am-10:40 pm

2 stops13h 25m

Panama City NW Florida Beaches

Sun 8/30

6:57 pm-1:05 pm

2 stops17h 08m

$795

Key WestPanama City

EYW - ECP

EYWECP

Key West

Wed 1/6

4:05 pm-9:37 am

1 stop18h 32m

Panama City NW Florida Beaches

Sat 1/9

10:25 am-1:02 pm

2 stops25h 37m

$796

Key WestPanama City

EYW - ECP

EYWECP

Key West

Wed 1/6

6:20 pm-9:37 am

2 stops16h 17m

Panama City NW Florida Beaches

Sat 1/9

10:25 am-1:02 pm

2 stops25h 37m

$801

Key WestPanama City

EYW - ECP

EYWECP

Key West

Wed 1/6

4:05 pm-12:37 pm

2 stops21h 32m

Panama City NW Florida Beaches

Sat 1/9

10:25 am-1:02 pm

2 stops25h 37m

$801

Key WestPanama City

EYW - ECP

EYWECP

Key West

Wed 1/6

4:05 pm-9:37 am

1 stop18h 32m

Panama City NW Florida Beaches

Sat 1/9

10:25 am-3:06 pm

1 stop27h 41m

$823

Key WestPanama City

EYW - ECP

EYWECP

Key West

Mon 8/10

4:50 pm-10:40 pm

1 stop6h 50m

Panama City NW Florida Beaches

Thu 8/13

6:40 am-7:39 pm

2 stops11h 59m

$855

Key WestPanama City

EYW - ECP

EYWECP

Key West

Mon 8/10

1:41 pm-10:40 pm

2 stops9h 59m

Panama City NW Florida Beaches

Thu 8/13

6:40 am-7:39 pm

2 stops11h 59m

$860

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Key West to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Panama City, Florida (EYW to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Panama City, Florida

Fastest flight time

4h 02m

Direct flights

None
The fastest flight from Key West to Panama City, Florida takes 4h 02m
There are no direct flights from Key West to Panama City, Florida. There are no popular flight routes from Key West to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Key West to Panama City, Florida

  • How far is Key West to Panama City NW Florida Beaches by plane?

    Panama City NW Florida Beaches is 453.5 mi away from Key West. Typically, this will take 4h 02m by plane in normal conditions.

  • When did momondo last update prices for flights from Key West Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Key West Airport to Panama City NW Florida Beaches Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Key West Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Frequently asked questions about flying from Key West to Panama City, Florida

  • How do I get Price Alerts for flights from Key West to Panama City, Florida?

    Price Alerts will notify you by email when the price for flights to Panama City, Florida from Key West decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.

  • How can I save money on flights from Key West to Panama City, Florida with momondo?

    Leverage our AI within our “Price Forecast” tool, which predicts if it’s better to book now or wait until prices decrease. You can strategically pick the best days to fly and save money on your trip by using our “Price Calendar” tool. “Explore” shows an overview of how much it costs to fly to anywhere from a selected city or airport. Our “Discover” content is a great option for travel inspiration and money-saving tips, while “Price Alerts” will update you when prices change, so you can book when fares are right.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Key West to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Key West to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Key West to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Key West with this policy.

How can momondo help me find flights from Key West to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Key West. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Key West to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Key West are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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