What is the cheapest airline that flies from Jacksonville to Des Moines?

Delta, Southwest, and American Airlines are the most popular carriers operating from Jacksonville to Des Moines

Which layover airport offers the lowest fares from Jacksonville to Des Moines?

Flights via Chicago (MDW) offer the lowest average round-trip price of $406.

Which layover airport has the shortest connection time from Jacksonville to Des Moines?

Chicago (ORD) has the shortest average layover time for this route: 1h 08m.

What airlines fly to Des Moines?

Allegiant Air, United Airlines and American Airlines are the top three most popular airlines that fly to Des Moines from Jacksonville according to our data. Allegiant Air is the first choice among our users, with 26% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Jacksonville and Des Moines?

Chicago (ORD) was the most common stop: 82% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Jacksonville to Des Moines?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 5h 00m.

When did momondo last update prices for flights from Jacksonville Airport to Des Moines Airport?

Prices for flights from Jacksonville Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Jacksonville Airport to Des Moines Airport?

As of October 2026, there are 4 operators available to choose from for flights from Jacksonville Airport to Des Moines Airport.

How old do you have to be to fly from Jacksonville Airport to Des Moines Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$137 Cheap Flights from Jacksonville to Des Moines in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Jacksonville to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:55 pm - 3:25 pmJAX Jacksonville-DSM Des Moines

24h 30m1 stop Fort Lauderdale

3:58 pm - 6:11 pmDSM Des Moines-JAX Jacksonville

25h 13m2 stops Orlando Sanford Intl Atlanta Hartsfield-Jackson

$290Multiple Airlines

Wed, Nov 4 - Mon, Nov 9

7:03 pm - 3:25 pmJAX Jacksonville-DSM Des Moines

21h 22m2 stops Atlanta Hartsfield-Jackson Fort Lauderdale

12:25 pm - 8:45 amDSM Des Moines-JAX Jacksonville

19h 20m1 stop Fort Lauderdale

$294Multiple Airlines

Wed, Nov 4 - Sun, Nov 8

3:55 pm - 3:25 pmJAX Jacksonville-DSM Des Moines

24h 30m1 stop Fort Lauderdale

12:25 pm - 8:45 amDSM Des Moines-JAX Jacksonville

19h 20m1 stop Fort Lauderdale

$301Multiple Airlines

Wed, Nov 4 - Sun, Nov 8

6:14 pm - 11:57 pmJAX Jacksonville-DSM Des Moines

6h 43m1 stop Charlotte Douglas

11:09 am - 6:44 pmDSM Des Moines-JAX Jacksonville

6h 35m1 stop Charlotte Douglas

$339American Airlines

Thu, Nov 5 - Mon, Nov 9

6:00 am - 10:49 amJAX Jacksonville-DSM Des Moines

5h 49m1 stop Atlanta Hartsfield-Jackson

6:43 pm - 11:56 pmDSM Des Moines-JAX Jacksonville

4h 13m1 stop Atlanta Hartsfield-Jackson

$339Delta

Wed, Dec 16 - Mon, Dec 21

5:08 pm - 11:26 pmJAX Jacksonville-DSM Des Moines

7h 18m1 stop Charlotte Douglas

5:23 am - 12:54 pmDSM Des Moines-JAX Jacksonville

6h 31m1 stop Dallas/Fort Worth

$363American Airlines

Tue, Nov 17 - Thu, Nov 19

9:44 am - 2:13 pmJAX Jacksonville-DSM Des Moines

5h 29m1 stop Atlanta Hartsfield-Jackson

6:52 pm - 11:53 pmDSM Des Moines-JAX Jacksonville

4h 01m1 stop Atlanta Hartsfield-Jackson

$388Delta

Tue, Nov 17 - Fri, Nov 20

11:37 am - 7:16 pmJAX Jacksonville-DSM Des Moines

8h 39m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

8:00 am - 2:20 pmDSM Des Moines-JAX Jacksonville

5h 20m1 stop Chicago O'Hare Intl

$393United Airlines

Tue, Nov 17 - Fri, Nov 20

5:55 pm - 12:33 amJAX Jacksonville-DSM Des Moines

7h 38m1 stop Chicago O'Hare Intl

2:05 pm - 11:57 pmDSM Des Moines-JAX Jacksonville

8h 52m2 stops Chicago O'Hare Intl Charlotte Douglas

$393American Airlines

Thu, Dec 10 - Sun, Dec 13

3:44 pm - 10:30 pmJAX Jacksonville-DSM Des Moines

7h 46m1 stop Houston George Bush Intcntl

8:00 am - 2:20 pmDSM Des Moines-JAX Jacksonville

5h 20m1 stop Chicago O'Hare Intl

$474United Airlines

Fri, Oct 30 - Mon, Nov 2

Cheap last minute flights

Enter your travel dates to find the best prices.

3:00 pm - 11:10 pmJAX Jacksonville-DSM Des Moines

9h 10m1 stop Fort Lauderdale

2:42 pm - 10:37 amDSM Des Moines-JAX Jacksonville

18h 55m2 stops Las Vegas Harry Reid Intl Philadelphia

$836Multiple Airlines

Sun, Oct 11 - Wed, Oct 14

9:49 am - 10:43 pmJAX Jacksonville-DSM Des Moines

13h 54m1 stop Philadelphia

6:00 am - 7:21 pmDSM Des Moines-JAX Jacksonville

12h 21m1 stop Philadelphia

$845American Airlines

Sat, Oct 10 - Tue, Oct 13

3:04 pm - 9:01 pmJAX Jacksonville-DSM Des Moines

6h 57m1 stop Denver Intl

3:11 pm - 9:47 pmDSM Des Moines-JAX Jacksonville

5h 36m1 stop Chicago O'Hare Intl

$907United Airlines

Sun, Oct 11 - Wed, Oct 14

5:10 am - 10:42 amJAX Jacksonville-DSM Des Moines

6h 32m1 stop Atlanta Hartsfield-Jackson

6:54 pm - 11:56 pmDSM Des Moines-JAX Jacksonville

4h 02m1 stop Atlanta Hartsfield-Jackson

$907Delta

Fri, Oct 9 - Mon, Oct 12

9:00 am - 3:11 pmJAX Jacksonville-DSM Des Moines

7h 11m1 stop Dallas/Fort Worth

4:12 pm - 10:29 pmDSM Des Moines-JAX Jacksonville

5h 17m1 stop Dallas/Fort Worth

$907American Airlines

Thu, Oct 8 - Mon, Oct 12

12:40 pm - 9:23 pmJAX Jacksonville-DSM Des Moines

9h 43m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

3:11 pm - 9:47 pmDSM Des Moines-JAX Jacksonville

5h 36m1 stop Chicago O'Hare Intl

$912United Airlines

Thu, Oct 8 - Mon, Oct 12

5:05 pm - 10:10 pmJAX Jacksonville-DSM Des Moines

6h 05m1 stop Denver Intl

6:20 am - 6:15 pmDSM Des Moines-JAX Jacksonville

10h 55m2 stops Denver Intl Chicago Midway

$912Southwest

Fri, Oct 9 - Mon, Oct 12

3:00 pm - 11:15 pmJAX Jacksonville-DSM Des Moines

9h 15m2 stops Baltimore/Washington Chicago Midway

4:30 pm - 11:25 pmDSM Des Moines-JAX Jacksonville

5h 55m2 stops Chicago Midway Nashville Intl

$917Southwest

Thu, Oct 8 - Mon, Oct 12

6:05 am - 1:30 pmJAX Jacksonville-DSM Des Moines

8h 25m2 stops Charlotte Douglas Chicago O'Hare Intl

9:26 am - 6:35 pmDSM Des Moines-JAX Jacksonville

8h 09m2 stops Chicago O'Hare Intl Charlotte Douglas

$917American Airlines

Sat, Oct 10 - Tue, Oct 13

6:10 am - 2:25 pmJAX Jacksonville-DSM Des Moines

9h 15m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul

10:22 am - 8:40 pmDSM Des Moines-JAX Jacksonville

9h 18m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

$2,525Delta

Sat, Oct 10 - Tue, Oct 13

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American Airlines flights from Jacksonville to Des Moines

Our best American Airlines deals on Jacksonville to Des Moines flight tickets

American Airlines

Nov 5

JAX6:14 pmJacksonville

6h 43m

1 stop

DSM11:57 pmDes Moines

Nov 9

DSM11:09 amDes Moines

6h 35m

1 stop

JAX6:44 pmJacksonville

$339

American Airlines

Nov 17

JAX5:08 pmJacksonville

7h 18m

1 stop

DSM11:26 pmDes Moines

Nov 19

DSM5:23 amDes Moines

6h 31m

1 stop

JAX12:54 pmJacksonville

$363

American Airlines

Nov 5

JAX6:14 pmJacksonville

6h 43m

1 stop

DSM11:57 pmDes Moines

Nov 9

DSM11:09 amDes Moines

6h 35m

1 stop

JAX6:44 pmJacksonville

$413

Southwest flights from Jacksonville to Des Moines

Our best Southwest deals on Jacksonville to Des Moines flight tickets

Southwest

Nov 17

JAX6:35 amJacksonville

8h 40m

2 stops

DSM2:15 pmDes Moines

Nov 19

DSM3:30 pmDes Moines

5h 40m

1 stop

JAX10:10 pmJacksonville

$369

Southwest

Nov 17

JAX6:05 amJacksonville

9h 10m

2 stops

DSM2:15 pmDes Moines

Nov 19

DSM7:00 amDes Moines

9h 00m

2 stops

JAX5:00 pmJacksonville

$374

Southwest

Feb 2

JAX11:05 amJacksonville

10h 35m

2 stops

DSM8:40 pmDes Moines

Feb 5

DSM5:20 amDes Moines

11h 30m

2 stops

JAX5:50 pmJacksonville

$423

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 11/4

3:55 pm-3:25 pm

1 stop24h 30m

Des Moines

Mon 11/9

3:58 pm-6:11 pm

2 stops25h 13m

$290

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 11/4

7:03 pm-3:25 pm

2 stops21h 22m

Des Moines

Sun 11/8

12:25 pm-8:45 am

1 stop19h 20m

$294

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 11/4

3:55 pm-3:25 pm

1 stop24h 30m

Des Moines

Sun 11/8

12:25 pm-8:45 am

1 stop19h 20m

$301

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Thu 11/5

6:14 pm-11:57 pm

1 stop6h 43m

Des Moines

Mon 11/9

11:09 am-6:44 pm

1 stop6h 35m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 12/16

6:00 am-10:49 am

1 stop5h 49m

Des Moines

Mon 12/21

6:43 pm-11:56 pm

1 stop4h 13m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Tue 11/17

5:08 pm-11:26 pm

1 stop7h 18m

Des Moines

Thu 11/19

5:23 am-12:54 pm

1 stop6h 31m

$363

Quickest round-trip

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Tue 11/17

9:44 am-2:13 pm

1 stop5h 29m

Des Moines

Fri 11/20

6:52 pm-11:53 pm

1 stop4h 01m

$388

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Tue 11/17

11:37 am-7:16 pm

2 stops8h 39m

Des Moines

Fri 11/20

8:00 am-2:20 pm

1 stop5h 20m

$393

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Thu 12/10

5:55 pm-12:33 am

1 stop7h 38m

Des Moines

Sun 12/13

2:05 pm-11:57 pm

2 stops8h 52m

$393

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Fri 10/30

3:44 pm-10:30 pm

1 stop7h 46m

Des Moines

Mon 11/2

8:00 am-2:20 pm

1 stop5h 20m

$474

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Jacksonville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Jacksonville and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $387 to $422.
The lowest price recently found on this route was $290.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then November is your next best option. Flight prices from Jacksonville to Des Moines during November average around $113.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Jacksonville to Des Moines in the evening for as low as $110. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $113. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Jacksonville to Des Moines flight route?

Fly from Jacksonville to Des Moines for the best Jacksonville - Des Moines flight prices

What cabin class options are available on Jacksonville to Des Moines flights?

There is only 1 cabin class available to choose from on Jacksonville to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Jacksonville to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Jacksonville to Des Moines.

How have Jacksonville to Des Moines flight prices changed over time?

As of October 2026, prices for Jacksonville to Des Moines flights are approximately 73% cheaper when compared to flights at the same time last year.

When to book flights from Jacksonville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Jacksonville to Des Moines (JAX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Des Moines

Best Price Found	$137
Fastest flight time	4h 24m
Direct flights	None

The best one-way flight to Des Moines from Jacksonville in the past 72 hours is $137. The best round-trip flight deal from Jacksonville to Des Moines found on momondo in the last 72 hours is $290.

The fastest flight from Jacksonville to Des Moines takes 4h 24m

There are no direct flights from Jacksonville to Des Moines. There are no popular flight routes from Jacksonville to Des Moines.

Search flight deals

Frequently asked questions about flying from Jacksonville to Des Moines

How far is Jacksonville to Des Moines by plane?
Des Moines is 1023.3 mi away from Jacksonville. A reasonable flight in good conditions will take 4h 24m.
When did momondo last update prices for flights from Jacksonville Airport to Des Moines Airport?
Prices for flights from Jacksonville Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Jacksonville Airport to Des Moines Airport?
As of October 2026, there are 4 operators available to choose from for flights from Jacksonville Airport to Des Moines Airport.
How old do you have to be to fly from Jacksonville Airport to Des Moines Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Jacksonville to Des Moines?
momondo data reveals that the most frequently booked plane model on the route from Jacksonville to Des Moines is Airbus A320-100/200, representing 29.41% of all bookings. The subsequent popular models are Embraer 175 at 11.76%, Boeing 737 MAX 8 at 5.88%, and Airbus A319 at 5.88%.
What is the most popular airline from Jacksonville to Des Moines?
Based on momondo bookings for flights between Jacksonville and Des Moines, the leading airline is Allegiant Air, making up 26% of the total bookings. Other popular airlines include United Airlines with 25%, American Airlines with 24%, and Delta with 24%.

Best airlines flying from Jacksonville to Des Moines

Compare and see reviews for airlines that fly from Jacksonville to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $40	Free Cancellation	Rating 7.3 678 reviews	Search Allegiant Air flights
Delta	PriceFrom $202	Free Cancellation	Rating 7.8 8,628 reviews	Search Delta flights
American Airlines	PriceFrom $286	Free Cancellation	Rating 7.0 12,126 reviews	Search American Airlines flights
United Airlines	PriceFrom $296	Free Cancellation	Rating 7.4 10,283 reviews	Search United Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Osceola

Urbandale

Newton

Boone

Johnston

Oskaloosa

Grinnell

Norwalk

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Jacksonville to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Jacksonville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Des Moines?

Once all potential Jacksonville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Jacksonville to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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Cheap flights from Jacksonville to Des Moines from $137

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Des Moines departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Jacksonville to Des Moines

Our best American Airlines deals on Jacksonville to Des Moines flight tickets

Southwest flights from Jacksonville to Des Moines

Our best Southwest deals on Jacksonville to Des Moines flight tickets

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How to get the cheapest flight ticket from Jacksonville to Des Moines

What is the typical price of a round-trip flight between Jacksonville and Des Moines?

What is the cheapest month to fly to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Jacksonville to Des Moines flight route?

What cabin class options are available on Jacksonville to Des Moines flights?

Can stopping save me money on Jacksonville to Des Moines flights?

How have Jacksonville to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Jacksonville to Des Moines?

What airlines fly to Des Moines?

Which airport is the most popular layover for flights between Jacksonville and Des Moines?

Which layover airport offers the lowest fares from Jacksonville to Des Moines?

Which layover airport has the shortest travel time from Jacksonville to Des Moines?

Which layover airport has the shortest connection time from Jacksonville to Des Moines?

When to book flights from Jacksonville to Des Moines

Cheap Jacksonville to Des Moines (JAX to DSM) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Jacksonville to Des Moines

Best airlines flying from Jacksonville to Des Moines

Compare and see reviews for airlines that fly from Jacksonville to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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