Which layover airport has the shortest travel time from Jacksonville to Des Moines?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 5h 00m.

Which airport is the most popular layover for flights between Jacksonville and Des Moines?

Chicago (ORD) was the most common stop: 82% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Jacksonville to Des Moines?

Flights via Chicago (MDW) offer the lowest average round-trip price of $406.

What is the cheapest airline that flies from Jacksonville to Des Moines?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Jacksonville to Des Moines

Which layover airport has the shortest connection time from Jacksonville to Des Moines?

Chicago (ORD) has the shortest average layover time for this route: 1h 08m.

What airlines fly to Des Moines?

United Airlines, Allegiant Air and American Airlines are the top three most popular airlines that fly to Des Moines from Jacksonville according to our data. United Airlines is the first choice among our users, with 31% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Jacksonville Airport to Des Moines Airport?

Prices for flights from Jacksonville Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Jacksonville Airport to Des Moines Airport?

As of August 2026, there are 4 operators available to choose from for flights from Jacksonville Airport to Des Moines Airport.

How old do you have to be to fly from Jacksonville Airport to Des Moines Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$170 Cheap Flights from Jacksonville to Des Moines in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Jacksonville to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:50 pm - 4:52 pmJAX Jacksonville-DSM Des Moines

26h 02m1 stop Fort Lauderdale

2:49 pm - 4:26 pmDSM Des Moines-JAX Jacksonville

24h 37m2 stops Fort Myers SW Florida Intl Raleigh-Durham

$322Multiple Airlines

Wed, Oct 7 - Mon, Oct 12

9:15 am - 7:57 pmJAX Jacksonville-DSM Des Moines

11h 42m1 stop Philadelphia

1:58 pm - 7:01 pmDSM Des Moines-JAX Jacksonville

28h 03m2 stops Philadelphia Atlanta Hartsfield-Jackson

$326Multiple Airlines

Thu, Sep 10 - Sun, Sep 13

7:46 pm - 7:57 pmJAX Jacksonville-DSM Des Moines

25h 11m2 stops Atlanta Hartsfield-Jackson Philadelphia

1:58 pm - 8:20 amDSM Des Moines-JAX Jacksonville

17h 22m1 stop Philadelphia

$329Multiple Airlines

Wed, Sep 9 - Thu, Sep 17

7:30 am - 12:16 pmJAX Jacksonville-DSM Des Moines

5h 46m1 stop Chicago O'Hare Intl

3:22 pm - 11:20 pmDSM Des Moines-JAX Jacksonville

6h 58m1 stop Chicago O'Hare Intl

$339United Airlines

Tue, Sep 15 - Tue, Sep 22

4:45 pm - 9:28 pmJAX Jacksonville-DSM Des Moines

5h 43m1 stop Chicago O'Hare Intl

6:24 am - 2:05 pmDSM Des Moines-JAX Jacksonville

6h 41m1 stop Chicago O'Hare Intl

$339United Airlines

Tue, Sep 15 - Thu, Sep 17

1:45 pm - 6:54 pmJAX Jacksonville-DSM Des Moines

6h 09m1 stop Dallas/Fort Worth

7:02 am - 12:24 pmDSM Des Moines-JAX Jacksonville

4h 22m1 stop Charlotte Douglas

$339American Airlines

Wed, Dec 16 - Mon, Dec 21

6:18 pm - 12:04 amJAX Jacksonville-DSM Des Moines

6h 46m1 stop Chicago O'Hare Intl

2:29 pm - 10:40 pmDSM Des Moines-JAX Jacksonville

7h 11m1 stop Chicago O'Hare Intl

$339American Airlines

Wed, Sep 9 - Wed, Sep 16

6:00 am - 10:46 amJAX Jacksonville-DSM Des Moines

5h 46m1 stop Atlanta Hartsfield-Jackson

6:54 pm - 11:58 pmDSM Des Moines-JAX Jacksonville

4h 04m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sat, Sep 12 - Mon, Sep 14

4:10 pm - 10:37 pmJAX Jacksonville-DSM Des Moines

7h 27m1 stop Atlanta Hartsfield-Jackson

6:54 pm - 11:58 pmDSM Des Moines-JAX Jacksonville

4h 04m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sun, Sep 6 - Thu, Sep 17

6:14 pm - 12:35 amJAX Jacksonville-DSM Des Moines

7h 21m1 stop Chicago O'Hare Intl

6:41 am - 1:00 pmDSM Des Moines-JAX Jacksonville

5h 19m1 stop Dallas/Fort Worth

$339American Airlines

Sat, Sep 5 - Sat, Sep 12

Cheap last minute flights

Enter your travel dates to find the best prices.

9:45 am - 10:06 pmJAX Jacksonville-DSM Des Moines

13h 21m1 stop Philadelphia

2:29 pm - 10:40 pmDSM Des Moines-JAX Jacksonville

7h 11m1 stop Chicago O'Hare Intl

$609American Airlines

Thu, Aug 27 - Wed, Sep 30

9:45 am - 10:06 pmJAX Jacksonville-DSM Des Moines

13h 21m1 stop Philadelphia

1:09 pm - 11:30 pmDSM Des Moines-JAX Jacksonville

9h 21m2 stops Philadelphia Charlotte Douglas

$629American Airlines

Thu, Aug 27 - Wed, Sep 30

8:59 pm - 6:48 pmJAX Jacksonville-DSM Des Moines

22h 49m2 stops Philadelphia Las Vegas Harry Reid Intl

1:55 pm - 10:03 amDSM Des Moines-JAX Jacksonville

19h 08m1 stop Philadelphia

$664Multiple Airlines

Thu, Aug 27 - Sun, Aug 30

11:51 am - 8:26 pmJAX Jacksonville-DSM Des Moines

9h 35m2 stops Washington, D.C. Dulles Intl Denver Intl

5:45 am - 7:09 pmDSM Des Moines-JAX Jacksonville

12h 24m2 stops Denver Intl Chicago O'Hare Intl

$668United Airlines

Thu, Aug 27 - Wed, Sep 30

7:05 pm - 9:00 pmJAX Jacksonville-DSM Des Moines

26h 55m2 stops Atlanta Hartsfield-Jackson Las Vegas Harry Reid Intl

7:38 pm - 7:45 pmDSM Des Moines-JAX Jacksonville

23h 07m1 stop Las Vegas Harry Reid Intl

$818Multiple Airlines

Wed, Aug 26 - Fri, Aug 28

4:45 pm - 9:23 pmJAX Jacksonville-DSM Des Moines

5h 38m1 stop Chicago O'Hare Intl

8:00 am - 2:04 pmDSM Des Moines-JAX Jacksonville

5h 04m1 stop Chicago O'Hare Intl

$887United Airlines

Thu, Aug 27 - Sun, Aug 30

11:03 am - 4:27 pmJAX Jacksonville-DSM Des Moines

6h 24m1 stop Charlotte Douglas

5:10 pm - 11:06 pmDSM Des Moines-JAX Jacksonville

4h 56m1 stop Charlotte Douglas

$887American Airlines

Wed, Aug 26 - Fri, Aug 28

12:37 pm - 5:28 pmJAX Jacksonville-DSM Des Moines

5h 51m1 stop Chicago O'Hare Intl

8:00 am - 8:54 pmDSM Des Moines-JAX Jacksonville

11h 54m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$892United Airlines

Wed, Aug 26 - Fri, Aug 28

2:00 pm - 10:10 pmJAX Jacksonville-DSM Des Moines

9h 10m2 stops Lambert-St Louis Chicago Midway

5:40 am - 3:40 pmDSM Des Moines-JAX Jacksonville

9h 00m2 stops Chicago Midway Nashville Intl

$897Southwest

Thu, Aug 27 - Sun, Aug 30

6:15 am - 1:55 pmJAX Jacksonville-DSM Des Moines

8h 40m2 stops Lambert-St Louis Denver Intl

5:40 am - 3:15 pmDSM Des Moines-JAX Jacksonville

8h 35m2 stops Chicago Midway Baltimore/Washington

$897Southwest

Wed, Aug 26 - Fri, Aug 28

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United Airlines flights from Jacksonville to Des Moines

Our best United Airlines deals on Jacksonville to Des Moines flight tickets

United Airlines

Sep 5

JAX7:30 amJacksonville

5h 48m

1 stop

DSM12:18 pmDes Moines

Sep 9

DSM6:24 amDes Moines

10h 38m

2 stops

JAX6:02 pmJacksonville

$344

United Airlines

Sep 11

JAX3:07 pmJacksonville

9h 26m

1 stop

DSM11:33 pmDes Moines

Sep 14

DSM3:22 pmDes Moines

6h 58m

1 stop

JAX11:20 pmJacksonville

$429

United Airlines

Sep 2

JAX4:45 pmJacksonville

5h 38m

1 stop

DSM9:23 pmDes Moines

Sep 5

DSM6:00 amDes Moines

8h 19m

2 stops

JAX3:19 pmJacksonville

$433

Southwest flights from Jacksonville to Des Moines

Our best Southwest deals on Jacksonville to Des Moines flight tickets

Southwest

Sep 9

JAX1:40 pmJacksonville

9h 20m

2 stops

DSM10:00 pmDes Moines

Sep 16

DSM6:10 amDes Moines

6h 10m

2 stops

JAX1:20 pmJacksonville

$349

Southwest

Sep 15

JAX1:40 pmJacksonville

9h 20m

2 stops

DSM10:00 pmDes Moines

Sep 17

DSM3:50 pmDes Moines

5h 15m

1 stop

JAX10:05 pmJacksonville

$364

Southwest

Sep 15

JAX1:40 pmJacksonville

9h 20m

2 stops

DSM10:00 pmDes Moines

Sep 17

DSM5:40 amDes Moines

10h 25m

2 stops

JAX5:05 pmJacksonville

$375

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 10/7

3:50 pm-4:52 pm

1 stop26h 02m

Des Moines

Mon 10/12

2:49 pm-4:26 pm

2 stops24h 37m

$322

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Thu 9/10

9:15 am-7:57 pm

1 stop11h 42m

Des Moines

Sun 9/13

1:58 pm-7:01 pm

2 stops28h 03m

$326

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 9/9

7:46 pm-7:57 pm

2 stops25h 11m

Des Moines

Thu 9/17

1:58 pm-8:20 am

1 stop17h 22m

$329

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Tue 9/15

7:30 am-12:16 pm

1 stop5h 46m

Des Moines

Tue 9/22

3:22 pm-11:20 pm

1 stop6h 58m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Tue 9/15

4:45 pm-9:28 pm

1 stop5h 43m

Des Moines

Thu 9/17

6:24 am-2:05 pm

1 stop6h 41m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 12/16

1:45 pm-6:54 pm

1 stop6h 09m

Des Moines

Mon 12/21

7:02 am-12:24 pm

1 stop4h 22m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Wed 9/9

6:18 pm-12:04 am

1 stop6h 46m

Des Moines

Wed 9/16

2:29 pm-10:40 pm

1 stop7h 11m

$339

Quickest round-trip

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Sat 9/12

6:00 am-10:46 am

1 stop5h 46m

Des Moines

Mon 9/14

6:54 pm-11:58 pm

1 stop4h 04m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Sun 9/6

4:10 pm-10:37 pm

1 stop7h 27m

Des Moines

Thu 9/17

6:54 pm-11:58 pm

1 stop4h 04m

$339

JacksonvilleDes Moines

JAX Jacksonville - DSM Des Moines

JAXDSM

Jacksonville

Sat 9/5

6:14 pm-12:35 am

1 stop7h 21m

Des Moines

Sat 9/12

6:41 am-1:00 pm

1 stop5h 19m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Jacksonville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Jacksonville and Des Moines?

Prices are currently typical for flights on this route.

Typical prices usually range from $280 to $492.
The lowest price recently found on this route was $322.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then October is your next best option. Flight prices from Jacksonville to Des Moines during October average around $109.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Jacksonville to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $109. Flights from Jacksonville to Des Moines on a Sunday will generally be more expensive and average around $210. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Jacksonville to Des Moines in the evening for as low as $110. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $111. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Jacksonville to Des Moines flight route?

Fly from Jacksonville to Des Moines for the best Jacksonville - Des Moines flight prices

What cabin class options are available on Jacksonville to Des Moines flights?

There is only 1 cabin class available to choose from on Jacksonville to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Jacksonville to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Jacksonville to Des Moines.

How have Jacksonville to Des Moines flight prices changed over time?

As of August 2026, prices for Jacksonville to Des Moines flights are approximately 72% cheaper when compared to flights at the same time last year.

When to book flights from Jacksonville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Jacksonville to Des Moines (JAX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Des Moines

Best Price Found	$170
Fastest flight time	4h 27m
Direct flights	None

The best one-way flight to Des Moines from Jacksonville in the past 72 hours is $170. The best round-trip flight deal from Jacksonville to Des Moines found on momondo in the last 72 hours is $322.

The fastest flight from Jacksonville to Des Moines takes 4h 27m

There are no direct flights from Jacksonville to Des Moines. There are no popular flight routes from Jacksonville to Des Moines.

Search flight deals

Frequently asked questions about flying from Jacksonville to Des Moines

How far is Jacksonville to Des Moines by plane?
Des Moines is 1023.3 mi away from Jacksonville. A reasonable flight in good conditions will take 4h 27m.
When did momondo last update prices for flights from Jacksonville Airport to Des Moines Airport?
Prices for flights from Jacksonville Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Jacksonville Airport to Des Moines Airport?
As of August 2026, there are 4 operators available to choose from for flights from Jacksonville Airport to Des Moines Airport.
How old do you have to be to fly from Jacksonville Airport to Des Moines Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Jacksonville to Des Moines?
momondo data reveals that the most frequently booked plane model on the route from Jacksonville to Des Moines is Airbus A320-100/200, representing 57.14% of all bookings. The subsequent popular models are Embraer 175 at 7.14%, Boeing 737 MAX 8 at 3.57%, and Airbus A319 at 3.57%.
What is the most popular airline from Jacksonville to Des Moines?
Based on momondo bookings for flights between Jacksonville and Des Moines, the leading airline is United Airlines, making up 31% of the total bookings. Other popular airlines include Allegiant Air with 30%, American Airlines with 19%, and Delta with 19%.

Best airlines flying from Jacksonville to Des Moines

Compare and see reviews for airlines that fly from Jacksonville to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $40	Free Cancellation	Rating 7.3 676 reviews	Search Allegiant Air flights
Delta	PriceFrom $202	Free Cancellation	Rating 7.8 8,519 reviews	Search Delta flights
American Airlines	PriceFrom $286	Free Cancellation	Rating 7.1 11,989 reviews	Search American Airlines flights
United Airlines	PriceFrom $296	Free Cancellation	Rating 7.4 10,110 reviews	Search United Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Urbandale

Newton

Osceola

Johnston

Boone

Oskaloosa

Norwalk

Grinnell

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Jacksonville to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Jacksonville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Des Moines?

Once all potential Jacksonville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Jacksonville to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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Cheap flights from Jacksonville to Des Moines from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Des Moines departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Jacksonville to Des Moines

Our best United Airlines deals on Jacksonville to Des Moines flight tickets

Southwest flights from Jacksonville to Des Moines

Our best Southwest deals on Jacksonville to Des Moines flight tickets

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How to get the cheapest flight ticket from Jacksonville to Des Moines

What is the typical price of a round-trip flight between Jacksonville and Des Moines?

What is the cheapest month to fly to Des Moines?

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Jacksonville to Des Moines flight route?

What cabin class options are available on Jacksonville to Des Moines flights?

Can stopping save me money on Jacksonville to Des Moines flights?

How have Jacksonville to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Jacksonville to Des Moines?

What airlines fly to Des Moines?

Which airport is the most popular layover for flights between Jacksonville and Des Moines?

Which layover airport offers the lowest fares from Jacksonville to Des Moines?

Which layover airport has the shortest travel time from Jacksonville to Des Moines?

Which layover airport has the shortest connection time from Jacksonville to Des Moines?

When to book flights from Jacksonville to Des Moines

Cheap Jacksonville to Des Moines (JAX to DSM) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Jacksonville to Des Moines

Best airlines flying from Jacksonville to Des Moines

Compare and see reviews for airlines that fly from Jacksonville to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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