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Cheap flights from Jacksonville to Des Moines from $198

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Des Moines departing on 3/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Jacksonville to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:30 am - 10:48 am
JAX
-
DSM
6h 18m
1 stop
Delta Logo
5:20 pm - 12:02 am
DSM
-
JAX
5h 42m
1 stop
$383Delta
Fri, Mar 27 - Mon, Mar 30
American Airlines Logo
7:00 am - 1:05 pm
JAX
-
DSM
7h 05m
1 stop
American Airlines Logo
5:00 am - 3:05 pm
DSM
-
JAX
9h 05m
2 stops
$388American Airlines
Fri, Feb 27 - Mon, Mar 2
American Airlines Logo
1:43 pm - 10:20 pm
JAX
-
DSM
9h 37m
2 stops
American Airlines Logo
5:00 am - 12:53 pm
DSM
-
JAX
6h 53m
2 stops
$394American Airlines
Fri, Feb 27 - Mon, Mar 2
Delta Logo
6:30 am - 12:14 pm
JAX
-
DSM
6h 44m
1 stop
Delta Logo
5:15 pm - 12:01 am
DSM
-
JAX
5h 46m
1 stop
$412Delta
Sat, Feb 14 - Tue, Feb 17
United Airlines Logo
6:25 am - 2:17 pm
JAX
-
DSM
8h 52m
1 stop
United Airlines Logo
3:24 pm - 9:24 pm
DSM
-
JAX
5h 00m
1 stop
$416United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
4:16 pm - 11:43 pm
JAX
-
DSM
8h 27m
1 stop
United Airlines Logo
7:52 am - 4:25 pm
DSM
-
JAX
7h 33m
1 stop
$417United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
6:25 am - 2:17 pm
JAX
-
DSM
8h 52m
1 stop
United Airlines Logo
8:00 am - 8:14 pm
DSM
-
JAX
11h 14m
2 stops
$421United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
7:45 am - 2:27 pm
JAX
-
DSM
7h 42m
1 stop
United Airlines Logo
8:00 am - 8:14 pm
DSM
-
JAX
11h 14m
2 stops
$422United Airlines
Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
1:22 pm - 9:39 pm
JAX
-
DSM
9h 17m
2 stops
American Airlines Logo
5:00 am - 3:10 pm
DSM
-
JAX
9h 10m
2 stops
$423American Airlines
Sat, Feb 14 - Tue, Feb 17
United Airlines Logo
9:20 am - 5:47 pm
JAX
-
DSM
9h 27m
2 stops
United Airlines Logo
8:00 am - 10:39 pm
DSM
-
JAX
13h 39m
2 stops
$427United Airlines
Sat, Feb 14 - Wed, Feb 18

American Airlines flights from Jacksonville to Des Moines

Our best American Airlines deals on Jacksonville to Des Moines flight tickets
American Airlines
Feb 27
JAX7:00 amJacksonville
7h 05m
1 stop
DSM1:05 pmDes Moines
Mar 2
DSM5:00 amDes Moines
9h 05m
2 stops
JAX3:05 pmJacksonville
$388
American Airlines
Feb 27
JAX1:43 pmJacksonville
9h 37m
2 stops
DSM10:20 pmDes Moines
Mar 2
DSM5:00 amDes Moines
6h 53m
2 stops
JAX12:53 pmJacksonville
$394
American Airlines
Feb 14
JAX1:22 pmJacksonville
9h 17m
2 stops
DSM9:39 pmDes Moines
Feb 17
DSM5:00 amDes Moines
9h 10m
2 stops
JAX3:10 pmJacksonville
$423

United Airlines flights from Jacksonville to Des Moines

Our best United Airlines deals on Jacksonville to Des Moines flight tickets
United Airlines
Feb 14
JAX6:25 amJacksonville
8h 52m
1 stop
DSM2:17 pmDes Moines
Feb 18
DSM3:24 pmDes Moines
5h 00m
1 stop
JAX9:24 pmJacksonville
$416
United Airlines
Feb 14
JAX4:16 pmJacksonville
8h 27m
1 stop
DSM11:43 pmDes Moines
Feb 18
DSM7:52 amDes Moines
7h 33m
1 stop
JAX4:25 pmJacksonville
$417
United Airlines
Feb 14
JAX6:25 amJacksonville
8h 52m
1 stop
DSM2:17 pmDes Moines
Feb 18
DSM8:00 amDes Moines
11h 14m
2 stops
JAX8:14 pmJacksonville
$421

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Jacksonville to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 3/27

5:30 am-10:48 am

1 stop6h 18m

Des Moines

Mon 3/30

5:20 pm-12:02 am

1 stop5h 42m

$383

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 2/27

7:00 am-1:05 pm

1 stop7h 05m

Des Moines

Mon 3/2

5:00 am-3:05 pm

2 stops9h 05m

$388

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 2/27

1:43 pm-10:20 pm

2 stops9h 37m

Des Moines

Mon 3/2

5:00 am-12:53 pm

2 stops6h 53m

$394

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

6:30 am-12:14 pm

1 stop6h 44m

Des Moines

Tue 2/17

5:15 pm-12:01 am

1 stop5h 46m

$412

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

6:25 am-2:17 pm

1 stop8h 52m

Des Moines

Wed 2/18

3:24 pm-9:24 pm

1 stop5h 00m

$416

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

4:16 pm-11:43 pm

1 stop8h 27m

Des Moines

Wed 2/18

7:52 am-4:25 pm

1 stop7h 33m

$417

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

6:25 am-2:17 pm

1 stop8h 52m

Des Moines

Wed 2/18

8:00 am-8:14 pm

2 stops11h 14m

$421

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

7:45 am-2:27 pm

1 stop7h 42m

Des Moines

Wed 2/18

8:00 am-8:14 pm

2 stops11h 14m

$422

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

1:22 pm-9:39 pm

2 stops9h 17m

Des Moines

Tue 2/17

5:00 am-3:10 pm

2 stops9h 10m

$423

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Sat 2/14

9:20 am-5:47 pm

2 stops9h 27m

Des Moines

Wed 2/18

8:00 am-10:39 pm

2 stops13h 39m

$427

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Jacksonville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Jacksonville and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then October is your next best option. Flight prices from Jacksonville to Des Moines during October average around $109.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Jacksonville to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $94. Flights from Jacksonville to Des Moines on a Sunday will generally be more expensive and average around $100. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest Jacksonville to Des Moines flight route?

Fly from Jacksonville to Des Moines for the best Jacksonville - Des Moines flight prices

What cabin class options are available on Jacksonville to Des Moines flights?

There is only 1 cabin class available to choose from on Jacksonville to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Jacksonville to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Jacksonville to Des Moines.

How have Jacksonville to Des Moines flight prices changed over time?

As of January 2026, prices for Jacksonville to Des Moines flights are approximately 91% more expensive when compared to flights at the same time last year.

When to book flights from Jacksonville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Des Moines (JAX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Des Moines

Fastest flight time

2h 37m

Direct flights

None
The fastest flight from Jacksonville to Des Moines takes 2h 37m
There are no direct flights from Jacksonville to Des Moines. There are no popular flight routes from Jacksonville to Des Moines.
Search flight deals

  • How far is Jacksonville to Des Moines by plane?

    Des Moines is 1023.3 mi away from Jacksonville. A reasonable flight in good conditions will take 2h 37m.

  • When did momondo last update prices for flights from Jacksonville Airport to Des Moines Airport?

    Prices for flights from Jacksonville Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Jacksonville Airport to Des Moines Airport?

  • How old do you have to be to fly from Jacksonville Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Jacksonville to Des Moines?

  • What is the most popular airline from Jacksonville to Des Moines?

Best airlines flying from Jacksonville to Des Moines

Compare and see reviews for airlines that fly from Jacksonville to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $81Free CancellationRating
7.2
706 reviews
Search Allegiant Air flights
DeltaPriceFrom $130Free CancellationRating
7.9
8,113 reviews
Search Delta flights
United AirlinesPriceFrom $232Free CancellationRating
7.4
9,199 reviews
Search United Airlines flights
SouthwestPriceFrom $280Free CancellationRating
8.0
4,268 reviews
Search Southwest flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,189 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Jacksonville to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Jacksonville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Des Moines?

Once all potential Jacksonville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Jacksonville to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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