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Cheap flights from Jacksonville to Des Moines from $284

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Des Moines departing on 12/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Jacksonville to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:05 pm - 10:30 pm
JAX
-
DSM
6h 25m1 stop
United Airlines Logo
3:04 pm - 9:47 pm
DSM
-
JAX
5h 43m1 stop
$347United Airlines
mié., ene. 14 - jue., ene. 15
United Airlines Logo
10:40 am - 9:50 pm
JAX
-
DSM
12h 10m2 stops
United Airlines Logo
3:04 pm - 9:47 pm
DSM
-
JAX
5h 43m1 stop
$352United Airlines
mié., ene. 14 - jue., ene. 15
Southwest Logo
11:50 am - 9:10 pm
JAX
-
DSM
10h 20m2 stops
Southwest Logo
5:20 am - 5:25 pm
DSM
-
JAX
11h 05m2 stops
$357Southwest
mié., ene. 14 - jue., ene. 15
American Airlines Logo
9:33 am - 1:21 pm
JAX
-
DSM
4h 48m1 stop
American Airlines Logo
8:45 am - 5:57 pm
DSM
-
JAX
8h 12m1 stop
$389American Airlines
vie., dic. 26 - jue., ene. 1
American Airlines Logo
6:00 am - 12:54 pm
JAX
-
DSM
7h 54m2 stops
American Airlines Logo
8:45 am - 5:57 pm
DSM
-
JAX
8h 12m1 stop
$394American Airlines
vie., dic. 26 - jue., ene. 1
United Airlines Logo
7:40 am - 2:33 pm
JAX
-
DSM
7h 53m1 stop
United Airlines Logo
3:14 pm - 9:42 pm
DSM
-
JAX
5h 28m1 stop
$399United Airlines
vie., dic. 26 - mié., dic. 31
American Airlines Logo
6:05 pm - 12:37 am
JAX
-
DSM
7h 32m1 stop
American Airlines Logo
6:40 am - 1:06 pm
DSM
-
JAX
5h 26m1 stop
$400American Airlines
vie., dic. 26 - mié., dic. 31
American Airlines Logo
6:00 am - 12:54 pm
JAX
-
DSM
7h 54m2 stops
American Airlines Logo
6:40 am - 1:06 pm
DSM
-
JAX
5h 26m1 stop
$405American Airlines
vie., dic. 26 - mié., dic. 31
Southwest Logo
5:05 am - 1:15 pm
JAX
-
DSM
9h 10m1 stop
Southwest Logo
4:20 pm - 10:05 pm
DSM
-
JAX
4h 45m1 stop
$407Southwest
jue., may. 14 - lun., may. 18
Southwest Logo
6:55 am - 6:35 pm
JAX
-
DSM
12h 40m2 stops
Southwest Logo
4:20 pm - 10:05 pm
DSM
-
JAX
4h 45m1 stop
$412Southwest
jue., may. 14 - lun., may. 18

United Airlines flights from Jacksonville to Des Moines

Our best United Airlines deals on Jacksonville to Des Moines flight tickets
United Airlines
Jan 14
JAX5:05 pmJacksonville
6h 25m
1 stop
DSM10:30 pmDes Moines
Jan 15
DSM3:04 pmDes Moines
5h 43m
1 stop
JAX9:47 pmJacksonville
$347
Find similar
United Airlines
Jan 14
JAX10:40 amJacksonville
12h 10m
2 stops
DSM9:50 pmDes Moines
Jan 15
DSM3:04 pmDes Moines
5h 43m
1 stop
JAX9:47 pmJacksonville
$352
Find similar
United Airlines
Dec 26
JAX7:40 amJacksonville
7h 53m
1 stop
DSM2:33 pmDes Moines
Dec 31
DSM3:14 pmDes Moines
5h 28m
1 stop
JAX9:42 pmJacksonville
$399
Find similar

Southwest flights from Jacksonville to Des Moines

Our best Southwest deals on Jacksonville to Des Moines flight tickets
Southwest
Jan 14
JAX11:50 amJacksonville
10h 20m
2 stops
DSM9:10 pmDes Moines
Jan 15
DSM5:20 amDes Moines
11h 05m
2 stops
JAX5:25 pmJacksonville
$357
Find similar
Southwest
May 14
JAX5:05 amJacksonville
9h 10m
1 stop
DSM1:15 pmDes Moines
May 18
DSM4:20 pmDes Moines
4h 45m
1 stop
JAX10:05 pmJacksonville
$407
Find similar
Southwest
May 14
JAX6:55 amJacksonville
12h 40m
2 stops
DSM6:35 pmDes Moines
May 18
DSM4:20 pmDes Moines
4h 45m
1 stop
JAX10:05 pmJacksonville
$412
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 10, 2025.
Use the filters below to find and compare flights from Jacksonville to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

mié. 1/14

5:05 pm-10:30 pm

1 stop6h 25m

Des Moines

jue. 1/15

3:04 pm-9:47 pm

1 stop5h 43m

$347

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

mié. 1/14

10:40 am-9:50 pm

2 stops12h 10m

Des Moines

jue. 1/15

3:04 pm-9:47 pm

1 stop5h 43m

$352

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

mié. 1/14

11:50 am-9:10 pm

2 stops10h 20m

Des Moines

jue. 1/15

5:20 am-5:25 pm

2 stops11h 05m

$357

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

vie. 12/26

9:33 am-1:21 pm

1 stop4h 48m

Des Moines

jue. 1/1

8:45 am-5:57 pm

1 stop8h 12m

$389

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

vie. 12/26

6:00 am-12:54 pm

2 stops7h 54m

Des Moines

jue. 1/1

8:45 am-5:57 pm

1 stop8h 12m

$394

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

vie. 12/26

7:40 am-2:33 pm

1 stop7h 53m

Des Moines

mié. 12/31

3:14 pm-9:42 pm

1 stop5h 28m

$399

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

vie. 12/26

6:05 pm-12:37 am

1 stop7h 32m

Des Moines

mié. 12/31

6:40 am-1:06 pm

1 stop5h 26m

$400

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

vie. 12/26

6:00 am-12:54 pm

2 stops7h 54m

Des Moines

mié. 12/31

6:40 am-1:06 pm

1 stop5h 26m

$405

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

jue. 5/14

5:05 am-1:15 pm

1 stop9h 10m

Des Moines

lun. 5/18

4:20 pm-10:05 pm

1 stop4h 45m

$407

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

jue. 5/14

6:55 am-6:35 pm

2 stops12h 40m

Des Moines

lun. 5/18

4:20 pm-10:05 pm

1 stop4h 45m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Jacksonville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then October is your next best option. Flight prices from Jacksonville to Des Moines during October average around $109.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Jacksonville to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $94. Flights from Jacksonville to Des Moines on a Saturday will generally be more expensive and average around $462. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Jacksonville to Des Moines in the morning for as low as $97. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $558. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Jacksonville to Des Moines flight route?

Fly from Jacksonville to Des Moines for the best Jacksonville - Des Moines flight prices

What cabin class options are available on Jacksonville to Des Moines flights?

There is only 1 cabin class available to choose from on Jacksonville to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Jacksonville to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Jacksonville to Des Moines.

How have Jacksonville to Des Moines flight prices changed over time?

As of December 2025, prices for Jacksonville to Des Moines flights are approximately 95% more expensive when compared to flights at the same time last year.

When to book flights from Jacksonville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Des Moines (JAX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Des Moines

Fastest flight time

2h 37m

Direct flights

None
The fastest flight from Jacksonville to Des Moines takes 2h 37m
There are no direct flights from Jacksonville to Des Moines. There are no popular flight routes from Jacksonville to Des Moines.
Search flight deals

  • How far is Jacksonville to Des Moines by plane?

    Des Moines is 1023.3 mi away from Jacksonville. A reasonable flight in good conditions will take 2h 37m.

  • When did momondo last update prices for flights from Jacksonville Airport to Des Moines Airport?

    Prices for flights from Jacksonville Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Jacksonville Airport to Des Moines Airport?

  • How old do you have to be to fly from Jacksonville Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Jacksonville to Des Moines?

  • What is the most popular airline from Jacksonville to Des Moines?

Best airlines flying from Jacksonville to Des Moines

Compare and see reviews for airlines that fly from Jacksonville to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $82Free CancellationRating
7.2
699 reviews
Search Allegiant Air flights
DeltaPriceFrom $158Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $232Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
SouthwestPriceFrom $280Free CancellationRating
7.9
4,252 reviews
Search Southwest flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Jacksonville to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Jacksonville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Des Moines?

Once all potential Jacksonville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Jacksonville to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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