How many flights depart from Indiana to Knoxville on average per week?

As of September 2026, there are 149 flights per week flying from Indiana to Knoxville. The most common day of the week flights depart is Sun, with 19% of flights taking off on this day.

What is the cheapest airline that flies from Indiana to Knoxville McGhee Tyson?

Allegiant Air, Southwest, and American Airlines are the most popular carriers operating from Indiana to Knoxville McGhee Tyson

What airlines fly to Knoxville?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Knoxville from Indiana according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Knoxville?

Average flight duration from Indiana to Knoxville depends on which airport you fly into and out of. Flying from South Bend to Knoxville is 3h 55m on average, while flying from Indianapolis to Knoxville is 4h 47m on average. Knoxville is the most popular airport in Knoxville.

When did momondo last update prices for flights from Indiana to Knoxville McGhee Tyson Airport?

Prices for flights from Indiana to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from Indiana to Knoxville McGhee Tyson Airport?

As of September 2026, there are 5 operators available to choose from for flights from Indiana to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Indiana to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indiana to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$52 Cheap Flights from Indiana to Knoxville in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Indiana to Knoxville

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:16 pm - 5:46 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 30mnonstop

2:09 pm - 12:18 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

23h 09m1 stop Valparaiso Destin-Ft Walton Beach

$232Allegiant Air

Fri, Nov 13 - Sun, Nov 15

10:42 am - 5:02 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

29h 20m1 stop Punta Gorda

8:00 am - 8:39 amTYS Knoxville McGhee Tyson-MDW Chicago Midway

1h 39mnonstop

$233Allegiant Air

Sun, Nov 15 - Mon, Nov 23

3:16 pm - 5:46 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 30mnonstop

3:42 pm - 7:02 amTYS Knoxville McGhee Tyson-MDW Chicago Midway

16h 20m2 stops Washington, D.C. Dulles Intl Atlanta Hartsfield-Jackson

$234Multiple Airlines

Fri, Nov 13 - Thu, Nov 19

4:31 pm - 7:01 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 30mnonstop

6:17 pm - 11:47 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

30h 30m2 stops Fort Lauderdale Atlanta Hartsfield-Jackson

$235Multiple Airlines

Mon, Nov 16 - Wed, Nov 18

6:30 pm - 10:45 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

3h 15m1 stop Nashville Intl

7:25 pm - 11:55 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

5h 30m1 stop Nashville Intl

$259Southwest

Mon, Oct 19 - Mon, Oct 26

7:40 am - 3:40 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

7h 00m1 stop Denver Intl

12:25 pm - 4:45 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

5h 20m1 stop Dallas Love Field

$259Southwest

Wed, Oct 28 - Sat, Oct 31

1:25 pm - 4:12 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 47mnonstop

11:35 am - 12:37 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 02mnonstop

$273American Airlines

Mon, Oct 19 - Mon, Oct 26

7:58 pm - 11:55 pmIND Indianapolis-TYS Knoxville McGhee Tyson

3h 57m1 stop Charlotte Douglas

12:41 pm - 6:06 pmTYS Knoxville McGhee Tyson-IND Indianapolis

5h 25m1 stop Charlotte Douglas

$273American Airlines

Sat, Oct 17 - Tue, Oct 20

7:00 am - 10:54 amIND Indianapolis-TYS Knoxville McGhee Tyson

3h 54m1 stop Atlanta Hartsfield-Jackson

8:35 am - 1:10 pmTYS Knoxville McGhee Tyson-IND Indianapolis

4h 35m1 stop Atlanta Hartsfield-Jackson

$273Delta

Tue, Oct 6 - Sat, Oct 10

5:53 pm - 9:29 pmAZO Kalamazoo Intl-TYS Knoxville McGhee Tyson

3h 36m1 stop Detroit Metropolitan Wayne County

7:06 am - 11:00 amTYS Knoxville McGhee Tyson-AZO Kalamazoo Intl

3h 54m1 stop Detroit Metropolitan Wayne County

$288Delta

Wed, Nov 11 - Sun, Nov 15

Cheap last minute flights

Enter your travel dates to find the best prices.

7:25 am - 6:34 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

10h 09m1 stop Philadelphia

5:40 pm - 3:20 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

22h 40m1 stop Fort Lauderdale

$310Multiple Airlines

Fri, Sep 11 - Mon, Sep 14

7:00 am - 9:54 amORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 54mnonstop

6:00 am - 6:55 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

1h 55mnonstop

$319United Airlines

Wed, Sep 9 - Wed, Sep 16

4:50 pm - 7:43 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 53mnonstop

8:15 pm - 9:30 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 15mnonstop

$329American Airlines

Thu, Sep 10 - Sat, Sep 12

1:24 pm - 4:11 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 47mnonstop

11:20 am - 12:18 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

1h 58mnonstop

$329American Airlines

Thu, Sep 10 - Sat, Sep 12

6:05 am - 10:44 amMDW Chicago Midway-TYS Knoxville McGhee Tyson

3h 39m1 stop Atlanta Hartsfield-Jackson

11:45 am - 4:57 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

6h 12m1 stop Detroit Metropolitan Wayne County

$349Delta

Thu, Sep 10 - Sat, Sep 12

5:30 am - 10:44 amORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

4h 14m1 stop Atlanta Hartsfield-Jackson

11:45 am - 4:14 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

5h 29m1 stop Detroit Metropolitan Wayne County

$349Delta

Thu, Sep 10 - Sat, Sep 12

7:25 am - 1:25 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

5h 00m1 stop Dallas Love Field

6:50 am - 11:20 amTYS Knoxville McGhee Tyson-MDW Chicago Midway

5h 30m1 stop Nashville Intl

$349Southwest

Thu, Sep 10 - Sat, Sep 12

6:00 am - 2:20 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

7h 20m1 stop Dallas Love Field

1:55 pm - 8:50 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

7h 55m1 stop Denver Intl

$349Southwest

Wed, Sep 9 - Sat, Sep 12

8:02 pm - 10:49 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 47mnonstop

6:00 am - 6:55 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

1h 55mnonstop

$349United Airlines

Wed, Sep 9 - Sun, Sep 13

7:11 am - 10:04 amORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

25h 53m1 stop Fort Lauderdale

5:21 pm - 2:45 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

22h 24m1 stop Fort Lauderdale

$358Multiple Airlines

Wed, Sep 9 - Thu, Sep 10

Cheap direct flights

Enter your travel dates to find the best prices.

4:30 pm - 6:55 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 25mnonstop

12:04 pm - 12:36 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

1h 32mnonstop

$235Allegiant Air

Fri, Oct 16 - Mon, Oct 19

12:26 pm - 2:51 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 25mnonstop

12:04 pm - 12:36 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

1h 32mnonstop

$238Allegiant Air

Fri, Oct 9 - Mon, Oct 12

4:30 pm - 6:55 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 25mnonstop

12:04 pm - 12:36 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

1h 32mnonstop

$245Allegiant Air

Fri, Oct 16 - Mon, Oct 19

1:25 pm - 4:12 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 47mnonstop

11:35 am - 12:37 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 02mnonstop

$273American Airlines

Mon, Oct 19 - Mon, Oct 26

8:59 pm - 11:50 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 51mnonstop

8:48 pm - 10:00 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 12mnonstop

$278American Airlines

Wed, Dec 30 - Tue, Jan 5

6:59 am - 9:45 amORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 46mnonstop

6:00 am - 6:56 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

1h 56mnonstop

$279United Airlines

Thu, Oct 15 - Mon, Oct 19

2:20 pm - 5:15 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 55mnonstop

6:40 am - 7:50 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 10mnonstop

$279United Airlines

Thu, Dec 17 - Tue, Jan 5

8:55 pm - 11:47 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 52mnonstop

7:39 am - 9:00 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 21mnonstop

$279American Airlines

Fri, Nov 20 - Sun, Nov 22

3:29 pm - 6:20 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 51mnonstop

6:55 pm - 8:03 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

2h 08mnonstop

$279American Airlines

Sat, Oct 24 - Mon, Oct 26

3:27 pm - 5:54 pmMDW Chicago Midway-TYS Knoxville McGhee Tyson

1h 27mnonstop

1:58 pm - 2:37 pmTYS Knoxville McGhee Tyson-MDW Chicago Midway

1h 39mnonstop

$362Allegiant Air

Wed, Nov 25 - Sun, Nov 29

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

American Airlines flights from Indiana to Knoxville

Our best American Airlines deals on Indiana to Knoxville flight tickets

American Airlines

Oct 19

ORD1:25 pmChicago O'Hare Intl

1h 47m

TYS4:12 pmKnoxville McGhee Tyson

Oct 26

TYS11:35 amKnoxville McGhee Tyson

2h 02m

ORD12:37 pmChicago O'Hare Intl

$273

American Airlines

Dec 30

ORD8:59 pmChicago O'Hare Intl

1h 51m

TYS11:50 pmKnoxville McGhee Tyson

Jan 5

TYS8:48 pmKnoxville McGhee Tyson

2h 12m

ORD10:00 pmChicago O'Hare Intl

$278

American Airlines

Oct 29

ORD8:20 amChicago O'Hare Intl

1h 45m

TYS11:05 amKnoxville McGhee Tyson

Oct 31

TYS11:35 amKnoxville McGhee Tyson

2h 02m

ORD12:37 pmChicago O'Hare Intl

$279

Allegiant Air flights from Indiana to Knoxville

Our best Allegiant Air deals on Indiana to Knoxville flight tickets

Allegiant Air

Nov 13

MDW3:16 pmChicago Midway

1h 30m

TYS5:46 pmKnoxville McGhee Tyson

Nov 15

TYS2:09 pmKnoxville McGhee Tyson

23h 09m

1 stop

MDW12:18 pmChicago Midway

$232

Allegiant Air

Nov 15

MDW10:42 amChicago Midway

29h 20m

1 stop

TYS5:02 pmKnoxville McGhee Tyson

Nov 23

TYS8:00 amKnoxville McGhee Tyson

1h 39m

MDW8:39 amChicago Midway

$233

Allegiant Air

Oct 9

MDW12:26 pmChicago Midway

1h 25m

TYS2:51 pmKnoxville McGhee Tyson

Oct 12

TYS12:04 pmKnoxville McGhee Tyson

1h 32m

MDW12:36 pmChicago Midway

$238

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

MDW Chicago Midway - TYS Knoxville McGhee Tyson

MDWTYS

Chicago Midway

Fri 11/13

3:16 pm-5:46 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Sun 11/15

2:09 pm-12:18 pm

1 stop23h 09m

$232

ChicagoKnoxville

MDW Chicago Midway - TYS Knoxville McGhee Tyson

MDWTYS

Chicago Midway

Sun 11/15

10:42 am-5:02 pm

1 stop29h 20m

Knoxville McGhee Tyson

Mon 11/23

8:00 am-8:39 am

Nonstop1h 39m

$233

ChicagoKnoxville

MDW Chicago Midway - TYS Knoxville McGhee Tyson

MDWTYS

Chicago Midway

Fri 11/13

3:16 pm-5:46 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Thu 11/19

3:42 pm-7:02 am

2 stops16h 20m

$234

ChicagoKnoxville

MDW Chicago Midway - TYS Knoxville McGhee Tyson

MDWTYS

Chicago Midway

Mon 11/16

4:31 pm-7:01 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Wed 11/18

6:17 pm-11:47 pm

2 stops30h 30m

$235

ChicagoKnoxville

MDW Chicago Midway - TYS Knoxville McGhee Tyson

MDWTYS

Chicago Midway

Mon 10/19

6:30 pm-10:45 pm

1 stop3h 15m

Knoxville McGhee Tyson

Mon 10/26

7:25 pm-11:55 pm

1 stop5h 30m

$259

ChicagoKnoxville

MDW Chicago Midway - TYS Knoxville McGhee Tyson

MDWTYS

Chicago Midway

Wed 10/28

7:40 am-3:40 pm

1 stop7h 00m

Knoxville McGhee Tyson

Sat 10/31

12:25 pm-4:45 pm

1 stop5h 20m

$259

Quickest round-trip

ChicagoKnoxville

ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson

ORDTYS

Chicago O'Hare Intl

Mon 10/19

1:25 pm-4:12 pm

Nonstop1h 47m

Knoxville McGhee Tyson

Mon 10/26

11:35 am-12:37 pm

Nonstop2h 02m

$273

IndianapolisKnoxville

IND Indianapolis - TYS Knoxville McGhee Tyson

INDTYS

Indianapolis

Sat 10/17

7:58 pm-11:55 pm

1 stop3h 57m

Knoxville McGhee Tyson

Tue 10/20

12:41 pm-6:06 pm

1 stop5h 25m

$273

IndianapolisKnoxville

IND Indianapolis - TYS Knoxville McGhee Tyson

INDTYS

Indianapolis

Tue 10/6

7:00 am-10:54 am

1 stop3h 54m

Knoxville McGhee Tyson

Sat 10/10

8:35 am-1:10 pm

1 stop4h 35m

$273

KalamazooKnoxville

AZO Kalamazoo Intl - TYS Knoxville McGhee Tyson

AZOTYS

Kalamazoo Intl

Wed 11/11

5:53 pm-9:29 pm

1 stop3h 36m

Knoxville McGhee Tyson

Sun 11/15

7:06 am-11:00 am

1 stop3h 54m

$288

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Indiana, with most prices found around $163. If you aren’t able to travel during the month of November, then book flights to Knoxville from Indiana during December instead. Flights to Knoxville in December, while not as cheap as those in November, still average around $293.

What is the cheapest Indiana to Knoxville McGhee Tyson flight route?

Fly from South Bend/Michiana to Knoxville McGhee Tyson for the best Indiana - Knoxville McGhee Tyson flight prices

What cabin class options are available on Indiana to Knoxville flights?

There is only 1 cabin class available to choose from on Indiana to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Indiana to Knoxville.

Cheap Indiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to Knoxville

Best Price Found	$52
Fastest flight time	1h 25m
Direct flights	Every day
Airports in Knoxville	1 airport

The best one-way flight to Knoxville from Indiana in the past 72 hours is $52. The best round-trip flight deal from Indiana to Knoxville found on momondo in the last 72 hours is $232.

The fastest flight from Indiana to Knoxville takes 1h 25m

Direct flights go from Indiana to Knoxville every day.

There is 1 airport in Knoxville. From Indiana there are direct flights to Knoxville McGhee Tyson (TYS).

Search flight deals

Frequently asked questions about flying from Indiana to Knoxville

When did momondo last update prices for flights from Indiana to Knoxville McGhee Tyson Airport?
Prices for flights from Indiana to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Indiana to Knoxville McGhee Tyson Airport?
As of September 2026, there are 5 operators available to choose from for flights from Indiana to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Indiana to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indiana to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Indiana to Knoxville?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Indiana to Knoxville is Embraer 175 (Enhanced Winglets) (18.18% of total bookings). The next most popular plane models are Embraer 175 (18.18%), Canadair (Bombardier) Regional Jet CRJ-550 (18.18%), and Airbus A320-100/200 (18.18%).

Best airlines flying from Indiana to Knoxville

Compare and see reviews for airlines that fly from Indiana to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $107	Free Cancellation	Rating 7.4 10,175 reviews	Search United Airlines flights
Delta	PriceFrom $208	Free Cancellation	Rating 7.8 8,548 reviews	Search Delta flights
American Airlines	PriceFrom $217	Free Cancellation	Rating 7.1 12,042 reviews	Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Alcoa

Maryville

Crossville

Murphy

Oak Ridge

Kodak

Newport

Dandridge

Clinton

Lenoir City

Rockford

Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Indiana.

Can I find flights from Indiana to Knoxville with flexible booking policies on momondo?

All flight searches from Indiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Indiana to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to Knoxville.

I’m not ready to book a flight from Indiana to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indiana to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Wed 10/7

Wed 10/14

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Indiana

Complete your trip

Feeling lucky

Airports servicing Tennessee

Nashville Intl Airport

Chattanooga Lovell Field Airport

Memphis Airport

Jackson Mckellar Field Airport

Blountville Tri Cities TN/VA Airport

Cheap flights from Indiana to Knoxville from $52

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to Knoxville departing on 11/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Indiana to Knoxville

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

American Airlines flights from Indiana to Knoxville

Our best American Airlines deals on Indiana to Knoxville flight tickets

Allegiant Air flights from Indiana to Knoxville

Our best Allegiant Air deals on Indiana to Knoxville flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indiana to Knoxville that are best for you.

See travel insights to Knoxville from

How to get the cheapest flight ticket from Indiana to Knoxville

What is the cheapest month to fly to Knoxville?

What is the cheapest Indiana to Knoxville McGhee Tyson flight route?

What cabin class options are available on Indiana to Knoxville flights?

Can stopping save me money on Indiana to Knoxville flights?

What is the cheapest airline that flies from Indiana to Knoxville McGhee Tyson?

What airlines fly to Knoxville?

How many flights depart from Indiana to Knoxville on average per week?

How long does it take to fly to Knoxville?

Cheap Indiana to Knoxville flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in Knoxville

Frequently asked questions about flying from Indiana to Knoxville

Best airlines flying from Indiana to Knoxville

Compare and see reviews for airlines that fly from Indiana to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee

Fly your favorite airline to Knoxville

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Knoxville

List of cabin classes available on flights landing in Knoxville. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Indiana

According to popular flight searches on momondo this year

Complete your trip to Knoxville

Explore popular destinations other users love

According to popular flight searches on momondo this year