What is the cheapest airline that flies from Indiana to Knoxville McGhee Tyson?

Southwest, United Airlines, and Delta are the most popular carriers operating from Indiana to Knoxville McGhee Tyson

What airlines fly to Knoxville?

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Indiana according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 4 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

How many flights depart from Indiana to Knoxville on average per week?

As of March 2026, there are 139 flights per week flying from Indiana to Knoxville. The most common day of the week flights depart is Fri, with 19% of flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Indiana to Knoxville depends on which airport you fly into and out of. Flying from Indianapolis to Knoxville is 3h 21m on average, while flying from South Bend to Knoxville is 3h 47m on average. Knoxville is the most popular airport in Knoxville.

When did momondo last update prices for flights from Indiana to Knoxville McGhee Tyson Airport?

Prices for flights from Indiana to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from Indiana to Knoxville McGhee Tyson Airport?

As of March 2026, there are 4 operators available to choose from for flights from Indiana to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Indiana to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indiana to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$54 Cheap Flights from Indiana to Knoxville in 2026

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Find the cheapest flights from Indiana to Knoxville

Round-trip

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Cheap round-trip flights

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8:30 am - 11:18 am

ORD

TYS

1h 48mnonstop

8:48 pm - 9:57 pm

TYS

ORD

2h 09mnonstop

$189American Airlines

ter, abr 7 - seg, abr 13

5:24 pm - 8:18 pm

ORD

TYS

1h 54mnonstop

8:48 pm - 9:57 pm

TYS

ORD

2h 09mnonstop

$190American Airlines

qui, abr 9 - seg, abr 13

7:50 pm - 10:34 pm

ORD

TYS

1h 44mnonstop

7:00 am - 7:55 am

TYS

ORD

1h 55mnonstop

$199United Airlines

sáb, abr 25 - seg, abr 27

7:50 pm - 10:34 pm

ORD

TYS

1h 44mnonstop

7:00 am - 7:55 am

TYS

ORD

1h 55mnonstop

$204United Airlines

sex, abr 3 - seg, abr 6

8:15 am - 3:07 pm

ORD

TYS

5h 52m

1 stop

1:30 pm - 7:02 pm

TYS

ORD

6h 32m

1 stop

$209Delta

dom, ago 16 - sáb, ago 22

12:13 pm - 6:17 pm

SBN

TYS

6h 04m

1 stop

7:30 am - 1:46 pm

TYS

SBN

6h 16m

1 stop

$209Delta

sáb, ago 22 - qua, ago 26

2:40 pm - 7:40 pm

ORD

TYS

4h 00m

1 stop

12:50 pm - 6:25 pm

TYS

ORD

6h 35m

1 stop

$210Southwest

ter, abr 28 - qua, abr 29

1:27 pm - 10:36 am

ORD

TYS

20h 09m

1 stop

11:27 am - 9:40 am

TYS

ORD

47h 13m

2 stops

$211Multiple Airlines

ter, abr 14 - dom, abr 19

2:40 pm - 7:40 pm

ORD

TYS

4h 00m

1 stop

6:35 am - 12:50 pm

TYS

ORD

7h 15m

1 stop

$214Southwest

ter, abr 14 - qui, abr 16

7:41 pm - 11:37 pm

MDW

TYS

26h 56m

1 stop

1:22 pm - 1:57 pm

TYS

MDW

1h 35mnonstop

$217Multiple Airlines

qui, mai 28 - dom, mai 31

American Airlines flights from Indiana to Knoxville

Our best American Airlines deals on Indiana to Knoxville flight tickets

American Airlines

Apr 9

ORD5:24 pmChicago O'Hare Intl

1h 54m

TYS8:18 pmKnoxville McGhee Tyson

Apr 13

TYS8:48 pmKnoxville McGhee Tyson

2h 09m

ORD9:57 pmChicago O'Hare Intl

$190

American Airlines

Mar 17

ORD6:40 pmChicago O'Hare Intl

1h 44m

TYS9:24 pmKnoxville McGhee Tyson

Mar 21

TYS7:40 amKnoxville McGhee Tyson

2h 08m

ORD8:48 amChicago O'Hare Intl

$219

American Airlines

Aug 5

ORD9:40 amChicago O'Hare Intl

1h 45m

TYS12:25 pmKnoxville McGhee Tyson

Aug 8

TYS8:05 amKnoxville McGhee Tyson

2h 04m

ORD9:09 amChicago O'Hare Intl

$224

United Airlines flights from Indiana to Knoxville

Our best United Airlines deals on Indiana to Knoxville flight tickets

United Airlines

Apr 25

ORD7:50 pmChicago O'Hare Intl

1h 44m

TYS10:34 pmKnoxville McGhee Tyson

Apr 27

TYS7:00 amKnoxville McGhee Tyson

1h 55m

ORD7:55 amChicago O'Hare Intl

$199

United Airlines

Apr 3

ORD7:50 pmChicago O'Hare Intl

1h 44m

TYS10:34 pmKnoxville McGhee Tyson

Apr 6

TYS7:00 amKnoxville McGhee Tyson

1h 55m

ORD7:55 amChicago O'Hare Intl

$204

United Airlines

Mar 17

ORD7:35 amChicago O'Hare Intl

1h 44m

TYS10:19 amKnoxville McGhee Tyson

Mar 21

TYS5:43 pmKnoxville McGhee Tyson

2h 04m

ORD6:47 pmChicago O'Hare Intl

$218

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

ter 4/7

8:30 am-11:18 am

Nonstop1h 48m

Knoxville McGhee Tyson

seg 4/13

8:48 pm-9:57 pm

Nonstop2h 09m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

qui 4/9

5:24 pm-8:18 pm

Nonstop1h 54m

Knoxville McGhee Tyson

seg 4/13

8:48 pm-9:57 pm

Nonstop2h 09m

$190

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

sáb 4/25

7:50 pm-10:34 pm

Nonstop1h 44m

Knoxville McGhee Tyson

seg 4/27

7:00 am-7:55 am

Nonstop1h 55m

$199

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

sex 4/3

7:50 pm-10:34 pm

Nonstop1h 44m

Knoxville McGhee Tyson

seg 4/6

7:00 am-7:55 am

Nonstop1h 55m

$204

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

dom 8/16

8:15 am-3:07 pm

1 stop5h 52m

Knoxville McGhee Tyson

sáb 8/22

1:30 pm-7:02 pm

1 stop6h 32m

$209

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

sáb 8/22

12:13 pm-6:17 pm

1 stop6h 04m

Knoxville McGhee Tyson

qua 8/26

7:30 am-1:46 pm

1 stop6h 16m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

ter 4/28

2:40 pm-7:40 pm

1 stop4h 00m

Knoxville McGhee Tyson

qua 4/29

12:50 pm-6:25 pm

1 stop6h 35m

$210

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

ter 4/14

1:27 pm-10:36 am

1 stop20h 09m

Knoxville McGhee Tyson

dom 4/19

11:27 am-9:40 am

2 stops47h 13m

$211

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

ter 4/14

2:40 pm-7:40 pm

1 stop4h 00m

Knoxville McGhee Tyson

qui 4/16

6:35 am-12:50 pm

1 stop7h 15m

$214

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

qui 5/28

7:41 pm-11:37 pm

1 stop26h 56m

Knoxville McGhee Tyson

dom 5/31

1:22 pm-1:57 pm

Nonstop1h 35m

$217

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Indiana, with most prices found around $238. If you aren’t able to travel during the month of July, then book flights to Knoxville from Indiana during November instead. Flights to Knoxville in November, while not as cheap as those in July, still average around $250.

What is the cheapest Indiana to Knoxville McGhee Tyson flight route?

Fly from South Bend/Michiana to Knoxville McGhee Tyson for the best Indiana - Knoxville McGhee Tyson flight prices

What cabin class options are available on Indiana to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Indiana to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Indiana to Knoxville.

Cheap Indiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to Knoxville

Fastest flight time	1h 28m
Direct flights	Every day
Airports in Knoxville	1 airport

The fastest flight from Indiana to Knoxville takes 1h 28m

Direct flights go from Indiana to Knoxville every day.

There is 1 airport in Knoxville. From Indiana there are direct flights to Knoxville McGhee Tyson (TYS).

Search flight deals

When did momondo last update prices for flights from Indiana to Knoxville McGhee Tyson Airport?
Prices for flights from Indiana to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Indiana to Knoxville McGhee Tyson Airport?
As of March 2026, there are 4 operators available to choose from for flights from Indiana to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Indiana to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indiana to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Indiana to Knoxville?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Indiana to Knoxville is Embraer 175 (Enhanced Winglets) (15.38% of total bookings). The next most popular plane models are Embraer 175 (15.38%), Canadair (Bombardier) Regional Jet CRJ-550 (15.38%), and Airbus A320-100/200 (15.38%).

Best airlines flying from Indiana to Knoxville

Compare and see reviews for airlines that fly from Indiana to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $44	Free Cancellation	Rating 7.3 714 reviews	Search Allegiant Air flights
United Airlines	PriceFrom $107	Free Cancellation	Rating 7.4 9,378 reviews	Search United Airlines flights
Delta	PriceFrom $134	Free Cancellation	Rating 7.9 8,242 reviews	Search Delta flights
American Airlines	PriceFrom $208	Free Cancellation	Rating 7.1 11,375 reviews	Search American Airlines flights

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Cherokee

Bryson City

Morristown

Corbin

Maryville

Crossville

Alcoa

Murphy

Oak Ridge

Lenoir City

Kodak

Newport

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Indiana.

Can I find flights from Indiana to Knoxville with flexible booking policies on momondo?

All flight searches from Indiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Indiana to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to Knoxville.

I’m not ready to book a flight from Indiana to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indiana to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Indiana to Knoxville from $54

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to Knoxville departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Indiana to Knoxville

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What cabin class options are available on Indiana to Knoxville McGhee Tyson flights?

Can stopping save me money on Indiana to Knoxville flights?

What is the cheapest airline that flies from Indiana to Knoxville McGhee Tyson?

What airlines fly to Knoxville?

How many flights depart from Indiana to Knoxville on average per week?

How long does it take to fly to Knoxville?

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An easier way to manage your Knoxville trip

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