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Cheap flights from Indiana to Knoxville from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to Knoxville departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Indiana to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
2:48 pm - 5:18 pm
MDW
-
TYS
1h 30mnonstop
Allegiant Air Logo
1:22 pm - 1:58 pm
TYS
-
MDW
1h 36mnonstop
$169Allegiant Air
Thu, Jul 2 - Sun, Jul 5
American Airlines Logo
8:05 am - 10:48 am
ORD
-
TYS
1h 43mnonstop
American Airlines Logo
4:02 pm - 5:04 pm
TYS
-
ORD
2h 02mnonstop
$188American Airlines
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
6:10 pm - 8:52 pm
ORD
-
TYS
1h 42mnonstop
United Airlines Logo
6:45 am - 7:48 am
TYS
-
ORD
2h 03mnonstop
$189United Airlines
Fri, Feb 6 - Mon, Feb 9
United Airlines Logo
7:45 pm - 10:29 pm
ORD
-
TYS
1h 44mnonstop
United Airlines Logo
7:00 am - 7:55 am
TYS
-
ORD
1h 55mnonstop
$197United Airlines
Fri, Apr 3 - Mon, Apr 6
Delta Logo
6:00 am - 11:15 am
SBN
-
TYS
5h 15m
1 stop
Delta Logo
7:46 am - 1:30 pm
TYS
-
SBN
5h 44m
1 stop
$209Delta
Tue, Apr 14 - Sat, Apr 18
Delta Logo
5:59 pm - 11:45 pm
ORD
-
TYS
4h 46m
1 stop
Delta Logo
5:40 am - 10:05 am
TYS
-
ORD
5h 25m
1 stop
$209Delta
Fri, Feb 6 - Sun, Feb 8
Southwest Logo
1:20 pm - 9:10 pm
MDW
-
TYS
6h 50m
2 stops
Southwest Logo
7:25 pm - 12:05 am
TYS
-
MDW
5h 40m
1 stop
$214Southwest
Wed, Mar 11 - Mon, Mar 16
Southwest Logo
2:40 pm - 9:05 pm
ORD
-
TYS
5h 25m
1 stop
Southwest Logo
6:30 am - 12:50 pm
TYS
-
ORD
7h 20m
1 stop
$215Southwest
Sat, Mar 7 - Mon, Mar 9
Multiple Airlines Logo
12:06 pm - 8:18 pm
ORD
-
TYS
7h 12m
1 stop
Multiple Airlines Logo
9:36 pm - 11:22 am
TYS
-
ORD
14h 46m
1 stop
$217Multiple Airlines
Sat, Feb 28 - Mon, Mar 2
Multiple Airlines Logo
7:30 am - 11:05 pm
IND
-
TYS
15h 35m
1 stop
Multiple Airlines Logo
1:39 pm - 9:43 am
TYS
-
IND
44h 04m
2 stops
$229Multiple Airlines
Sun, Jan 25 - Thu, Jan 29

Southwest flights from Indiana to Knoxville

Our best Southwest deals on Indiana to Knoxville flight tickets
Southwest
Mar 11
MDW1:20 pmChicago Midway
6h 50m
2 stops
TYS9:10 pmKnoxville McGhee Tyson
Mar 16
TYS7:25 pmKnoxville McGhee Tyson
5h 40m
1 stop
MDW12:05 amChicago Midway
$214
Southwest
Mar 7
ORD2:40 pmChicago O'Hare Intl
5h 25m
1 stop
TYS9:05 pmKnoxville McGhee Tyson
Mar 9
TYS6:30 amKnoxville McGhee Tyson
7h 20m
1 stop
ORD12:50 pmChicago O'Hare Intl
$215
Southwest
Mar 24
MDW7:45 amChicago Midway
8h 55m
2 stops
TYS5:40 pmKnoxville McGhee Tyson
Mar 25
TYS7:50 amKnoxville McGhee Tyson
6h 05m
2 stops
MDW12:55 pmChicago Midway
$220

American Airlines flights from Indiana to Knoxville

Our best American Airlines deals on Indiana to Knoxville flight tickets
American Airlines
Feb 24
ORD8:05 amChicago O'Hare Intl
1h 43m
TYS10:48 amKnoxville McGhee Tyson
Mar 3
TYS4:02 pmKnoxville McGhee Tyson
2h 02m
ORD5:04 pmChicago O'Hare Intl
$188
American Airlines
Feb 28
ORD3:58 pmChicago O'Hare Intl
1h 39m
TYS6:37 pmKnoxville McGhee Tyson
Mar 7
TYS6:38 pmKnoxville McGhee Tyson
5h 08m
1 stop
ORD10:46 pmChicago O'Hare Intl
$224
American Airlines
Feb 27
ORD1:52 pmChicago O'Hare Intl
1h 39m
TYS4:31 pmKnoxville McGhee Tyson
Mar 2
TYS4:02 pmKnoxville McGhee Tyson
2h 02m
ORD5:04 pmChicago O'Hare Intl
$233

momondo Fare Finder

 
Customize your flight search to find flights from Indiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Indiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 7/2

2:48 pm-5:18 pm

Nonstop1h 30m

Knoxville McGhee Tyson

Sun 7/5

1:22 pm-1:58 pm

Nonstop1h 36m

$169

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 2/24

8:05 am-10:48 am

Nonstop1h 43m

Knoxville McGhee Tyson

Tue 3/3

4:02 pm-5:04 pm

Nonstop2h 02m

$188

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 2/6

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Mon 2/9

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 4/3

7:45 pm-10:29 pm

Nonstop1h 44m

Knoxville McGhee Tyson

Mon 4/6

7:00 am-7:55 am

Nonstop1h 55m

$197

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Tue 4/14

6:00 am-11:15 am

1 stop5h 15m

Knoxville McGhee Tyson

Sat 4/18

7:46 am-1:30 pm

1 stop5h 44m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 2/6

5:59 pm-11:45 pm

1 stop4h 46m

Knoxville McGhee Tyson

Sun 2/8

5:40 am-10:05 am

1 stop5h 25m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 3/11

1:20 pm-9:10 pm

2 stops6h 50m

Knoxville McGhee Tyson

Mon 3/16

7:25 pm-12:05 am

1 stop5h 40m

$214

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 3/7

2:40 pm-9:05 pm

1 stop5h 25m

Knoxville McGhee Tyson

Mon 3/9

6:30 am-12:50 pm

1 stop7h 20m

$215

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 2/28

12:06 pm-8:18 pm

1 stop7h 12m

Knoxville McGhee Tyson

Mon 3/2

9:36 pm-11:22 am

1 stop14h 46m

$217

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 1/25

7:30 am-11:05 pm

1 stop15h 35m

Knoxville McGhee Tyson

Thu 1/29

1:39 pm-9:43 am

2 stops44h 04m

$229

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Indiana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Indiana, with most prices found around $250. If you aren’t able to travel during the month of November, then book flights to Knoxville from Indiana during June instead. Flights to Knoxville in June, while not as cheap as those in November, still average around $254.

What is the cheapest Indiana to Knoxville McGhee Tyson flight route?

Fly from South Bend/Michiana to Knoxville McGhee Tyson for the best Indiana - Knoxville McGhee Tyson flight prices

What cabin class options are available on Indiana to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Indiana to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Indiana to Knoxville.

Cheap Indiana to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to Knoxville

Fastest flight time

1h 28m

Direct flights

Every day

Airports in Knoxville

1 airport
The fastest flight from Indiana to Knoxville takes 1h 28m
Direct flights go from Indiana to Knoxville every day.
There is 1 airport in Knoxville. From Indiana there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • When did momondo last update prices for flights from Indiana to Knoxville McGhee Tyson Airport?

    Prices for flights from Indiana to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Indiana to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Indiana to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indiana to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Indiana to Knoxville?

Best airlines flying from Indiana to Knoxville

Compare and see reviews for airlines that fly from Indiana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $56Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $107Free CancellationRating
7.4
9,143 reviews
Search United Airlines flights
DeltaPriceFrom $134Free CancellationRating
7.9
8,033 reviews
Search Delta flights
American AirlinesPriceFrom $208Free CancellationRating
7.2
11,111 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Indiana.

Can I find flights from Indiana to Knoxville with flexible booking policies on momondo?

All flight searches from Indiana to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Indiana to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to Knoxville.

I’m not ready to book a flight from Indiana to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indiana to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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