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Cheap flights from Hyannis to South Carolina from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Hyannis to South Carolina departing on 9/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Hyannis to South Carolina

Cheap round-trip flights

American Airlines Logo
2:34 pm - 9:15 pmHYA-CLT
6h 41m1 stop
American Airlines Logo
6:15 am - 11:40 amCLT-HYA
5h 25m1 stop
$471American Airlines
Find Deal
Fri, Aug 29 - Tue, Sep 2
American Airlines Logo
2:34 pm - 7:14 pmHYA-CLT
4h 40m1 stop
American Airlines Logo
5:17 am - 2:04 pmCLT-HYA
8h 47m2 stops
$477American Airlines
Find Deal
Fri, Aug 29 - Tue, Sep 2
JetBlue Logo
10:16 am - 5:45 pmHYA-CHS
7h 29m1 stop
JetBlue Logo
8:00 am - 6:45 pmCHS-HYA
10h 45m1 stop
$681JetBlue
Find Deal
Fri, Sep 12 - Sun, Sep 14
American Airlines Logo
2:34 pm - 8:53 pmHYA-CLT
6h 19m2 stops
American Airlines Logo
5:17 am - 2:04 pmCLT-HYA
8h 47m2 stops
$759American Airlines
Find Deal
Fri, Aug 29 - Tue, Sep 2
JetBlue Logo
6:48 am - 12:07 pmHYA-CHS
5h 19m1 stop
JetBlue Logo
12:29 pm - 5:38 pmCHS-HYA
5h 09m1 stop
$775JetBlue
Find Deal
Sat, Oct 4 - Wed, Oct 8
Logo
8:55 am - 8:05 amHYA-CLT
23h 10m3 stops
Logo
11:00 am - 12:06 pmCLT-HYA
25h 06m2 stops
$829
Find Deal
Fri, Aug 29 - Tue, Sep 2
Logo
12:54 pm - 3:49 pmHYA-CHS
26h 55m2 stops
Logo
6:00 am - 5:38 pmCHS-HYA
11h 38m2 stops
$845
Find Deal
Fri, Sep 12 - Sun, Sep 14
Logo
8:55 am - 8:05 amHYA-CLT
23h 10m3 stops
Logo
3:10 pm - 8:27 pmCLT-HYA
29h 17m3 stops
$871
Find Deal
Fri, Aug 29 - Tue, Sep 2

American Airlines flights from Hyannis to South Carolina

Our best American Airlines deals on Hyannis to South Carolina flight tickets
American Airlines
Aug 29
HYA2:34 pmHyannis Barnstable
6h 41m
1 stop
CLT9:15 pmCharlotte Douglas
Sep 2
CLT6:15 amCharlotte Douglas
5h 25m
1 stop
HYA11:40 amHyannis Barnstable
$471
Find similar
American Airlines
Aug 29
HYA2:34 pmHyannis Barnstable
4h 40m
1 stop
CLT7:14 pmCharlotte Douglas
Sep 2
CLT5:17 amCharlotte Douglas
8h 47m
2 stops
HYA2:04 pmHyannis Barnstable
$477
Find similar
American Airlines
Aug 29
HYA2:34 pmHyannis Barnstable
6h 19m
2 stops
CLT8:53 pmCharlotte Douglas
Sep 2
CLT5:17 amCharlotte Douglas
8h 47m
2 stops
HYA2:04 pmHyannis Barnstable
$759
Find similar

JetBlue flights from Hyannis to South Carolina

Our best JetBlue deals on Hyannis to South Carolina flight tickets
JetBlue
Sep 12
HYA10:16 amHyannis Barnstable
7h 29m
1 stop
CHS5:45 pmCharleston
Sep 14
CHS8:00 amCharleston
10h 45m
1 stop
HYA6:45 pmHyannis Barnstable
$681
Find similar
JetBlue
Oct 4
HYA6:48 amHyannis Barnstable
5h 19m
1 stop
CHS12:07 pmCharleston
Oct 8
CHS12:29 pmCharleston
5h 09m
1 stop
HYA5:38 pmHyannis Barnstable
$775
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Hyannis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Hyannis to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Fri 8/29

2:34 pm-9:15 pm

1 stop6h 41m

Charlotte Douglas

Tue 9/2

6:15 am-11:40 am

1 stop5h 25m

$471

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Fri 8/29

2:34 pm-7:14 pm

1 stop4h 40m

Charlotte Douglas

Tue 9/2

5:17 am-2:04 pm

2 stops8h 47m

$477

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 9/12

10:16 am-5:45 pm

1 stop7h 29m

Charleston

Sun 9/14

8:00 am-6:45 pm

1 stop10h 45m

$681

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Fri 8/29

2:34 pm-8:53 pm

2 stops6h 19m

Charlotte Douglas

Tue 9/2

5:17 am-2:04 pm

2 stops8h 47m

$759

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sat 10/4

6:48 am-12:07 pm

1 stop5h 19m

Charleston

Wed 10/8

12:29 pm-5:38 pm

1 stop5h 09m

$775

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Fri 8/29

8:55 am-8:05 am

3 stops23h 10m

Charlotte Douglas

Tue 9/2

11:00 am-12:06 pm

2 stops25h 06m

$829

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 9/12

12:54 pm-3:49 pm

2 stops26h 55m

Charleston

Sun 9/14

6:00 am-5:38 pm

2 stops11h 38m

$845

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Fri 8/29

8:55 am-8:05 am

3 stops23h 10m

Charlotte Douglas

Tue 9/2

3:10 pm-8:27 pm

3 stops29h 17m

$871

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sun 9/28

10:16 am-5:45 pm

1 stop7h 29m

$178

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Tue 9/16

6:15 am-10:59 pm

3 stops16h 44m

$326

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Hyannis to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Hyannis Barnstable to South Carolina?

JetBlue is the most popular carrier operating from Hyannis Barnstable to South Carolina

What airlines fly to South Carolina?

Spirit Airlines, JetBlue and Delta are the top three most popular airlines that fly to South Carolina from Hyannis according to our data. Spirit Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 8 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Hyannis to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Hyannis to South Carolina

Best Price Found

$178

Fastest flight time

4h 40m

Direct flights

None

Airports in South Carolina

2 airports
The best one-way flight to South Carolina from Hyannis in the past 72 hours is $178. The best round-trip flight deal from Hyannis to South Carolina found on momondo in the last 72 hours is $471.
The fastest flight from Hyannis to South Carolina takes 4h 40m
There are no direct flights from Hyannis to South Carolina. Popular non-direct routes for this connection are Hyannis Barnstable Airport - Charlotte Douglas Airport and Hyannis Barnstable Airport - Charleston Airport.
There are 2 airports near South Carolina: Charlotte Douglas (CLT), Charleston (CHS)
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  • When did momondo last update prices for flights from Hyannis Barnstable Airport to South Carolina?

    Prices for flights from Hyannis Barnstable Airport to South Carolina are updated daily.

  • How old do you have to be to fly from Hyannis Barnstable Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Hyannis Barnstable Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Hyannis to South Carolina?

Finding the right flight to South Carolina from Hyannis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from Hyannis to South Carolina with flexible booking policies on momondo?

All flight searches from Hyannis to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Hyannis to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Hyannis to South Carolina.

I’m not ready to book a flight from Hyannis to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Hyannis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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