Cheap flights from Houston to South America from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to South America departing on 9/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:24 am - 2:30 pm
IAH
-
MDE
7h 06m
1 stop
JetBlue Logo
1:30 pm - 11:02 pm
MDE
-
IAH
9h 32m
1 stop
$368JetBlue
Mon, Sep 14 - Wed, Sep 16
JetBlue Logo
7:24 am - 2:45 pm
IAH
-
MDE
7h 21m
1 stop
JetBlue Logo
1:30 pm - 11:02 pm
MDE
-
IAH
9h 32m
1 stop
$402JetBlue
Thu, Aug 27 - Thu, Sep 17
American Airlines Logo
8:23 pm - 2:17 pm
HOU
-
CTG
17h 54m
2 stops
American Airlines Logo
3:17 pm - 9:48 am
CTG
-
HOU
18h 31m
2 stops
$474American Airlines
Fri, Jul 10 - Thu, Jul 16
American Airlines Logo
8:23 pm - 2:17 pm
HOU
-
CTG
17h 54m
2 stops
American Airlines Logo
3:17 pm - 9:48 am
CTG
-
HOU
18h 31m
2 stops
$559American Airlines
Fri, Jul 10 - Thu, Jul 16
Azul Logo
12:25 pm - 2:10 pm
IAH
-
GIG
23h 45m
2 stops
Azul Logo
1:20 pm - 10:50 am
GIG
-
IAH
23h 30m
2 stops
$862Azul
Tue, Aug 25 - Mon, Aug 31
Delta Logo
11:00 am - 6:59 pm
HOU
-
UIO
7h 59m
1 stop
Delta Logo
12:59 am - 4:30 pm
UIO
-
HOU
15h 31m
1 stop
$897Delta
Mon, Sep 21 - Sun, Oct 18
Delta Logo
6:00 am - 6:59 pm
HOU
-
UIO
12h 59m
1 stop
Delta Logo
9:00 am - 10:35 pm
UIO
-
HOU
13h 35m
2 stops
$902Delta
Tue, Sep 15 - Tue, Sep 22
Azul Logo
2:28 pm - 2:10 pm
IAH
-
GIG
21h 42m
2 stops
Azul Logo
1:20 pm - 10:50 am
GIG
-
IAH
23h 30m
2 stops
$903Azul
Tue, Aug 18 - Tue, Aug 25
LATAM Airlines Logo
10:50 am - 5:00 am
HOU
-
LIM
18h 10m
1 stop
LATAM Airlines Logo
12:05 pm - 10:01 am
LIM
-
HOU
21h 56m
1 stop
$946LATAM Airlines
Mon, Aug 31 - Mon, Sep 14
LATAM Airlines Logo
6:00 am - 6:59 pm
HOU
-
UIO
12h 59m
1 stop
LATAM Airlines Logo
12:59 am - 12:16 pm
UIO
-
HOU
11h 17m
1 stop
$997LATAM Airlines
Mon, Aug 17 - Sat, Aug 29

Viva flights from Houston to South America

Our best Viva deals on Houston to South America flight tickets
Viva
Nov 15
IAH8:50 amHouston George Bush Intcntl
14h 55m
1 stop
BOG12:45 amBogotá El Dorado
Nov 21
BOG1:45 amBogotá El Dorado
20h 15m
1 stop
IAH9:00 pmHouston George Bush Intcntl
$405
Viva
Sep 14
IAH10:25 amHouston George Bush Intcntl
13h 40m
1 stop
BOG12:05 amBogotá El Dorado
Sep 22
BOG1:45 amBogotá El Dorado
20h 15m
1 stop
IAH10:00 pmHouston George Bush Intcntl
$407
Viva
Nov 18
IAH10:10 pmHouston George Bush Intcntl
25h 35m
1 stop
BOG12:45 amBogotá El Dorado
Feb 9
BOG1:45 amBogotá El Dorado
20h 15m
1 stop
IAH9:00 pmHouston George Bush Intcntl
$416

American Airlines flights from Houston to South America

Our best American Airlines deals on Houston to South America flight tickets
American Airlines
Jul 10
HOU8:23 pmHouston Hobby
17h 54m
2 stops
CTG2:17 pmCartagena Rafael Nunez
Jul 16
CTG3:17 pmCartagena Rafael Nunez
18h 31m
2 stops
HOU9:48 amHouston Hobby
$474
American Airlines
Jul 10
HOU8:23 pmHouston Hobby
17h 54m
2 stops
CTG2:17 pmCartagena Rafael Nunez
Jul 16
CTG3:17 pmCartagena Rafael Nunez
18h 31m
2 stops
HOU9:48 amHouston Hobby
$559
American Airlines
Aug 3
HOU8:23 pmHouston Hobby
17h 54m
2 stops
CTG2:17 pmCartagena Rafael Nunez
Aug 11
CTG3:15 pmCartagena Rafael Nunez
17h 47m
2 stops
HOU9:02 amHouston Hobby
$562

momondo Fare Finder

 
Customize your flight search to find flights from Houston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 2, 2026.
Use the filters below to find and compare flights from Houston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Mon 9/14

7:24 am-2:30 pm

1 stop7h 06m

Medellín Jose Maria Cordova Intl

Wed 9/16

1:30 pm-11:02 pm

1 stop9h 32m

$368

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Thu 8/27

7:24 am-2:45 pm

1 stop7h 21m

Medellín Jose Maria Cordova Intl

Thu 9/17

1:30 pm-11:02 pm

1 stop9h 32m

$402

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 7/10

8:23 pm-2:17 pm

2 stops17h 54m

Cartagena Rafael Nunez

Thu 7/16

3:17 pm-9:48 am

2 stops18h 31m

$474

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 7/10

8:23 pm-2:17 pm

2 stops17h 54m

Cartagena Rafael Nunez

Thu 7/16

3:17 pm-9:48 am

2 stops18h 31m

$559

HoustonRio de Janeiro

IAH - GIG

IAHGIG

Houston George Bush Intcntl

Tue 8/25

12:25 pm-2:10 pm

2 stops23h 45m

Rio de Janeiro–Galeão Intl

Mon 8/31

1:20 pm-10:50 am

2 stops23h 30m

$862

HoustonQuito

HOU - UIO

HOUUIO

Houston Hobby

Mon 9/21

11:00 am-6:59 pm

1 stop7h 59m

Quito Mariscal Sucr

Sun 10/18

12:59 am-4:30 pm

1 stop15h 31m

$897

HoustonQuito

HOU - UIO

HOUUIO

Houston Hobby

Tue 9/15

6:00 am-6:59 pm

1 stop12h 59m

Quito Mariscal Sucr

Tue 9/22

9:00 am-10:35 pm

2 stops13h 35m

$902

HoustonRio de Janeiro

IAH - GIG

IAHGIG

Houston George Bush Intcntl

Tue 8/18

2:28 pm-2:10 pm

2 stops21h 42m

Rio de Janeiro–Galeão Intl

Tue 8/25

1:20 pm-10:50 am

2 stops23h 30m

$903

HoustonLima

HOU - LIM

HOULIM

Houston Hobby

Mon 8/31

10:50 am-5:00 am

1 stop18h 10m

Lima J Chavez Intl

Mon 9/14

12:05 pm-10:01 am

1 stop21h 56m

$946

HoustonQuito

HOU - UIO

HOUUIO

Houston Hobby

Mon 8/17

6:00 am-6:59 pm

1 stop12h 59m

Quito Mariscal Sucr

Sat 8/29

12:59 am-12:16 pm

1 stop11h 17m

$997

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, March is the cheapest month to fly from Houston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $790. If you aren’t able to travel during the month of March, then book flights to South America from Houston during February instead. Flights to South America in February, while not as cheap as those in March, still average around $835.

What is the cheapest Houston to South America flight route?

Fly from Houston George Bush Intcntl to Lima J Chavez Intl for the best Houston - South America flight prices

How far in advance should I book a flight from Houston to South America?

You are more likely to see cheaper flights to South America from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $796 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston for as low as $678 on momondo.

What cabin class options are available on Houston to South America flights?

There are 3 cabin classes available to choose from on Houston to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to South America

Fastest flight time

4h 35m

Direct flights

Every day

Airports in South America

464 airports
The fastest flight from Houston to South America takes 4h 35m
Direct flights go from Houston to South America every day.
There are 464 airports in South America. From Houston there are direct flights to Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE).

Frequently asked questions about flying from Houston to South America

  • When did momondo last update prices for flights from Houston to South America?

    Prices for flights from Houston to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to South America?

  • How old do you have to be to fly from Houston to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to South America

Compare and see reviews for airlines that fly from Houston to South America with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $127Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
VivaPriceFrom $176Free CancellationRating
7.0
804 reviews
Search Viva flights
VolarisPriceFrom $217Free CancellationRating
6.5
1,157 reviews
Search Volaris flights
AviancaPriceFrom $218Free CancellationRating
6.5
2,527 reviews
Search Avianca flights
DeltaPriceFrom $433Free CancellationRating
7.9
8,398 reviews
Search Delta flights
LATAM AirlinesPriceFrom $442Free CancellationRating
7.4
1,920 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $546Free CancellationRating
7.4
9,778 reviews
Search United Airlines flights
AeromexicoPriceFrom $871Free CancellationRating
7.4
1,499 reviews
Search Aeromexico flights
Copa AirlinesPriceFrom $893Free CancellationRating
7.5
1,567 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

Flights from Houston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to South America?

momondo helps you find the best flight between Houston and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
Thu 7/2
Thu 7/9

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Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo