Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Houston to South America from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to South America departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Houston to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
12:14 pm - 12:56 amIAH-MDE
11h 42m2 stops
Spirit Airlines Logo
11:50 am - 12:57 amMDE-IAH
14h 07m2 stops
$297Spirit Airlines
Find Deal
Tue, Dec 2 - Thu, Dec 11
Multiple Airlines Logo
6:05 pm - 2:16 pmIAH-MDE
19h 11m2 stops
Multiple Airlines Logo
3:11 pm - 12:37 pmMDE-IAH
22h 26m1 stop
$300Multiple Airlines
Find Deal
Sun, Feb 1 - Fri, Feb 6
American Airlines Logo
6:31 pm - 12:10 pmHOU-CTG
17h 39m2 stops
American Airlines Logo
3:25 pm - 8:39 amCTG-HOU
17h 14m2 stops
$519American Airlines
Find Deal
Fri, Apr 24 - Fri, May 1
American Airlines Logo
4:55 pm - 1:30 pmHOU-CTG
19h 35m2 stops
American Airlines Logo
2:30 pm - 10:05 amCTG-HOU
20h 35m2 stops
$520American Airlines
Find Deal
Tue, Jan 6 - Tue, Jan 13
Delta Logo
5:35 am - 2:17 pmHOU-CTG
7h 42m1 stop
Delta Logo
3:32 pm - 10:35 pmCTG-HOU
8h 03m1 stop
$566Delta
Find Deal
Wed, Jan 7 - Wed, Jan 14
Delta Logo
6:00 am - 8:01 pmHOU-CTG
13h 01m2 stops
Delta Logo
4:35 am - 10:48 pmCTG-HOU
19h 13m2 stops
$614Delta
Find Deal
Wed, Nov 26 - Tue, Dec 2
LATAM Airlines Logo
11:09 am - 2:17 pmHOU-CTG
26h 08m1 stop
LATAM Airlines Logo
3:32 pm - 10:35 pmCTG-HOU
8h 03m1 stop
$690LATAM Airlines
Find Deal
Thu, Jan 8 - Sat, Jan 17
LATAM Airlines Logo
6:00 am - 2:17 pmHOU-CTG
7h 17m1 stop
LATAM Airlines Logo
3:32 pm - 10:48 pmCTG-HOU
8h 16m1 stop
$697LATAM Airlines
Find Deal
Thu, Dec 11 - Thu, Dec 18
Avianca Logo
5:40 pm - 12:10 amIAH-EZE
28h 30m2 stops
Avianca Logo
4:45 pm - 4:10 pmEZE-IAH
25h 25m2 stops
$836Avianca
Find Deal
Mon, Mar 30 - Tue, Apr 14
Avianca Logo
5:35 pm - 3:50 pmIAH-EZE
20h 15m2 stops
Avianca Logo
4:55 pm - 12:05 pmEZE-IAH
21h 10m2 stops
$844Avianca
Find Deal
Sun, Mar 15 - Fri, Mar 20

Spirit Airlines flights from Houston to South America

Our best Spirit Airlines deals on Houston to South America flight tickets
Spirit Airlines
Dec 2
IAH12:14 pmHouston George Bush Intcntl
11h 42m
2 stops
MDE12:56 amMedellín Jose Maria Cordova Intl
Dec 11
MDE11:50 amMedellín Jose Maria Cordova Intl
14h 07m
2 stops
IAH12:57 amHouston George Bush Intcntl
$297
Find similar
Spirit Airlines
Dec 8
IAH10:41 amHouston George Bush Intcntl
23h 14m
2 stops
MDE10:55 amMedellín Jose Maria Cordova Intl
Dec 10
MDE2:05 amMedellín Jose Maria Cordova Intl
8h 13m
1 stop
IAH9:18 amHouston George Bush Intcntl
$301
Find similar
Spirit Airlines
Dec 6
IAH10:41 amHouston George Bush Intcntl
13h 28m
1 stop
MDE1:09 amMedellín Jose Maria Cordova Intl
Dec 13
MDE11:50 amMedellín Jose Maria Cordova Intl
14h 07m
2 stops
IAH12:57 amHouston George Bush Intcntl
$302
Find similar

Delta flights from Houston to South America

Our best Delta deals on Houston to South America flight tickets
Delta
Jan 7
HOU5:35 amHouston Hobby
7h 42m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Jan 14
CTG3:32 pmCartagena Rafael Nunez
8h 03m
1 stop
HOU10:35 pmHouston Hobby
$566
Find similar
Delta
Nov 26
HOU6:00 amHouston Hobby
13h 01m
2 stops
CTG8:01 pmCartagena Rafael Nunez
Dec 2
CTG4:35 amCartagena Rafael Nunez
19h 13m
2 stops
HOU10:48 pmHouston Hobby
$614
Find similar
Delta
Apr 24
HOU5:35 pmHouston Hobby
19h 43m
1 stop
CTG1:18 pmCartagena Rafael Nunez
May 1
CTG5:16 amCartagena Rafael Nunez
16h 22m
2 stops
HOU9:38 pmHouston Hobby
$700
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Houston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Tue 12/2

12:14 pm-12:56 am

2 stops11h 42m

Medellín Jose Maria Cordova Intl

Thu 12/11

11:50 am-12:57 am

2 stops14h 07m

$297

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Sun 2/1

6:05 pm-2:16 pm

2 stops19h 11m

Medellín Jose Maria Cordova Intl

Fri 2/6

3:11 pm-12:37 pm

1 stop22h 26m

$300

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 4/24

6:31 pm-12:10 pm

2 stops17h 39m

Cartagena Rafael Nunez

Fri 5/1

3:25 pm-8:39 am

2 stops17h 14m

$519

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Tue 1/6

4:55 pm-1:30 pm

2 stops19h 35m

Cartagena Rafael Nunez

Tue 1/13

2:30 pm-10:05 am

2 stops20h 35m

$520

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Wed 1/7

5:35 am-2:17 pm

1 stop7h 42m

Cartagena Rafael Nunez

Wed 1/14

3:32 pm-10:35 pm

1 stop8h 03m

$566

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Wed 11/26

6:00 am-8:01 pm

2 stops13h 01m

Cartagena Rafael Nunez

Tue 12/2

4:35 am-10:48 pm

2 stops19h 13m

$614

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Thu 1/8

11:09 am-2:17 pm

1 stop26h 08m

Cartagena Rafael Nunez

Sat 1/17

3:32 pm-10:35 pm

1 stop8h 03m

$690

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Thu 12/11

6:00 am-2:17 pm

1 stop7h 17m

Cartagena Rafael Nunez

Thu 12/18

3:32 pm-10:48 pm

1 stop8h 16m

$697

HoustonBuenos Aires

IAH - EZE

IAHEZE

Houston George Bush Intcntl

Mon 3/30

5:40 pm-12:10 am

2 stops28h 30m

Buenos Aires Ministro Pistarini

Tue 4/14

4:45 pm-4:10 pm

2 stops25h 25m

$836

HoustonBuenos Aires

IAH - EZE

IAHEZE

Houston George Bush Intcntl

Sun 3/15

5:35 pm-3:50 pm

2 stops20h 15m

Buenos Aires Ministro Pistarini

Fri 3/20

4:55 pm-12:05 pm

2 stops21h 10m

$844

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

How to get the cheapest flight ticket from Houston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from Houston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $585. If you aren’t able to travel during the month of May, then book flights to South America from Houston during July instead. Flights to South America in July, while not as cheap as those in May, still average around $686.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Houston to South America is on a Wednesday when prices can be found for as low as $766. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Houston to South America for around $928.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Houston to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $823. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,190 on average. Flights to South America from Houston at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Houston to South America flight route?

Fly from Houston George Bush Intcntl to Lima J Chavez Intl for the best Houston - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $786 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston for as low as $501 on momondo.

What cabin class options are available on Houston to South America flights?

There are 3 cabin classes available to choose from on Houston to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to South America

Fastest flight time

4h 43m

Direct flights

Every day

Airports in South America

2 airports
The fastest flight from Houston to South America takes 4h 43m
Direct flights go from Houston to South America every day.
There are 2 airports near South America: Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE)
Search flight deals

  • When did momondo last update prices for flights from Houston to South America?

    Prices for flights from Houston to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to South America?

  • How old do you have to be to fly from Houston to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to South America

Compare and see reviews for airlines that fly from Houston to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $188Free CancellationRating
6.3
8,115 reviews
Search Spirit Airlines flights
VolarisPriceFrom $290Free CancellationRating
6.7
1,150 reviews
Search Volaris flights
AviancaPriceFrom $307Free CancellationRating
6.6
2,468 reviews
Search Avianca flights
American AirlinesPriceFrom $320Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights
DeltaPriceFrom $378Free CancellationRating
7.9
7,994 reviews
Search Delta flights
LATAM AirlinesPriceFrom $493Free CancellationRating
7.5
1,871 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $587Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $739Free CancellationRating
7.4
9,001 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

Flights from Houston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to South America?

momondo helps you find the best flight between Houston and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 11/28
Fri 12/5
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $264
Flights to Buenos Airesfrom $472
Flights to Bogotáfrom $182
Flights to Sao Paulofrom $380
Flights to Rio de Janeirofrom $421
Flights to Medellínfrom $162
Flights to Santiagofrom $373
Flights to Cartagenafrom $175
Flights to Quitofrom $314
Flights to Cuscofrom $408
Flights to Guayaquilfrom $233
Flights to Califrom $186