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Cheap flights from Houston to South America from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to South America departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:59 am - 12:56 amIAH-MDE
15h 57m2 stops
Multiple Airlines Logo
2:05 am - 9:18 amMDE-IAH
8h 13m1 stop
$321Multiple Airlines
Find Deal
mié., dic. 3 - mar., dic. 9
Multiple Airlines Logo
5:25 pm - 9:00 amIAH-MDE
14h 35m1 stop
Multiple Airlines Logo
11:50 pm - 4:08 pmMDE-IAH
17h 18m1 stop
$322Multiple Airlines
Find Deal
sáb., dic. 6 - mar., dic. 9
Spirit Airlines Logo
4:06 pm - 1:09 amIAH-MDE
32h 03m2 stops
Spirit Airlines Logo
3:10 pm - 9:18 amMDE-IAH
19h 08m1 stop
$323Spirit Airlines
Find Deal
sáb., dic. 6 - lun., dic. 8
Spirit Airlines Logo
10:41 am - 1:09 amIAH-MDE
13h 28m1 stop
Spirit Airlines Logo
3:10 pm - 12:57 amMDE-IAH
10h 47m1 stop
$325Spirit Airlines
Find Deal
jue., dic. 4 - sáb., dic. 6
American Airlines Logo
6:36 pm - 1:30 pmHOU-CTG
17h 54m2 stops
American Airlines Logo
4:30 pm - 10:05 amCTG-HOU
18h 35m2 stops
$499American Airlines
Find Deal
mar., feb. 3 - mar., feb. 10
American Airlines Logo
8:27 pm - 2:10 pmHOU-CTG
17h 43m2 stops
American Airlines Logo
3:25 pm - 8:39 amCTG-HOU
17h 14m2 stops
$519American Airlines
Find Deal
vie., abr. 24 - vie., may. 1
Delta Logo
5:45 am - 2:17 pmHOU-CTG
7h 32m1 stop
Delta Logo
3:32 pm - 10:33 pmCTG-HOU
8h 01m1 stop
$566Delta
Find Deal
mié., ene. 21 - mié., ene. 28
Delta Logo
11:09 am - 12:31 amHOU-CTG
12h 22m2 stops
Delta Logo
3:32 pm - 10:33 pmCTG-HOU
8h 01m1 stop
$572Delta
Find Deal
mié., ene. 21 - mié., ene. 28
LATAM Airlines Logo
6:00 am - 8:55 pmHOU-LIM
14h 55m2 stops
LATAM Airlines Logo
11:50 am - 9:32 amLIM-HOU
21h 42m2 stops
$788LATAM Airlines
Find Deal
lun., mar. 9 - mar., mar. 24
LATAM Airlines Logo
11:09 am - 2:30 pmHOU-SCL
24h 21m3 stops
LATAM Airlines Logo
6:30 pm - 10:21 amSCL-HOU
18h 51m2 stops
$969LATAM Airlines
Find Deal
jue., ene. 8 - mié., ene. 21

Spirit Airlines flights from Houston to South America

Our best Spirit Airlines deals on Houston to South America flight tickets
Spirit Airlines
Dec 6
IAH4:06 pmHouston George Bush Intcntl
32h 03m
2 stops
MDE1:09 amMedellín Jose Maria Cordova Intl
Dec 8
MDE3:10 pmMedellín Jose Maria Cordova Intl
19h 08m
1 stop
IAH9:18 amHouston George Bush Intcntl
$323
Find similar
Spirit Airlines
Dec 4
IAH10:41 amHouston George Bush Intcntl
13h 28m
1 stop
MDE1:09 amMedellín Jose Maria Cordova Intl
Dec 6
MDE3:10 pmMedellín Jose Maria Cordova Intl
10h 47m
1 stop
IAH12:57 amHouston George Bush Intcntl
$325
Find similar
Spirit Airlines
Dec 5
IAH7:25 pmHouston George Bush Intcntl
17h 44m
1 stop
BOG2:09 pmBogotá El Dorado
Jan 27
BOG3:06 pmBogotá El Dorado
9h 52m
1 stop
IAH11:58 pmHouston George Bush Intcntl
$326
Find similar

Delta flights from Houston to South America

Our best Delta deals on Houston to South America flight tickets
Delta
Jan 21
HOU5:45 amHouston Hobby
7h 32m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Jan 28
CTG3:32 pmCartagena Rafael Nunez
8h 01m
1 stop
HOU10:33 pmHouston Hobby
$566
Find similar
Delta
Jan 21
HOU11:09 amHouston Hobby
12h 22m
2 stops
CTG12:31 amCartagena Rafael Nunez
Jan 28
CTG3:32 pmCartagena Rafael Nunez
8h 01m
1 stop
HOU10:33 pmHouston Hobby
$572
Find similar
Delta
Feb 28
HOU5:25 amHouston Hobby
7h 50m
1 stop
CTG2:15 pmCartagena Rafael Nunez
Mar 9
CTG2:30 pmCartagena Rafael Nunez
19h 02m
1 stop
HOU9:32 amHouston Hobby
$599
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 19, 2025.
Use the filters below to find and compare flights from Houston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

mié. 12/3

7:59 am-12:56 am

2 stops15h 57m

Medellín Jose Maria Cordova Intl

mar. 12/9

2:05 am-9:18 am

1 stop8h 13m

$321

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

sáb. 12/6

5:25 pm-9:00 am

1 stop14h 35m

Medellín Jose Maria Cordova Intl

mar. 12/9

11:50 pm-4:08 pm

1 stop17h 18m

$322

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

sáb. 12/6

4:06 pm-1:09 am

2 stops32h 03m

Medellín Jose Maria Cordova Intl

lun. 12/8

3:10 pm-9:18 am

1 stop19h 08m

$323

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

jue. 12/4

10:41 am-1:09 am

1 stop13h 28m

Medellín Jose Maria Cordova Intl

sáb. 12/6

3:10 pm-12:57 am

1 stop10h 47m

$325

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mar. 2/3

6:36 pm-1:30 pm

2 stops17h 54m

Cartagena Rafael Nunez

mar. 2/10

4:30 pm-10:05 am

2 stops18h 35m

$499

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

vie. 4/24

8:27 pm-2:10 pm

2 stops17h 43m

Cartagena Rafael Nunez

vie. 5/1

3:25 pm-8:39 am

2 stops17h 14m

$519

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mié. 1/21

5:45 am-2:17 pm

1 stop7h 32m

Cartagena Rafael Nunez

mié. 1/28

3:32 pm-10:33 pm

1 stop8h 01m

$566

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mié. 1/21

11:09 am-12:31 am

2 stops12h 22m

Cartagena Rafael Nunez

mié. 1/28

3:32 pm-10:33 pm

1 stop8h 01m

$572

HoustonLima

HOU - LIM

HOULIM

Houston Hobby

lun. 3/9

6:00 am-8:55 pm

2 stops14h 55m

Lima J Chavez Intl

mar. 3/24

11:50 am-9:32 am

2 stops21h 42m

$788

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

jue. 1/8

11:09 am-2:30 pm

3 stops24h 21m

Santiago Arturo Merino Benitez

mié. 1/21

6:30 pm-10:21 am

2 stops18h 51m

$969

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from Houston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $597. If you aren’t able to travel during the month of May, then book flights to South America from Houston during January instead. Flights to South America in January, while not as cheap as those in May, still average around $677.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Houston to South America is on a Wednesday when prices can be found for as low as $766. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Houston to South America for around $928.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Houston to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $823. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,190 on average. Flights to South America from Houston at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Houston to South America flight route?

Fly from Houston George Bush Intcntl to Lima J Chavez Intl for the best Houston - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $768 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston for as low as $567 on momondo.

What cabin class options are available on Houston to South America flights?

There are 3 cabin classes available to choose from on Houston to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to South America

Fastest flight time

4h 43m

Direct flights

Every day

Airports in South America

2 airports
The fastest flight from Houston to South America takes 4h 43m
Direct flights go from Houston to South America every day.
There are 2 airports near South America: Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE)
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  • When did momondo last update prices for flights from Houston to South America?

    Prices for flights from Houston to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to South America?

  • How old do you have to be to fly from Houston to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to South America

Compare and see reviews for airlines that fly from Houston to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $188Free CancellationRating
6.3
8,151 reviews
Search Spirit Airlines flights
VolarisPriceFrom $290Free CancellationRating
6.7
1,150 reviews
Search Volaris flights
AviancaPriceFrom $307Free CancellationRating
6.6
2,475 reviews
Search Avianca flights
American AirlinesPriceFrom $320Free CancellationRating
7.2
11,044 reviews
Search American Airlines flights
DeltaPriceFrom $378Free CancellationRating
7.9
8,003 reviews
Search Delta flights
LATAM AirlinesPriceFrom $551Free CancellationRating
7.5
1,878 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $587Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $739Free CancellationRating
7.4
9,019 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

Flights from Houston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to South America?

momondo helps you find the best flight between Houston and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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1 adult
vie. 12/19
vie. 12/26
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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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