Cheap flights from Houston to South America from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to South America departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:45 am - 1:22 pm
IAH
-
MDE
7h 37m
1 stop
Spirit Airlines Logo
2:17 pm - 11:59 pm
MDE
-
IAH
9h 42m
1 stop
$298Spirit Airlines
Mon, Mar 30 - Tue, Apr 14
Spirit Airlines Logo
5:45 am - 1:11 pm
IAH
-
BOG
7h 26m
1 stop
Spirit Airlines Logo
2:10 pm - 10:18 am
BOG
-
IAH
20h 08m
2 stops
$303Spirit Airlines
Thu, Mar 19 - Tue, Apr 7
Multiple Airlines Logo
12:02 pm - 12:21 am
IAH
-
MDE
12h 19m
1 stop
Multiple Airlines Logo
1:17 am - 6:13 pm
MDE
-
IAH
16h 56m
1 stop
$313Multiple Airlines
Sat, Apr 11 - Sun, Apr 12
Multiple Airlines Logo
3:24 pm - 12:16 am
IAH
-
MDE
8h 52m
1 stop
Multiple Airlines Logo
2:06 pm - 8:27 am
MDE
-
IAH
42h 21m
2 stops
$315Multiple Airlines
Mon, Apr 20 - Fri, May 1
American Airlines Logo
8:21 pm - 12:09 pm
HOU
-
CTG
15h 48m
2 stops
American Airlines Logo
3:10 pm - 9:26 am
CTG
-
HOU
18h 16m
2 stops
$512American Airlines
Fri, Apr 24 - Fri, May 1
American Airlines Logo
8:21 pm - 2:04 pm
HOU
-
CTG
17h 43m
2 stops
American Airlines Logo
3:10 pm - 9:26 am
CTG
-
HOU
18h 16m
2 stops
$533American Airlines
Fri, Apr 24 - Fri, May 1
LATAM Airlines Logo
6:00 am - 1:15 pm
HOU
-
CTG
7h 15m
1 stop
LATAM Airlines Logo
2:30 pm - 10:42 pm
CTG
-
HOU
8h 12m
1 stop
$639LATAM Airlines
Tue, Mar 24 - Thu, Apr 2
Delta Logo
6:00 am - 1:40 pm
HOU
-
BOG
7h 40m
1 stop
Delta Logo
9:00 am - 10:26 pm
BOG
-
HOU
13h 26m
1 stop
$895Delta
Thu, Apr 30 - Mon, May 11
Delta Logo
6:00 am - 8:10 pm
HOU
-
BOG
14h 10m
2 stops
Delta Logo
11:00 am - 9:27 am
BOG
-
HOU
22h 27m
2 stops
$900Delta
Thu, Apr 30 - Mon, May 11
LATAM Airlines Logo
10:05 am - 1:40 pm
HOU
-
BOG
27h 35m
1 stop
LATAM Airlines Logo
2:55 pm - 9:20 am
BOG
-
HOU
18h 25m
1 stop
$934LATAM Airlines
Mon, Jun 29 - Fri, Jul 17

Spirit Airlines flights from Houston to South America

Our best Spirit Airlines deals on Houston to South America flight tickets
Spirit Airlines
Mar 30
IAH5:45 amHouston George Bush Intcntl
7h 37m
1 stop
MDE1:22 pmMedellín Jose Maria Cordova Intl
Apr 14
MDE2:17 pmMedellín Jose Maria Cordova Intl
9h 42m
1 stop
IAH11:59 pmHouston George Bush Intcntl
$298
Spirit Airlines
Mar 19
IAH5:45 amHouston George Bush Intcntl
7h 26m
1 stop
BOG1:11 pmBogotá El Dorado
Apr 7
BOG2:10 pmBogotá El Dorado
20h 08m
2 stops
IAH10:18 amHouston George Bush Intcntl
$303
Spirit Airlines
May 26
IAH5:11 pmHouston George Bush Intcntl
7h 05m
1 stop
MDE12:16 amMedellín Jose Maria Cordova Intl
Jun 2
MDE2:06 pmMedellín Jose Maria Cordova Intl
9h 42m
1 stop
IAH11:48 pmHouston George Bush Intcntl
$305

Delta flights from Houston to South America

Our best Delta deals on Houston to South America flight tickets
Delta
Mar 24
HOU6:00 amHouston Hobby
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Mar 31
CTG4:25 amCartagena Rafael Nunez
18h 17m
2 stops
HOU10:42 pmHouston Hobby
$642
Delta
Mar 24
HOU6:00 amHouston Hobby
18h 31m
2 stops
CTG12:31 amCartagena Rafael Nunez
Apr 2
CTG2:30 pmCartagena Rafael Nunez
8h 12m
1 stop
HOU10:42 pmHouston Hobby
$646
Delta
Mar 25
HOU11:33 amHouston Hobby
12h 58m
2 stops
CTG12:31 amCartagena Rafael Nunez
Apr 1
CTG5:30 amCartagena Rafael Nunez
17h 12m
2 stops
HOU10:42 pmHouston Hobby
$648

momondo Fare Finder

 
Customize your flight search to find flights from Houston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Houston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Mon 3/30

5:45 am-1:22 pm

1 stop7h 37m

Medellín Jose Maria Cordova Intl

Tue 4/14

2:17 pm-11:59 pm

1 stop9h 42m

$298

HoustonBogotá

IAH - BOG

IAHBOG

Houston George Bush Intcntl

Thu 3/19

5:45 am-1:11 pm

1 stop7h 26m

Bogotá El Dorado

Tue 4/7

2:10 pm-10:18 am

2 stops20h 08m

$303

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Sat 4/11

12:02 pm-12:21 am

1 stop12h 19m

Medellín Jose Maria Cordova Intl

Sun 4/12

1:17 am-6:13 pm

1 stop16h 56m

$313

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Mon 4/20

3:24 pm-12:16 am

1 stop8h 52m

Medellín Jose Maria Cordova Intl

Fri 5/1

2:06 pm-8:27 am

2 stops42h 21m

$315

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 4/24

8:21 pm-12:09 pm

2 stops15h 48m

Cartagena Rafael Nunez

Fri 5/1

3:10 pm-9:26 am

2 stops18h 16m

$512

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 4/24

8:21 pm-2:04 pm

2 stops17h 43m

Cartagena Rafael Nunez

Fri 5/1

3:10 pm-9:26 am

2 stops18h 16m

$533

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Tue 3/24

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Thu 4/2

2:30 pm-10:42 pm

1 stop8h 12m

$639

HoustonBogotá

HOU - BOG

HOUBOG

Houston Hobby

Thu 4/30

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Mon 5/11

9:00 am-10:26 pm

1 stop13h 26m

$895

HoustonBogotá

HOU - BOG

HOUBOG

Houston Hobby

Thu 4/30

6:00 am-8:10 pm

2 stops14h 10m

Bogotá El Dorado

Mon 5/11

11:00 am-9:27 am

2 stops22h 27m

$900

HoustonBogotá

HOU - BOG

HOUBOG

Houston Hobby

Mon 6/29

10:05 am-1:40 pm

1 stop27h 35m

Bogotá El Dorado

Fri 7/17

2:55 pm-9:20 am

1 stop18h 25m

$934

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, July is the cheapest month to fly from Houston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $687. If you aren’t able to travel during the month of July, then book flights to South America from Houston during June instead. Flights to South America in June, while not as cheap as those in July, still average around $697.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Houston to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $928. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,515 on average. Flights to South America from Houston at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Houston to South America flight route?

Fly from Houston George Bush Intcntl to Lima J Chavez Intl for the best Houston - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $754 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston for as low as $668 on momondo.

What cabin class options are available on Houston to South America flights?

There are 3 cabin classes available to choose from on Houston to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to South America

Fastest flight time

4h 43m

Direct flights

Every day

Airports in South America

463 airports
The fastest flight from Houston to South America takes 4h 43m
Direct flights go from Houston to South America every day.
There are 463 airports in South America. From Houston there are direct flights to Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE).
  • When did momondo last update prices for flights from Houston to South America?

    Prices for flights from Houston to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to South America?

  • How old do you have to be to fly from Houston to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to South America

Compare and see reviews for airlines that fly from Houston to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $151Free CancellationRating
6.3
8,493 reviews
Search Spirit Airlines flights
AviancaPriceFrom $281Free CancellationRating
6.5
2,495 reviews
Search Avianca flights
VolarisPriceFrom $290Free CancellationRating
6.6
1,172 reviews
Search Volaris flights
American AirlinesPriceFrom $337Free CancellationRating
7.1
11,367 reviews
Search American Airlines flights
DeltaPriceFrom $724Free CancellationRating
7.9
8,244 reviews
Search Delta flights
United AirlinesPriceFrom $740Free CancellationRating
7.4
9,362 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $769Free CancellationRating
7.5
1,557 reviews
Search Copa Airlines flights
GOLPriceFrom $787Free CancellationRating
7.3
1,176 reviews
Search GOL flights
LATAM AirlinesPriceFrom $949Free CancellationRating
7.5
1,925 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $1,165Free CancellationRating
7.4
1,574 reviews
Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

Flights from Houston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to South America?

momondo helps you find the best flight between Houston and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
Sun 3/29
Sun 4/5

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Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo