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Cheap flights from Houston to South America from $98

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to South America departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Houston to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
8:19 pm - 1:55 pm
IAH
-
MDE
16h 36m1 stop
Spirit Airlines Logo
2:50 pm - 11:34 pm
MDE
-
IAH
9h 44m1 stop
$314Spirit Airlines
Thu, Jan 15 - Thu, Jan 22
Multiple Airlines Logo
4:35 pm - 9:40 pm
IAH
-
MDE
28h 05m1 stop
Multiple Airlines Logo
1:00 pm - 11:58 pm
MDE
-
IAH
11h 58m1 stop
$322Multiple Airlines
Thu, Jan 15 - Thu, Jan 22
Spirit Airlines Logo
6:55 pm - 1:57 pm
IAH
-
MDE
18h 02m2 stops
Spirit Airlines Logo
3:15 pm - 8:40 am
MDE
-
IAH
18h 25m1 stop
$323Spirit Airlines
Tue, Dec 30 - Fri, Jan 16
Spirit Airlines Logo
5:46 am - 2:15 pm
IAH
-
MDE
7h 29m1 stop
Spirit Airlines Logo
2:50 pm - 6:22 pm
MDE
-
IAH
28h 32m3 stops
$327Spirit Airlines
Wed, Jan 28 - Thu, Feb 5
American Airlines Logo
6:36 pm - 1:30 pm
HOU
-
CTG
17h 54m2 stops
American Airlines Logo
4:30 pm - 10:05 am
CTG
-
HOU
18h 35m2 stops
$487American Airlines
Mon, Jan 26 - Mon, Feb 2
American Airlines Logo
6:31 pm - 12:10 pm
HOU
-
CTG
17h 39m2 stops
American Airlines Logo
3:25 pm - 9:30 am
CTG
-
HOU
18h 05m2 stops
$499American Airlines
Fri, Apr 24 - Fri, May 1
Delta Logo
5:45 am - 2:17 pm
HOU
-
CTG
7h 32m1 stop
Delta Logo
3:32 pm - 10:21 am
CTG
-
HOU
19h 49m1 stop
$559Delta
Mon, Jan 26 - Mon, Feb 2
Delta Logo
1:06 pm - 5:00 am
HOU
-
LIM
14h 54m1 stop
Delta Logo
11:40 pm - 4:32 pm
LIM
-
HOU
16h 52m1 stop
$746Delta
Thu, Mar 5 - Tue, Mar 17
LATAM Airlines Logo
11:09 am - 5:00 am
HOU
-
LIM
16h 51m2 stops
LATAM Airlines Logo
8:25 am - 10:33 pm
LIM
-
HOU
15h 08m2 stops
$759LATAM Airlines
Wed, Jan 21 - Tue, Feb 3
LATAM Airlines Logo
10:05 am - 10:00 pm
HOU
-
LIM
11h 55m2 stops
LATAM Airlines Logo
12:15 am - 9:38 pm
LIM
-
HOU
21h 23m2 stops
$786LATAM Airlines
Mon, May 4 - Thu, May 14

Spirit Airlines flights from Houston to South America

Our best Spirit Airlines deals on Houston to South America flight tickets
Spirit Airlines
Jan 15
IAH8:19 pmHouston George Bush Intcntl
16h 36m
1 stop
MDE1:55 pmMedellín Jose Maria Cordova Intl
Jan 22
MDE2:50 pmMedellín Jose Maria Cordova Intl
9h 44m
1 stop
IAH11:34 pmHouston George Bush Intcntl
$314
Find similar
Spirit Airlines
Dec 30
IAH6:55 pmHouston George Bush Intcntl
18h 02m
2 stops
MDE1:57 pmMedellín Jose Maria Cordova Intl
Jan 16
MDE3:15 pmMedellín Jose Maria Cordova Intl
18h 25m
1 stop
IAH8:40 amHouston George Bush Intcntl
$323
Find similar
Spirit Airlines
Jan 28
IAH5:46 amHouston George Bush Intcntl
7h 29m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Feb 5
MDE2:50 pmMedellín Jose Maria Cordova Intl
28h 32m
3 stops
IAH6:22 pmHouston George Bush Intcntl
$327
Find similar

Delta flights from Houston to South America

Our best Delta deals on Houston to South America flight tickets
Delta
Jan 26
HOU5:45 amHouston Hobby
7h 32m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Feb 2
CTG3:32 pmCartagena Rafael Nunez
19h 49m
1 stop
HOU10:21 amHouston Hobby
$559
Find similar
Delta
Jan 26
HOU11:09 amHouston Hobby
12h 22m
2 stops
CTG12:31 amCartagena Rafael Nunez
Feb 2
CTG3:32 pmCartagena Rafael Nunez
19h 49m
1 stop
HOU10:21 amHouston Hobby
$565
Find similar
Delta
Feb 23
HOU5:25 amHouston Hobby
7h 52m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Mar 3
CTG4:35 amCartagena Rafael Nunez
18h 53m
2 stops
HOU10:28 pmHouston Hobby
$569
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Houston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Thu 1/15

8:19 pm-1:55 pm

1 stop16h 36m

Medellín Jose Maria Cordova Intl

Thu 1/22

2:50 pm-11:34 pm

1 stop9h 44m

$314

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Thu 1/15

4:35 pm-9:40 pm

1 stop28h 05m

Medellín Jose Maria Cordova Intl

Thu 1/22

1:00 pm-11:58 pm

1 stop11h 58m

$322

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Tue 12/30

6:55 pm-1:57 pm

2 stops18h 02m

Medellín Jose Maria Cordova Intl

Fri 1/16

3:15 pm-8:40 am

1 stop18h 25m

$323

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

Wed 1/28

5:46 am-2:15 pm

1 stop7h 29m

Medellín Jose Maria Cordova Intl

Thu 2/5

2:50 pm-6:22 pm

3 stops28h 32m

$327

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Mon 1/26

6:36 pm-1:30 pm

2 stops17h 54m

Cartagena Rafael Nunez

Mon 2/2

4:30 pm-10:05 am

2 stops18h 35m

$487

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 4/24

6:31 pm-12:10 pm

2 stops17h 39m

Cartagena Rafael Nunez

Fri 5/1

3:25 pm-9:30 am

2 stops18h 05m

$499

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Mon 1/26

5:45 am-2:17 pm

1 stop7h 32m

Cartagena Rafael Nunez

Mon 2/2

3:32 pm-10:21 am

1 stop19h 49m

$559

HoustonLima

HOU - LIM

HOULIM

Houston Hobby

Thu 3/5

1:06 pm-5:00 am

1 stop14h 54m

Lima J Chavez Intl

Tue 3/17

11:40 pm-4:32 pm

1 stop16h 52m

$746

HoustonLima

HOU - LIM

HOULIM

Houston Hobby

Wed 1/21

11:09 am-5:00 am

2 stops16h 51m

Lima J Chavez Intl

Tue 2/3

8:25 am-10:33 pm

2 stops15h 08m

$759

HoustonLima

HOU - LIM

HOULIM

Houston Hobby

Mon 5/4

10:05 am-10:00 pm

2 stops11h 55m

Lima J Chavez Intl

Thu 5/14

12:15 am-9:38 pm

2 stops21h 23m

$786

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from Houston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $615. If you aren’t able to travel during the month of May, then book flights to South America from Houston during January instead. Flights to South America in January, while not as cheap as those in May, still average around $677.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Houston to South America is on a Wednesday when prices can be found for as low as $766. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Houston to South America for around $928.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Houston to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $823. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,190 on average. Flights to South America from Houston at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Houston to South America flight route?

Fly from Houston George Bush Intcntl to Lima J Chavez Intl for the best Houston - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $768 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston for as low as $577 on momondo.

What cabin class options are available on Houston to South America flights?

There are 3 cabin classes available to choose from on Houston to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to South America

Fastest flight time

4h 43m

Direct flights

Every day

Airports in South America

2 airports
The fastest flight from Houston to South America takes 4h 43m
Direct flights go from Houston to South America every day.
There are 2 airports near South America: Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE)
Search flight deals

  • When did momondo last update prices for flights from Houston to South America?

    Prices for flights from Houston to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to South America?

  • How old do you have to be to fly from Houston to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to South America

Compare and see reviews for airlines that fly from Houston to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $188Free CancellationRating
6.3
8,161 reviews
Search Spirit Airlines flights
VolarisPriceFrom $290Free CancellationRating
6.7
1,156 reviews
Search Volaris flights
AviancaPriceFrom $307Free CancellationRating
6.6
2,476 reviews
Search Avianca flights
American AirlinesPriceFrom $320Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $551Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
DeltaPriceFrom $724Free CancellationRating
7.9
8,011 reviews
Search Delta flights
United AirlinesPriceFrom $739Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $942Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
AeromexicoPriceFrom $1,165Free CancellationRating
7.4
1,653 reviews
Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

Flights from Houston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to South America?

momondo helps you find the best flight between Houston and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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