Cheap flights from Houston to South America from $117

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to South America departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:45 am - 1:22 pm
IAH
-
MDE
7h 37m
1 stop
Spirit Airlines Logo
2:17 pm - 8:40 am
MDE
-
IAH
18h 23m
1 stop
$296Spirit Airlines
lun., mar. 23 - sáb., abr. 4
Spirit Airlines Logo
4:22 pm - 12:42 am
IAH
-
MDE
8h 20m
1 stop
Spirit Airlines Logo
2:10 pm - 11:59 pm
MDE
-
IAH
9h 49m
1 stop
$297Spirit Airlines
jue., may. 28 - mar., jun. 2
Multiple Airlines Logo
11:42 am - 12:21 am
IAH
-
MDE
12h 39m
1 stop
Multiple Airlines Logo
1:17 am - 5:53 pm
MDE
-
IAH
16h 36m
1 stop
$300Multiple Airlines
vie., abr. 10 - sáb., abr. 11
Multiple Airlines Logo
5:49 pm - 1:13 pm
IAH
-
MDE
19h 24m
2 stops
Multiple Airlines Logo
1:37 am - 11:59 am
MDE
-
IAH
10h 22m
1 stop
$306Multiple Airlines
vie., abr. 24 - sáb., abr. 25
American Airlines Logo
8:21 pm - 2:04 pm
HOU
-
CTG
17h 43m
2 stops
American Airlines Logo
3:10 pm - 9:26 am
CTG
-
HOU
18h 16m
2 stops
$512American Airlines
vie., abr. 24 - vie., may. 1
LATAM Airlines Logo
6:00 am - 1:15 pm
HOU
-
CTG
7h 15m
1 stop
LATAM Airlines Logo
2:30 pm - 10:42 pm
CTG
-
HOU
8h 12m
1 stop
$581LATAM Airlines
mar., mar. 10 - mar., mar. 17
LATAM Airlines Logo
6:00 am - 1:15 pm
HOU
-
CTG
7h 15m
1 stop
LATAM Airlines Logo
2:30 pm - 1:28 pm
CTG
-
HOU
22h 58m
1 stop
$604LATAM Airlines
dom., mar. 22 - lun., abr. 6
Delta Logo
11:33 am - 11:17 pm
HOU
-
CTG
11h 44m
2 stops
Delta Logo
2:30 pm - 10:42 pm
CTG
-
HOU
8h 12m
1 stop
$616Delta
mar., mar. 10 - mar., mar. 17
American Airlines Logo
4:21 pm - 1:30 pm
HOU
-
CTG
20h 09m
2 stops
American Airlines Logo
3:15 pm - 9:43 am
CTG
-
HOU
18h 28m
2 stops
$624American Airlines
mar., mar. 3 - mar., mar. 10
Delta Logo
11:33 am - 12:31 am
HOU
-
CTG
12h 58m
2 stops
Delta Logo
2:30 pm - 10:42 pm
CTG
-
HOU
8h 12m
1 stop
$626Delta
mar., mar. 10 - mar., mar. 17

Spirit Airlines flights from Houston to South America

Our best Spirit Airlines deals on Houston to South America flight tickets
Spirit Airlines
Mar 23
IAH5:45 amHouston George Bush Intcntl
7h 37m
1 stop
MDE1:22 pmMedellín Jose Maria Cordova Intl
Apr 4
MDE2:17 pmMedellín Jose Maria Cordova Intl
18h 23m
1 stop
IAH8:40 amHouston George Bush Intcntl
$296
Spirit Airlines
May 28
IAH4:22 pmHouston George Bush Intcntl
8h 20m
1 stop
MDE12:42 amMedellín Jose Maria Cordova Intl
Jun 2
MDE2:06 pmMedellín Jose Maria Cordova Intl
18h 39m
1 stop
IAH8:45 amHouston George Bush Intcntl
$297
Spirit Airlines
Mar 13
IAH4:22 pmHouston George Bush Intcntl
7h 59m
1 stop
MDE12:21 amMedellín Jose Maria Cordova Intl
Apr 11
MDE2:17 pmMedellín Jose Maria Cordova Intl
9h 42m
1 stop
IAH11:59 pmHouston George Bush Intcntl
$298

LATAM Airlines flights from Houston to South America

Our best LATAM Airlines deals on Houston to South America flight tickets
LATAM Airlines
Mar 10
HOU6:00 amHouston Hobby
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Mar 17
CTG2:30 pmCartagena Rafael Nunez
8h 12m
1 stop
HOU10:42 pmHouston Hobby
$581
LATAM Airlines
Mar 22
HOU6:00 amHouston Hobby
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Apr 6
CTG2:30 pmCartagena Rafael Nunez
22h 58m
1 stop
HOU1:28 pmHouston Hobby
$604
LATAM Airlines
Mar 10
HOU6:00 amHouston Hobby
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Mar 17
CTG2:30 pmCartagena Rafael Nunez
8h 12m
1 stop
HOU10:42 pmHouston Hobby
$619

momondo Fare Finder

 
Customize your flight search to find flights from Houston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated febrero 12, 2026.
Use the filters below to find and compare flights from Houston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

lun. 3/23

5:45 am-1:22 pm

1 stop7h 37m

Medellín Jose Maria Cordova Intl

sáb. 4/4

2:17 pm-8:40 am

1 stop18h 23m

$296

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

jue. 5/28

4:22 pm-12:42 am

1 stop8h 20m

Medellín Jose Maria Cordova Intl

mar. 6/2

2:10 pm-11:59 pm

1 stop9h 49m

$297

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

vie. 4/10

11:42 am-12:21 am

1 stop12h 39m

Medellín Jose Maria Cordova Intl

sáb. 4/11

1:17 am-5:53 pm

1 stop16h 36m

$300

HoustonMedellín

IAH - MDE

IAHMDE

Houston George Bush Intcntl

vie. 4/24

5:49 pm-1:13 pm

2 stops19h 24m

Medellín Jose Maria Cordova Intl

sáb. 4/25

1:37 am-11:59 am

1 stop10h 22m

$306

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

vie. 4/24

8:21 pm-2:04 pm

2 stops17h 43m

Cartagena Rafael Nunez

vie. 5/1

3:10 pm-9:26 am

2 stops18h 16m

$512

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mar. 3/10

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

mar. 3/17

2:30 pm-10:42 pm

1 stop8h 12m

$581

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

dom. 3/22

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

lun. 4/6

2:30 pm-1:28 pm

1 stop22h 58m

$604

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mar. 3/10

11:33 am-11:17 pm

2 stops11h 44m

Cartagena Rafael Nunez

mar. 3/17

2:30 pm-10:42 pm

1 stop8h 12m

$616

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mar. 3/3

4:21 pm-1:30 pm

2 stops20h 09m

Cartagena Rafael Nunez

mar. 3/10

3:15 pm-9:43 am

2 stops18h 28m

$624

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

mar. 3/10

11:33 am-12:31 am

2 stops12h 58m

Cartagena Rafael Nunez

mar. 3/17

2:30 pm-10:42 pm

1 stop8h 12m

$626

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from Houston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $610. If you aren’t able to travel during the month of May, then book flights to South America from Houston during April instead. Flights to South America in April, while not as cheap as those in May, still average around $672.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Houston to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $934. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,515 on average. Flights to South America from Houston at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Houston to South America flight route?

Fly from Houston George Bush Intcntl to Bogotá El Dorado for the best Houston - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $742 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston for as low as $662 on momondo.

What cabin class options are available on Houston to South America flights?

There are 3 cabin classes available to choose from on Houston to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to South America

Fastest flight time

4h 43m

Direct flights

Every day

Airports in South America

463 airports
The fastest flight from Houston to South America takes 4h 43m
Direct flights go from Houston to South America every day.
There are 463 airports in South America. From Houston there are direct flights to Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE).
  • When did momondo last update prices for flights from Houston to South America?

    Prices for flights from Houston to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to South America?

  • How old do you have to be to fly from Houston to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to South America

Compare and see reviews for airlines that fly from Houston to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $180Free CancellationRating
6.3
8,448 reviews
Search Spirit Airlines flights
AviancaPriceFrom $281Free CancellationRating
6.5
2,496 reviews
Search Avianca flights
VolarisPriceFrom $290Free CancellationRating
6.6
1,174 reviews
Search Volaris flights
American AirlinesPriceFrom $337Free CancellationRating
7.2
11,277 reviews
Search American Airlines flights
DeltaPriceFrom $724Free CancellationRating
7.9
8,187 reviews
Search Delta flights
United AirlinesPriceFrom $740Free CancellationRating
7.4
9,283 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $769Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $785Free CancellationRating
7.5
1,920 reviews
Search LATAM Airlines flights
GOLPriceFrom $787Free CancellationRating
7.3
1,170 reviews
Search GOL flights
AeromexicoPriceFrom $1,165Free CancellationRating
7.4
1,576 reviews
Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

Flights from Houston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to South America?

momondo helps you find the best flight between Houston and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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1 adult
sáb. 3/14
sáb. 3/21

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