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Cheap flights from Florence, South Carolina to San Francisco Bay Area from $249

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to San Francisco Bay Area departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Florence, South Carolina to San Francisco Bay Area

Cheap round-trip flights

American Airlines Logo
11:11 am - 7:16 pmFLO-SFO
11h 05m1 stop
American Airlines Logo
12:32 am - 10:13 amSFO-FLO
6h 41m1 stop
$507American Airlines
Find Deal
Wed, Mar 4 - Fri, Mar 6
American Airlines Logo
2:33 pm - 12:28 amFLO-SFO
12h 55m2 stops
American Airlines Logo
12:32 am - 10:13 amSFO-FLO
6h 41m1 stop
$512American Airlines
Find Deal
Wed, Mar 4 - Fri, Mar 6
American Airlines Logo
2:33 pm - 11:59 pmFLO-SFO
12h 26m2 stops
American Airlines Logo
7:22 pm - 9:24 amSFO-FLO
11h 02m2 stops
$517American Airlines
Find Deal
Wed, Mar 4 - Sat, Mar 7
American Airlines Logo
3:19 pm - 8:44 pmFLO-SFO
8h 25m1 stop
American Airlines Logo
10:15 pm - 10:46 amSFO-FLO
9h 31m1 stop
$528American Airlines
Find Deal
Wed, Oct 8 - Sun, Oct 12
American Airlines Logo
3:19 pm - 9:56 pmFLO-SFO
9h 37m1 stop
American Airlines Logo
7:39 pm - 10:46 amSFO-FLO
12h 07m2 stops
$533American Airlines
Find Deal
Wed, Oct 8 - Sun, Oct 12
American Airlines Logo
6:14 am - 3:18 pmFLO-SFO
12h 04m2 stops
American Airlines Logo
7:39 pm - 10:46 amSFO-FLO
12h 07m2 stops
$538American Airlines
Find Deal
Wed, Oct 8 - Sun, Oct 12
American Airlines Logo
2:33 pm - 5:14 pmFLO-SFO
29h 41m2 stops
American Airlines Logo
6:02 am - 9:24 amSFO-FLO
24h 22m2 stops
$765American Airlines
Find Deal
Wed, Mar 4 - Sat, Mar 7

American Airlines flights from Florence, South Carolina to San Francisco Bay Area

Our best American Airlines deals on Florence, South Carolina to San Francisco Bay Area flight tickets
American Airlines
Mar 4
FLO11:11 amFlorence
11h 05m
1 stop
SFO7:16 pmSan Francisco
Mar 6
SFO12:32 amSan Francisco
6h 41m
1 stop
FLO10:13 amFlorence
$507
Find similar
American Airlines
Mar 4
FLO2:33 pmFlorence
12h 55m
2 stops
SFO12:28 amSan Francisco
Mar 6
SFO12:32 amSan Francisco
6h 41m
1 stop
FLO10:13 amFlorence
$512
Find similar
American Airlines
Mar 4
FLO2:33 pmFlorence
12h 26m
2 stops
SFO11:59 pmSan Francisco
Mar 7
SFO7:22 pmSan Francisco
11h 02m
2 stops
FLO9:24 amFlorence
$517
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 24, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to San Francisco Bay Area that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 3/4

11:11 am-7:16 pm

1 stop11h 05m

San Francisco

Fri 3/6

12:32 am-10:13 am

1 stop6h 41m

$507

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 3/4

2:33 pm-12:28 am

2 stops12h 55m

San Francisco

Fri 3/6

12:32 am-10:13 am

1 stop6h 41m

$512

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 3/4

2:33 pm-11:59 pm

2 stops12h 26m

San Francisco

Sat 3/7

7:22 pm-9:24 am

2 stops11h 02m

$517

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 10/8

3:19 pm-8:44 pm

1 stop8h 25m

San Francisco

Sun 10/12

10:15 pm-10:46 am

1 stop9h 31m

$528

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 10/8

3:19 pm-9:56 pm

1 stop9h 37m

San Francisco

Sun 10/12

7:39 pm-10:46 am

2 stops12h 07m

$533

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 10/8

6:14 am-3:18 pm

2 stops12h 04m

San Francisco

Sun 10/12

7:39 pm-10:46 am

2 stops12h 07m

$538

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 3/4

2:33 pm-5:14 pm

2 stops29h 41m

San Francisco

Sat 3/7

6:02 am-9:24 am

2 stops24h 22m

$765

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 10/15

3:19 pm-9:56 pm

1 stop9h 37m

$249

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 10/15

6:14 am-3:18 pm

2 stops12h 04m

$254

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Florence, South Carolina to San Francisco Bay Area

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florence, South Carolina to San Francisco Bay Area flights?

You could potentially save up to 53% on your flight if you consider stops on a Florence, South Carolina to San Francisco Bay Area flight.

Cheap Florence, South Carolina to San Francisco Bay Area flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to San Francisco Bay Area

Direct flights

None
There are no direct flights from Florence, South Carolina to San Francisco Bay Area. There are no popular flight routes from Florence, South Carolina to San Francisco Bay Area.
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  • When did momondo last update prices for flights from Florence Airport to San Francisco Bay Area?

    Prices for flights from Florence Airport to San Francisco Bay Area refresh daily.

  • How many operators does momondo search for flights from Florence Airport to San Francisco Bay Area?

  • How old do you have to be to fly from Florence Airport to San Francisco Bay Area?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florence Airport to San Francisco Bay Area.

  • What documentation or ID do you need to fly to San Francisco Bay Area?

    The required travel and health documents for your San Francisco Bay Area trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Bay Area. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Florence, South Carolina to San Francisco Bay Area?

Best airlines flying from Florence, South Carolina to San Francisco Bay Area

Compare and see reviews for airlines that fly from Florence, South Carolina to San Francisco Bay Area with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $326Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

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Why should I use momondo to find a flight deal from Florence to San Francisco Bay Area?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Florence to San Francisco Bay Area. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Florence to San Francisco Bay Area with flexible booking policies on momondo?

All flight searches from Florence to San Francisco Bay Area on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Florence to San Francisco Bay Area?

momondo helps you find the best flight between Florence and San Francisco Bay Area by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florence to San Francisco Bay Area right now. Can momondo alert me if prices change?

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