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Cheap flights from Florence, South Carolina to San Francisco Bay Area from $457

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to San Francisco Bay Area departing on 9/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Florence, South Carolina to San Francisco Bay Area

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:09 am - 9:47 am
FLO
-
SFO
7h 38m
1 stop
American Airlines Logo
12:00 pm - 10:58 pm
SFO
-
FLO
7h 58m
1 stop
$457American Airlines
Sun, Sep 20 - Sat, Sep 26
American Airlines Logo
5:09 am - 9:47 am
FLO
-
SFO
7h 38m
1 stop
American Airlines Logo
7:00 am - 10:58 pm
SFO
-
FLO
12h 58m
2 stops
$570American Airlines
Sun, Sep 20 - Sat, Sep 26
American Airlines Logo
2:35 pm - 10:07 pm
FLO
-
SFO
10h 32m
1 stop
American Airlines Logo
1:20 pm - 11:37 pm
SFO
-
FLO
7h 17m
1 stop
$572American Airlines
Fri, Jul 3 - Tue, Jul 7
American Airlines Logo
2:35 pm - 10:07 pm
FLO
-
SFO
10h 32m
1 stop
American Airlines Logo
9:08 am - 11:37 pm
SFO
-
FLO
11h 29m
2 stops
$663American Airlines
Fri, Jul 3 - Tue, Jul 7
American Airlines Logo
2:35 pm - 8:06 pm
FLO
-
SFO
8h 31m
1 stop
American Airlines Logo
1:20 pm - 11:37 pm
SFO
-
FLO
7h 17m
1 stop
$723American Airlines
Mon, Jul 13 - Sun, Jul 19
American Airlines Logo
5:09 am - 3:36 pm
FLO
-
SFO
13h 27m
2 stops
American Airlines Logo
7:00 am - 10:58 pm
SFO
-
FLO
12h 58m
2 stops
$778American Airlines
Sun, Sep 20 - Sat, Sep 26
American Airlines Logo
5:17 am - 12:19 pm
FLO
-
SFO
10h 02m
1 stop
American Airlines Logo
1:20 pm - 11:37 pm
SFO
-
FLO
7h 17m
1 stop
$786American Airlines
Sun, Jul 5 - Thu, Jul 9
American Airlines Logo
2:35 pm - 8:06 pm
FLO
-
SFO
8h 31m
1 stop
American Airlines Logo
1:20 pm - 11:37 pm
SFO
-
FLO
7h 17m
1 stop
$802American Airlines
Mon, Jul 6 - Fri, Jul 10
American Airlines Logo
5:17 am - 3:34 pm
FLO
-
SFO
13h 17m
2 stops
American Airlines Logo
8:00 am - 11:37 pm
SFO
-
FLO
12h 37m
2 stops
$851American Airlines
Fri, Jul 3 - Tue, Jul 7
American Airlines Logo
5:17 am - 3:34 pm
FLO
-
SFO
13h 17m
2 stops
American Airlines Logo
1:20 pm - 11:37 pm
SFO
-
FLO
7h 17m
1 stop
$899American Airlines
Mon, Jul 13 - Sun, Jul 19

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American Airlines flights from Florence, South Carolina to San Francisco Bay Area

Our best American Airlines deals on Florence, South Carolina to San Francisco Bay Area flight tickets
American Airlines
Sep 20
FLO5:09 amFlorence
7h 38m
1 stop
SFO9:47 amSan Francisco
Sep 26
SFO12:00 pmSan Francisco
7h 58m
1 stop
FLO10:58 pmFlorence
$457
American Airlines
Sep 20
FLO5:09 amFlorence
7h 38m
1 stop
SFO9:47 amSan Francisco
Sep 26
SFO7:00 amSan Francisco
12h 58m
2 stops
FLO10:58 pmFlorence
$570
American Airlines
Jul 3
FLO2:35 pmFlorence
10h 32m
1 stop
SFO10:07 pmSan Francisco
Jul 7
SFO1:20 pmSan Francisco
7h 17m
1 stop
FLO11:37 pmFlorence
$572

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 22, 2026.
Use the filters below to find and compare flights from Florence, South Carolina to San Francisco Bay Area that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Sun 9/20

5:09 am-9:47 am

1 stop7h 38m

San Francisco

Sat 9/26

12:00 pm-10:58 pm

1 stop7h 58m

$457

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Sun 9/20

5:09 am-9:47 am

1 stop7h 38m

San Francisco

Sat 9/26

7:00 am-10:58 pm

2 stops12h 58m

$570

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Fri 7/3

2:35 pm-10:07 pm

1 stop10h 32m

San Francisco

Tue 7/7

1:20 pm-11:37 pm

1 stop7h 17m

$572

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Fri 7/3

2:35 pm-10:07 pm

1 stop10h 32m

San Francisco

Tue 7/7

9:08 am-11:37 pm

2 stops11h 29m

$663

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Mon 7/13

2:35 pm-8:06 pm

1 stop8h 31m

San Francisco

Sun 7/19

1:20 pm-11:37 pm

1 stop7h 17m

$723

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Sun 9/20

5:09 am-3:36 pm

2 stops13h 27m

San Francisco

Sat 9/26

7:00 am-10:58 pm

2 stops12h 58m

$778

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Sun 7/5

5:17 am-12:19 pm

1 stop10h 02m

San Francisco

Thu 7/9

1:20 pm-11:37 pm

1 stop7h 17m

$786

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Mon 7/6

2:35 pm-8:06 pm

1 stop8h 31m

San Francisco

Fri 7/10

1:20 pm-11:37 pm

1 stop7h 17m

$802

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Fri 7/3

5:17 am-3:34 pm

2 stops13h 17m

San Francisco

Tue 7/7

8:00 am-11:37 pm

2 stops12h 37m

$851

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Mon 7/13

5:17 am-3:34 pm

2 stops13h 17m

San Francisco

Sun 7/19

1:20 pm-11:37 pm

1 stop7h 17m

$899

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Francisco Bay Area from

How to get the cheapest flight ticket from Florence, South Carolina to San Francisco Bay Area

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florence, South Carolina to San Francisco Bay Area flights?

You could potentially save up to 57% on your flight if you consider stops on a Florence, South Carolina to San Francisco Bay Area flight.

Cheap Florence, South Carolina to San Francisco Bay Area flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to San Francisco Bay Area

Fastest flight time

7h 38m

Direct flights

None
The fastest flight from Florence, South Carolina to San Francisco Bay Area takes 7h 38m
There are no direct flights from Florence, South Carolina to San Francisco Bay Area. There are no popular flight routes from Florence, South Carolina to San Francisco Bay Area.
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Frequently asked questions about flying from Florence, South Carolina to San Francisco Bay Area

  • When did momondo last update prices for flights from Florence Airport to San Francisco Bay Area?

    Prices for flights from Florence Airport to San Francisco Bay Area refresh daily.

  • How old do you have to be to fly from Florence Airport to San Francisco Bay Area?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florence Airport to San Francisco Bay Area.

  • What documentation or ID do you need to fly to San Francisco Bay Area?

    The required travel and health documents for your San Francisco Bay Area trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Bay Area. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Florence, South Carolina to San Francisco Bay Area?

Why use momondo?

Why should I use momondo to find a flight deal from Florence to San Francisco Bay Area?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Florence to San Francisco Bay Area. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Florence to San Francisco Bay Area with flexible booking policies on momondo?

All flight searches from Florence to San Francisco Bay Area on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Florence to San Francisco Bay Area?

momondo helps you find the best flight between Florence and San Francisco Bay Area by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florence to San Francisco Bay Area right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco Bay Area from Florence are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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