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Cheap flights from Florence, South Carolina to Ohio from $303

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Ohio departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Florence, South Carolina to Ohio

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:31 pm - 12:22 amFLO-DTW
5h 51m1 stop
American Airlines Logo
12:00 pm - 6:05 pmDTW-FLO
6h 05m1 stop
$303American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
American Airlines Logo
5:15 am - 1:40 pmFLO-DTW
8h 25m2 stops
American Airlines Logo
7:40 pm - 12:03 amDTW-FLO
4h 23m1 stop
$308American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
American Airlines Logo
11:16 am - 8:00 pmFLO-DTW
8h 44m2 stops
American Airlines Logo
9:40 am - 6:05 pmDTW-FLO
8h 25m2 stops
$313American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
American Airlines Logo
7:00 am - 10:50 amFLO-CVG
27h 50m2 stops
American Airlines Logo
7:10 am - 5:10 pmCVG-FLO
10h 00m2 stops
$378American Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 8
American Airlines Logo
5:15 am - 9:48 amFLO-DTW
4h 33m1 stop
American Airlines Logo
6:00 am - 10:45 amDTW-FLO
4h 45m1 stop
$389American Airlines
Find Deal
Sun, Nov 23 - Mon, Dec 1
American Airlines Logo
11:11 am - 7:27 pmFLO-DTW
8h 16m2 stops
American Airlines Logo
5:22 pm - 11:41 pmDTW-FLO
6h 19m1 stop
$394American Airlines
Find Deal
Sun, Nov 23 - Mon, Dec 1
American Airlines Logo
6:15 am - 6:06 pmFLO-PIT
11h 51m2 stops
American Airlines Logo
8:04 am - 6:07 pmPIT-FLO
10h 03m2 stops
$428American Airlines
Find Deal
Wed, Nov 19 - Sun, Nov 23
American Airlines Logo
5:15 am - 8:30 amFLO-PIT
3h 15m1 stop
American Airlines Logo
5:43 pm - 12:15 amPIT-FLO
6h 32m1 stop
$475American Airlines
Find Deal
Thu, Dec 4 - Sat, Dec 6
American Airlines Logo
6:18 pm - 10:59 pmFLO-CAK
4h 41m1 stop
American Airlines Logo
11:51 am - 5:49 pmCAK-FLO
5h 58m1 stop
$475American Airlines
Find Deal
Sat, Feb 28 - Sat, Mar 7
American Airlines Logo
7:00 am - 11:13 amFLO-CVG
4h 13m1 stop
American Airlines Logo
5:04 pm - 10:53 pmCVG-FLO
5h 49m1 stop
$478American Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 8

American Airlines flights from Florence, South Carolina to Ohio

Our best American Airlines deals on Florence, South Carolina to Ohio flight tickets
American Airlines
Dec 4
FLO6:31 pmFlorence
5h 51m
1 stop
DTW12:22 amDetroit Metropolitan Wayne County
Dec 11
DTW12:00 pmDetroit Metropolitan Wayne County
6h 05m
1 stop
FLO6:05 pmFlorence
$303
Find similar
American Airlines
Dec 4
FLO5:15 amFlorence
8h 25m
2 stops
DTW1:40 pmDetroit Metropolitan Wayne County
Dec 11
DTW7:40 pmDetroit Metropolitan Wayne County
4h 23m
1 stop
FLO12:03 amFlorence
$308
Find similar
American Airlines
Dec 4
FLO11:16 amFlorence
8h 44m
2 stops
DTW8:00 pmDetroit Metropolitan Wayne County
Dec 11
DTW9:40 amDetroit Metropolitan Wayne County
8h 25m
2 stops
FLO6:05 pmFlorence
$313
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to Ohio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 12/4

6:31 pm-12:22 am

1 stop5h 51m

Detroit Metropolitan Wayne County

Thu 12/11

12:00 pm-6:05 pm

1 stop6h 05m

$303

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 12/4

5:15 am-1:40 pm

2 stops8h 25m

Detroit Metropolitan Wayne County

Thu 12/11

7:40 pm-12:03 am

1 stop4h 23m

$308

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 12/4

11:16 am-8:00 pm

2 stops8h 44m

Detroit Metropolitan Wayne County

Thu 12/11

9:40 am-6:05 pm

2 stops8h 25m

$313

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Thu 11/27

7:00 am-10:50 am

2 stops27h 50m

Cincinnati Cinci./N. Kentucky

Mon 12/8

7:10 am-5:10 pm

2 stops10h 00m

$378

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Sun 11/23

5:15 am-9:48 am

1 stop4h 33m

Detroit Metropolitan Wayne County

Mon 12/1

6:00 am-10:45 am

1 stop4h 45m

$389

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Sun 11/23

11:11 am-7:27 pm

2 stops8h 16m

Detroit Metropolitan Wayne County

Mon 12/1

5:22 pm-11:41 pm

1 stop6h 19m

$394

FlorencePittsburgh

FLO - PIT

FLOPIT

Florence

Wed 11/19

6:15 am-6:06 pm

2 stops11h 51m

Pittsburgh

Sun 11/23

8:04 am-6:07 pm

2 stops10h 03m

$428

FlorencePittsburgh

FLO - PIT

FLOPIT

Florence

Thu 12/4

5:15 am-8:30 am

1 stop3h 15m

Pittsburgh

Sat 12/6

5:43 pm-12:15 am

1 stop6h 32m

$475

FlorenceAkron

FLO - CAK

FLOCAK

Florence

Sat 2/28

6:18 pm-10:59 pm

1 stop4h 41m

Akron/Canton

Sat 3/7

11:51 am-5:49 pm

1 stop5h 58m

$475

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Thu 11/27

7:00 am-11:13 am

1 stop4h 13m

Cincinnati Cinci./N. Kentucky

Mon 12/8

5:04 pm-10:53 pm

1 stop5h 49m

$478

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Ohio from

How to get the cheapest flight ticket from Florence, South Carolina to Ohio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Ohio?

Our data shows that Tuesday is the least expensive day to fly to Ohio. Tickets to fly out on this day can be as low as $465. The most expensive day to fly to Ohio is Thursday, with ticket prices averaging around $490.

Can stopping save me money on Florence, South Carolina to Ohio flights?

You could potentially save up to 21% on your flight if you consider stops on a Florence, South Carolina to Ohio flight.

Cheap Florence, South Carolina to Ohio flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Ohio

Direct flights

None
There are no direct flights from Florence, South Carolina to Ohio. There are no popular flight routes from Florence, South Carolina to Ohio.
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  • When did momondo last update prices for flights from Florence Airport to Ohio?

    Prices for flights from Florence Airport to Ohio were last updated today.

  • How many operators does momondo search for flights from Florence Airport to Ohio?

  • How old do you have to be to fly from Florence Airport to Ohio?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport to Ohio.

  • What documentation or ID do you need to fly to Ohio?

    The travel and health documents required for your trip to Ohio can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Ohio. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Florence, South Carolina to Ohio

Compare and see reviews for airlines that fly from Florence, South Carolina to Ohio with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $380Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Ohio?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Florence to Ohio. momondo saves you time and could save you money on your trip.

Can I find flights from Florence to Ohio with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Ohio from Florence with this policy.

How can momondo help me find flights from Florence to Ohio?

momondo helps you find the best flight between Florence and Ohio by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florence to Ohio right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Ohio from Florence. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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