What airlines fly to Missouri?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Missouri from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 5 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Florence Airport to Missouri?

Prices for flights from Florence Airport to Missouri were last updated today.

How old do you have to be to fly from Florence Airport to Missouri?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florence Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$278 Cheap Flights from Florence to Missouri in 2026

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Find the cheapest flights from Florence, South Carolina to Missouri

Round-trip

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:16 am - 8:35 am

FLO

STL

4h 19m

1 stop

5:53 pm - 10:42 pm

STL

FLO

3h 49m

1 stop

$278American Airlines

Thu, Apr 2 - Tue, Apr 7

5:16 am - 8:35 am

FLO

STL

4h 19m

1 stop

12:27 pm - 10:42 pm

STL

FLO

9h 15m

2 stops

$283American Airlines

Thu, Apr 2 - Tue, Apr 7

5:16 am - 12:44 pm

FLO

STL

8h 28m

2 stops

6:27 am - 3:32 pm

STL

FLO

8h 05m

2 stops

$289American Airlines

Thu, Apr 2 - Tue, Apr 7

5:16 am - 8:35 am

FLO

STL

4h 19m

1 stop

5:51 pm - 11:08 pm

STL

FLO

4h 17m

1 stop

$349American Airlines

Fri, Mar 13 - Tue, Mar 17

5:16 am - 8:35 am

FLO

STL

4h 19m

1 stop

3:49 pm - 11:08 pm

STL

FLO

6h 19m

2 stops

$354American Airlines

Fri, Mar 13 - Tue, Mar 17

5:16 am - 2:56 pm

FLO

STL

10h 40m

2 stops

8:00 am - 5:21 pm

STL

FLO

8h 21m

2 stops

$359American Airlines

Fri, Mar 13 - Tue, Mar 17

5:58 pm - 10:26 pm

FLO

MCI

5h 28m

1 stop

10:24 am - 5:50 pm

MCI

FLO

6h 26m

1 stop

$501American Airlines

Tue, Mar 17 - Sat, Mar 21

6:15 am - 3:41 pm

FLO

MCI

10h 26m

2 stops

10:24 am - 5:50 pm

MCI

FLO

6h 26m

1 stop

$506American Airlines

Tue, Mar 17 - Sat, Mar 21

6:15 am - 3:41 pm

FLO

MCI

10h 26m

2 stops

6:40 am - 5:50 pm

MCI

FLO

10h 10m

2 stops

$540American Airlines

Tue, Mar 17 - Sat, Mar 21

American Airlines flights from Florence, South Carolina to Missouri

Our best American Airlines deals on Florence, South Carolina to Missouri flight tickets

American Airlines

Apr 2

FLO5:16 amFlorence

4h 19m

1 stop

STL8:35 amLambert-St Louis

Apr 7

STL5:53 pmLambert-St Louis

3h 49m

1 stop

FLO10:42 pmFlorence

$278

American Airlines

Apr 2

FLO5:16 amFlorence

4h 19m

1 stop

STL8:35 amLambert-St Louis

Apr 7

STL12:27 pmLambert-St Louis

9h 15m

2 stops

FLO10:42 pmFlorence

$283

American Airlines

Apr 2

FLO5:16 amFlorence

8h 28m

2 stops

STL12:44 pmLambert-St Louis

Apr 7

STL6:27 amLambert-St Louis

8h 05m

2 stops

FLO3:32 pmFlorence

$289

momondo Fare Finder

Use the filters below to find and compare flights from Florence, South Carolina to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Thu 4/2

5:16 am-8:35 am

1 stop4h 19m

Lambert-St Louis

Tue 4/7

5:53 pm-10:42 pm

1 stop3h 49m

$278

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Thu 4/2

5:16 am-8:35 am

1 stop4h 19m

Lambert-St Louis

Tue 4/7

12:27 pm-10:42 pm

2 stops9h 15m

$283

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Thu 4/2

5:16 am-12:44 pm

2 stops8h 28m

Lambert-St Louis

Tue 4/7

6:27 am-3:32 pm

2 stops8h 05m

$289

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 3/13

5:16 am-8:35 am

1 stop4h 19m

Lambert-St Louis

Tue 3/17

5:51 pm-11:08 pm

1 stop4h 17m

$349

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 3/13

5:16 am-8:35 am

1 stop4h 19m

Lambert-St Louis

Tue 3/17

3:49 pm-11:08 pm

2 stops6h 19m

$354

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 3/13

5:16 am-2:56 pm

2 stops10h 40m

Lambert-St Louis

Tue 3/17

8:00 am-5:21 pm

2 stops8h 21m

$359

FlorenceKansas City

FLO - MCI

FLOMCI

Florence

Tue 3/17

5:58 pm-10:26 pm

1 stop5h 28m

Kansas City

Sat 3/21

10:24 am-5:50 pm

1 stop6h 26m

$501

FlorenceKansas City

FLO - MCI

FLOMCI

Florence

Tue 3/17

6:15 am-3:41 pm

2 stops10h 26m

Kansas City

Sat 3/21

10:24 am-5:50 pm

1 stop6h 26m

$506

FlorenceKansas City

FLO - MCI

FLOMCI

Florence

Tue 3/17

6:15 am-3:41 pm

2 stops10h 26m

Kansas City

Sat 3/21

6:40 am-5:50 pm

2 stops10h 10m

$540

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Florence, South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Florence, South Carolina to Missouri flights?

You could potentially save up to 54% on your flight if you consider stops on a Florence, South Carolina to Missouri flight.

Cheap Florence, South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Missouri

Fastest flight time	4h 19m
Direct flights	None

The fastest flight from Florence, South Carolina to Missouri takes 4h 19m

There are no direct flights from Florence, South Carolina to Missouri. There are no popular flight routes from Florence, South Carolina to Missouri.

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When did momondo last update prices for flights from Florence Airport to Missouri?
Prices for flights from Florence Airport to Missouri were last updated today.
How old do you have to be to fly from Florence Airport to Missouri?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florence Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Missouri?

It is quick and easy to find Florence to Missouri flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Missouri that suits you.

Can I find flights from Florence to Missouri with flexible booking policies on momondo?

Flights from Florence to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Florence to Missouri?

Once you have performed a search for Florence to Missouri flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Florence to Missouri right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Florence to Missouri flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.