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Cheap flights from Detroit to Santa Fe from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santa Fe departing on 7/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:37 am - 9:38 am
DTW
-
SAF
6h 01m
1 stop
American Airlines Logo
6:55 am - 5:06 pm
SAF
-
DTW
8h 11m
1 stop
$324American Airlines
Sun, Jun 14 - Sat, Jun 20
American Airlines Logo
6:00 am - 9:53 am
DTW
-
SAF
5h 53m
1 stop
American Airlines Logo
6:45 am - 5:19 pm
SAF
-
DTW
8h 34m
1 stop
$334American Airlines
Wed, Sep 23 - Sat, Sep 26
American Airlines Logo
6:00 am - 9:53 am
DTW
-
SAF
5h 53m
1 stop
American Airlines Logo
2:33 pm - 10:54 pm
SAF
-
DTW
6h 21m
1 stop
$369American Airlines
Wed, Oct 7 - Wed, Oct 14
American Airlines Logo
6:00 am - 9:53 am
DTW
-
SAF
5h 53m
1 stop
American Airlines Logo
12:44 pm - 12:18 am
SAF
-
DTW
9h 34m
2 stops
$379American Airlines
Wed, Oct 7 - Wed, Oct 14
American Airlines Logo
4:10 pm - 9:59 pm
DTW
-
SAF
7h 49m
1 stop
American Airlines Logo
6:55 am - 4:59 pm
SAF
-
DTW
8h 04m
1 stop
$422American Airlines
Thu, Jun 25 - Sun, Jun 28
American Airlines Logo
10:35 am - 2:02 pm
DTW
-
SAF
5h 27m
1 stop
American Airlines Logo
1:58 pm - 10:57 pm
SAF
-
DTW
6h 59m
1 stop
$424American Airlines
Mon, Oct 5 - Sat, Oct 17
American Airlines Logo
5:37 am - 9:38 am
DTW
-
SAF
6h 01m
1 stop
American Airlines Logo
6:55 am - 2:17 pm
SAF
-
DTW
5h 22m
1 stop
$429American Airlines
Thu, Jun 4 - Sat, Jun 6
American Airlines Logo
10:35 am - 2:02 pm
DTW
-
SAF
5h 27m
1 stop
American Airlines Logo
12:44 pm - 10:12 pm
SAF
-
DTW
7h 28m
1 stop
$430American Airlines
Wed, Oct 7 - Wed, Oct 14
American Airlines Logo
6:00 am - 9:53 am
DTW
-
SAF
5h 53m
1 stop
American Airlines Logo
12:44 pm - 12:18 am
SAF
-
DTW
9h 34m
2 stops
$440American Airlines
Wed, Oct 7 - Wed, Oct 14
American Airlines Logo
6:00 am - 9:53 am
DTW
-
SAF
5h 53m
1 stop
American Airlines Logo
6:45 am - 5:19 pm
SAF
-
DTW
8h 34m
1 stop
$443American Airlines
Sat, Sep 19 - Sun, Sep 20

American Airlines flights from Detroit to Santa Fe

Our best American Airlines deals on Detroit to Santa Fe flight tickets
American Airlines
Jun 14
DTW5:37 amDetroit Metropolitan Wayne County
6h 01m
1 stop
SAF9:38 amSanta Fe
Jun 20
SAF6:55 amSanta Fe
8h 11m
1 stop
DTW5:06 pmDetroit Metropolitan Wayne County
$324
American Airlines
Sep 23
DTW6:00 amDetroit Metropolitan Wayne County
5h 53m
1 stop
SAF9:53 amSanta Fe
Sep 26
SAF6:45 amSanta Fe
8h 34m
1 stop
DTW5:19 pmDetroit Metropolitan Wayne County
$334
American Airlines
Oct 7
DTW6:00 amDetroit Metropolitan Wayne County
5h 53m
1 stop
SAF9:53 amSanta Fe
Oct 14
SAF2:33 pmSanta Fe
6h 21m
1 stop
DTW10:54 pmDetroit Metropolitan Wayne County
$369

United Airlines flights from Detroit to Santa Fe

Our best United Airlines deals on Detroit to Santa Fe flight tickets
United Airlines
May 28
DTW8:00 amDetroit Metropolitan Wayne County
6h 47m
1 stop
SAF12:47 pmSanta Fe
Jun 1
SAF3:19 pmSanta Fe
5h 24m
1 stop
DTW10:43 pmDetroit Metropolitan Wayne County
$457
United Airlines
May 28
DTW8:00 amDetroit Metropolitan Wayne County
6h 47m
1 stop
SAF12:47 pmSanta Fe
Jun 1
SAF1:22 pmSanta Fe
8h 35m
2 stops
DTW11:57 pmDetroit Metropolitan Wayne County
$467
United Airlines
May 19
DTW1:41 pmDetroit Metropolitan Wayne County
8h 47m
2 stops
SAF8:28 pmSanta Fe
May 23
SAF10:30 amSanta Fe
11h 27m
2 stops
DTW11:57 pmDetroit Metropolitan Wayne County
$629

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from Detroit to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sun 6/14

5:37 am-9:38 am

1 stop6h 01m

Santa Fe

Sat 6/20

6:55 am-5:06 pm

1 stop8h 11m

$324

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 9/23

6:00 am-9:53 am

1 stop5h 53m

Santa Fe

Sat 9/26

6:45 am-5:19 pm

1 stop8h 34m

$334

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 10/7

6:00 am-9:53 am

1 stop5h 53m

Santa Fe

Wed 10/14

2:33 pm-10:54 pm

1 stop6h 21m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 10/7

6:00 am-9:53 am

1 stop5h 53m

Santa Fe

Wed 10/14

12:44 pm-12:18 am

2 stops9h 34m

$379

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 6/25

4:10 pm-9:59 pm

1 stop7h 49m

Santa Fe

Sun 6/28

6:55 am-4:59 pm

1 stop8h 04m

$422

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 10/5

10:35 am-2:02 pm

1 stop5h 27m

Santa Fe

Sat 10/17

1:58 pm-10:57 pm

1 stop6h 59m

$424
Quickest round-trip

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 6/4

5:37 am-9:38 am

1 stop6h 01m

Santa Fe

Sat 6/6

6:55 am-2:17 pm

1 stop5h 22m

$429

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 10/7

10:35 am-2:02 pm

1 stop5h 27m

Santa Fe

Wed 10/14

12:44 pm-10:12 pm

1 stop7h 28m

$430

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 10/7

6:00 am-9:53 am

1 stop5h 53m

Santa Fe

Wed 10/14

12:44 pm-12:18 am

2 stops9h 34m

$440

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 9/19

6:00 am-9:53 am

1 stop5h 53m

Santa Fe

Sun 9/20

6:45 am-5:19 pm

1 stop8h 34m

$443

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Santa Fe?

What is the cheapest month to fly to Santa Fe?

The month of November is, on average, the cheapest month to fly to Santa Fe from Detroit, with most prices found around $264. If you’re not able to fly to Santa Fe in November, then July is your next best option. Flight prices from Detroit to Santa Fe during July average around $264.

When to book flights from Detroit to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santa Fe (DTT to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santa Fe

Fastest flight time

6h 05m

Direct flights

None
The fastest flight from Detroit to Santa Fe takes 6h 05m
There are no direct flights from Detroit to Santa Fe. There are no popular flight routes from Detroit to Santa Fe.
Search flight deals

Frequently asked questions about flying from Detroit to Santa Fe

  • How far is Detroit to Santa Fe by plane?

    There are 1305.9 mi between Detroit and Santa Fe. By plane, this route typically takes 6h 05m.

  • When did momondo last update prices for flights from Detroit to Santa Fe Airport?

    Prices for flights from Detroit to Santa Fe Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santa Fe Airport?

  • How old do you have to be to fly from Detroit to Santa Fe Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The required travel and health documents for your Santa Fe Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Fe Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santa Fe?

Best airlines flying from Detroit to Santa Fe

Compare and see reviews for airlines that fly from Detroit to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $309Free CancellationRating
7.1
11,664 reviews
Search American Airlines flights
United AirlinesPriceFrom $344Free CancellationRating
7.4
9,711 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Los Alamos
Santa Rosa

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Fe?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Fe from Detroit.

Can I find flights from Detroit to Santa Fe with flexible booking policies on momondo?

All flight searches from Detroit to Santa Fe on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Santa Fe?

Once you have performed a search for Detroit to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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