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Cheap flights from Detroit to Santa Fe from $244

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santa Fe departing on 3/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:04 am - 10:07 am
DTW
-
SAF
6h 03m
1 stop
American Airlines Logo
2:04 pm - 10:59 pm
SAF
-
DTW
6h 55m
1 stop
$284American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
9:43 am - 5:56 pm
DTW
-
SAF
10h 13m
2 stops
American Airlines Logo
6:15 am - 2:49 pm
SAF
-
DTW
6h 34m
1 stop
$294American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
6:04 am - 10:07 am
DTW
-
SAF
6h 03m
1 stop
American Airlines Logo
6:15 am - 2:49 pm
SAF
-
DTW
6h 34m
1 stop
$309American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
9:43 am - 5:56 pm
DTW
-
SAF
10h 13m
2 stops
American Airlines Logo
6:15 am - 2:49 pm
SAF
-
DTW
6h 34m
1 stop
$319American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
10:30 am - 2:04 pm
DTW
-
SAF
5h 34m
1 stop
American Airlines Logo
3:55 pm - 11:58 pm
SAF
-
DTW
6h 03m
1 stop
$334American Airlines
Mon, Mar 23 - Sat, Mar 28
American Airlines Logo
7:40 am - 12:24 pm
DTW
-
SAF
6h 44m
1 stop
American Airlines Logo
2:33 pm - 12:31 am
SAF
-
DTW
7h 58m
1 stop
$385American Airlines
Wed, Mar 11 - Tue, Mar 17
United Airlines Logo
3:29 pm - 9:13 pm
DTW
-
SAF
7h 44m
1 stop
United Airlines Logo
3:31 pm - 10:53 pm
SAF
-
DTW
5h 22m
1 stop
$389United Airlines
Tue, Apr 28 - Sat, May 2
American Airlines Logo
10:11 am - 6:12 pm
DTW
-
SAF
10h 01m
2 stops
American Airlines Logo
2:33 pm - 12:31 am
SAF
-
DTW
7h 58m
1 stop
$395American Airlines
Wed, Mar 11 - Tue, Mar 17
United Airlines Logo
3:29 pm - 9:13 pm
DTW
-
SAF
7h 44m
1 stop
United Airlines Logo
1:19 pm - 11:55 pm
SAF
-
DTW
8h 36m
2 stops
$399United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
11:00 am - 9:13 pm
DTW
-
SAF
12h 13m
2 stops
United Airlines Logo
1:19 pm - 11:55 pm
SAF
-
DTW
8h 36m
2 stops
$404United Airlines
Tue, Apr 28 - Sat, May 2

American Airlines flights from Detroit to Santa Fe

Our best American Airlines deals on Detroit to Santa Fe flight tickets
American Airlines
Apr 29
DTW9:43 amDetroit Metropolitan Wayne County
10h 13m
2 stops
SAF5:56 pmSanta Fe
May 2
SAF6:15 amSanta Fe
6h 34m
1 stop
DTW2:49 pmDetroit Metropolitan Wayne County
$294
American Airlines
Apr 29
DTW6:04 amDetroit Metropolitan Wayne County
6h 03m
1 stop
SAF10:07 amSanta Fe
May 2
SAF6:15 amSanta Fe
6h 34m
1 stop
DTW2:49 pmDetroit Metropolitan Wayne County
$309
American Airlines
Apr 29
DTW9:43 amDetroit Metropolitan Wayne County
10h 13m
2 stops
SAF5:56 pmSanta Fe
May 2
SAF6:15 amSanta Fe
6h 34m
1 stop
DTW2:49 pmDetroit Metropolitan Wayne County
$319

United Airlines flights from Detroit to Santa Fe

Our best United Airlines deals on Detroit to Santa Fe flight tickets
United Airlines
Apr 28
DTW3:29 pmDetroit Metropolitan Wayne County
7h 44m
1 stop
SAF9:13 pmSanta Fe
May 2
SAF3:31 pmSanta Fe
5h 22m
1 stop
DTW10:53 pmDetroit Metropolitan Wayne County
$389
United Airlines
Apr 28
DTW3:29 pmDetroit Metropolitan Wayne County
7h 44m
1 stop
SAF9:13 pmSanta Fe
May 2
SAF1:19 pmSanta Fe
8h 36m
2 stops
DTW11:55 pmDetroit Metropolitan Wayne County
$399
United Airlines
Apr 28
DTW11:00 amDetroit Metropolitan Wayne County
12h 13m
2 stops
SAF9:13 pmSanta Fe
May 2
SAF1:19 pmSanta Fe
8h 36m
2 stops
DTW11:55 pmDetroit Metropolitan Wayne County
$404

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Detroit to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

6:04 am-10:07 am

1 stop6h 03m

Santa Fe

Sat 5/2

2:04 pm-10:59 pm

1 stop6h 55m

$284

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

9:43 am-5:56 pm

2 stops10h 13m

Santa Fe

Sat 5/2

6:15 am-2:49 pm

1 stop6h 34m

$294

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

6:04 am-10:07 am

1 stop6h 03m

Santa Fe

Sat 5/2

6:15 am-2:49 pm

1 stop6h 34m

$309

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

9:43 am-5:56 pm

2 stops10h 13m

Santa Fe

Sat 5/2

6:15 am-2:49 pm

1 stop6h 34m

$319

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 3/23

10:30 am-2:04 pm

1 stop5h 34m

Santa Fe

Sat 3/28

3:55 pm-11:58 pm

1 stop6h 03m

$334

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 3/11

7:40 am-12:24 pm

1 stop6h 44m

Santa Fe

Tue 3/17

2:33 pm-12:31 am

1 stop7h 58m

$385

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 4/28

3:29 pm-9:13 pm

1 stop7h 44m

Santa Fe

Sat 5/2

3:31 pm-10:53 pm

1 stop5h 22m

$389

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 3/11

10:11 am-6:12 pm

2 stops10h 01m

Santa Fe

Tue 3/17

2:33 pm-12:31 am

1 stop7h 58m

$395

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 4/28

3:29 pm-9:13 pm

1 stop7h 44m

Santa Fe

Sat 5/2

1:19 pm-11:55 pm

2 stops8h 36m

$399

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 4/28

11:00 am-9:13 pm

2 stops12h 13m

Santa Fe

Sat 5/2

1:19 pm-11:55 pm

2 stops8h 36m

$404

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from Detroit to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Detroit to Santa Fe?

United Airlines and American Airlines are the most popular carriers operating from Detroit to Santa Fe

What airlines fly to Santa Fe?

American Airlines, Southwest and United Airlines are the top three most popular airlines that fly to Santa Fe from Detroit according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Santa Fe. Keep in mind that there are 4 different airlines that fly to Santa Fe on a routine basis, so you have a few additional options to choose from.

When to book flights from Detroit to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santa Fe (DTT to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santa Fe

Fastest flight time

5h 47m

Direct flights

None
The fastest flight from Detroit to Santa Fe takes 5h 47m
There are no direct flights from Detroit to Santa Fe. There are no popular flight routes from Detroit to Santa Fe.
Search flight deals

  • How far is Detroit to Santa Fe by plane?

    There are 1305.9 mi between Detroit and Santa Fe. By plane, this route typically takes 5h 47m.

  • When did momondo last update prices for flights from Detroit to Santa Fe Airport?

    Prices for flights from Detroit to Santa Fe Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santa Fe Airport?

  • How old do you have to be to fly from Detroit to Santa Fe Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The required travel and health documents for your Santa Fe Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Fe Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santa Fe?

Best airlines flying from Detroit to Santa Fe

Compare and see reviews for airlines that fly from Detroit to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $309Free CancellationRating
7.2
11,258 reviews
Search American Airlines flights
United AirlinesPriceFrom $344Free CancellationRating
7.4
9,262 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Fe?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Fe from Detroit.

Can I find flights from Detroit to Santa Fe with flexible booking policies on momondo?

All flight searches from Detroit to Santa Fe on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Santa Fe?

Once you have performed a search for Detroit to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Santa Fe trip

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