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Cheap flights from Detroit to Santa Fe from $234

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santa Fe departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit to Santa Fe

Cheap round-trip flights

American Airlines Logo
5:11 am - 9:28 amDTW-SAF
6h 17m1 stop
American Airlines Logo
6:15 am - 3:00 pmSAF-DTW
6h 45m1 stop
$264American Airlines
Find Deal
Fri, Nov 14 - Tue, Nov 18
United Airlines Logo
4:53 pm - 10:00 pmDTW-SAF
7h 07m1 stop
United Airlines Logo
10:45 am - 11:59 pmSAF-DTW
11h 14m2 stops
$299United Airlines
Find Deal
Sat, Sep 20 - Wed, Sep 24
American Airlines Logo
5:11 am - 9:28 amDTW-SAF
6h 17m1 stop
American Airlines Logo
6:15 am - 3:00 pmSAF-DTW
6h 45m1 stop
$314American Airlines
Find Deal
Fri, Nov 7 - Tue, Nov 11
American Airlines Logo
5:42 pm - 9:59 pmDTW-SAF
6h 17m1 stop
American Airlines Logo
7:15 am - 4:45 pmSAF-DTW
7h 30m1 stop
$319American Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
United Airlines Logo
6:00 am - 5:09 pmDTW-SAF
13h 09m2 stops
United Airlines Logo
1:25 pm - 10:17 pmSAF-DTW
6h 52m1 stop
$326United Airlines
Find Deal
Mon, Sep 22 - Tue, Oct 28
United Airlines Logo
6:00 am - 5:09 pmDTW-SAF
13h 09m2 stops
United Airlines Logo
1:25 pm - 11:35 pmSAF-DTW
8h 10m2 stops
$335United Airlines
Find Deal
Mon, Sep 22 - Tue, Oct 28
American Airlines Logo
5:02 am - 9:31 amDTW-SAF
6h 29m1 stop
American Airlines Logo
8:09 am - 3:56 pmSAF-DTW
5h 47m1 stop
$344American Airlines
Find Deal
Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
5:02 am - 3:47 pmDTW-SAF
12h 45m2 stops
American Airlines Logo
4:50 pm - 12:15 amSAF-DTW
5h 25m1 stop
$354American Airlines
Find Deal
Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
7:15 am - 5:38 pmDTW-SAF
12h 23m2 stops
American Airlines Logo
7:08 pm - 10:29 amSAF-DTW
13h 21m2 stops
$359American Airlines
Find Deal
Sat, Dec 6 - Wed, Dec 10
United Airlines Logo
11:00 am - 10:00 pmDTW-SAF
13h 00m3 stops
United Airlines Logo
7:00 am - 6:50 pmSAF-DTW
9h 50m2 stops
$364United Airlines
Find Deal
Tue, Sep 16 - Tue, Sep 23

American Airlines flights from Detroit to Santa Fe

Our best American Airlines deals on Detroit to Santa Fe flight tickets
American Airlines
Nov 14
DTW5:11 amDetroit Metropolitan Wayne County
6h 17m
1 stop
SAF9:28 amSanta Fe
Nov 18
SAF6:15 amSanta Fe
6h 45m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
$264
Find similar
American Airlines
Nov 7
DTW5:11 amDetroit Metropolitan Wayne County
6h 17m
1 stop
SAF9:28 amSanta Fe
Nov 11
SAF6:15 amSanta Fe
6h 45m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
$314
Find similar
American Airlines
Oct 20
DTW5:42 pmDetroit Metropolitan Wayne County
6h 17m
1 stop
SAF9:59 pmSanta Fe
Oct 28
SAF7:15 amSanta Fe
7h 30m
1 stop
DTW4:45 pmDetroit Metropolitan Wayne County
$319
Find similar

United Airlines flights from Detroit to Santa Fe

Our best United Airlines deals on Detroit to Santa Fe flight tickets
United Airlines
Sep 20
DTW4:53 pmDetroit Metropolitan Wayne County
7h 07m
1 stop
SAF10:00 pmSanta Fe
Sep 24
SAF10:45 amSanta Fe
11h 14m
2 stops
DTW11:59 pmDetroit Metropolitan Wayne County
$299
Find similar
United Airlines
Sep 22
DTW6:00 amDetroit Metropolitan Wayne County
13h 09m
2 stops
SAF5:09 pmSanta Fe
Oct 28
SAF1:25 pmSanta Fe
6h 52m
1 stop
DTW10:17 pmDetroit Metropolitan Wayne County
$326
Find similar
United Airlines
Sep 22
DTW6:00 amDetroit Metropolitan Wayne County
13h 09m
2 stops
SAF5:09 pmSanta Fe
Oct 28
SAF1:25 pmSanta Fe
8h 10m
2 stops
DTW11:35 pmDetroit Metropolitan Wayne County
$335
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Detroit to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/14

5:11 am-9:28 am

1 stop6h 17m

Santa Fe

Tue 11/18

6:15 am-3:00 pm

1 stop6h 45m

$264

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 9/20

4:53 pm-10:00 pm

1 stop7h 07m

Santa Fe

Wed 9/24

10:45 am-11:59 pm

2 stops11h 14m

$299

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/7

5:11 am-9:28 am

1 stop6h 17m

Santa Fe

Tue 11/11

6:15 am-3:00 pm

1 stop6h 45m

$314

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 10/20

5:42 pm-9:59 pm

1 stop6h 17m

Santa Fe

Tue 10/28

7:15 am-4:45 pm

1 stop7h 30m

$319

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 9/22

6:00 am-5:09 pm

2 stops13h 09m

Santa Fe

Tue 10/28

1:25 pm-10:17 pm

1 stop6h 52m

$326

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 9/22

6:00 am-5:09 pm

2 stops13h 09m

Santa Fe

Tue 10/28

1:25 pm-11:35 pm

2 stops8h 10m

$335

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 12/6

5:02 am-9:31 am

1 stop6h 29m

Santa Fe

Wed 12/10

8:09 am-3:56 pm

1 stop5h 47m

$344

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 12/6

5:02 am-3:47 pm

2 stops12h 45m

Santa Fe

Wed 12/10

4:50 pm-12:15 am

1 stop5h 25m

$354

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 12/6

7:15 am-5:38 pm

2 stops12h 23m

Santa Fe

Wed 12/10

7:08 pm-10:29 am

2 stops13h 21m

$359

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 9/16

11:00 am-10:00 pm

3 stops13h 00m

Santa Fe

Tue 9/23

7:00 am-6:50 pm

2 stops9h 50m

$364

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from Detroit to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Fe?

According to our data, Wednesday is the cheapest day to fly to Santa Fe from Detroit. The lowest ticket price found for a Wednesday departure recently was $479. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santa Fe on Sunday is $674.

What is the cheapest time of day to depart on your flight to Santa Fe?

The cheapest time of day to fly to Santa Fe is in the afternoon when flights can be purchased for as low as $516. Try not to purchase tickets in the morning because they tend to be around $541. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Detroit to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santa Fe (DTT to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santa Fe

Direct flights

None
There are no direct flights from Detroit to Santa Fe. There are no popular flight routes from Detroit to Santa Fe.
Search flight deals

  • How far is Detroit to Santa Fe by plane?

    There are 1305.9 mi between Detroit and Santa Fe. By plane, this route typically takes 5h 49m.

  • When did momondo last update prices for flights from Detroit to Santa Fe Airport?

    Prices for flights from Detroit to Santa Fe Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santa Fe Airport?

  • How old do you have to be to fly from Detroit to Santa Fe Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The required travel and health documents for your Santa Fe Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Fe Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santa Fe?

Best airlines flying from Detroit to Santa Fe

Compare and see reviews for airlines that fly from Detroit to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $380Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $462Free CancellationRating
7.4
8,930 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Fe?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Fe from Detroit.

Can I find flights from Detroit to Santa Fe with flexible booking policies on momondo?

All flight searches from Detroit to Santa Fe on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Santa Fe?

Once you have performed a search for Detroit to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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