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Cheap flights from Detroit to Santa Fe from $264

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santa Fe departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 2:53 pm
DTW
-
SAF
10h 53m2 stops
American Airlines Logo
12:59 pm - 10:35 pm
SAF
-
DTW
7h 36m1 stop
$294American Airlines
Wed, Jan 14 - Wed, Jan 21
United Airlines Logo
9:00 am - 12:39 pm
DTW
-
SAF
5h 39m1 stop
United Airlines Logo
7:00 am - 3:08 pm
SAF
-
DTW
6h 08m1 stop
$364United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
9:00 am - 4:56 pm
DTW
-
SAF
9h 56m2 stops
United Airlines Logo
1:16 pm - 10:30 pm
SAF
-
DTW
7h 14m1 stop
$374United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
11:05 am - 4:56 pm
DTW
-
SAF
7h 51m2 stops
United Airlines Logo
10:45 am - 11:37 pm
SAF
-
DTW
10h 52m2 stops
$379United Airlines
Sat, Jan 31 - Tue, Feb 3
American Airlines Logo
7:00 am - 12:29 pm
DTW
-
SAF
7h 29m1 stop
American Airlines Logo
12:59 pm - 10:35 pm
SAF
-
DTW
7h 36m1 stop
$385American Airlines
Wed, Jan 14 - Wed, Jan 21
United Airlines Logo
5:45 am - 5:02 pm
DTW
-
SAF
13h 17m2 stops
United Airlines Logo
1:16 pm - 10:30 pm
SAF
-
DTW
7h 14m1 stop
$424United Airlines
Fri, Jan 2 - Tue, Jan 6
United Airlines Logo
5:45 am - 5:02 pm
DTW
-
SAF
13h 17m2 stops
United Airlines Logo
10:45 am - 10:10 pm
SAF
-
DTW
9h 25m2 stops
$429United Airlines
Fri, Jan 2 - Tue, Jan 6
United Airlines Logo
9:00 am - 5:10 pm
DTW
-
SAF
10h 10m2 stops
United Airlines Logo
3:20 pm - 10:25 pm
SAF
-
DTW
5h 05m1 stop
$434United Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
7:06 am - 3:02 pm
DTW
-
SAF
9h 56m1 stop
American Airlines Logo
6:15 am - 3:09 pm
SAF
-
DTW
6h 54m1 stop
$438American Airlines
Thu, Mar 5 - Thu, Mar 12
United Airlines Logo
10:28 am - 5:10 pm
DTW
-
SAF
8h 42m2 stops
United Airlines Logo
1:24 pm - 11:57 pm
SAF
-
DTW
8h 33m2 stops
$439United Airlines
Wed, Mar 11 - Tue, Mar 17

American Airlines flights from Detroit to Santa Fe

Our best American Airlines deals on Detroit to Santa Fe flight tickets
American Airlines
Jan 14
DTW6:00 amDetroit Metropolitan Wayne County
10h 53m
2 stops
SAF2:53 pmSanta Fe
Jan 21
SAF12:59 pmSanta Fe
7h 36m
1 stop
DTW10:35 pmDetroit Metropolitan Wayne County
$294
Find similar
American Airlines
Jan 14
DTW7:00 amDetroit Metropolitan Wayne County
7h 29m
1 stop
SAF12:29 pmSanta Fe
Jan 21
SAF12:59 pmSanta Fe
7h 36m
1 stop
DTW10:35 pmDetroit Metropolitan Wayne County
$385
Find similar
American Airlines
Mar 5
DTW7:06 amDetroit Metropolitan Wayne County
9h 56m
1 stop
SAF3:02 pmSanta Fe
Mar 12
SAF6:15 amSanta Fe
6h 54m
1 stop
DTW3:09 pmDetroit Metropolitan Wayne County
$438
Find similar

United Airlines flights from Detroit to Santa Fe

Our best United Airlines deals on Detroit to Santa Fe flight tickets
United Airlines
Jan 31
DTW9:00 amDetroit Metropolitan Wayne County
5h 39m
1 stop
SAF12:39 pmSanta Fe
Feb 3
SAF7:00 amSanta Fe
6h 08m
1 stop
DTW3:08 pmDetroit Metropolitan Wayne County
$364
Find similar
United Airlines
Jan 31
DTW9:00 amDetroit Metropolitan Wayne County
9h 56m
2 stops
SAF4:56 pmSanta Fe
Feb 3
SAF1:16 pmSanta Fe
7h 14m
1 stop
DTW10:30 pmDetroit Metropolitan Wayne County
$374
Find similar
United Airlines
Jan 31
DTW11:05 amDetroit Metropolitan Wayne County
7h 51m
2 stops
SAF4:56 pmSanta Fe
Feb 3
SAF10:45 amSanta Fe
10h 52m
2 stops
DTW11:37 pmDetroit Metropolitan Wayne County
$379
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Detroit to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 1/14

6:00 am-2:53 pm

2 stops10h 53m

Santa Fe

Wed 1/21

12:59 pm-10:35 pm

1 stop7h 36m

$294

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 1/31

9:00 am-12:39 pm

1 stop5h 39m

Santa Fe

Tue 2/3

7:00 am-3:08 pm

1 stop6h 08m

$364

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 1/31

9:00 am-4:56 pm

2 stops9h 56m

Santa Fe

Tue 2/3

1:16 pm-10:30 pm

1 stop7h 14m

$374

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 1/31

11:05 am-4:56 pm

2 stops7h 51m

Santa Fe

Tue 2/3

10:45 am-11:37 pm

2 stops10h 52m

$379

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 1/14

7:00 am-12:29 pm

1 stop7h 29m

Santa Fe

Wed 1/21

12:59 pm-10:35 pm

1 stop7h 36m

$385

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 1/2

5:45 am-5:02 pm

2 stops13h 17m

Santa Fe

Tue 1/6

1:16 pm-10:30 pm

1 stop7h 14m

$424

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 1/2

5:45 am-5:02 pm

2 stops13h 17m

Santa Fe

Tue 1/6

10:45 am-10:10 pm

2 stops9h 25m

$429

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 3/11

9:00 am-5:10 pm

2 stops10h 10m

Santa Fe

Wed 3/18

3:20 pm-10:25 pm

1 stop5h 05m

$434

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 3/5

7:06 am-3:02 pm

1 stop9h 56m

Santa Fe

Thu 3/12

6:15 am-3:09 pm

1 stop6h 54m

$438

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 3/11

10:28 am-5:10 pm

2 stops8h 42m

Santa Fe

Tue 3/17

1:24 pm-11:57 pm

2 stops8h 33m

$439

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from Detroit to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Fe?

The month of July is, on average, the cheapest month to fly to Santa Fe from Detroit, with most prices found around $316. If you’re not able to fly to Santa Fe in July, then November is your next best option. Flight prices from Detroit to Santa Fe during November average around $344.

What is the cheapest day to depart on your flight to Santa Fe?

According to our data, Wednesday is the cheapest day to fly to Santa Fe from Detroit. The lowest ticket price found for a Wednesday departure recently was $479. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santa Fe on Sunday is $674.

What is the cheapest time of day to depart on your flight to Santa Fe?

The cheapest time of day to fly to Santa Fe is in the afternoon when flights can be purchased for as low as $516. Try not to purchase tickets in the morning because they tend to be around $541. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Detroit to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santa Fe (DTT to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santa Fe

Fastest flight time

5h 47m

Direct flights

None
The fastest flight from Detroit to Santa Fe takes 5h 47m
There are no direct flights from Detroit to Santa Fe. There are no popular flight routes from Detroit to Santa Fe.
Search flight deals

  • How far is Detroit to Santa Fe by plane?

    There are 1305.9 mi between Detroit and Santa Fe. By plane, this route typically takes 5h 47m.

  • When did momondo last update prices for flights from Detroit to Santa Fe Airport?

    Prices for flights from Detroit to Santa Fe Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santa Fe Airport?

  • How old do you have to be to fly from Detroit to Santa Fe Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The required travel and health documents for your Santa Fe Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Fe Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santa Fe?

Best airlines flying from Detroit to Santa Fe

Compare and see reviews for airlines that fly from Detroit to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $344Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $349Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Fe?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Fe from Detroit.

Can I find flights from Detroit to Santa Fe with flexible booking policies on momondo?

All flight searches from Detroit to Santa Fe on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Santa Fe?

Once you have performed a search for Detroit to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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