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Cheap flights from Detroit to Santa Fe from $274

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santa Fe departing on 6/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Detroit to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:42 pm - 9:07 pm
DTW
-
SAF
7h 25m
1 stop
American Airlines Logo
2:04 pm - 10:59 pm
SAF
-
DTW
6h 55m
1 stop
$344American Airlines
Sat, Apr 25 - Wed, Apr 29
United Airlines Logo
10:53 am - 8:38 pm
DTW
-
SAF
11h 45m
2 stops
United Airlines Logo
7:00 am - 2:33 pm
SAF
-
DTW
5h 33m
1 stop
$350United Airlines
Sat, Apr 18 - Sat, Apr 25
American Airlines Logo
9:43 am - 5:56 pm
DTW
-
SAF
10h 13m
2 stops
American Airlines Logo
2:04 pm - 10:59 pm
SAF
-
DTW
6h 55m
1 stop
$354American Airlines
Sat, Apr 25 - Wed, Apr 29
United Airlines Logo
8:00 am - 12:47 pm
DTW
-
SAF
6h 47m
1 stop
United Airlines Logo
1:22 pm - 11:43 pm
SAF
-
DTW
8h 21m
2 stops
$429United Airlines
Tue, Jun 2 - Sat, Jun 6
United Airlines Logo
3:29 pm - 9:13 pm
DTW
-
SAF
7h 44m
1 stop
United Airlines Logo
7:00 am - 2:31 pm
SAF
-
DTW
5h 31m
1 stop
$434United Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
5:36 am - 9:38 am
DTW
-
SAF
6h 02m
1 stop
American Airlines Logo
6:05 am - 3:14 pm
SAF
-
DTW
7h 09m
1 stop
$435American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
4:10 pm - 9:52 pm
DTW
-
SAF
7h 42m
1 stop
American Airlines Logo
6:45 am - 2:15 pm
SAF
-
DTW
5h 30m
1 stop
$443American Airlines
Tue, Jun 2 - Sat, Jun 6
United Airlines Logo
11:00 am - 9:13 pm
DTW
-
SAF
12h 13m
2 stops
United Airlines Logo
3:31 pm - 10:53 pm
SAF
-
DTW
5h 22m
1 stop
$444United Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
6:00 am - 2:55 pm
DTW
-
SAF
10h 55m
2 stops
American Airlines Logo
6:15 am - 2:49 pm
SAF
-
DTW
6h 34m
1 stop
$445American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
11:43 am - 6:51 pm
DTW
-
SAF
9h 08m
2 stops
American Airlines Logo
6:45 am - 2:40 pm
SAF
-
DTW
5h 55m
1 stop
$453American Airlines
Fri, Aug 21 - Wed, Aug 26

United Airlines flights from Detroit to Santa Fe

Our best United Airlines deals on Detroit to Santa Fe flight tickets
United Airlines
Apr 18
DTW10:53 amDetroit Metropolitan Wayne County
11h 45m
2 stops
SAF8:38 pmSanta Fe
Apr 25
SAF7:00 amSanta Fe
5h 33m
1 stop
DTW2:33 pmDetroit Metropolitan Wayne County
$350
United Airlines
Jun 2
DTW8:00 amDetroit Metropolitan Wayne County
6h 47m
1 stop
SAF12:47 pmSanta Fe
Jun 6
SAF1:22 pmSanta Fe
8h 21m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
$429
United Airlines
Apr 29
DTW3:29 pmDetroit Metropolitan Wayne County
7h 44m
1 stop
SAF9:13 pmSanta Fe
May 2
SAF7:00 amSanta Fe
5h 31m
1 stop
DTW2:31 pmDetroit Metropolitan Wayne County
$434

American Airlines flights from Detroit to Santa Fe

Our best American Airlines deals on Detroit to Santa Fe flight tickets
American Airlines
Apr 25
DTW3:42 pmDetroit Metropolitan Wayne County
7h 25m
1 stop
SAF9:07 pmSanta Fe
Apr 29
SAF2:04 pmSanta Fe
6h 55m
1 stop
DTW10:59 pmDetroit Metropolitan Wayne County
$344
American Airlines
Apr 25
DTW9:43 amDetroit Metropolitan Wayne County
10h 13m
2 stops
SAF5:56 pmSanta Fe
Apr 29
SAF2:04 pmSanta Fe
6h 55m
1 stop
DTW10:59 pmDetroit Metropolitan Wayne County
$354
American Airlines
May 27
DTW5:36 amDetroit Metropolitan Wayne County
6h 02m
1 stop
SAF9:38 amSanta Fe
Jun 3
SAF6:05 amSanta Fe
7h 09m
1 stop
DTW3:14 pmDetroit Metropolitan Wayne County
$435

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Detroit to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 4/25

3:42 pm-9:07 pm

1 stop7h 25m

Santa Fe

Wed 4/29

2:04 pm-10:59 pm

1 stop6h 55m

$344

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 4/18

10:53 am-8:38 pm

2 stops11h 45m

Santa Fe

Sat 4/25

7:00 am-2:33 pm

1 stop5h 33m

$350

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 4/25

9:43 am-5:56 pm

2 stops10h 13m

Santa Fe

Wed 4/29

2:04 pm-10:59 pm

1 stop6h 55m

$354

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 6/2

8:00 am-12:47 pm

1 stop6h 47m

Santa Fe

Sat 6/6

1:22 pm-11:43 pm

2 stops8h 21m

$429

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

3:29 pm-9:13 pm

1 stop7h 44m

Santa Fe

Sat 5/2

7:00 am-2:31 pm

1 stop5h 31m

$434
Quickest round-trip

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 5/27

5:36 am-9:38 am

1 stop6h 02m

Santa Fe

Wed 6/3

6:05 am-3:14 pm

1 stop7h 09m

$435

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 6/2

4:10 pm-9:52 pm

1 stop7h 42m

Santa Fe

Sat 6/6

6:45 am-2:15 pm

1 stop5h 30m

$443

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

11:00 am-9:13 pm

2 stops12h 13m

Santa Fe

Sat 5/2

3:31 pm-10:53 pm

1 stop5h 22m

$444

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 4/29

6:00 am-2:55 pm

2 stops10h 55m

Santa Fe

Sat 5/2

6:15 am-2:49 pm

1 stop6h 34m

$445

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 8/21

11:43 am-6:51 pm

2 stops9h 08m

Santa Fe

Wed 8/26

6:45 am-2:40 pm

1 stop5h 55m

$453

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from Detroit to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Fe?

The month of July is, on average, the cheapest month to fly to Santa Fe from Detroit, with most prices found around $316. If you’re not able to fly to Santa Fe in July, then November is your next best option. Flight prices from Detroit to Santa Fe during November average around $344.

When to book flights from Detroit to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santa Fe (DTT to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santa Fe

Fastest flight time

6h 47m

Direct flights

None
The fastest flight from Detroit to Santa Fe takes 6h 47m
There are no direct flights from Detroit to Santa Fe. There are no popular flight routes from Detroit to Santa Fe.
Search flight deals

  • How far is Detroit to Santa Fe by plane?

    There are 1305.9 mi between Detroit and Santa Fe. By plane, this route typically takes 6h 47m.

  • When did momondo last update prices for flights from Detroit to Santa Fe Airport?

    Prices for flights from Detroit to Santa Fe Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santa Fe Airport?

  • How old do you have to be to fly from Detroit to Santa Fe Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The required travel and health documents for your Santa Fe Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Fe Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santa Fe?

Best airlines flying from Detroit to Santa Fe

Compare and see reviews for airlines that fly from Detroit to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $284Free CancellationRating
7.1
11,495 reviews
Search American Airlines flights
United AirlinesPriceFrom $344Free CancellationRating
7.4
9,483 reviews
Search United Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Los Alamos
Santa Rosa

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Fe?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Fe from Detroit.

Can I find flights from Detroit to Santa Fe with flexible booking policies on momondo?

All flight searches from Detroit to Santa Fe on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Santa Fe?

Once you have performed a search for Detroit to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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