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Cheap flights from Detroit to Knoxville from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Knoxville departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Knoxville (DTT-TYS)

Cheap round-trip flights

Frontier Logo
11:49 am - 7:50 pmDTW-TYS
8h 01m1 stop
Frontier Logo
5:08 pm - 12:46 amTYS-DTW
7h 38m1 stop
$197Frontier
Find Deal
Thu, Sep 4 - Sun, Sep 7
Logo
6:30 pm - 9:07 pmDTW-TYS
26h 37m1 stop
Logo
8:32 pm - 8:15 amTYS-DTW
11h 43m1 stop
$210
Find Deal
Thu, Sep 11 - Mon, Sep 15
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
Logo
4:31 pm - 11:43 pmTYS-DTW
7h 12m1 stop
$212
Find Deal
Mon, Sep 15 - Wed, Sep 17
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
Logo
1:22 pm - 8:40 amTYS-DTW
19h 18m1 stop
$221
Find Deal
Mon, Sep 15 - Mon, Sep 22
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
Logo
4:31 pm - 8:14 amTYS-DTW
15h 43m2 stops
$223
Find Deal
Mon, Sep 15 - Wed, Sep 17
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
Logo
1:22 pm - 10:40 pmTYS-DTW
9h 18m1 stop
$225
Find Deal
Mon, Sep 8 - Fri, Sep 12
Logo
7:10 am - 8:59 pmDTW-TYS
13h 49m1 stop
Logo
4:00 pm - 8:15 amTYS-DTW
16h 15m1 stop
$226
Find Deal
Mon, Sep 22 - Wed, Sep 24
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
Logo
1:22 pm - 8:40 amTYS-DTW
19h 18m1 stop
$228
Find Deal
Mon, Sep 15 - Mon, Sep 22
Logo
8:49 pm - 2:29 pmDTW-TYS
17h 40m1 stop
Logo
7:30 am - 7:57 amTYS-DTW
24h 27m1 stop
$231
Find Deal
Sat, Sep 6 - Tue, Sep 9
Frontier Logo
11:49 am - 7:50 pmDTW-TYS
8h 01m1 stop
Frontier Logo
5:08 pm - 12:46 amTYS-DTW
7h 38m1 stop
$239Frontier
Find Deal
Thu, Sep 4 - Sun, Sep 7

United Airlines flights from Detroit to Knoxville

Our best United Airlines deals on Detroit to Knoxville flight tickets
United Airlines
Sep 4
DTW9:47 amDetroit Metropolitan Wayne County
11h 09m
2 stops
TYS8:56 pmKnoxville McGhee Tyson
Sep 8
TYS5:35 pmKnoxville McGhee Tyson
19h 39m
1 stop
DTW1:14 pmDetroit Metropolitan Wayne County
$428
Find similar
United Airlines
Aug 23
DTW6:00 amDetroit Metropolitan Wayne County
4h 28m
1 stop
TYS10:28 amKnoxville McGhee Tyson
Aug 30
TYS7:25 pmKnoxville McGhee Tyson
4h 34m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$519
Find similar
United Airlines
Aug 23
DTW6:00 amDetroit Metropolitan Wayne County
7h 25m
2 stops
TYS1:25 pmKnoxville McGhee Tyson
Aug 30
TYS10:54 amKnoxville McGhee Tyson
5h 52m
1 stop
DTW4:46 pmDetroit Metropolitan Wayne County
$524
Find similar

Delta flights from Detroit to Knoxville

Our best Delta deals on Detroit to Knoxville flight tickets
Delta
Sep 4
DTW10:00 amDetroit Metropolitan Wayne County
1h 34m
TYS11:34 amKnoxville McGhee Tyson
Sep 8
TYS6:14 pmKnoxville McGhee Tyson
6h 15m
1 stop
DTW12:29 amDetroit Metropolitan Wayne County
$409
Find similar
Delta
Aug 28
DTW10:00 amDetroit Metropolitan Wayne County
1h 34m
TYS11:34 amKnoxville McGhee Tyson
Sep 4
TYS1:00 pmKnoxville McGhee Tyson
1h 43m
DTW2:43 pmDetroit Metropolitan Wayne County
$429
Find similar
Delta
Aug 28
DTW10:00 amDetroit Metropolitan Wayne County
1h 34m
TYS11:34 amKnoxville McGhee Tyson
Sep 4
TYS4:19 pmKnoxville McGhee Tyson
5h 41m
1 stop
DTW10:00 pmDetroit Metropolitan Wayne County
$439
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Detroit to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 9/4

11:49 am-7:50 pm

1 stop8h 01m

Knoxville McGhee Tyson

Sun 9/7

5:08 pm-12:46 am

1 stop7h 38m

$197

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 9/11

6:30 pm-9:07 pm

1 stop26h 37m

Knoxville McGhee Tyson

Mon 9/15

8:32 pm-8:15 am

1 stop11h 43m

$210

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

Knoxville McGhee Tyson

Wed 9/17

4:31 pm-11:43 pm

1 stop7h 12m

$212

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

Knoxville McGhee Tyson

Mon 9/22

1:22 pm-8:40 am

1 stop19h 18m

$221

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

Knoxville McGhee Tyson

Wed 9/17

4:31 pm-8:14 am

2 stops15h 43m

$223

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/8

8:49 pm-12:55 pm

1 stop16h 06m

Knoxville McGhee Tyson

Fri 9/12

1:22 pm-10:40 pm

1 stop9h 18m

$225

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/22

7:10 am-8:59 pm

1 stop13h 49m

Knoxville McGhee Tyson

Wed 9/24

4:00 pm-8:15 am

1 stop16h 15m

$226

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

Knoxville McGhee Tyson

Mon 9/22

1:22 pm-8:40 am

1 stop19h 18m

$228

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 9/6

8:49 pm-2:29 pm

1 stop17h 40m

Knoxville McGhee Tyson

Tue 9/9

7:30 am-7:57 am

1 stop24h 27m

$231

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 9/4

11:49 am-7:50 pm

1 stop8h 01m

Knoxville McGhee Tyson

Sun 9/7

5:08 pm-12:46 am

1 stop7h 38m

$239

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Detroit to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of April is, on average, the cheapest month to fly to Knoxville from Detroit, with most prices found around $344. If you aren’t able to travel during the month of April, then book flights to Knoxville from Detroit during July instead. Flights to Knoxville in July, while not as cheap as those in April, still average around $399.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Detroit to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $399. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Detroit to Knoxville for around $497.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Detroit to Knoxville when you can find flight prices for as low as $422. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $478.

What is the cheapest Detroit to Knoxville McGhee Tyson flight route?

Fly from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson for the best Detroit - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $438 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Detroit for as low as $354 on momondo.

What cabin class options are available on Detroit to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Detroit to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit to Knoxville flights?

You could potentially save up to 63% on your flight if you consider stops on a Detroit to Knoxville flight.

How have Detroit to Knoxville flight prices changed over time?

When to book flights from Detroit to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Knoxville (DTT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Knoxville

Best Price Found

$248

Fastest flight time

1h 32m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Detroit in the past 72 hours is $248. The best round-trip flight deal from Detroit to Knoxville found on momondo in the last 72 hours is $399.
The fastest flight from Detroit to Knoxville takes 1h 32m
Direct flights go from Detroit to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Detroit to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 442.8 mi away from Detroit. Flights usually cover this in 7h 33m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Knoxville McGhee Tyson Airport?

    Prices for flights from Detroit to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Detroit to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Detroit to Knoxville?

  • What is the most popular airline from Detroit to Knoxville?

Best airlines flying from Detroit to Knoxville

Compare and see reviews for airlines that fly from Detroit to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
7.9
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $318Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Delta Flights From Detroit to Knoxville

    Delta flies from Detroit to Knoxville around 10 times per week, with 7,981 momondo users rating the airline 7.9/10. The cheapest Delta deal from Detroit to Knoxville in the last 72 hours was $309 (round-trip), much lower than the average airfare cost of $456 for Delta flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Lenoir City
Alcoa
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Knoxville?

It is quick and easy to find Detroit to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Detroit to Knoxville with flexible booking policies on momondo?

All flight searches from Detroit to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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