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Cheap flights from Des Moines to South Africa from $935

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to South Africa departing on 3/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:38 pm - 7:35 am
DSM
-
JNB
33h 57m
2 stops
American Airlines Logo
10:00 pm - 11:40 pm
JNB
-
DSM
32h 40m
2 stops
$1,134American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
1:38 pm - 7:35 am
DSM
-
JNB
33h 57m
2 stops
American Airlines Logo
10:00 pm - 11:40 pm
JNB
-
DSM
32h 40m
2 stops
$1,138American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
3:26 pm - 7:35 am
DSM
-
JNB
32h 09m
2 stops
American Airlines Logo
10:00 pm - 6:19 pm
JNB
-
DSM
27h 19m
2 stops
$1,139American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
2:00 pm - 7:35 am
DSM
-
JNB
33h 35m
2 stops
American Airlines Logo
10:00 pm - 6:19 pm
JNB
-
DSM
27h 19m
2 stops
$1,140American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
1:38 pm - 7:35 am
DSM
-
JNB
33h 57m
2 stops
American Airlines Logo
10:00 pm - 6:19 pm
JNB
-
DSM
27h 19m
2 stops
$1,141American Airlines
Wed, Mar 4 - Wed, Mar 11
Multiple Airlines Logo
1:38 pm - 7:35 am
DSM
-
JNB
33h 57m
2 stops
Multiple Airlines Logo
7:35 pm - 11:40 pm
JNB
-
DSM
35h 05m
2 stops
$1,185Multiple Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
2:00 pm - 7:35 am
DSM
-
JNB
33h 35m
2 stops
American Airlines Logo
10:00 pm - 11:40 pm
JNB
-
DSM
33h 40m
2 stops
$1,186American Airlines
Wed, Feb 18 - Wed, Feb 25
Multiple Airlines Logo
10:04 am - 10:25 am
DSM
-
JNB
40h 21m
2 stops
Multiple Airlines Logo
7:35 pm - 11:40 pm
JNB
-
DSM
35h 05m
2 stops
$1,189Multiple Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
1:38 pm - 10:25 am
DSM
-
JNB
36h 47m
2 stops
American Airlines Logo
10:00 pm - 11:40 pm
JNB
-
DSM
32h 40m
2 stops
$1,191American Airlines
Fri, Mar 6 - Fri, Mar 13
British Airways Logo
1:38 pm - 10:25 am
DSM
-
JNB
36h 47m
2 stops
British Airways Logo
10:00 pm - 10:34 pm
JNB
-
DSM
31h 34m
2 stops
$1,274British Airways
Tue, Mar 3 - Tue, Mar 10

American Airlines flights from Des Moines to South Africa

Our best American Airlines deals on Des Moines to South Africa flight tickets
American Airlines
Mar 4
DSM1:38 pmDes Moines
33h 57m
2 stops
JNB7:35 amJohannesburg OR Tambo
Mar 11
JNB10:00 pmJohannesburg OR Tambo
32h 40m
2 stops
DSM11:40 pmDes Moines
$1,134
American Airlines
Mar 4
DSM1:38 pmDes Moines
33h 57m
2 stops
JNB7:35 amJohannesburg OR Tambo
Mar 11
JNB10:00 pmJohannesburg OR Tambo
32h 40m
2 stops
DSM11:40 pmDes Moines
$1,138
American Airlines
Mar 4
DSM3:26 pmDes Moines
32h 09m
2 stops
JNB7:35 amJohannesburg OR Tambo
Mar 11
JNB10:00 pmJohannesburg OR Tambo
27h 19m
2 stops
DSM6:19 pmDes Moines
$1,139

Qatar Airways flights from Des Moines to South Africa

Our best Qatar Airways deals on Des Moines to South Africa flight tickets
Qatar Airways
Apr 5
DSM11:17 amDes Moines
33h 43m
2 stops
JNB4:00 amJohannesburg OR Tambo
Apr 12
JNB8:55 pmJohannesburg OR Tambo
34h 16m
2 stops
DSM12:11 amDes Moines
$1,324
Qatar Airways
Apr 5
DSM11:17 amDes Moines
33h 43m
2 stops
JNB4:00 amJohannesburg OR Tambo
Apr 12
JNB8:55 pmJohannesburg OR Tambo
34h 16m
2 stops
DSM12:11 amDes Moines
$1,325
Qatar Airways
Mar 5
DSM10:04 amDes Moines
33h 51m
2 stops
JNB3:55 amJohannesburg OR Tambo
Mar 12
JNB1:45 pmJohannesburg OR Tambo
32h 11m
2 stops
DSM2:56 pmDes Moines
$1,491

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Des Moines to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

1:38 pm-7:35 am

2 stops33h 57m

Johannesburg OR Tambo

Wed 3/11

10:00 pm-11:40 pm

2 stops32h 40m

$1,134

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

1:38 pm-7:35 am

2 stops33h 57m

Johannesburg OR Tambo

Wed 3/11

10:00 pm-11:40 pm

2 stops32h 40m

$1,138

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

3:26 pm-7:35 am

2 stops32h 09m

Johannesburg OR Tambo

Wed 3/11

10:00 pm-6:19 pm

2 stops27h 19m

$1,139

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

2:00 pm-7:35 am

2 stops33h 35m

Johannesburg OR Tambo

Wed 3/11

10:00 pm-6:19 pm

2 stops27h 19m

$1,140

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

1:38 pm-7:35 am

2 stops33h 57m

Johannesburg OR Tambo

Wed 3/11

10:00 pm-6:19 pm

2 stops27h 19m

$1,141

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

1:38 pm-7:35 am

2 stops33h 57m

Johannesburg OR Tambo

Wed 3/11

7:35 pm-11:40 pm

2 stops35h 05m

$1,185

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 2/18

2:00 pm-7:35 am

2 stops33h 35m

Johannesburg OR Tambo

Wed 2/25

10:00 pm-11:40 pm

2 stops33h 40m

$1,186

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

10:04 am-10:25 am

2 stops40h 21m

Johannesburg OR Tambo

Wed 3/11

7:35 pm-11:40 pm

2 stops35h 05m

$1,189

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 3/6

1:38 pm-10:25 am

2 stops36h 47m

Johannesburg OR Tambo

Fri 3/13

10:00 pm-11:40 pm

2 stops32h 40m

$1,191

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/3

1:38 pm-10:25 am

2 stops36h 47m

Johannesburg OR Tambo

Tue 3/10

10:00 pm-10:34 pm

2 stops31h 34m

$1,274

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Africa from

How to get the cheapest flight ticket from Des Moines to South Africa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to South Africa flights?

You could potentially save up to 21% on your flight if you consider stops on a Des Moines to South Africa flight.

Cheap Des Moines to South Africa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to South Africa

Fastest flight time

29h 31m

Direct flights

None
The fastest flight from Des Moines to South Africa takes 29h 31m
There are no direct flights from Des Moines to South Africa. There are no popular flight routes from Des Moines to South Africa.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to South Africa?

    Prices for flights from Des Moines Airport to South Africa refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to South Africa?

  • How old do you have to be to fly from Des Moines Airport to South Africa?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to South Africa.

  • What documentation or ID do you need to fly to South Africa?

    The required travel and health documents for your South Africa trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Africa. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Des Moines to South Africa

Compare and see reviews for airlines that fly from Des Moines to South Africa with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $1,410Free CancellationRating
7.9
8,076 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to South Africa?

It is quick and easy to find Des Moines to South Africa flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Africa that suits you.

Can I find flights from Des Moines to South Africa with flexible booking policies on momondo?

Yes. All flights to South Africa from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to South Africa?

Once you have performed a search for Des Moines to South Africa flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to South Africa right now. Can momondo alert me if prices change?

Price alerts on flights to South Africa from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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