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Cheap flights from Columbia to Des Moines from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia to Des Moines departing on 6/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 am - 10:11 am
CAE
-
DSM
4h 41m
1 stop
United Airlines Logo
6:15 am - 2:12 pm
DSM
-
CAE
6h 57m
1 stop
$300United Airlines
Wed, Sep 23 - Sun, Sep 27
United Airlines Logo
2:40 pm - 9:12 pm
CAE
-
DSM
7h 32m
2 stops
United Airlines Logo
6:15 am - 2:12 pm
DSM
-
CAE
6h 57m
1 stop
$317United Airlines
Wed, Sep 23 - Sun, Sep 27
American Airlines Logo
6:00 am - 1:20 pm
CAE
-
DSM
8h 20m
1 stop
American Airlines Logo
7:11 am - 4:51 pm
DSM
-
CAE
8h 40m
1 stop
$329American Airlines
Sat, May 9 - Mon, May 11
American Airlines Logo
6:00 am - 12:55 pm
CAE
-
DSM
7h 55m
1 stop
American Airlines Logo
7:11 am - 4:51 pm
DSM
-
CAE
8h 40m
1 stop
$349American Airlines
Tue, Apr 28 - Tue, May 5
American Airlines Logo
3:41 pm - 11:49 pm
CAE
-
DSM
9h 08m
2 stops
American Airlines Logo
7:11 am - 4:51 pm
DSM
-
CAE
8h 40m
1 stop
$354American Airlines
Tue, Apr 28 - Tue, May 5
Delta Logo
6:40 am - 11:08 am
CAE
-
DSM
5h 28m
1 stop
Delta Logo
5:27 am - 1:14 pm
DSM
-
CAE
6h 47m
1 stop
$364Delta
Thu, May 7 - Sat, May 9
American Airlines Logo
6:00 am - 12:55 pm
CAE
-
DSM
7h 55m
1 stop
American Airlines Logo
5:00 am - 11:58 am
DSM
-
CAE
5h 58m
1 stop
$371American Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
6:00 am - 12:55 pm
CAE
-
DSM
7h 55m
1 stop
American Airlines Logo
6:00 am - 3:46 pm
DSM
-
CAE
8h 46m
2 stops
$376American Airlines
Thu, May 7 - Sat, May 9
American Airlines Logo
6:00 am - 12:55 pm
CAE
-
DSM
7h 55m
1 stop
American Airlines Logo
6:00 am - 3:46 pm
DSM
-
CAE
8h 46m
2 stops
$405American Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
6:00 am - 12:55 pm
CAE
-
DSM
7h 55m
1 stop
American Airlines Logo
6:00 am - 3:46 pm
DSM
-
CAE
8h 46m
2 stops
$447American Airlines
Thu, May 7 - Sun, May 10

American Airlines flights from Columbia to Des Moines

Our best American Airlines deals on Columbia to Des Moines flight tickets
American Airlines
May 9
CAE6:00 amColumbia Metropolitan
8h 20m
1 stop
DSM1:20 pmDes Moines
May 11
DSM7:11 amDes Moines
8h 40m
1 stop
CAE4:51 pmColumbia Metropolitan
$329
American Airlines
Apr 28
CAE6:00 amColumbia Metropolitan
7h 55m
1 stop
DSM12:55 pmDes Moines
May 5
DSM7:11 amDes Moines
8h 40m
1 stop
CAE4:51 pmColumbia Metropolitan
$349
American Airlines
Apr 28
CAE3:41 pmColumbia Metropolitan
9h 08m
2 stops
DSM11:49 pmDes Moines
May 5
DSM7:11 amDes Moines
8h 40m
1 stop
CAE4:51 pmColumbia Metropolitan
$354

United Airlines flights from Columbia to Des Moines

Our best United Airlines deals on Columbia to Des Moines flight tickets
United Airlines
Sep 23
CAE6:30 amColumbia Metropolitan
4h 41m
1 stop
DSM10:11 amDes Moines
Sep 27
DSM6:15 amDes Moines
6h 57m
1 stop
CAE2:12 pmColumbia Metropolitan
$300
United Airlines
Sep 23
CAE2:40 pmColumbia Metropolitan
7h 32m
2 stops
DSM9:12 pmDes Moines
Sep 27
DSM6:15 amDes Moines
6h 57m
1 stop
CAE2:12 pmColumbia Metropolitan
$317
United Airlines
Apr 25
CAE2:38 pmColumbia Metropolitan
9h 39m
2 stops
DSM11:17 pmDes Moines
Apr 29
DSM11:25 amDes Moines
4h 30m
1 stop
CAE4:55 pmColumbia Metropolitan
$479

momondo Fare Finder

 
Customize your flight search to find flights from Columbia to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 14, 2026.
Use the filters below to find and compare flights from Columbia to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Wed 9/23

6:30 am-10:11 am

1 stop4h 41m

Des Moines

Sun 9/27

6:15 am-2:12 pm

1 stop6h 57m

$300

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Wed 9/23

2:40 pm-9:12 pm

2 stops7h 32m

Des Moines

Sun 9/27

6:15 am-2:12 pm

1 stop6h 57m

$317

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Sat 5/9

6:00 am-1:20 pm

1 stop8h 20m

Des Moines

Mon 5/11

7:11 am-4:51 pm

1 stop8h 40m

$329

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Tue 4/28

6:00 am-12:55 pm

1 stop7h 55m

Des Moines

Tue 5/5

7:11 am-4:51 pm

1 stop8h 40m

$349

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Tue 4/28

3:41 pm-11:49 pm

2 stops9h 08m

Des Moines

Tue 5/5

7:11 am-4:51 pm

1 stop8h 40m

$354

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Thu 5/7

6:40 am-11:08 am

1 stop5h 28m

Des Moines

Sat 5/9

5:27 am-1:14 pm

1 stop6h 47m

$364

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Thu 5/7

6:00 am-12:55 pm

1 stop7h 55m

Des Moines

Sun 5/10

5:00 am-11:58 am

1 stop5h 58m

$371

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Thu 5/7

6:00 am-12:55 pm

1 stop7h 55m

Des Moines

Sat 5/9

6:00 am-3:46 pm

2 stops8h 46m

$376

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Thu 5/7

6:00 am-12:55 pm

1 stop7h 55m

Des Moines

Sun 5/10

6:00 am-3:46 pm

2 stops8h 46m

$405

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Thu 5/7

6:00 am-12:55 pm

1 stop7h 55m

Des Moines

Sun 5/10

6:00 am-3:46 pm

2 stops8h 46m

$447

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Columbia to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbia and Des Moines?

When to book flights from Columbia to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia to Des Moines (CAE to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia to Des Moines

Fastest flight time

5h 07m

Direct flights

None
The fastest flight from Columbia to Des Moines takes 5h 07m
There are no direct flights from Columbia to Des Moines. There are no popular flight routes from Columbia to Des Moines.
Search flight deals

Frequently asked questions about flying from Columbia to Des Moines

  • How far is Columbia Metropolitan to Des Moines by plane?

    Columbia Metropolitan and Des Moines are 862.4 mi apart from one another. A reasonable flight in good conditions will take 5h 07m.

  • When did momondo last update prices for flights from Columbia Metropolitan Airport to Des Moines Airport?

    Prices for flights from Columbia Metropolitan Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Columbia Metropolitan Airport to Des Moines Airport?

  • How old do you have to be to fly from Columbia Metropolitan Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Metropolitan Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Columbia to Des Moines?

Best airlines flying from Columbia to Des Moines

Compare and see reviews for airlines that fly from Columbia to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,573 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,406 reviews
Search Delta flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Des Moines?

It is quick and easy to find Columbia to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Columbia to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Columbia on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbia to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Columbia and alert you when they change.

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