When did momondo last update prices for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport were last updated today.

How many operators does momondo search for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport?

There is 1 operator available for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport as of December 2025.

How old do you have to be to fly from Columbia Regional Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$278 Cheap Flights from Columbia to Knoxville in 2025/26

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Find the cheapest flights from Columbia, Missouri to Knoxville

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Cheap round-trip flights

Enter your travel dates to find the best prices.

3:10 pm - 8:52 pm

COU

TYS

4h 42m1 stop

11:10 am - 2:35 pm

TYS

COU

4h 25m1 stop

$278United Airlines

Sat, Jan 31 - Wed, Feb 4

8:45 am - 11:44 pm

COU

TYS

13h 59m2 stops

5:29 pm - 9:37 pm

TYS

COU

5h 08m1 stop

$284United Airlines

Sat, Jan 31 - Wed, Feb 4

11:17 am - 11:44 pm

COU

TYS

11h 27m2 stops

2:25 pm - 9:37 pm

TYS

COU

8h 12m2 stops

$289United Airlines

Sat, Jan 31 - Wed, Feb 4

6:34 pm - 10:39 pm

COU

TYS

27h 05m1 stop

11:00 am - 5:25 pm

TYS

COU

7h 25m1 stop

$453United Airlines

Sat, Dec 20 - Wed, Dec 24

3:19 pm - 9:31 pm

COU

TYS

5h 12m1 stop

5:42 am - 2:49 pm

TYS

COU

10h 07m2 stops

$476American Airlines

Sat, Dec 20 - Wed, Dec 24

6:34 pm - 10:56 am

COU

TYS

15h 22m2 stops

9:50 am - 5:25 pm

TYS

COU

8h 35m2 stops

$508United Airlines

Sat, Dec 20 - Wed, Dec 24

United Airlines flights from Columbia, Missouri to Knoxville

Our best United Airlines deals on Columbia, Missouri to Knoxville flight tickets

United Airlines

Jan 31

COU8:09 amColumbia Regional

4h 15m

1 stop

TYS1:24 pmKnoxville McGhee Tyson

Feb 4

TYS11:10 amKnoxville McGhee Tyson

4h 25m

1 stop

COU2:35 pmColumbia Regional

$278

Find similar

United Airlines

Jan 31

COU8:45 amColumbia Regional

13h 59m

2 stops

TYS11:44 pmKnoxville McGhee Tyson

Feb 4

TYS5:29 pmKnoxville McGhee Tyson

5h 08m

1 stop

COU9:37 pmColumbia Regional

$284

Find similar

United Airlines

Jan 31

COU11:17 amColumbia Regional

11h 27m

2 stops

TYS11:44 pmKnoxville McGhee Tyson

Feb 4

TYS2:25 pmKnoxville McGhee Tyson

8h 12m

2 stops

COU9:37 pmColumbia Regional

$289

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Columbia, Missouri to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 1/31

3:10 pm-8:52 pm

1 stop4h 42m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-2:35 pm

1 stop4h 25m

$278

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 1/31

8:45 am-11:44 pm

2 stops13h 59m

Knoxville McGhee Tyson

Wed 2/4

5:29 pm-9:37 pm

1 stop5h 08m

$284

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 1/31

11:17 am-11:44 pm

2 stops11h 27m

Knoxville McGhee Tyson

Wed 2/4

2:25 pm-9:37 pm

2 stops8h 12m

$289

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 12/20

6:34 pm-10:39 pm

1 stop27h 05m

Knoxville McGhee Tyson

Wed 12/24

11:00 am-5:25 pm

1 stop7h 25m

$453

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 12/20

3:19 pm-9:31 pm

1 stop5h 12m

Knoxville McGhee Tyson

Wed 12/24

5:42 am-2:49 pm

2 stops10h 07m

$476

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 12/20

6:34 pm-10:56 am

2 stops15h 22m

Knoxville McGhee Tyson

Wed 12/24

9:50 am-5:25 pm

2 stops8h 35m

$508

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Columbia, Missouri to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Columbia, Missouri to Knoxville when you can find flight prices for as low as $539. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $610.

When to book flights from Columbia, Missouri to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Columbia, Missouri to Knoxville (COU to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Knoxville

Fastest flight time	4h 42m
Direct flights	None

The fastest flight from Columbia, Missouri to Knoxville takes 4h 42m

There are no direct flights from Columbia, Missouri to Knoxville. There are no popular flight routes from Columbia, Missouri to Knoxville.

Search flight deals

How far is Columbia Regional to Knoxville McGhee Tyson by plane?
The distance between Columbia Regional and Knoxville McGhee Tyson is about 505.0 mi. Typically, this will take 4h 15m by plane in normal conditions.
When did momondo last update prices for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport were last updated today.
How many operators does momondo search for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport?
There is 1 operator available for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport as of December 2025.
How old do you have to be to fly from Columbia Regional Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Columbia, Missouri to Knoxville?
Based on momondo bookings for flights between Columbia, Missouri and Knoxville, the leading airline is American Airlines, making up 100% of the total bookings.

Best airlines flying from Columbia, Missouri to Knoxville

Compare and see reviews for airlines that fly from Columbia, Missouri to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $430	Free Cancellation	Rating 7.2 11,046 reviews		Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Maryville

Crossville

Murphy

Alcoa

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Columbia.

Can I find flights from Columbia to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Knoxville?

momondo helps you find the best flight between Columbia and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Columbia to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Columbia to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.