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Cheap flights from Columbia, Missouri to Knoxville from $247

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbia, Missouri to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
2:49 pm - 10:20 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
6h 31m1 stop Valparaiso Destin-Ft Walton Beach
Allegiant Air Logo
7:30 pm - 1:37 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
19h 07m1 stop Valparaiso Destin-Ft Walton Beach
$247Allegiant Air
Mon, Oct 5 - Thu, Oct 15
Allegiant Air Logo
2:49 pm - 10:20 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
6h 31m1 stop Valparaiso Destin-Ft Walton Beach
Allegiant Air Logo
9:26 am - 7:43 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
11h 17m1 stop Valparaiso Destin-Ft Walton Beach
$251Allegiant Air
Mon, Oct 5 - Fri, Oct 9
Allegiant Air Logo
12:29 pm - 9:39 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
8h 10m1 stop Orlando Sanford Intl
Allegiant Air Logo
2:01 pm - 2:16 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
25h 15m1 stop Valparaiso Destin-Ft Walton Beach
$281Allegiant Air
Mon, Oct 19 - Thu, Oct 29
Allegiant Air Logo
12:59 pm - 9:41 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
7h 42m1 stop Orlando Sanford Intl
Allegiant Air Logo
2:01 pm - 2:16 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
25h 15m1 stop Valparaiso Destin-Ft Walton Beach
$284Allegiant Air
Fri, Oct 23 - Thu, Oct 29
Allegiant Air Logo
2:49 pm - 10:20 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
6h 31m1 stop Valparaiso Destin-Ft Walton Beach
Allegiant Air Logo
7:30 pm - 7:43 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
25h 13m1 stop Valparaiso Destin-Ft Walton Beach
$294Allegiant Air
Mon, Oct 5 - Thu, Oct 8
Allegiant Air Logo
12:29 pm - 9:39 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
8h 10m1 stop Orlando Sanford Intl
Allegiant Air Logo
7:00 am - 10:43 amTYS  Knoxville McGhee Tyson-COU Columbia Regional
28h 43m1 stop Orlando Sanford Intl
$298Allegiant Air
Mon, Oct 19 - Sun, Oct 25
Allegiant Air Logo
12:59 pm - 9:41 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
7h 42m1 stop Orlando Sanford Intl
Allegiant Air Logo
7:00 am - 10:43 amTYS  Knoxville McGhee Tyson-COU Columbia Regional
28h 43m1 stop Orlando Sanford Intl
$301Allegiant Air
Fri, Oct 23 - Sun, Oct 25
American Airlines Logo
6:26 pm - 11:47 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
4h 21m1 stop Chicago O'Hare Intl
American Airlines Logo
7:14 pm - 10:42 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
4h 28m1 stop Charlotte Douglas
$308American Airlines
Fri, Nov 6 - Mon, Nov 9
American Airlines Logo
8:16 am - 1:33 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
4h 17m1 stop Charlotte Douglas
American Airlines Logo
6:06 pm - 10:08 pmTYS  Knoxville McGhee Tyson-COU Columbia Regional
5h 02m1 stop Charlotte Douglas
$318American Airlines
Sat, Sep 26 - Wed, Sep 30
United Airlines Logo
3:19 pm - 11:59 pmCOU  Columbia Regional-TYS Knoxville McGhee Tyson
7h 40m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
United Airlines Logo
6:00 am - 10:39 amTYS  Knoxville McGhee Tyson-COU Columbia Regional
5h 39m1 stop Chicago O'Hare Intl
$324United Airlines
Sat, Sep 26 - Wed, Sep 30

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United Airlines flights from Columbia, Missouri to Knoxville

Our best United Airlines deals on Columbia, Missouri to Knoxville flight tickets
United Airlines
Sep 26
COU3:19 pmColumbia Regional
7h 40m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
Sep 30
TYS6:00 amKnoxville McGhee Tyson
5h 39m
1 stop
COU10:39 amColumbia Regional
$324
United Airlines
Jan 30
COU8:00 amColumbia Regional
10h 51m
2 stops
TYS7:51 pmKnoxville McGhee Tyson
Feb 3
TYS10:45 amKnoxville McGhee Tyson
4h 38m
1 stop
COU2:23 pmColumbia Regional
$384
United Airlines
Jan 30
COU8:00 amColumbia Regional
10h 51m
3 stops
TYS7:51 pmKnoxville McGhee Tyson
Feb 3
TYS10:45 amKnoxville McGhee Tyson
4h 38m
1 stop
COU2:23 pmColumbia Regional
$389

Allegiant Air flights from Columbia, Missouri to Knoxville

Our best Allegiant Air deals on Columbia, Missouri to Knoxville flight tickets
Allegiant Air
Oct 5
COU2:49 pmColumbia Regional
6h 31m
1 stop
TYS10:20 pmKnoxville McGhee Tyson
Oct 15
TYS7:30 pmKnoxville McGhee Tyson
19h 07m
1 stop
COU1:37 pmColumbia Regional
$247
Allegiant Air
Oct 5
COU2:49 pmColumbia Regional
6h 31m
1 stop
TYS10:20 pmKnoxville McGhee Tyson
Oct 9
TYS9:26 amKnoxville McGhee Tyson
11h 17m
1 stop
COU7:43 pmColumbia Regional
$251
Allegiant Air
Oct 19
COU12:29 pmColumbia Regional
8h 10m
1 stop
TYS9:39 pmKnoxville McGhee Tyson
Oct 29
TYS2:01 pmKnoxville McGhee Tyson
25h 15m
1 stop
COU2:16 pmColumbia Regional
$281

momondo Fare Finder

 
Use the filters below to find and compare flights from Columbia, Missouri to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/5

2:49 pm-10:20 pm

1 stop6h 31m

Knoxville McGhee Tyson

Thu 10/15

7:30 pm-1:37 pm

1 stop19h 07m

$247

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/5

2:49 pm-10:20 pm

1 stop6h 31m

Knoxville McGhee Tyson

Fri 10/9

9:26 am-7:43 pm

1 stop11h 17m

$251

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/19

12:29 pm-9:39 pm

1 stop8h 10m

Knoxville McGhee Tyson

Thu 10/29

2:01 pm-2:16 pm

1 stop25h 15m

$281

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Fri 10/23

12:59 pm-9:41 pm

1 stop7h 42m

Knoxville McGhee Tyson

Thu 10/29

2:01 pm-2:16 pm

1 stop25h 15m

$284

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/5

2:49 pm-10:20 pm

1 stop6h 31m

Knoxville McGhee Tyson

Thu 10/8

7:30 pm-7:43 pm

1 stop25h 13m

$294

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/19

12:29 pm-9:39 pm

1 stop8h 10m

Knoxville McGhee Tyson

Sun 10/25

7:00 am-10:43 am

1 stop28h 43m

$298

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Fri 10/23

12:59 pm-9:41 pm

1 stop7h 42m

Knoxville McGhee Tyson

Sun 10/25

7:00 am-10:43 am

1 stop28h 43m

$301
Quickest round-trip

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Fri 11/6

6:26 pm-11:47 pm

1 stop4h 21m

Knoxville McGhee Tyson

Mon 11/9

7:14 pm-10:42 pm

1 stop4h 28m

$308

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Sat 9/26

8:16 am-1:33 pm

1 stop4h 17m

Knoxville McGhee Tyson

Wed 9/30

6:06 pm-10:08 pm

1 stop5h 02m

$318

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Sat 9/26

3:19 pm-11:59 pm

2 stops7h 40m

Knoxville McGhee Tyson

Wed 9/30

6:00 am-10:39 am

1 stop5h 39m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Columbia, Missouri to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Columbia Regional to Knoxville McGhee Tyson?

American Airlines and United Airlines are the most popular carriers operating from Columbia Regional to Knoxville McGhee Tyson

When to book flights from Columbia, Missouri to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Knoxville (COU to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Knoxville

Best Price Found

$477

Fastest flight time

5h 59m

Direct flights

None
The best one-way flight to Knoxville from Columbia, Missouri in the past 72 hours is $477. The best round-trip flight deal from Columbia, Missouri to Knoxville found on momondo in the last 72 hours is $247.
The fastest flight from Columbia, Missouri to Knoxville takes 5h 59m
There are no direct flights from Columbia, Missouri to Knoxville. There are no popular flight routes from Columbia, Missouri to Knoxville.
Search flight deals

Frequently asked questions about flying from Columbia, Missouri to Knoxville

  • How far is Columbia Regional to Knoxville McGhee Tyson by plane?

    The distance between Columbia Regional and Knoxville McGhee Tyson is about 505.0 mi. Typically, this will take 5h 59m by plane in normal conditions.

  • When did momondo last update prices for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Columbia Regional Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Knoxville?

Best airlines flying from Columbia, Missouri to Knoxville

Compare and see reviews for airlines that fly from Columbia, Missouri to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $288Free CancellationRating
7.1
12,062 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Columbia.

Can I find flights from Columbia to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Knoxville?

momondo helps you find the best flight between Columbia and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

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