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Cheap flights from Columbia, Missouri to Buffalo from $453

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Buffalo departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Columbia, Missouri to Buffalo

Cheap round-trip flights

Multiple Airlines Logo
COU-BUF
758 mimulti-stop
Multiple Airlines Logo
BUF-COU
758 mimulti-stop
Multiple Airlines
Find Deal

American Airlines flights from Columbia, Missouri to Buffalo

Our best American Airlines deals on Columbia, Missouri to Buffalo flight tickets
American Airlines
Aug 21
COU11:39 amColumbia Regional
4h 31m
1 stop
BUF5:10 pmBuffalo
Aug 25
BUF5:40 pmBuffalo
4h 53m
1 stop
COU9:33 pmColumbia Regional
$536
Find similar
American Airlines
Aug 21
COU6:15 amColumbia Regional
8h 27m
2 stops
BUF3:42 pmBuffalo
Aug 25
BUF6:29 amBuffalo
5h 40m
1 stop
COU11:09 amColumbia Regional
$542
Find similar
American Airlines
Aug 21
COU11:39 amColumbia Regional
10h 52m
2 stops
BUF11:31 pmBuffalo
Aug 24
BUF1:46 pmBuffalo
8h 47m
2 stops
COU9:33 pmColumbia Regional
$547
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 20, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

mié. 10/15

8:00 am-10:42 pm

2 stops13h 42m

$453

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

mié. 10/15

8:00 am-9:13 pm

1 stop12h 13m

$515

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Columbia, Missouri to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Tuesday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $519. Flights from Columbia, Missouri to Buffalo on a Wednesday will generally be more expensive and average around $555. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

In the morning is the cheapest time of day to fly from Columbia, Missouri to Buffalo when you can find flight prices for as low as $570. Flying to Buffalo in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $648 per ticket.

When to book flights from Columbia, Missouri to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Buffalo (COU to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Buffalo

Direct flights

None
There are no direct flights from Columbia, Missouri to Buffalo. There are no popular flight routes from Columbia, Missouri to Buffalo.
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  • How far is Columbia Regional to Buffalo by plane?

    The straight-line distance from Columbia Regional to Buffalo is 751.7 mi.

  • When did momondo last update prices for flights from Columbia Regional Airport to Buffalo Airport?

    Prices for flights from Columbia Regional Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Columbia Regional Airport to Buffalo Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Buffalo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbia Regional Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Columbia, Missouri to Buffalo?

Best airlines flying from Columbia, Missouri to Buffalo

Compare and see reviews for airlines that fly from Columbia, Missouri to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $406Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Tonawanda
Amherst
Williamsville
Grand Island
Lockport
Orchard Park
West Seneca
East Aurora
Eden
Angola
Bowmansville

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Buffalo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Buffalo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Buffalo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Buffalo from Columbia with this policy.

How can momondo help me find flights from Columbia to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Buffalo right now. Can momondo alert me if prices change?

Price alerts on flights to Buffalo from Columbia are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
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lun. 9/1
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