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Cheap flights from Columbia, Missouri to Buffalo from $328

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Buffalo departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia, Missouri to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:00 am - 1:13 pm
COU
-
BUF
4h 13m
1 stop
United Airlines Logo
7:00 am - 10:55 am
BUF
-
COU
4h 55m
1 stop
$328United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
8:00 am - 1:13 pm
COU
-
BUF
4h 13m
1 stop
United Airlines Logo
11:02 am - 8:49 pm
BUF
-
COU
10h 47m
2 stops
$334United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
9:02 am - 11:33 pm
COU
-
BUF
13h 31m
2 stops
United Airlines Logo
11:02 am - 8:49 pm
BUF
-
COU
10h 47m
2 stops
$339United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
3:23 pm - 8:43 pm
COU
-
BUF
4h 20m
1 stop
United Airlines Logo
5:55 pm - 10:03 pm
BUF
-
COU
5h 08m
1 stop
$354United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
11:30 am - 11:33 pm
COU
-
BUF
11h 03m
2 stops
United Airlines Logo
6:00 am - 2:48 pm
BUF
-
COU
9h 48m
2 stops
$364United Airlines
Tue, Apr 7 - Wed, Apr 22
United Airlines Logo
9:02 am - 8:43 pm
COU
-
BUF
10h 41m
2 stops
United Airlines Logo
6:00 am - 2:48 pm
BUF
-
COU
9h 48m
2 stops
$389United Airlines
Wed, Apr 22 - Sat, Apr 25
United Airlines Logo
2:41 pm - 8:46 pm
COU
-
BUF
5h 05m
1 stop
United Airlines Logo
5:29 pm - 9:33 pm
BUF
-
COU
5h 04m
1 stop
$656United Airlines
Sun, Mar 15 - Thu, Mar 19
American Airlines Logo
6:30 pm - 11:40 pm
COU
-
BUF
4h 10m
1 stop
American Airlines Logo
8:00 am - 6:00 pm
BUF
-
COU
11h 00m
2 stops
$662American Airlines
Sun, Mar 15 - Thu, Mar 19
American Airlines Logo
10:08 am - 8:29 pm
COU
-
BUF
9h 21m
2 stops
American Airlines Logo
7:23 am - 6:00 pm
BUF
-
COU
11h 37m
2 stops
$783American Airlines
Sun, Mar 15 - Thu, Mar 19

American Airlines flights from Columbia, Missouri to Buffalo

Our best American Airlines deals on Columbia, Missouri to Buffalo flight tickets
American Airlines
Mar 8
COU6:00 amColumbia Regional
4h 49m
1 stop
BUF11:49 amBuffalo
Mar 15
BUF6:09 amBuffalo
4h 21m
1 stop
COU9:30 amColumbia Regional
$298
American Airlines
Mar 8
COU6:00 amColumbia Regional
8h 54m
2 stops
BUF3:54 pmBuffalo
Mar 15
BUF6:09 amBuffalo
4h 21m
1 stop
COU9:30 amColumbia Regional
$364
American Airlines
Mar 15
COU6:30 pmColumbia Regional
4h 10m
1 stop
BUF11:40 pmBuffalo
Mar 19
BUF8:00 amBuffalo
11h 00m
2 stops
COU6:00 pmColumbia Regional
$662

United Airlines flights from Columbia, Missouri to Buffalo

Our best United Airlines deals on Columbia, Missouri to Buffalo flight tickets
United Airlines
Apr 28
COU8:00 amColumbia Regional
4h 13m
1 stop
BUF1:13 pmBuffalo
May 2
BUF7:00 amBuffalo
4h 55m
1 stop
COU10:55 amColumbia Regional
$328
United Airlines
Apr 28
COU8:00 amColumbia Regional
4h 13m
1 stop
BUF1:13 pmBuffalo
May 2
BUF11:02 amBuffalo
10h 47m
2 stops
COU8:49 pmColumbia Regional
$334
United Airlines
Apr 28
COU9:02 amColumbia Regional
13h 31m
2 stops
BUF11:33 pmBuffalo
May 2
BUF11:02 amBuffalo
10h 47m
2 stops
COU8:49 pmColumbia Regional
$339

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/28

8:00 am-1:13 pm

1 stop4h 13m

Buffalo

Sat 5/2

7:00 am-10:55 am

1 stop4h 55m

$328

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/28

8:00 am-1:13 pm

1 stop4h 13m

Buffalo

Sat 5/2

11:02 am-8:49 pm

2 stops10h 47m

$334

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/28

9:02 am-11:33 pm

2 stops13h 31m

Buffalo

Sat 5/2

11:02 am-8:49 pm

2 stops10h 47m

$339

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/28

3:23 pm-8:43 pm

1 stop4h 20m

Buffalo

Sat 5/2

5:55 pm-10:03 pm

1 stop5h 08m

$354

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/7

11:30 am-11:33 pm

2 stops11h 03m

Buffalo

Wed 4/22

6:00 am-2:48 pm

2 stops9h 48m

$364

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Wed 4/22

9:02 am-8:43 pm

2 stops10h 41m

Buffalo

Sat 4/25

6:00 am-2:48 pm

2 stops9h 48m

$389

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Sun 3/15

2:41 pm-8:46 pm

1 stop5h 05m

Buffalo

Thu 3/19

5:29 pm-9:33 pm

1 stop5h 04m

$656

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Sun 3/15

6:30 pm-11:40 pm

1 stop4h 10m

Buffalo

Thu 3/19

8:00 am-6:00 pm

2 stops11h 00m

$662

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Sun 3/15

10:08 am-8:29 pm

2 stops9h 21m

Buffalo

Thu 3/19

7:23 am-6:00 pm

2 stops11h 37m

$783

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Columbia, Missouri to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Buffalo (COU to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Buffalo

Fastest flight time

4h 20m

Direct flights

None
The fastest flight from Columbia, Missouri to Buffalo takes 4h 20m
There are no direct flights from Columbia, Missouri to Buffalo. There are no popular flight routes from Columbia, Missouri to Buffalo.
Search flight deals

  • How far is Columbia Regional to Buffalo by plane?

    The straight-line distance from Columbia Regional to Buffalo is 751.7 mi. Flights usually cover this in 4h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Buffalo Airport?

    Prices for flights from Columbia Regional Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Columbia Regional Airport to Buffalo Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Buffalo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbia Regional Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Columbia, Missouri to Buffalo?

Best airlines flying from Columbia, Missouri to Buffalo

Compare and see reviews for airlines that fly from Columbia, Missouri to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $268Free CancellationRating
7.4
9,375 reviews
Search United Airlines flights

  • How do I get Price Alerts for flights from Columbia, Missouri to Buffalo?

    Price Alerts will notify you by email when the price for flights to Buffalo from Columbia, Missouri decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.

  • How can I save money on flights from Columbia, Missouri to Buffalo with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We compare prices from 700+ competitors to help you find the price that works best for you. momondo operates in over 30 international markets, bringing you access to a wide range of fares and deals. Search for your travel using momondo for a diverse range of options from airlines and OTAs.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Grand Island
Tonawanda
Williamsville
Orchard Park
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Buffalo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Buffalo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Buffalo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Buffalo from Columbia with this policy.

How can momondo help me find flights from Columbia to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Buffalo right now. Can momondo alert me if prices change?

Price alerts on flights to Buffalo from Columbia are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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