Cheap flights from Chicago to Prague from $268

In general, February is the cheapest month to fly from Chicago to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $576. If you are unable to visit Prague during the month of February, then departing from Chicago during the month January is also very affordable. Most momondo users find prices during this month for around $645.

You are more likely to see cheaper flights to Prague from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Prague for around $779 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Prague from Chicago for as low as $660 on momondo.

You could potentially save up to 14% on your flight if you consider stops on a Chicago to Prague flight.

As of October 2026, prices for Chicago to Prague flights are approximately 27% cheaper when compared to flights at the same time last year.

Air Serbia, SWISS, and British Airways are the most popular carriers operating from Chicago to Václav Havel Prague

Scandinavian Airlines, Lufthansa and United Airlines are the top three most popular airlines that fly to Prague from Chicago according to our data. Scandinavian Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 11 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

Dublin (DUB) was the most common stop: 36% of momondo users choosing 1-stop flights on this route connected there.

Flights via Istanbul (IST) offer the lowest average round-trip price of $592.

Flights connecting via Zurich (ZRH) have the shortest average one-way travel time: 10h 55m.

Paris (CDG) has the shortest average layover time for this route: 1h 30m.