Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Charleston to Knoxville from $139

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Knoxville departing on 7/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:47 pm - 8:36 am
CHS
-
TYS
12h 49m
1 stop
Multiple Airlines Logo
6:29 pm - 8:38 am
TYS
-
CHS
14h 09m
1 stop
$216Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
7:47 pm - 8:36 am
CHS
-
TYS
12h 49m
1 stop
Multiple Airlines Logo
6:29 pm - 8:38 am
TYS
-
CHS
14h 09m
1 stop
$226Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
8:20 pm - 8:36 am
CHS
-
TYS
12h 16m
2 stops
Multiple Airlines Logo
6:29 pm - 8:38 am
TYS
-
CHS
14h 09m
1 stop
$230Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
American Airlines Logo
6:41 am - 10:38 am
CHS
-
TYS
3h 57m
1 stop
American Airlines Logo
11:03 am - 2:41 pm
TYS
-
CHS
3h 38m
1 stop
$233American Airlines
Tue, Jul 28 - Tue, Aug 4
Multiple Airlines Logo
8:20 pm - 8:36 am
CHS
-
TYS
12h 16m
2 stops
Multiple Airlines Logo
6:29 pm - 8:38 am
TYS
-
CHS
14h 09m
1 stop
$235Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Southwest Logo
6:35 am - 5:00 pm
CHS
-
TYS
10h 25m
2 stops
Southwest Logo
7:00 am - 12:50 pm
TYS
-
CHS
5h 50m
1 stop
$238Southwest
Tue, Jul 28 - Tue, Aug 4
Multiple Airlines Logo
3:23 pm - 11:33 pm
CHS
-
TYS
8h 10m
1 stop
Multiple Airlines Logo
2:25 pm - 8:38 am
TYS
-
CHS
18h 13m
1 stop
$239Multiple Airlines
Mon, Aug 3 - Wed, Aug 5
American Airlines Logo
2:06 pm - 5:34 pm
CHS
-
TYS
3h 28m
1 stop
American Airlines Logo
7:25 pm - 11:00 pm
TYS
-
CHS
3h 35m
1 stop
$247American Airlines
Sat, Aug 15 - Mon, Aug 17
Southwest Logo
6:35 am - 5:00 pm
CHS
-
TYS
10h 25m
2 stops
Southwest Logo
7:00 am - 7:15 pm
TYS
-
CHS
12h 15m
2 stops
$249Southwest
Tue, Jul 28 - Tue, Aug 4
American Airlines Logo
6:11 am - 9:43 am
CHS
-
TYS
3h 32m
1 stop
American Airlines Logo
5:15 am - 9:39 am
TYS
-
CHS
4h 24m
1 stop
$259American Airlines
Thu, Aug 13 - Mon, Aug 17

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Delta flights from Charleston to Knoxville

Our best Delta deals on Charleston to Knoxville flight tickets
Delta
Sep 4
CHS6:45 pmCharleston
5h 07m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Sep 7
TYS7:30 amKnoxville McGhee Tyson
5h 41m
1 stop
CHS1:11 pmCharleston
$369
Delta
Sep 4
CHS6:45 pmCharleston
5h 07m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Sep 7
TYS5:40 amKnoxville McGhee Tyson
4h 28m
1 stop
CHS10:08 amCharleston
$415
Delta
Jul 2
CHS6:15 amCharleston
3h 23m
1 stop
TYS9:38 amKnoxville McGhee Tyson
Jul 5
TYS5:40 amKnoxville McGhee Tyson
3h 20m
1 stop
CHS9:00 amCharleston
$617

United Airlines flights from Charleston to Knoxville

Our best United Airlines deals on Charleston to Knoxville flight tickets
United Airlines
Oct 24
CHS6:00 amCharleston
8h 42m
1 stop
TYS2:42 pmKnoxville McGhee Tyson
Oct 28
TYS5:45 amKnoxville McGhee Tyson
8h 28m
1 stop
CHS2:13 pmCharleston
$437
United Airlines
Oct 24
CHS6:00 amCharleston
15h 00m
2 stops
TYS9:00 pmKnoxville McGhee Tyson
Oct 28
TYS5:45 amKnoxville McGhee Tyson
8h 28m
1 stop
CHS2:13 pmCharleston
$536
United Airlines
Sep 4
CHS2:54 pmCharleston
23h 43m
1 stop
TYS2:37 pmKnoxville McGhee Tyson
Sep 7
TYS6:02 pmKnoxville McGhee Tyson
20h 48m
2 stops
CHS2:50 pmCharleston
$699

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 8/13

7:47 pm-8:36 am

1 stop12h 49m

Knoxville McGhee Tyson

Mon 8/17

6:29 pm-8:38 am

1 stop14h 09m

$216

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 8/13

7:47 pm-8:36 am

1 stop12h 49m

Knoxville McGhee Tyson

Mon 8/17

6:29 pm-8:38 am

1 stop14h 09m

$226

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 8/13

8:20 pm-8:36 am

2 stops12h 16m

Knoxville McGhee Tyson

Mon 8/17

6:29 pm-8:38 am

1 stop14h 09m

$230

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Tue 7/28

6:41 am-10:38 am

1 stop3h 57m

Knoxville McGhee Tyson

Tue 8/4

11:03 am-2:41 pm

1 stop3h 38m

$233

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 8/13

8:20 pm-8:36 am

2 stops12h 16m

Knoxville McGhee Tyson

Mon 8/17

6:29 pm-8:38 am

1 stop14h 09m

$235

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Tue 7/28

6:35 am-5:00 pm

2 stops10h 25m

Knoxville McGhee Tyson

Tue 8/4

7:00 am-12:50 pm

1 stop5h 50m

$238

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Mon 8/3

3:23 pm-11:33 pm

1 stop8h 10m

Knoxville McGhee Tyson

Wed 8/5

2:25 pm-8:38 am

1 stop18h 13m

$239
Quickest round-trip

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Sat 8/15

2:06 pm-5:34 pm

1 stop3h 28m

Knoxville McGhee Tyson

Mon 8/17

7:25 pm-11:00 pm

1 stop3h 35m

$247

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Tue 7/28

6:35 am-5:00 pm

2 stops10h 25m

Knoxville McGhee Tyson

Tue 8/4

7:00 am-7:15 pm

2 stops12h 15m

$249

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 8/13

6:11 am-9:43 am

1 stop3h 32m

Knoxville McGhee Tyson

Mon 8/17

5:15 am-9:39 am

1 stop4h 24m

$259

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Charleston to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of March is, on average, the cheapest month to fly to Knoxville from Charleston, with most prices found around $0. If you aren’t able to travel during the month of March, then book flights to Knoxville from Charleston during January instead. Flights to Knoxville in January, while not as cheap as those in March, still average around $254.

When to book flights from Charleston to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Knoxville (CHS to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Knoxville

Fastest flight time

5h 07m

Direct flights

None
The fastest flight from Charleston to Knoxville takes 5h 07m
There are no direct flights from Charleston to Knoxville. There are no popular flight routes from Charleston to Knoxville.
Search flight deals

Frequently asked questions about flying from Charleston to Knoxville

  • How far is Charleston to Knoxville McGhee Tyson by plane?

    A flight from Charleston to Knoxville McGhee Tyson will travel around 316.2 mi. Flights usually cover this in 5h 07m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Charleston Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Charleston Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Charleston Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Charleston to Knoxville?

Best airlines flying from Charleston to Knoxville

Compare and see reviews for airlines that fly from Charleston to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $254Free CancellationRating
7.8
8,452 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Knoxville?

It is quick and easy to find Charleston to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Charleston to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Charleston to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Charleston to Knoxville?

Once you have performed a search for Charleston to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 7/31
Fri 8/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States