What is the cheapest airline that flies from Charleston to Florida Keys?

Breeze Airways and Delta are the most popular carriers operating from Charleston to Florida Keys

What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from Charleston according to our data. American Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 4 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Charleston to Florida Keys on average per week?

As of September 2026, 14 flights take off from Charleston and land in Florida Keys each week. The most common flight departure day for this route is Wed, with 50% of weekly flights taking off on this day.

When did momondo last update prices for flights from Charleston Airport to Florida Keys?

Prices for flights from Charleston Airport to Florida Keys were last updated today.

How many operators does momondo search for flights from Charleston Airport to Florida Keys?

As of September 2026, there are 4 operators available to choose from for flights from Charleston Airport to Florida Keys.

How old do you have to be to fly from Charleston Airport to Florida Keys?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charleston Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$66 Cheap Flights from Charleston to Florida Keys in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 9:24 amCHS Charleston-EYW Key West

3h 24m1 stop Tampa

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

$105Breeze Airways

Wed, Sep 30 - Sat, Oct 3

6:00 am - 9:24 amCHS Charleston-EYW Key West

3h 24m1 stop Tampa

12:59 pm - 1:24 pmEYW Key West-CHS Charleston

24h 25m1 stop Tampa

$114Breeze Airways

Wed, Sep 30 - Fri, Oct 2

6:00 am - 9:24 amCHS Charleston-EYW Key West

3h 24m1 stop Tampa

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

$135Breeze Airways

Sat, Oct 31 - Wed, Nov 4

11:15 am - 6:30 pmCHS Charleston-MIA Miami

7h 15m1 stop Atlanta Hartsfield-Jackson

7:10 am - 11:35 amMIA Miami-CHS Charleston

4h 25m1 stop Atlanta Hartsfield-Jackson

$219Delta

Wed, Oct 14 - Wed, Oct 21

6:29 pm - 12:53 amCHS Charleston-MIA Miami

6h 24m1 stop Atlanta Hartsfield-Jackson

6:25 pm - 11:59 pmMIA Miami-CHS Charleston

5h 34m1 stop Atlanta Hartsfield-Jackson

$219Delta

Sat, Nov 7 - Mon, Nov 9

4:20 pm - 9:21 pmCHS Charleston-MIA Miami

5h 01m1 stop Atlanta Hartsfield-Jackson

8:10 am - 1:00 pmMIA Miami-CHS Charleston

4h 50m1 stop Atlanta Hartsfield-Jackson

$219Delta

Tue, Oct 27 - Wed, Oct 28

7:45 am - 3:25 pmCHS Charleston-MIA Miami

7h 40m1 stop Baltimore/Washington

10:05 am - 2:50 pmMIA Miami-CHS Charleston

4h 45m1 stop Nashville Intl

$246Southwest

Tue, Feb 16 - Wed, Feb 17

1:30 pm - 8:55 pmCHS Charleston-MIA Miami

7h 25m1 stop Baltimore/Washington

6:30 am - 12:45 pmMIA Miami-CHS Charleston

6h 15m1 stop Baltimore/Washington

$246Southwest

Wed, Dec 9 - Tue, Dec 15

10:57 am - 12:48 pmCHS Charleston-MIA Miami

1h 51mnonstop

10:00 pm - 11:59 pmMIA Miami-CHS Charleston

1h 59mnonstop

$337American Airlines

Sat, Feb 27 - Sat, Mar 6

7:34 pm - 9:30 pmCHS Charleston-MIA Miami

1h 56mnonstop

10:03 pm - 11:58 pmMIA Miami-CHS Charleston

1h 55mnonstop

$337American Airlines

Tue, Feb 2 - Wed, Feb 10

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Southwest flights from Charleston to Florida Keys

Our best Southwest deals on Charleston to Florida Keys flight tickets

Southwest

Dec 9

CHS1:30 pmCharleston

7h 25m

1 stop

MIA8:55 pmMiami

Dec 15

MIA6:30 amMiami

6h 15m

1 stop

CHS12:45 pmCharleston

$246

Southwest

Dec 9

CHS6:35 amCharleston

4h 45m

1 stop

MIA11:20 amMiami

Dec 15

MIA6:50 amMiami

9h 40m

2 stops

CHS4:30 pmCharleston

$252

Southwest

Dec 9

CHS1:30 pmCharleston

8h 40m

2 stops

MIA10:10 pmMiami

Dec 15

MIA11:35 amMiami

7h 55m

2 stops

CHS7:30 pmCharleston

$257

American Airlines flights from Charleston to Florida Keys

Our best American Airlines deals on Charleston to Florida Keys flight tickets

American Airlines

Oct 3

CHS6:00 amCharleston

1h 44m

MIA7:44 amMiami

Oct 7

MIA8:45 amMiami

1h 47m

CHS10:32 amCharleston

$337

American Airlines

Oct 3

CHS6:30 pmCharleston

1h 44m

MIA8:14 pmMiami

Oct 7

MIA4:17 pmMiami

5h 33m

1 stop

CHS9:50 pmCharleston

$347

American Airlines

Oct 31

CHS11:12 amCharleston

1h 43m

MIA12:55 pmMiami

Nov 7

MIA5:41 pmMiami

1h 53m

CHS7:34 pmCharleston

$356

momondo Fare Finder

Use the filters below to find and compare flights from Charleston to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Wed 9/30

6:00 am-9:24 am

1 stop3h 24m

Key West

Sat 10/3

10:04 am-1:24 pm

1 stop3h 20m

$105

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Wed 9/30

6:00 am-9:24 am

1 stop3h 24m

Key West

Fri 10/2

12:59 pm-1:24 pm

1 stop24h 25m

$114

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 10/31

6:00 am-9:24 am

1 stop3h 24m

Key West

Wed 11/4

10:04 am-1:24 pm

1 stop3h 20m

$135

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Wed 10/14

11:15 am-6:30 pm

1 stop7h 15m

Miami

Wed 10/21

7:10 am-11:35 am

1 stop4h 25m

$219

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Sat 11/7

6:29 pm-12:53 am

1 stop6h 24m

Miami

Mon 11/9

6:25 pm-11:59 pm

1 stop5h 34m

$219

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Tue 10/27

4:20 pm-9:21 pm

1 stop5h 01m

Miami

Wed 10/28

8:10 am-1:00 pm

1 stop4h 50m

$219

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Tue 2/16

7:45 am-3:25 pm

1 stop7h 40m

Miami

Wed 2/17

10:05 am-2:50 pm

1 stop4h 45m

$246

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Wed 12/9

1:30 pm-8:55 pm

1 stop7h 25m

Miami

Tue 12/15

6:30 am-12:45 pm

1 stop6h 15m

$246

Quickest round-trip

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Sat 2/27

10:57 am-12:48 pm

Nonstop1h 51m

Miami

Sat 3/6

10:00 pm-11:59 pm

Nonstop1h 59m

$337

CharlestonMiami

CHS Charleston - MIA Miami

CHSMIA

Charleston

Tue 2/2

7:34 pm-9:30 pm

Nonstop1h 56m

Miami

Wed 2/10

10:03 pm-11:58 pm

Nonstop1h 55m

$337

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charleston to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Charleston averaging around $296.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Charleston to Florida Keys is on a Friday when prices can be found for as low as $529. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $616.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Charleston to Florida Keys in the afternoon for as low as $287. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $578.

How far in advance should I book a flight from Charleston to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Charleston when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $336 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Charleston for as low as $273 on momondo.

Can stopping save me money on Charleston to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Charleston to Florida Keys.

Cheap Charleston to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Florida Keys

Best Price Found	$66
Fastest flight time	1h 40m
Direct flights	Every day
Airports in Florida Keys	3 airports

The best one-way flight to Florida Keys from Charleston in the past 72 hours is $66. The best round-trip flight deal from Charleston to Florida Keys found on momondo in the last 72 hours is $105.

The fastest flight from Charleston to Florida Keys takes 1h 40m

Direct flights go from Charleston to Florida Keys every day.

There are 3 airports in Florida Keys. From Charleston there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from Charleston to Florida Keys

When did momondo last update prices for flights from Charleston Airport to Florida Keys?
Prices for flights from Charleston Airport to Florida Keys were last updated today.
How many operators does momondo search for flights from Charleston Airport to Florida Keys?
As of September 2026, there are 4 operators available to choose from for flights from Charleston Airport to Florida Keys.
How old do you have to be to fly from Charleston Airport to Florida Keys?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charleston Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Charleston to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Charleston to Florida Keys is Airbus A220-300, representing 26.76% of all bookings. The subsequent popular models are Canadair (Bombardier) Regional Jet 900 at 10.34%, Airbus A320-100/200 at 9.55%, and Embraer 175 at 7.57%.

Best airlines flying from Charleston to Florida Keys

Compare and see reviews for airlines that fly from Charleston to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $104	Free Cancellation	Rating 8.2 324 reviews	Search Breeze Airways flights
American Airlines	PriceFrom $327	Free Cancellation	Rating 7.1 12,077 reviews	Search American Airlines flights
Delta	PriceFrom $344	Free Cancellation	Rating 7.8 8,586 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Florida Keys?

It is quick and easy to find Charleston to Florida Keys flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florida Keys that suits you.

Can I find flights from Charleston to Florida Keys with flexible booking policies on momondo?

Flights from Charleston to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Florida Keys?

momondo helps you find the best flight between Charleston and Florida Keys by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charleston to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.