What is the cheapest airline that flies from Charleston to Des Moines?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Charleston to Des Moines

When did momondo last update prices for flights from Charleston Airport to Des Moines Airport?

Prices for flights from Charleston Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Charleston Airport to Des Moines Airport?

The number of operators available for flights from Charleston Airport to Des Moines Airport is 2 as of July 2025.

How old do you have to be to fly from Charleston Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$119 Cheap Flights from Charleston to Des Moines in 2025

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Find the cheapest flights from Charleston to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

5:33 pm - 10:58 pmCHS-DSM

6h 25m1 stop

6:12 pm - 11:57 pmDSM-CHS

4h 45m1 stop

$427American Airlines

Find Deal

mié., ago. 13 - dom., ago. 17

6:00 am - 12:39 pmCHS-DSM

7h 39m2 stops

7:00 am - 12:16 pmDSM-CHS

4h 16m1 stop

$432American Airlines

Find Deal

mié., ago. 13 - dom., ago. 17

8:16 pm - 11:27 pmCHS-DSM

28h 11m3 stops

7:15 pm - 7:12 pmDSM-CHS

22h 57m2 stops

$533

Find Deal

mié., ago. 13 - dom., ago. 17

8:16 pm - 11:27 pmCHS-DSM

28h 11m3 stops

7:15 pm - 7:12 pmDSM-CHS

22h 57m3 stops

$614

Find Deal

mié., ago. 13 - dom., ago. 17

1:00 pm - 8:30 pmCHS-DSM

8h 30m2 stops

2:49 pm - 11:51 pmDSM-CHS

8h 02m2 stops

$718Delta

Find Deal

mié., ago. 13 - dom., ago. 17

6:05 am - 10:32 amCHS-DSM

5h 27m1 stop

1:10 pm - 7:08 pmDSM-CHS

4h 58m1 stop

$782United Airlines

Find Deal

dom., ago. 17 - vie., ago. 29

American Airlines flights from Charleston to Des Moines

Our best American Airlines deals on Charleston to Des Moines flight tickets

American Airlines

Aug 13

CHS5:33 pmCharleston

6h 25m

1 stop

DSM10:58 pmDes Moines

Aug 17

DSM6:12 pmDes Moines

4h 45m

1 stop

CHS11:57 pmCharleston

$427

Find similar

American Airlines

Aug 13

CHS6:00 amCharleston

7h 39m

2 stops

DSM12:39 pmDes Moines

Aug 17

DSM7:00 amDes Moines

4h 16m

1 stop

CHS12:16 pmCharleston

$432

Find similar

American Airlines

Aug 4

CHS4:13 pmCharleston

6h 53m

1 stop

DSM10:06 pmDes Moines

Aug 7

DSM12:44 pmDes Moines

7h 41m

1 stop

CHS9:25 pmCharleston

$647

Find similar

United Airlines flights from Charleston to Des Moines

Our best United Airlines deals on Charleston to Des Moines flight tickets

United Airlines

Aug 17

CHS6:05 amCharleston

5h 27m

1 stop

DSM10:32 amDes Moines

Aug 29

DSM1:10 pmDes Moines

4h 58m

1 stop

CHS7:08 pmCharleston

$782

Find similar

United Airlines

Aug 7

CHS6:05 amCharleston

5h 24m

1 stop

DSM10:29 amDes Moines

Aug 10

DSM8:00 amDes Moines

5h 02m

1 stop

CHS2:02 pmCharleston

$982

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/13

5:33 pm-10:58 pm

1 stop6h 25m

Des Moines

dom. 8/17

6:12 pm-11:57 pm

1 stop4h 45m

$427

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/13

6:00 am-12:39 pm

2 stops7h 39m

Des Moines

dom. 8/17

7:00 am-12:16 pm

1 stop4h 16m

$432

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/13

8:16 pm-11:27 pm

3 stops28h 11m

Des Moines

dom. 8/17

7:15 pm-7:12 pm

2 stops22h 57m

$533

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/13

8:16 pm-11:27 pm

3 stops28h 11m

Des Moines

dom. 8/17

7:15 pm-7:12 pm

3 stops22h 57m

$614

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/13

1:00 pm-8:30 pm

2 stops8h 30m

Des Moines

dom. 8/17

2:49 pm-11:51 pm

2 stops8h 02m

$718

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

dom. 8/17

6:05 am-10:32 am

1 stop5h 27m

Des Moines

vie. 8/29

1:10 pm-7:08 pm

1 stop4h 58m

$782

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 10/7

7:30 am-1:18 pm

1 stop6h 48m

$119

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 10/7

6:30 am-1:18 pm

2 stops7h 48m

$124

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

dom. 10/19

6:40 am-10:05 am

1 stop4h 25m

$170

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

dom. 9/28

5:10 am-2:03 pm

2 stops9h 53m

$175

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charleston to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in May, then April is your next best option. Flight prices from Charleston to Des Moines during April average around $357.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Charleston to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $321. Flights from Charleston to Des Moines on a Saturday will generally be more expensive and average around $594. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Charleston to Des Moines in the afternoon for as low as $411. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $485. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Charleston to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Charleston to Des Moines (CHS to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Des Moines

Best Price Found	$119
Fastest flight time	4h 25m
Direct flights	None
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Charleston in the past 72 hours is $119. The best round-trip flight deal from Charleston to Des Moines found on momondo in the last 72 hours is $427.

The fastest flight from Charleston to Des Moines takes 4h 25m

There are no direct flights from Charleston to Des Moines. Popular non-direct route for this connection is Charleston Airport - Des Moines Airport.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Charleston to Des Moines by plane?
There are 966.2 mi between Charleston and Des Moines. 5h 27m is a normal flight duration for this route.
When did momondo last update prices for flights from Charleston Airport to Des Moines Airport?
Prices for flights from Charleston Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Charleston Airport to Des Moines Airport?
The number of operators available for flights from Charleston Airport to Des Moines Airport is 2 as of July 2025.
How old do you have to be to fly from Charleston Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Charleston to Des Moines?
Based on momondo bookings for flights between Charleston and Des Moines, the leading airline is Delta, making up 53% of the total bookings. Other popular airlines include American Airlines with 47%.

Best airlines flying from Charleston to Des Moines

Compare and see reviews for airlines that fly from Charleston to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 8.0 7,981 reviews		Search Delta flights
American Airlines	PriceFrom $270	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

West Des Moines

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Osceola

Norwalk

Grinnell

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Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Des Moines?

Finding the right flight to Des Moines from Charleston is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Charleston to Des Moines with flexible booking policies on momondo?

Flights from Charleston to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charleston to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.