What airlines fly to South Carolina?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to South Carolina from Central America according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Central America to South Carolina on average per week?

6 flights are operational weekly from Central America to South Carolina as of February 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.

What is the cheapest airline that flies from Central America to South Carolina?

Spirit Airlines, American Airlines, and Copa Airlines are the most popular carriers operating from Central America to South Carolina

When did momondo last update prices for flights from Central America to South Carolina?

Prices for flights from Central America to South Carolina were last updated today.

How many operators does momondo search for flights from Central America to South Carolina?

The number of operators available for flights from Central America to South Carolina is 4 as of February 2026.

How old do you have to be to fly from Central America to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Central America to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$131 Cheap Flights from Central America to South Carolina in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Central America to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:15 pm - 10:33 pm

GUA

CLT

8h 18m

1 stop

9:24 pm - 11:20 am

CLT

GUA

15h 56m

1 stop

$236Spirit Airlines

vie., abr. 24 - dom., may. 17

12:15 pm - 10:33 pm

GUA

CLT

8h 18m

1 stop

6:00 am - 11:20 am

CLT

GUA

7h 20m

1 stop

$252Spirit Airlines

jue., abr. 23 - sáb., may. 9

12:15 pm - 10:33 pm

GUA

CLT

8h 18m

1 stop

6:00 am - 11:20 am

CLT

GUA

7h 20m

1 stop

$254Spirit Airlines

vie., abr. 24 - mié., may. 20

6:38 pm - 12:25 am

GUA

CLT

27h 47m

1 stop

9:24 pm - 11:20 am

CLT

GUA

15h 56m

1 stop

$259Multiple Airlines

mar., abr. 7 - jue., abr. 16

1:52 pm - 2:17 pm

SAP

CLT

22h 25m

1 stop

1:59 pm - 10:04 am

CLT

SAP

22h 05m

1 stop

$268Multiple Airlines

mar., mar. 24 - mar., mar. 31

3:20 pm - 7:09 am

PTY

CLT

14h 49m

1 stop

10:25 pm - 2:20 pm

CLT

PTY

16h 55m

1 stop

$421American Airlines

vie., ago. 21 - lun., ago. 24

9:00 am - 10:10 am

SJO

SAV

23h 10m

2 stops

6:40 am - 7:00 pm

SAV

SJO

14h 20m

2 stops

$437Southwest

vie., may. 1 - mar., may. 5

1:49 pm - 10:00 am

PTY

CLT

19h 11m

1 stop

8:45 pm - 12:46 pm

CLT

PTY

17h 01m

1 stop

$451American Airlines

mié., abr. 15 - dom., abr. 19

2:27 pm - 11:53 pm

PTY

CLT

8h 26m

1 stop

6:46 am - 1:02 pm

CLT

PTY

7h 16m

1 stop

$465Delta

vie., abr. 17 - dom., abr. 19

1:20 pm - 11:54 pm

SJO

GSP

8h 34m

1 stop

8:30 am - 9:15 pm

GSP

SJO

14h 45m

1 stop

$567Delta

mar., mar. 17 - mar., mar. 24

Spirit Airlines flights from Central America to South Carolina

Our best Spirit Airlines deals on Central America to South Carolina flight tickets

Spirit Airlines

Apr 24

GUA12:15 pmGuatemala City La Aurora

8h 18m

1 stop

CLT10:33 pmCharlotte Douglas

May 17

CLT9:24 pmCharlotte Douglas

15h 56m

1 stop

GUA11:20 amGuatemala City La Aurora

$236

Spirit Airlines

Apr 23

GUA12:15 pmGuatemala City La Aurora

8h 18m

1 stop

CLT10:33 pmCharlotte Douglas

May 9

CLT6:00 amCharlotte Douglas

7h 20m

1 stop

GUA11:20 amGuatemala City La Aurora

$252

Spirit Airlines

Apr 24

GUA12:15 pmGuatemala City La Aurora

8h 18m

1 stop

CLT10:33 pmCharlotte Douglas

May 20

CLT6:00 amCharlotte Douglas

7h 20m

1 stop

GUA11:20 amGuatemala City La Aurora

$254

Delta flights from Central America to South Carolina

Our best Delta deals on Central America to South Carolina flight tickets

Delta

May 21

GUA12:56 pmGuatemala City La Aurora

7h 03m

1 stop

CLT9:59 pmCharlotte Douglas

Sep 22

CLT8:00 amCharlotte Douglas

5h 30m

1 stop

GUA11:30 amGuatemala City La Aurora

$423

Delta

Apr 17

PTY2:27 pmPanama City Tocumen Intl

8h 26m

1 stop

CLT11:53 pmCharlotte Douglas

Apr 19

CLT6:46 amCharlotte Douglas

7h 16m

1 stop

PTY1:02 pmPanama City Tocumen Intl

$465

Delta

Mar 16

SJO1:20 pmSan José Juan Santamaria Intl

6h 32m

1 stop

GSP9:52 pmGreenville

Mar 23

GSP11:56 amGreenville

11h 19m

1 stop

SJO9:15 pmSan José Juan Santamaria Intl

$586

momondo Fare Finder

Use the filters below to find and compare flights from Central America to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

vie. 4/24

12:15 pm-10:33 pm

1 stop8h 18m

Charlotte Douglas

dom. 5/17

9:24 pm-11:20 am

1 stop15h 56m

$236

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

jue. 4/23

12:15 pm-10:33 pm

1 stop8h 18m

Charlotte Douglas

sáb. 5/9

6:00 am-11:20 am

1 stop7h 20m

$252

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

vie. 4/24

12:15 pm-10:33 pm

1 stop8h 18m

Charlotte Douglas

mié. 5/20

6:00 am-11:20 am

1 stop7h 20m

$254

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

mar. 4/7

6:38 pm-12:25 am

1 stop27h 47m

Charlotte Douglas

jue. 4/16

9:24 pm-11:20 am

1 stop15h 56m

$259

San Pedro SulaCharlotte

SAP - CLT

SAPCLT

San Pedro Sula Ramon Villeda

mar. 3/24

1:52 pm-2:17 pm

1 stop22h 25m

Charlotte Douglas

mar. 3/31

1:59 pm-10:04 am

1 stop22h 05m

$268

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

vie. 8/21

3:20 pm-7:09 am

1 stop14h 49m

Charlotte Douglas

lun. 8/24

10:25 pm-2:20 pm

1 stop16h 55m

$421

San JoséSavannah

SJO - SAV

SJOSAV

San José Juan Santamaria Intl

vie. 5/1

9:00 am-10:10 am

2 stops23h 10m

Savannah/Hilton Head

mar. 5/5

6:40 am-7:00 pm

2 stops14h 20m

$437

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mié. 4/15

1:49 pm-10:00 am

1 stop19h 11m

Charlotte Douglas

dom. 4/19

8:45 pm-12:46 pm

1 stop17h 01m

$451

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

vie. 4/17

2:27 pm-11:53 pm

1 stop8h 26m

Charlotte Douglas

dom. 4/19

6:46 am-1:02 pm

1 stop7h 16m

$465

San JoséGreenville

SJO - GSP

SJOGSP

San José Juan Santamaria Intl

mar. 3/17

1:20 pm-11:54 pm

1 stop8h 34m

Greenville

mar. 3/24

8:30 am-9:15 pm

1 stop14h 45m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Central America to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Central America is in February. Flight prices, which tend to average around $286, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to South Carolina from Central America during April instead. Flights to South Carolina in April, while not as cheap as those in February, still average around $339.

Can stopping save me money on Central America to South Carolina flights?

You could potentially save up to 39% on your flight if you consider stops on a Central America to South Carolina flight.

Cheap Central America to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Central America to South Carolina

Fastest flight time	4h 20m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Central America to South Carolina takes 4h 20m

Direct flights go from Central America to South Carolina every day.

There are 57 airports in South Carolina. From Central America there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Central America to South Carolina?
Prices for flights from Central America to South Carolina were last updated today.
How many operators does momondo search for flights from Central America to South Carolina?
The number of operators available for flights from Central America to South Carolina is 4 as of February 2026.
How old do you have to be to fly from Central America to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Central America to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Central America to South Carolina

Compare and see reviews for airlines that fly from Central America to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $249	Free Cancellation	Rating 6.3 8,494 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $252	Free Cancellation	Rating 7.2 11,352 reviews	Search American Airlines flights
Delta	PriceFrom $286	Free Cancellation	Rating 7.9 8,237 reviews	Search Delta flights
United Airlines	PriceFrom $310	Free Cancellation	Rating 7.4 9,348 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Central America to South Carolina?

Finding the right flight to South Carolina from Central America is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from Central America to South Carolina with flexible booking policies on momondo?

Flights from Central America to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Central America to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Central America.

I’m not ready to book a flight from Central America to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Central America to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.