Cheap flights from Central America to South Carolina from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Central America to South Carolina departing on 5/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Central America to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
3:47 pm - 11:34 am
GUA
-
CLT
17h 47m
1 stop
Frontier Logo
1:12 pm - 2:42 pm
CLT
-
GUA
27h 30m
1 stop
$307Frontier
Tue, Jun 30 - Wed, Jul 15
Spirit Airlines Logo
1:00 pm - 11:34 am
SJO
-
CLT
20h 34m
1 stop
Spirit Airlines Logo
9:07 pm - 11:45 am
CLT
-
SJO
16h 38m
1 stop
$312Spirit Airlines
Fri, May 8 - Thu, May 14
Multiple Airlines Logo
1:00 pm - 11:40 pm
SJO
-
CLT
8h 40m
1 stop
Multiple Airlines Logo
6:33 pm - 11:45 am
CLT
-
SJO
19h 12m
1 stop
$314Multiple Airlines
Fri, May 15 - Sun, Jun 14
Multiple Airlines Logo
9:35 am - 6:52 pm
SJO
-
CLT
7h 17m
1 stop
Multiple Airlines Logo
8:34 pm - 8:20 am
CLT
-
SJO
13h 46m
1 stop
$330Multiple Airlines
Thu, Jun 4 - Fri, Jun 19
American Airlines Logo
2:40 pm - 11:59 pm
LIR
-
CLT
31h 19m
1 stop
American Airlines Logo
9:17 am - 11:28 am
CLT
-
LIR
4h 11mnonstop
$509American Airlines
Fri, May 8 - Sun, May 10
American Airlines Logo
2:40 pm - 11:59 pm
LIR
-
CLT
31h 19m
1 stop
American Airlines Logo
9:17 am - 11:28 am
CLT
-
LIR
4h 11mnonstop
$510American Airlines
Fri, May 8 - Sun, May 10
Delta Logo
2:15 pm - 11:53 pm
PTY
-
CLT
8h 38m
1 stop
Delta Logo
5:30 am - 1:09 pm
CLT
-
PTY
8h 39m
1 stop
$562Delta
Mon, Jun 1 - Mon, Jun 8
Delta Logo
12:35 pm - 11:43 pm
SAP
-
GSP
9h 08m
1 stop
Delta Logo
5:40 am - 11:10 am
GSP
-
SAP
7h 30m
1 stop
$615Delta
Wed, May 13 - Tue, May 19
United Airlines Logo
3:27 pm - 10:56 am
LIR
-
CLT
17h 29m
1 stop
United Airlines Logo
6:35 am - 2:25 pm
CLT
-
LIR
9h 50m
1 stop
$618United Airlines
Thu, May 14 - Mon, May 18
United Airlines Logo
1:20 pm - 10:45 am
LIR
-
CLT
19h 25m
2 stops
United Airlines Logo
6:35 am - 12:10 pm
CLT
-
LIR
7h 35m
1 stop
$623United Airlines
Thu, May 14 - Mon, May 18

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Frontier flights from Central America to South Carolina

Our best Frontier deals on Central America to South Carolina flight tickets
Frontier
Jun 30
GUA3:47 pmGuatemala City La Aurora
17h 47m
1 stop
CLT11:34 amCharlotte Douglas
Jul 15
CLT1:12 pmCharlotte Douglas
27h 30m
1 stop
GUA2:42 pmGuatemala City La Aurora
$307
Frontier
Jun 1
SJO9:35 amSan José Juan Santamaria Intl
29h 08m
1 stop
CLT4:43 pmCharlotte Douglas
Jun 19
CLT7:58 pmCharlotte Douglas
14h 22m
1 stop
SJO8:20 amSan José Juan Santamaria Intl
$328
Frontier
Jun 9
SAP9:30 amSan Pedro Sula Ramon Villeda
24h 04m
1 stop
CLT11:34 amCharlotte Douglas
Jun 15
CLT7:58 pmCharlotte Douglas
14h 27m
1 stop
SAP8:25 amSan Pedro Sula Ramon Villeda
$340

Spirit Airlines flights from Central America to South Carolina

Our best Spirit Airlines deals on Central America to South Carolina flight tickets
Spirit Airlines
May 8
SJO1:00 pmSan José Juan Santamaria Intl
20h 34m
1 stop
CLT11:34 amCharlotte Douglas
May 14
CLT9:07 pmCharlotte Douglas
16h 38m
1 stop
SJO11:45 amSan José Juan Santamaria Intl
$312
Spirit Airlines
May 7
GUA12:17 pmGuatemala City La Aurora
9h 23m
1 stop
CLT11:40 pmCharlotte Douglas
Jun 2
CLT7:57 pmCharlotte Douglas
16h 26m
1 stop
GUA10:23 amGuatemala City La Aurora
$332
Spirit Airlines
May 7
GUA12:17 pmGuatemala City La Aurora
9h 23m
1 stop
CLT11:40 pmCharlotte Douglas
Jun 2
CLT3:16 pmCharlotte Douglas
21h 07m
2 stops
GUA10:23 amGuatemala City La Aurora
$337

momondo Fare Finder

 
Customize your flight search to find flights from Central America to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 20, 2026.
Use the filters below to find and compare flights from Central America to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

Tue 6/30

3:47 pm-11:34 am

1 stop17h 47m

Charlotte Douglas

Wed 7/15

1:12 pm-2:42 pm

1 stop27h 30m

$307

San JoséCharlotte

SJO - CLT

SJOCLT

San José Juan Santamaria Intl

Fri 5/8

1:00 pm-11:34 am

1 stop20h 34m

Charlotte Douglas

Thu 5/14

9:07 pm-11:45 am

1 stop16h 38m

$312

San JoséCharlotte

SJO - CLT

SJOCLT

San José Juan Santamaria Intl

Fri 5/15

1:00 pm-11:40 pm

1 stop8h 40m

Charlotte Douglas

Sun 6/14

6:33 pm-11:45 am

1 stop19h 12m

$314

San JoséCharlotte

SJO - CLT

SJOCLT

San José Juan Santamaria Intl

Thu 6/4

9:35 am-6:52 pm

1 stop7h 17m

Charlotte Douglas

Fri 6/19

8:34 pm-8:20 am

1 stop13h 46m

$330

LiberiaCharlotte

LIR - CLT

LIRCLT

Liberia

Fri 5/8

2:40 pm-11:59 pm

1 stop31h 19m

Charlotte Douglas

Sun 5/10

9:17 am-11:28 am

Nonstop4h 11m

$509

LiberiaCharlotte

LIR - CLT

LIRCLT

Liberia

Fri 5/8

2:40 pm-11:59 pm

1 stop31h 19m

Charlotte Douglas

Sun 5/10

9:17 am-11:28 am

Nonstop4h 11m

$510

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 6/1

2:15 pm-11:53 pm

1 stop8h 38m

Charlotte Douglas

Mon 6/8

5:30 am-1:09 pm

1 stop8h 39m

$562
Quickest round-trip

San Pedro SulaGreenville

SAP - GSP

SAPGSP

San Pedro Sula Ramon Villeda

Wed 5/13

12:35 pm-11:43 pm

1 stop9h 08m

Greenville

Tue 5/19

5:40 am-11:10 am

1 stop7h 30m

$615

LiberiaCharlotte

LIR - CLT

LIRCLT

Liberia

Thu 5/14

3:27 pm-10:56 am

1 stop17h 29m

Charlotte Douglas

Mon 5/18

6:35 am-2:25 pm

1 stop9h 50m

$618

LiberiaCharlotte

LIR - CLT

LIRCLT

Liberia

Thu 5/14

1:20 pm-10:45 am

2 stops19h 25m

Charlotte Douglas

Mon 5/18

6:35 am-12:10 pm

1 stop7h 35m

$623

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Central America to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Central America is in April. Flight prices, which tend to average around $311, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of April, then book flights to South Carolina from Central America during September instead. Flights to South Carolina in September, while not as cheap as those in April, still average around $371.

Can stopping save me money on Central America to South Carolina flights?

You could potentially save up to 24% on your flight if you consider stops on a Central America to South Carolina flight.

Cheap Central America to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Central America to South Carolina

Fastest flight time

4h 33m

Direct flights

Every day

Airports in South Carolina

57 airports
The fastest flight from Central America to South Carolina takes 4h 33m
Direct flights go from Central America to South Carolina every day.
There are 57 airports in South Carolina. From Central America there are direct flights to Charlotte Douglas (CLT).

Frequently asked questions about flying from Central America to South Carolina

  • When did momondo last update prices for flights from Central America to South Carolina?

    Prices for flights from Central America to South Carolina were last updated today.

  • How many operators does momondo search for flights from Central America to South Carolina?

  • How old do you have to be to fly from Central America to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Central America to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Central America to South Carolina

Compare and see reviews for airlines that fly from Central America to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $249Free CancellationRating
6.3
8,626 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $252Free CancellationRating
7.1
11,629 reviews
Search American Airlines flights
DeltaPriceFrom $298Free CancellationRating
7.9
8,424 reviews
Search Delta flights
United AirlinesPriceFrom $310Free CancellationRating
7.4
9,608 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Central America to South Carolina?

Finding the right flight to South Carolina from Central America is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.

Can I find flights from Central America to South Carolina with flexible booking policies on momondo?

Flights from Central America to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Central America to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Central America.

I’m not ready to book a flight from Central America to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Central America to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

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1 adult
Wed 5/20
Wed 5/27

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