Cheap flights from Central America to Panama City from $268

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Central America to Panama City departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:00 am - 4:15 pm
SJO
-
ECP
9h 15m1 stop
Delta Logo
2:05 pm - 10:02 pm
ECP
-
SJO
7h 57m1 stop
$388Delta
Tue, Feb 17 - Sun, Feb 22
Delta Logo
7:00 am - 4:15 pm
SJO
-
ECP
9h 15m1 stop
Delta Logo
6:00 am - 10:02 pm
ECP
-
SJO
16h 02m1 stop
$457Delta
Tue, Feb 17 - Thu, Feb 19
Delta Logo
7:00 am - 5:58 pm
SJO
-
ECP
9h 58m1 stop
Delta Logo
8:25 am - 9:15 pm
ECP
-
SJO
13h 50m1 stop
$477Delta
Tue, Mar 10 - Tue, Mar 17
Delta Logo
7:00 am - 10:40 pm
SJO
-
ECP
15h 40m1 stop
Delta Logo
7:20 am - 2:29 pm
ECP
-
SJO
7h 09m1 stop
$502Delta
Tue, Jan 27 - Sat, Jan 31
Delta Logo
7:00 am - 7:30 pm
SJO
-
ECP
12h 30m1 stop
Delta Logo
6:00 am - 10:02 pm
ECP
-
SJO
16h 02m1 stop
$527Delta
Mon, Feb 16 - Thu, Feb 19
American Airlines Logo
2:10 pm - 9:37 am
SJO
-
ECP
19h 27m1 stop
American Airlines Logo
12:40 pm - 9:43 pm
ECP
-
SJO
10h 03m1 stop
$540American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
2:10 pm - 10:37 pm
SJO
-
ECP
8h 27m1 stop
American Airlines Logo
6:42 am - 9:43 pm
ECP
-
SJO
16h 01m1 stop
$541American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
1:25 pm - 9:37 am
SJO
-
ECP
20h 12m2 stops
American Airlines Logo
12:40 pm - 9:43 pm
ECP
-
SJO
10h 03m1 stop
$545American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
3:55 pm - 1:14 pm
SJO
-
ECP
21h 19m2 stops
American Airlines Logo
10:20 am - 7:55 pm
ECP
-
SJO
10h 35m2 stops
$546American Airlines
Tue, Mar 3 - Tue, Mar 10
United Airlines Logo
12:30 am - 4:17 pm
SJO
-
ECP
14h 47m1 stop
United Airlines Logo
9:00 am - 10:39 pm
ECP
-
SJO
14h 39m1 stop
$555United Airlines
Thu, May 28 - Fri, Jun 5

Delta flights from Central America to Panama City, Florida

Our best Delta deals on Central America to Panama City, Florida flight tickets
Delta
Feb 17
SJO7:00 amSan José Juan Santamaria Intl
9h 15m
1 stop
ECP4:15 pmPanama City NW Florida Beaches
Feb 22
ECP2:05 pmPanama City NW Florida Beaches
7h 57m
1 stop
SJO10:02 pmSan José Juan Santamaria Intl
Delta
Feb 17
SJO7:00 amSan José Juan Santamaria Intl
9h 15m
1 stop
ECP4:15 pmPanama City NW Florida Beaches
Feb 20
ECP12:10 pmPanama City NW Florida Beaches
9h 52m
1 stop
SJO10:02 pmSan José Juan Santamaria Intl
Delta
Mar 10
SJO7:00 amSan José Juan Santamaria Intl
9h 58m
1 stop
ECP5:58 pmPanama City NW Florida Beaches
Mar 17
ECP8:25 amPanama City NW Florida Beaches
13h 50m
1 stop
SJO9:15 pmSan José Juan Santamaria Intl

American Airlines flights from Central America to Panama City, Florida

Our best American Airlines deals on Central America to Panama City, Florida flight tickets
American Airlines
Mar 3
SJO2:10 pmSan José Juan Santamaria Intl
19h 27m
1 stop
ECP9:37 amPanama City NW Florida Beaches
Mar 10
ECP12:40 pmPanama City NW Florida Beaches
10h 03m
1 stop
SJO9:43 pmSan José Juan Santamaria Intl
American Airlines
Mar 3
SJO2:10 pmSan José Juan Santamaria Intl
8h 27m
1 stop
ECP10:37 pmPanama City NW Florida Beaches
Mar 10
ECP6:42 amPanama City NW Florida Beaches
16h 01m
1 stop
SJO9:43 pmSan José Juan Santamaria Intl
American Airlines
Mar 3
SJO1:25 pmSan José Juan Santamaria Intl
20h 12m
2 stops
ECP9:37 amPanama City NW Florida Beaches
Mar 10
ECP12:40 pmPanama City NW Florida Beaches
10h 03m
1 stop
SJO9:43 pmSan José Juan Santamaria Intl

momondo Fare Finder

 
Customize your flight search to find flights from Central America to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Central America to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 2/17

7:00 am-4:15 pm

1 stop9h 15m

Panama City NW Florida Beaches

Sun 2/22

2:05 pm-10:02 pm

1 stop7h 57m

$388

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 2/17

7:00 am-4:15 pm

1 stop9h 15m

Panama City NW Florida Beaches

Thu 2/19

6:00 am-10:02 pm

1 stop16h 02m

$457

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/10

7:00 am-5:58 pm

1 stop9h 58m

Panama City NW Florida Beaches

Tue 3/17

8:25 am-9:15 pm

1 stop13h 50m

$477

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 1/27

7:00 am-10:40 pm

1 stop15h 40m

Panama City NW Florida Beaches

Sat 1/31

7:20 am-2:29 pm

1 stop7h 09m

$502

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Mon 2/16

7:00 am-7:30 pm

1 stop12h 30m

Panama City NW Florida Beaches

Thu 2/19

6:00 am-10:02 pm

1 stop16h 02m

$527

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/3

2:10 pm-9:37 am

1 stop19h 27m

Panama City NW Florida Beaches

Tue 3/10

12:40 pm-9:43 pm

1 stop10h 03m

$540

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/3

2:10 pm-10:37 pm

1 stop8h 27m

Panama City NW Florida Beaches

Tue 3/10

6:42 am-9:43 pm

1 stop16h 01m

$541

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/3

1:25 pm-9:37 am

2 stops20h 12m

Panama City NW Florida Beaches

Tue 3/10

12:40 pm-9:43 pm

1 stop10h 03m

$545

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/3

3:55 pm-1:14 pm

2 stops21h 19m

Panama City NW Florida Beaches

Tue 3/10

10:20 am-7:55 pm

2 stops10h 35m

$546

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Thu 5/28

12:30 am-4:17 pm

1 stop14h 47m

Panama City NW Florida Beaches

Fri 6/5

9:00 am-10:39 pm

1 stop14h 39m

$555

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Central America to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $445. On the other hand, Friday is the most expensive day to depart from Central America because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $657.

Can stopping save me money on Central America to Panama City, Florida flights?

You could potentially save up to 32% on your flight if you consider stops on a Central America to Panama City, Florida flight.

Cheap Central America to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Central America to Panama City, Florida

Fastest flight time

7h 25m

Direct flights

None
The fastest flight from Central America to Panama City, Florida takes 7h 25m
There are no direct flights from Central America to Panama City, Florida. There are no popular flight routes from Central America to Panama City, Florida.
  • When did momondo last update prices for flights from Central America to Panama City NW Florida Beaches Airport?

    Prices for flights from Central America to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Central America to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Central America to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Central America to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Central America to Panama City, Florida

Compare and see reviews for airlines that fly from Central America to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $458Free CancellationRating
7.4
9,111 reviews
Search United Airlines flights
American AirlinesPriceFrom $510Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Central America to Panama City?

Finding the right flight to Panama City from Central America is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Central America to Panama City with flexible booking policies on momondo?

All flight searches from Central America to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Central America to Panama City?

momondo helps you find the best flight between Central America and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Central America to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Central America and alert you when they change.

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1 adult
Thu 1/22
Thu 1/29

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