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Cheap flights from the Cayman Islands to Buffalo from $258

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the Cayman Islands to Buffalo departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from the Cayman Islands to Buffalo

Recent round-trip flight deals from the Cayman Islands to Buffalo

Enter your travel dates to find the best prices.
American Airlines Logo
11:55 am - 11:39 amGCM  George Town Owen Roberts Intl-BUF Buffalo
22h 44m2 stops Miami Chicago O'Hare Intl
American Airlines Logo
6:56 pm - 11:30 amBUF  Buffalo-GCM George Town Owen Roberts Intl
17h 34m2 stops Chicago O'Hare Intl Charlotte Douglas
$362American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
11:55 am - 10:18 amGCM  George Town Owen Roberts Intl-BUF Buffalo
21h 23m2 stops Miami Philadelphia
American Airlines Logo
6:30 am - 11:27 amBUF  Buffalo-GCM George Town Owen Roberts Intl
5h 57m1 stop Charlotte Douglas
$362American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
12:36 pm - 9:47 pmGCM  George Town Owen Roberts Intl-BUF Buffalo
8h 11m1 stop Charlotte Douglas
American Airlines Logo
6:30 am - 11:27 amBUF  Buffalo-GCM George Town Owen Roberts Intl
5h 57m1 stop Charlotte Douglas
$521American Airlines
Sat, Sep 26 - Sat, Oct 3
United Airlines Logo
1:35 pm - 9:29 amGCM  George Town Owen Roberts Intl-BUF Buffalo
18h 54m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
7:59 pm - 12:30 pmBUF  Buffalo-GCM George Town Owen Roberts Intl
17h 31m3 stops Washington, D.C. Dulles Intl Raleigh-Durham Houston George Bush Intcntl
$4,800United Airlines
Sat, Sep 26 - Sat, Oct 3

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American Airlines flights from Cayman Islands to Buffalo

Our best American Airlines deals on Cayman Islands to Buffalo flight tickets
American Airlines
Sep 26
GCM11:55 amGeorge Town Owen Roberts Intl
22h 44m
2 stops
BUF11:39 amBuffalo
Oct 3
BUF6:56 pmBuffalo
17h 34m
2 stops
GCM11:30 amGeorge Town Owen Roberts Intl
$362
American Airlines
Sep 26
GCM12:36 pmGeorge Town Owen Roberts Intl
8h 11m
1 stop
BUF9:47 pmBuffalo
Oct 3
BUF6:30 amBuffalo
5h 57m
1 stop
GCM11:27 amGeorge Town Owen Roberts Intl
$521

momondo Fare Finder

 
Customize your flight search to find flights from Cayman Islands to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from the Cayman Islands to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 9/26

11:55 am-11:39 am

2 stops22h 44m

Buffalo

Sat 10/3

6:56 pm-11:30 am

2 stops17h 34m

$362

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 9/26

11:55 am-10:18 am

2 stops21h 23m

Buffalo

Sat 10/3

6:30 am-11:27 am

1 stop5h 57m

$362
Quickest round-trip

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 9/26

12:36 pm-9:47 pm

1 stop8h 11m

Buffalo

Sat 10/3

6:30 am-11:27 am

1 stop5h 57m

$521

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 9/26

1:35 pm-9:29 am

2 stops18h 54m

Buffalo

Sat 10/3

7:59 pm-12:30 pm

3 stops17h 31m

$4,800
Cheapest one-way

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Wed 11/11

12:18 pm-9:40 pm

1 stop9h 22m

$258

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 1/16

1:50 pm-10:55 pm

1 stop9h 05m

$258

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Wed 11/11

5:45 pm-9:42 am

2 stops39h 57m

$259

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 1/16

1:05 pm-11:31 pm

2 stops10h 26m

$263
Quickest one-way

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Sat 1/16

2:25 pm-10:37 pm

1 stop8h 12m

$574

George TownBuffalo

GCM George Town Owen Roberts Intl - BUF Buffalo

GCMBUF

George Town Owen Roberts Intl

Wed 11/11

5:45 pm-1:17 pm

3 stops19h 32m

$2,826

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Buffalo from

How to get the cheapest flight ticket from Cayman Islands to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Cayman Islands to Buffalo flights?

You could potentially save up to 54% on your flight if you consider stops on a Cayman Islands to Buffalo flight.

Cheap Cayman Islands to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cayman Islands to Buffalo

Fastest flight time

18h 54m

Direct flights

None
The fastest flight from Cayman Islands to Buffalo takes 18h 54m
There are no direct flights from Cayman Islands to Buffalo. There are no popular flight routes from Cayman Islands to Buffalo.
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Frequently asked questions about flying from the Cayman Islands to Buffalo

  • When did momondo last update prices for flights from Cayman Islands to Buffalo Airport?

    Prices for flights from Cayman Islands to Buffalo Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Cayman Islands to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cayman Islands to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Williamsville
Orchard Park
Grand Island
Bowmansville
West Seneca
Lockport
East Aurora
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Cayman Islands to Buffalo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Cayman Islands to Buffalo. momondo saves you time and could save you money on your trip.

Can I find flights from Cayman Islands to Buffalo with flexible booking policies on momondo?

Flights from Cayman Islands to Buffalo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Cayman Islands to Buffalo?

Once you have performed a search for Cayman Islands to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cayman Islands to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Cayman Islands to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

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