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Cheap flights from California to South America from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from California to South America departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
7:07 pm - 2:15 pm
LAX
-
MDE
16h 08m2 stops
Spirit Airlines Logo
3:15 pm - 6:02 pm
MDE
-
LAX
29h 47m2 stops
$335Spirit Airlines
Sun, Jan 25 - Wed, Feb 4
Multiple Airlines Logo
7:07 pm - 2:15 pm
LAX
-
MDE
16h 08m2 stops
Multiple Airlines Logo
9:48 am - 6:02 pm
MDE
-
LAX
35h 14m3 stops
$339Multiple Airlines
Tue, Jan 27 - Wed, Feb 4
Avianca Logo
2:10 pm - 7:05 am
LAX
-
MDE
13h 55m2 stops
Avianca Logo
2:10 pm - 10:00 pm
MDE
-
LAX
10h 50m1 stop
$351Avianca
Wed, Jan 28 - Sun, Feb 1
Avianca Logo
11:20 pm - 12:55 pm
LAX
-
MDE
10h 35m1 stop
Avianca Logo
2:10 pm - 9:15 pm
MDE
-
LAX
10h 05m1 stop
$356Avianca
Tue, Feb 17 - Thu, Feb 26
United Airlines Logo
6:15 am - 9:30 am
LAX
-
GRU
23h 15m1 stop
United Airlines Logo
10:20 pm - 4:28 pm
GRU
-
LAX
22h 08m1 stop
$500United Airlines
Tue, May 12 - Thu, May 28
American Airlines Logo
7:00 am - 8:10 am
LAX
-
GRU
20h 10m1 stop
American Airlines Logo
11:30 pm - 1:37 pm
GRU
-
LAX
19h 07m2 stops
$505American Airlines
Wed, Feb 25 - Mon, Mar 2
Copa Airlines Logo
2:06 am - 12:15 am
LAX
-
GRU
18h 09m1 stop
Copa Airlines Logo
11:10 am - 11:19 pm
GRU
-
LAX
16h 09m1 stop
$508Copa Airlines
Wed, Mar 18 - Mon, Apr 13
United Airlines Logo
12:40 pm - 7:15 am
LAX
-
GRU
37h 35m1 stop
United Airlines Logo
9:45 pm - 1:30 pm
GRU
-
LAX
20h 45m1 stop
$509United Airlines
Sat, Jan 31 - Wed, Feb 4
American Airlines Logo
6:15 am - 6:05 am
LAX
-
GRU
18h 50m1 stop
American Airlines Logo
12:15 am - 11:55 am
GRU
-
LAX
16h 40m1 stop
$525American Airlines
Wed, Jan 21 - Thu, Jan 29
Copa Airlines Logo
2:01 am - 12:15 am
LAX
-
GRU
18h 14m1 stop
Copa Airlines Logo
1:40 am - 11:29 pm
GRU
-
LAX
25h 49m1 stop
$538Copa Airlines
Thu, Mar 19 - Tue, Mar 24

LATAM Airlines flights from California to South America

Our best LATAM Airlines deals on California to South America flight tickets
LATAM Airlines
Jan 17
SFO5:55 amSan Francisco
13h 10m
1 stop
LIM10:05 pmLima J Chavez Intl
Jan 31
LIM12:15 pmLima J Chavez Intl
14h 10m
1 stop
SFO11:25 pmSan Francisco
$536
Find similar
LATAM Airlines
Feb 22
SFO6:00 amSan Francisco
20h 00m
1 stop
LIM5:00 amLima J Chavez Intl
Mar 10
LIM12:15 amLima J Chavez Intl
21h 05m
2 stops
SFO7:20 pmSan Francisco
$541
Find similar
LATAM Airlines
Jan 17
SFO5:55 amSan Francisco
13h 10m
1 stop
LIM10:05 pmLima J Chavez Intl
Jan 26
LIM12:50 amLima J Chavez Intl
14h 49m
1 stop
SFO12:39 pmSan Francisco
$548
Find similar

Avianca flights from California to South America

Our best Avianca deals on California to South America flight tickets
Avianca
Jan 28
LAX2:10 pmLos Angeles
13h 55m
2 stops
MDE7:05 amMedellín Jose Maria Cordova Intl
Feb 1
MDE2:10 pmMedellín Jose Maria Cordova Intl
10h 50m
1 stop
LAX10:00 pmLos Angeles
$351
Find similar
Avianca
Feb 17
LAX11:20 pmLos Angeles
10h 35m
1 stop
MDE12:55 pmMedellín Jose Maria Cordova Intl
Feb 26
MDE2:10 pmMedellín Jose Maria Cordova Intl
10h 05m
1 stop
LAX9:15 pmLos Angeles
$356
Find similar
Avianca
Jan 19
LAX2:10 pmLos Angeles
13h 10m
2 stops
MDE6:20 amMedellín Jose Maria Cordova Intl
Jan 22
MDE10:40 amMedellín Jose Maria Cordova Intl
13h 25m
2 stops
LAX9:05 pmLos Angeles
$357
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from California to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from California to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Sun 1/25

7:07 pm-2:15 pm

2 stops16h 08m

Medellín Jose Maria Cordova Intl

Wed 2/4

3:15 pm-6:02 pm

2 stops29h 47m

$335

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Tue 1/27

7:07 pm-2:15 pm

2 stops16h 08m

Medellín Jose Maria Cordova Intl

Wed 2/4

9:48 am-6:02 pm

3 stops35h 14m

$339

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Wed 1/28

2:10 pm-7:05 am

2 stops13h 55m

Medellín Jose Maria Cordova Intl

Sun 2/1

2:10 pm-10:00 pm

1 stop10h 50m

$351

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Tue 2/17

11:20 pm-12:55 pm

1 stop10h 35m

Medellín Jose Maria Cordova Intl

Thu 2/26

2:10 pm-9:15 pm

1 stop10h 05m

$356

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Tue 5/12

6:15 am-9:30 am

1 stop23h 15m

Sao Paulo Guarulhos Intl

Thu 5/28

10:20 pm-4:28 pm

1 stop22h 08m

$500

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Wed 2/25

7:00 am-8:10 am

1 stop20h 10m

Sao Paulo Guarulhos Intl

Mon 3/2

11:30 pm-1:37 pm

2 stops19h 07m

$505

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Wed 3/18

2:06 am-12:15 am

1 stop18h 09m

Sao Paulo Guarulhos Intl

Mon 4/13

11:10 am-11:19 pm

1 stop16h 09m

$508

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Sat 1/31

12:40 pm-7:15 am

1 stop37h 35m

Sao Paulo Guarulhos Intl

Wed 2/4

9:45 pm-1:30 pm

1 stop20h 45m

$509

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Wed 1/21

6:15 am-6:05 am

1 stop18h 50m

Sao Paulo Guarulhos Intl

Thu 1/29

12:15 am-11:55 am

1 stop16h 40m

$525

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Thu 3/19

2:01 am-12:15 am

1 stop18h 14m

Sao Paulo Guarulhos Intl

Tue 3/24

1:40 am-11:29 pm

1 stop25h 49m

$538

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from California to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from California to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $707. If you aren’t able to travel during the month of February, then book flights to South America from California during January instead. Flights to South America in January, while not as cheap as those in February, still average around $715.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from California to South America is on a Monday when prices can be found for as low as $877. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from California to South America for around $985.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest California to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $691. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $981 on average. Flights to South America from California in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest California to South America flight route?

Fly from Los Angeles to Sao Paulo Guarulhos Intl for the best California - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from California when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $780 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from California for as low as $725 on momondo.

What cabin class options are available on California to South America flights?

There are 4 cabin classes available to choose from on California to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on California to South America flights?

You could potentially save up to 44% on your flight if you consider stops on a California to South America flight.

Cheap California to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from California to South America

Best Price Found

$323

Fastest flight time

8h 05m

Direct flights

Tue, Wed, Thu, Fri, Sat and Sun

Airports in South America

1 airport
The best one-way flight to South America from California in the past 72 hours is $323. The best round-trip flight deal from California to South America found on momondo in the last 72 hours is $769.
The fastest flight from California to South America takes 8h 05m
Direct flights go from California to South America on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is LATAM Airlines.
There is 1 airport near South America: Lima J Chavez Intl (LIM)
Search flight deals

  • When did momondo last update prices for flights from California to South America?

    Prices for flights from California to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from California to South America?

  • How old do you have to be to fly from California to South America?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from California to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from California to South America?

Best airlines flying from California to South America

Compare and see reviews for airlines that fly from California to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $156Free CancellationRating
6.3
8,157 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $283Free CancellationRating
7.4
9,066 reviews
Search United Airlines flights
AviancaPriceFrom $301Free CancellationRating
6.6
2,479 reviews
Search Avianca flights
Copa AirlinesPriceFrom $342Free CancellationRating
7.6
1,554 reviews
Search Copa Airlines flights
DeltaPriceFrom $366Free CancellationRating
7.9
8,011 reviews
Search Delta flights
JetBluePriceFrom $409Free CancellationRating
7.2
2,899 reviews
Search JetBlue flights
LATAM AirlinesPriceFrom $420Free CancellationRating
7.5
1,890 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $452Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
AeromexicoPriceFrom $490Free CancellationRating
7.4
1,650 reviews
Search Aeromexico flights
Air CanadaPriceFrom $531Free CancellationRating
7.1
10,500 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from California to South America?

It is quick and easy to find California to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from California to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for California to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from California to South America?

Once all potential California to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from California to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for California to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $227
Flights to Buenos Airesfrom $478
Flights to Bogotáfrom $175
Flights to Sao Paulofrom $314
Flights to Rio de Janeirofrom $455
Flights to Medellínfrom $166
Flights to Santiagofrom $351
Flights to Cartagenafrom $176
Flights to Quitofrom $231
Flights to Cuscofrom $366
Flights to Guayaquilfrom $198
Flights to Califrom $193