Cheap flights from California to South America from $197

In general, September is the cheapest month to fly from California to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $623. If you aren’t able to travel during the month of September, then book flights to South America from California during October instead. Flights to South America in October, while not as cheap as those in September, still average around $672.

The cheapest day to depart from California to South America is on a Monday when prices can be found for as low as $877. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from California to South America for around $1,006.

Our data shows that the cheapest California to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $910. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $974 on average. Flights to South America from California in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Los Angeles to Santiago Arturo Merino Benitez for the best California - South America flight prices

You are more likely to see cheaper flights to South America from California when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $806 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from California for as low as $770 on momondo.

There are 4 cabin classes available to choose from on California to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Copa Airlines, United Airlines, and LATAM Airlines are the most popular carriers operating from California to South America

Copa Airlines, LATAM Airlines and United Airlines are the top three most popular airlines that fly to South America from California according to our data. Copa Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 11 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

The number of flights available between California and South America is 13 per day as of June 2026. The most frequent departure time is 9:00PM, with 37% of daily flights leaving in the evening.

As of June 2026, there are 94 flights per week flying from California to South America. The most common day of the week flights depart is Wed, with 19% of flights taking off on this day.