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Cheap flights from California to South America from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from California to South America departing on 11/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Copa Airlines Logo
11:05 am - 8:18 amLAX-MDE
18h 13m1 stop
Copa Airlines Logo
10:46 am - 10:44 pmMDE-LAX
14h 58m1 stop
$381Copa Airlines
Find Deal
Tue, Nov 4 - Sun, Nov 9
Spirit Airlines Logo
4:56 pm - 2:03 pmLAX-MDE
18h 07m2 stops
Spirit Airlines Logo
1:52 am - 3:51 pmMDE-LAX
16h 59m2 stops
$382Spirit Airlines
Find Deal
Fri, Nov 14 - Sat, Nov 15
Multiple Airlines Logo
2:25 pm - 12:57 amLAX-MDE
31h 32m2 stops
Multiple Airlines Logo
3:14 pm - 8:39 pmMDE-LAX
32h 25m1 stop
$384Multiple Airlines
Find Deal
Fri, Nov 14 - Fri, Nov 21
Multiple Airlines Logo
11:53 am - 12:57 amLAX-MDE
10h 04m1 stop
Multiple Airlines Logo
2:57 pm - 1:18 pmMDE-LAX
25h 21m2 stops
$386Multiple Airlines
Find Deal
Mon, Nov 10 - Fri, Nov 14
Avianca Logo
1:00 am - 4:45 pmLAX-MDE
13h 45m2 stops
Avianca Logo
11:00 am - 11:00 pmMDE-LAX
14h 00m2 stops
$408Avianca
Find Deal
Wed, Oct 22 - Fri, Oct 31
Avianca Logo
1:50 pm - 10:45 amLAX-LIM
17h 55m3 stops
Avianca Logo
3:00 am - 9:15 pmLIM-LAX
21h 15m1 stop
$484Avianca
Find Deal
Thu, Feb 5 - Fri, Feb 27
United Airlines Logo
8:15 am - 7:15 amLAX-GRU
19h 00m1 stop
United Airlines Logo
9:45 pm - 3:30 pmGRU-LAX
22h 45m1 stop
$500United Airlines
Find Deal
Sun, Oct 26 - Mon, Nov 10
American Airlines Logo
1:05 pm - 8:05 amLAX-GRU
14h 00m1 stop
American Airlines Logo
10:35 pm - 11:50 amGRU-LAX
18h 15m1 stop
$501American Airlines
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Thu, Nov 13 - Thu, Nov 20
American Airlines Logo
10:20 am - 6:05 amLAX-GRU
15h 45m1 stop
American Airlines Logo
10:35 pm - 12:25 pmGRU-LAX
18h 50m2 stops
$502American Airlines
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Wed, Oct 29 - Sat, Nov 8
United Airlines Logo
11:20 pm - 7:15 amLAX-GRU
27h 55m1 stop
United Airlines Logo
10:25 pm - 12:04 pmGRU-LAX
18h 39m1 stop
$509United Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 11

United Airlines flights from California to South America

Our best United Airlines deals on California to South America flight tickets
United Airlines
Oct 22
LAX5:31 amLos Angeles
13h 39m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
Oct 30
MDE9:45 amMedellín Jose Maria Cordova Intl
16h 14m
1 stop
LAX11:59 pmLos Angeles
$399
Find similar
United Airlines
Oct 22
LAX12:56 amLos Angeles
18h 14m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
Oct 31
MDE9:45 amMedellín Jose Maria Cordova Intl
12h 37m
1 stop
LAX8:22 pmLos Angeles
$453
Find similar
United Airlines
Oct 28
LAX12:55 amLos Angeles
18h 10m
1 stop
MDE9:05 pmMedellín Jose Maria Cordova Intl
Nov 1
MDE9:45 amMedellín Jose Maria Cordova Intl
26h 24m
1 stop
LAX10:09 amLos Angeles
$463
Find similar

American Airlines flights from California to South America

Our best American Airlines deals on California to South America flight tickets
American Airlines
Oct 22
LAX6:15 amLos Angeles
12h 00m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
Oct 30
MDE6:00 amMedellín Jose Maria Cordova Intl
17h 39m
2 stops
LAX9:39 pmLos Angeles
$458
Find similar
American Airlines
Oct 22
LAX6:15 amLos Angeles
12h 00m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
Oct 24
MDE6:00 amMedellín Jose Maria Cordova Intl
14h 15m
2 stops
LAX6:15 pmLos Angeles
$490
Find similar
American Airlines
Oct 22
LAX7:49 pmLos Angeles
14h 46m
2 stops
MDE12:35 pmMedellín Jose Maria Cordova Intl
Oct 27
MDE6:00 amMedellín Jose Maria Cordova Intl
20h 18m
1 stop
LAX12:18 amLos Angeles
$491
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from California to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from California to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Tue 11/4

11:05 am-8:18 am

1 stop18h 13m

Medellín Jose Maria Cordova Intl

Sun 11/9

10:46 am-10:44 pm

1 stop14h 58m

$381

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Fri 11/14

4:56 pm-2:03 pm

2 stops18h 07m

Medellín Jose Maria Cordova Intl

Sat 11/15

1:52 am-3:51 pm

2 stops16h 59m

$382

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Fri 11/14

2:25 pm-12:57 am

2 stops31h 32m

Medellín Jose Maria Cordova Intl

Fri 11/21

3:14 pm-8:39 pm

1 stop32h 25m

$384

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Mon 11/10

11:53 am-12:57 am

1 stop10h 04m

Medellín Jose Maria Cordova Intl

Fri 11/14

2:57 pm-1:18 pm

2 stops25h 21m

$386

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Wed 10/22

1:00 am-4:45 pm

2 stops13h 45m

Medellín Jose Maria Cordova Intl

Fri 10/31

11:00 am-11:00 pm

2 stops14h 00m

$408

Los AngelesLima

LAX - LIM

LAXLIM

Los Angeles

Thu 2/5

1:50 pm-10:45 am

3 stops17h 55m

Lima J Chavez Intl

Fri 2/27

3:00 am-9:15 pm

1 stop21h 15m

$484

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Sun 10/26

8:15 am-7:15 am

1 stop19h 00m

Sao Paulo Guarulhos Intl

Mon 11/10

9:45 pm-3:30 pm

1 stop22h 45m

$500

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Thu 11/13

1:05 pm-8:05 am

1 stop14h 00m

Sao Paulo Guarulhos Intl

Thu 11/20

10:35 pm-11:50 am

1 stop18h 15m

$501

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Wed 10/29

10:20 am-6:05 am

1 stop15h 45m

Sao Paulo Guarulhos Intl

Sat 11/8

10:35 pm-12:25 pm

2 stops18h 50m

$502

Los AngelesSao Paulo

LAX - GRU

LAXGRU

Los Angeles

Sat 11/1

11:20 pm-7:15 am

1 stop27h 55m

Sao Paulo Guarulhos Intl

Tue 11/11

10:25 pm-12:04 pm

1 stop18h 39m

$509

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from California to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from California to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $708. If you aren’t able to travel during the month of February, then book flights to South America from California during September instead. Flights to South America in September, while not as cheap as those in February, still average around $716.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from California to South America is on a Monday when prices can be found for as low as $875. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from California to South America for around $983.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest California to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $691. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $972 on average. Flights to South America from California in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest California to South America flight route?

Fly from Los Angeles to Sao Paulo Guarulhos Intl for the best California - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from California when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $787 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from California for as low as $732 on momondo.

What cabin class options are available on California to South America flights?

There are 4 cabin classes available to choose from on California to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on California to South America flights?

You could potentially save up to 74% on your flight if you consider stops on a California to South America flight.

Cheap California to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from California to South America

Best Price Found

$344

Fastest flight time

8h 15m

Direct flights

Every day

Airports in South America

1 airport
The best one-way flight to South America from California in the past 72 hours is $344. The best round-trip flight deal from California to South America found on momondo in the last 72 hours is $827.
The fastest flight from California to South America takes 8h 15m
Direct flights go from California to South America every day.
There is 1 airport near South America: Lima J Chavez Intl (LIM)
Search flight deals

  • When did momondo last update prices for flights from California to South America?

    Prices for flights from California to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from California to South America?

  • How old do you have to be to fly from California to South America?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from California to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from California to South America?

Best airlines flying from California to South America

Compare and see reviews for airlines that fly from California to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $173Free CancellationRating
6.3
8,099 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $283Free CancellationRating
7.4
8,982 reviews
Search United Airlines flights
AviancaPriceFrom $293Free CancellationRating
6.6
2,452 reviews
Search Avianca flights
Copa AirlinesPriceFrom $337Free CancellationRating
7.6
1,551 reviews
Search Copa Airlines flights
VivaPriceFrom $361Free CancellationRating
7.0
789 reviews
Search Viva flights
DeltaPriceFrom $389Free CancellationRating
7.9
7,977 reviews
Search Delta flights
LATAM AirlinesPriceFrom $399Free CancellationRating
7.5
1,866 reviews
Search LATAM Airlines flights
JetBluePriceFrom $409Free CancellationRating
7.2
2,907 reviews
Search JetBlue flights
American AirlinesPriceFrom $449Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
AeromexicoPriceFrom $490Free CancellationRating
7.4
1,683 reviews
Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from California to South America?

It is quick and easy to find California to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from California to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for California to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from California to South America?

Once all potential California to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from California to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for California to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

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Sat 11/15
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $264
Flights to Buenos Airesfrom $490
Flights to Bogotáfrom $182
Flights to Sao Paulofrom $381
Flights to Rio de Janeirofrom $466
Flights to Medellínfrom $165
Flights to Santiagofrom $381
Flights to Cartagenafrom $182
Flights to Quitofrom $298
Flights to Cuscofrom $430
Flights to Califrom $196
Flights to Guayaquilfrom $217