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Cheap flights from Brussels Bruxelles-National Airport to Des Moines from $458

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Brussels Bruxelles-National Airport to Des Moines departing on 1/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Brussels Bruxelles-National Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:10 am - 9:27 pmBRU-DSM
22h 17m2 stops
Delta Logo
11:04 am - 8:40 amDSM-BRU
14h 36m1 stop
$809Delta
Find Deal
Wed, Apr 1 - Sun, Apr 5
Delta Logo
8:00 am - 9:27 pmBRU-DSM
20h 27m2 stops
Delta Logo
11:04 am - 8:40 amDSM-BRU
14h 36m1 stop
$810Delta
Find Deal
Wed, Apr 1 - Sun, Apr 5
Delta Logo
10:25 am - 9:27 pmBRU-DSM
18h 02m2 stops
Delta Logo
5:25 pm - 2:35 pmDSM-BRU
14h 10m2 stops
$811Delta
Find Deal
Wed, Apr 1 - Sun, Apr 5
Delta Logo
8:00 am - 4:30 pmBRU-DSM
15h 30m2 stops
Delta Logo
10:55 am - 9:40 amDSM-BRU
15h 45m2 stops
$812Delta
Find Deal
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
10:15 am - 5:33 pmBRU-DSM
14h 18m1 stop
United Airlines Logo
11:30 am - 9:00 amDSM-BRU
14h 30m1 stop
$1,392United Airlines
Find Deal
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
10:15 am - 9:36 pmBRU-DSM
18h 21m1 stop
United Airlines Logo
11:30 am - 9:00 amDSM-BRU
14h 30m1 stop
$1,393United Airlines
Find Deal
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
10:15 am - 5:33 pmBRU-DSM
14h 18m1 stop
United Airlines Logo
3:15 pm - 9:00 amDSM-BRU
10h 45m1 stop
$1,395United Airlines
Find Deal
Wed, Apr 1 - Sun, Apr 5

Delta flights from Brussels Bruxelles-National Airport to Des Moines

Our best Delta deals on Brussels Bruxelles-National Airport to Des Moines flight tickets
Delta
Apr 1
BRU6:10 amBrussels Bruxelles-National
22h 17m
2 stops
DSM9:27 pmDes Moines
Apr 5
DSM11:04 amDes Moines
14h 36m
1 stop
BRU8:40 amBrussels Bruxelles-National
$809
Find similar
Delta
Apr 1
BRU8:00 amBrussels Bruxelles-National
20h 27m
2 stops
DSM9:27 pmDes Moines
Apr 5
DSM11:04 amDes Moines
14h 36m
1 stop
BRU8:40 amBrussels Bruxelles-National
$810
Find similar
Delta
Apr 1
BRU10:25 amBrussels Bruxelles-National
18h 02m
2 stops
DSM9:27 pmDes Moines
Apr 5
DSM5:25 pmDes Moines
14h 10m
2 stops
BRU2:35 pmBrussels Bruxelles-National
$811
Find similar

United Airlines flights from Brussels Bruxelles-National Airport to Des Moines

Our best United Airlines deals on Brussels Bruxelles-National Airport to Des Moines flight tickets
United Airlines
Apr 1
BRU10:15 amBrussels Bruxelles-National
14h 18m
1 stop
DSM5:33 pmDes Moines
Apr 5
DSM11:30 amDes Moines
14h 30m
1 stop
BRU9:00 amBrussels Bruxelles-National
$1,392
Find similar
United Airlines
Apr 1
BRU10:15 amBrussels Bruxelles-National
18h 21m
1 stop
DSM9:36 pmDes Moines
Apr 5
DSM11:30 amDes Moines
14h 30m
1 stop
BRU9:00 amBrussels Bruxelles-National
$1,393
Find similar
United Airlines
Apr 1
BRU10:15 amBrussels Bruxelles-National
14h 18m
1 stop
DSM5:33 pmDes Moines
Apr 5
DSM3:15 pmDes Moines
10h 45m
1 stop
BRU9:00 amBrussels Bruxelles-National
$1,395
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Brussels Bruxelles-National Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

6:10 am-9:27 pm

2 stops22h 17m

Des Moines

Sun 4/5

11:04 am-8:40 am

1 stop14h 36m

$809

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

8:00 am-9:27 pm

2 stops20h 27m

Des Moines

Sun 4/5

11:04 am-8:40 am

1 stop14h 36m

$810

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

10:25 am-9:27 pm

2 stops18h 02m

Des Moines

Sun 4/5

5:25 pm-2:35 pm

2 stops14h 10m

$811

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

8:00 am-4:30 pm

2 stops15h 30m

Des Moines

Sun 4/5

10:55 am-9:40 am

2 stops15h 45m

$812

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

10:15 am-5:33 pm

1 stop14h 18m

Des Moines

Sun 4/5

11:30 am-9:00 am

1 stop14h 30m

$1,392

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

10:15 am-9:36 pm

1 stop18h 21m

Des Moines

Sun 4/5

11:30 am-9:00 am

1 stop14h 30m

$1,393

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 4/1

10:15 am-5:33 pm

1 stop14h 18m

Des Moines

Sun 4/5

3:15 pm-9:00 am

1 stop10h 45m

$1,395

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sun 1/18

9:35 pm-9:04 pm

2 stops30h 29m

$458

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sun 1/18

10:15 am-7:31 pm

3 stops40h 16m

$676

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sun 1/18

10:10 am-9:50 pm

1 stop18h 40m

$764

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Des Moines from

How to get the cheapest flight ticket from Brussels Bruxelles-National Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Brussels Bruxelles-National Airport to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $956. Flights from Brussels Bruxelles-National Airport to Des Moines on a Friday will generally be more expensive and average around $1,325. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

When to book flights from Brussels Bruxelles-National Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Brussels Bruxelles-National Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Brussels Bruxelles-National Airport to Des Moines (BRU to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Brussels Bruxelles-National Airport to Des Moines

Direct flights

None
There are no direct flights from Brussels Bruxelles-National Airport to Des Moines. There are no popular flight routes from Brussels Bruxelles-National Airport to Des Moines.
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  • How far is Brussels Bruxelles-National to Des Moines by plane?

    The straight-line distance from Brussels Bruxelles-National to Des Moines is 4374.0 mi. Typically, this will take 14h 18m by plane in normal conditions.

  • When did momondo last update prices for flights from Brussels Bruxelles-National Airport to Des Moines Airport?

    Prices for flights from Brussels Bruxelles-National Airport to Des Moines Airport are updated daily.

  • How old do you have to be to fly from Brussels Bruxelles-National Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Brussels Bruxelles-National Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Brussels to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Brussels.

Can I find flights from Brussels to Des Moines with flexible booking policies on momondo?

All flight searches from Brussels to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Brussels to Des Moines?

momondo helps you find the best flight between Brussels and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Brussels to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Brussels are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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