Find trains from Louisville to Chicago

The quickest train available from Louisville Intl will take 5h 00m to arrive in Chicago. For this route, you may experience slight differences in travel time depending on the train you book. Look for nonstop options when searching if possible.

A train from Louisville Intl to Chicago will travel much more than the 269.2 mi distance between them. The actual distance depends on the route taken, and stops along the way. Most trains from Louisville Intl to Chicago will get there in 5h 00m.