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Cheap flights from Tallahassee to Des Moines from $448

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tallahassee to Des Moines departing on 3/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Tallahassee to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:15 am - 12:55 pm
TLH
-
DSM
7h 40m
1 stop
American Airlines Logo
3:00 pm - 10:41 pm
DSM
-
TLH
6h 41m
1 stop
$474American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
6:27 am - 1:07 pm
TLH
-
DSM
7h 40m
1 stop
American Airlines Logo
2:02 pm - 10:41 pm
DSM
-
TLH
7h 39m
1 stop
$475American Airlines
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
6:09 am - 1:46 pm
TLH
-
DSM
8h 37m
2 stops
American Airlines Logo
3:00 pm - 10:41 pm
DSM
-
TLH
6h 41m
1 stop
$479American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
6:00 am - 10:44 am
TLH
-
DSM
5h 44m
1 stop
American Airlines Logo
12:00 pm - 10:41 pm
DSM
-
TLH
9h 41m
2 stops
$480American Airlines
Sat, Apr 4 - Wed, Apr 8
Delta Logo
5:36 am - 10:48 am
TLH
-
DSM
6h 12m
1 stop
Delta Logo
11:33 am - 7:32 pm
DSM
-
TLH
6h 59m
1 stop
$495Delta
Sat, Apr 4 - Tue, Apr 7
Delta Logo
5:36 am - 10:48 am
TLH
-
DSM
6h 12m
1 stop
Delta Logo
6:15 am - 3:05 pm
DSM
-
TLH
7h 50m
2 stops
$500Delta
Sat, Apr 4 - Tue, Apr 7
Delta Logo
5:36 am - 10:48 am
TLH
-
DSM
6h 12m
1 stop
Delta Logo
5:20 pm - 10:33 pm
DSM
-
TLH
4h 13m
1 stop
$501Delta
Sat, Apr 4 - Mon, Apr 6
Delta Logo
7:39 am - 3:42 pm
TLH
-
DSM
9h 03m
2 stops
Delta Logo
10:28 am - 8:44 pm
DSM
-
TLH
9h 16m
2 stops
$505Delta
Sat, Mar 28 - Wed, Apr 1
Delta Logo
5:36 am - 10:48 am
TLH
-
DSM
6h 12m
1 stop
Delta Logo
6:15 am - 4:27 pm
DSM
-
TLH
9h 12m
2 stops
$506Delta
Sat, Apr 4 - Mon, Apr 6
Delta Logo
7:09 pm - 10:38 pm
TLH
-
DSM
4h 29m
1 stop
Delta Logo
11:33 am - 4:27 pm
DSM
-
TLH
3h 54m
1 stop
$541Delta
Fri, Apr 3 - Wed, Apr 8

American Airlines flights from Tallahassee to Des Moines

Our best American Airlines deals on Tallahassee to Des Moines flight tickets
American Airlines
Mar 28
TLH6:54 pmTallahassee
5h 52m
1 stop
DSM11:46 pmDes Moines
Apr 1
DSM3:26 pmDes Moines
6h 28m
1 stop
TLH10:54 pmTallahassee
$475
American Airlines
Mar 28
TLH6:27 amTallahassee
7h 40m
1 stop
DSM1:07 pmDes Moines
Apr 1
DSM6:40 amDes Moines
8h 36m
2 stops
TLH4:16 pmTallahassee
$480
American Airlines
Apr 4
TLH6:54 pmTallahassee
5h 52m
1 stop
DSM11:46 pmDes Moines
Apr 9
DSM11:09 amDes Moines
10h 32m
2 stops
TLH10:41 pmTallahassee
$556

Delta flights from Tallahassee to Des Moines

Our best Delta deals on Tallahassee to Des Moines flight tickets
Delta
Apr 4
TLH5:36 amTallahassee
6h 12m
1 stop
DSM10:48 amDes Moines
Apr 7
DSM11:33 amDes Moines
6h 59m
1 stop
TLH7:32 pmTallahassee
$495
Delta
Apr 4
TLH5:36 amTallahassee
6h 12m
1 stop
DSM10:48 amDes Moines
Apr 7
DSM6:15 amDes Moines
7h 50m
2 stops
TLH3:05 pmTallahassee
$500
Delta
Apr 4
TLH5:36 amTallahassee
6h 12m
1 stop
DSM10:48 amDes Moines
Apr 6
DSM5:20 pmDes Moines
4h 13m
1 stop
TLH10:33 pmTallahassee
$501

momondo Fare Finder

 
Customize your flight search to find flights from Tallahassee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Tallahassee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Thu 4/9

6:15 am-12:55 pm

1 stop7h 40m

Des Moines

Mon 4/13

3:00 pm-10:41 pm

1 stop6h 41m

$474

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 4/4

6:27 am-1:07 pm

1 stop7h 40m

Des Moines

Wed 4/8

2:02 pm-10:41 pm

1 stop7h 39m

$475

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Thu 4/9

6:09 am-1:46 pm

2 stops8h 37m

Des Moines

Mon 4/13

3:00 pm-10:41 pm

1 stop6h 41m

$479

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 4/4

6:00 am-10:44 am

1 stop5h 44m

Des Moines

Wed 4/8

12:00 pm-10:41 pm

2 stops9h 41m

$480

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 4/4

5:36 am-10:48 am

1 stop6h 12m

Des Moines

Tue 4/7

11:33 am-7:32 pm

1 stop6h 59m

$495

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 4/4

5:36 am-10:48 am

1 stop6h 12m

Des Moines

Tue 4/7

6:15 am-3:05 pm

2 stops7h 50m

$500

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 4/4

5:36 am-10:48 am

1 stop6h 12m

Des Moines

Mon 4/6

5:20 pm-10:33 pm

1 stop4h 13m

$501

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 3/28

7:39 am-3:42 pm

2 stops9h 03m

Des Moines

Wed 4/1

10:28 am-8:44 pm

2 stops9h 16m

$505

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sat 4/4

5:36 am-10:48 am

1 stop6h 12m

Des Moines

Mon 4/6

6:15 am-4:27 pm

2 stops9h 12m

$506
Quickest round-trip

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Fri 4/3

7:09 pm-10:38 pm

1 stop4h 29m

Des Moines

Wed 4/8

11:33 am-4:27 pm

1 stop3h 54m

$541

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Tallahassee to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Tallahassee to Des Moines?

American Airlines is the most popular carrier operating from Tallahassee to Des Moines

When to book flights from Tallahassee to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tallahassee to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tallahassee to Des Moines (TLH to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tallahassee to Des Moines

Fastest flight time

6h 12m

Direct flights

None
The fastest flight from Tallahassee to Des Moines takes 6h 12m
There are no direct flights from Tallahassee to Des Moines. There are no popular flight routes from Tallahassee to Des Moines.
Search flight deals

  • How far is Tallahassee to Des Moines by plane?

    Tallahassee and Des Moines are 928.7 mi apart from one another. Typically, this will take 6h 12m by plane in normal conditions.

  • When did momondo last update prices for flights from Tallahassee Airport to Des Moines Airport?

    Prices for flights from Tallahassee Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Tallahassee Airport to Des Moines Airport?

  • How old do you have to be to fly from Tallahassee Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Tallahassee Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Tallahassee to Des Moines?

Best airlines flying from Tallahassee to Des Moines

Compare and see reviews for airlines that fly from Tallahassee to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $336Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tallahassee to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Tallahassee to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Tallahassee to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Tallahassee with this policy.

How can momondo help me find flights from Tallahassee to Des Moines?

Once you have performed a search for Tallahassee to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tallahassee to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Tallahassee and alert you when they change.

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