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Cheap flights from Tallahassee to Des Moines from $353

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tallahassee to Des Moines departing on 9/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tallahassee to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
8:07 am - 11:21 am
TLH
-
DSM
4h 14m
1 stop
Delta Logo
5:45 am - 11:15 am
DSM
-
TLH
4h 30m
1 stop
$413Delta
Sun, Sep 6 - Fri, Sep 11
Delta Logo
8:07 am - 11:21 am
TLH
-
DSM
4h 14m
1 stop
Delta Logo
5:45 am - 11:15 am
DSM
-
TLH
4h 30m
1 stop
$413Delta
Sun, Sep 6 - Tue, Sep 15
Delta Logo
6:00 am - 10:43 am
TLH
-
DSM
5h 43m
1 stop
Delta Logo
5:45 am - 11:15 am
DSM
-
TLH
4h 30m
1 stop
$445Delta
Mon, Sep 7 - Tue, Sep 15
American Airlines Logo
1:28 pm - 6:58 pm
TLH
-
DSM
6h 30m
1 stop
American Airlines Logo
7:00 am - 2:52 pm
DSM
-
TLH
6h 52m
1 stop
$455American Airlines
Thu, Sep 10 - Sun, Sep 13
Delta Logo
12:00 pm - 3:15 pm
TLH
-
DSM
4h 15m
1 stop
Delta Logo
5:45 am - 11:15 am
DSM
-
TLH
4h 30m
1 stop
$476Delta
Wed, Sep 9 - Tue, Sep 15
Delta Logo
12:00 pm - 3:15 pm
TLH
-
DSM
4h 15m
1 stop
Delta Logo
5:45 am - 11:15 am
DSM
-
TLH
4h 30m
1 stop
$476Delta
Wed, Sep 9 - Fri, Sep 11
Delta Logo
5:45 pm - 10:37 pm
TLH
-
DSM
5h 52m
1 stop
Delta Logo
4:10 pm - 10:48 pm
DSM
-
TLH
5h 38m
1 stop
$476Delta
Sun, Sep 6 - Sat, Sep 12
Multiple Airlines Logo
8:08 am - 11:19 pm
TLH
-
DSM
16h 11m
2 stops
Multiple Airlines Logo
6:07 pm - 8:58 am
DSM
-
TLH
13h 51m
1 stop
$477Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
American Airlines Logo
1:28 pm - 6:58 pm
TLH
-
DSM
6h 30m
1 stop
American Airlines Logo
6:41 am - 12:55 pm
DSM
-
TLH
5h 14m
1 stop
$493American Airlines
Thu, Sep 10 - Sat, Sep 12
American Airlines Logo
1:28 pm - 6:58 pm
TLH
-
DSM
6h 30m
1 stop
American Airlines Logo
4:14 pm - 10:52 pm
DSM
-
TLH
5h 38m
1 stop
$493American Airlines
Thu, Sep 10 - Fri, Sep 11

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Delta flights from Tallahassee to Des Moines

Our best Delta deals on Tallahassee to Des Moines flight tickets
Delta
Sep 6
TLH8:07 amTallahassee
4h 14m
1 stop
DSM11:21 amDes Moines
Sep 11
DSM5:45 amDes Moines
4h 30m
1 stop
TLH11:15 amTallahassee
$413
Delta
Sep 7
TLH6:00 amTallahassee
5h 43m
1 stop
DSM10:43 amDes Moines
Sep 15
DSM5:45 amDes Moines
4h 30m
1 stop
TLH11:15 amTallahassee
$445
Delta
Sep 9
TLH12:00 pmTallahassee
4h 15m
1 stop
DSM3:15 pmDes Moines
Sep 15
DSM5:45 amDes Moines
4h 30m
1 stop
TLH11:15 amTallahassee
$476

American Airlines flights from Tallahassee to Des Moines

Our best American Airlines deals on Tallahassee to Des Moines flight tickets
American Airlines
Sep 10
TLH1:28 pmTallahassee
6h 30m
1 stop
DSM6:58 pmDes Moines
Sep 13
DSM7:00 amDes Moines
6h 52m
1 stop
TLH2:52 pmTallahassee
$455
American Airlines
Sep 10
TLH1:28 pmTallahassee
6h 30m
1 stop
DSM6:58 pmDes Moines
Sep 11
DSM4:14 pmDes Moines
5h 38m
1 stop
TLH10:52 pmTallahassee
$493
American Airlines
Sep 10
TLH1:28 pmTallahassee
6h 30m
1 stop
DSM6:58 pmDes Moines
Sep 15
DSM4:14 pmDes Moines
5h 38m
1 stop
TLH10:52 pmTallahassee
$515

momondo Fare Finder

 
Customize your flight search to find flights from Tallahassee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Tallahassee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sun 9/6

8:07 am-11:21 am

1 stop4h 14m

Des Moines

Fri 9/11

5:45 am-11:15 am

1 stop4h 30m

$413

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sun 9/6

8:07 am-11:21 am

1 stop4h 14m

Des Moines

Tue 9/15

5:45 am-11:15 am

1 stop4h 30m

$413

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Mon 9/7

6:00 am-10:43 am

1 stop5h 43m

Des Moines

Tue 9/15

5:45 am-11:15 am

1 stop4h 30m

$445

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Thu 9/10

1:28 pm-6:58 pm

1 stop6h 30m

Des Moines

Sun 9/13

7:00 am-2:52 pm

1 stop6h 52m

$455

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Wed 9/9

12:00 pm-3:15 pm

1 stop4h 15m

Des Moines

Tue 9/15

5:45 am-11:15 am

1 stop4h 30m

$476

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Wed 9/9

12:00 pm-3:15 pm

1 stop4h 15m

Des Moines

Fri 9/11

5:45 am-11:15 am

1 stop4h 30m

$476

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Sun 9/6

5:45 pm-10:37 pm

1 stop5h 52m

Des Moines

Sat 9/12

4:10 pm-10:48 pm

1 stop5h 38m

$476

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Thu 8/13

8:08 am-11:19 pm

2 stops16h 11m

Des Moines

Mon 8/17

6:07 pm-8:58 am

1 stop13h 51m

$477

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Thu 9/10

1:28 pm-6:58 pm

1 stop6h 30m

Des Moines

Sat 9/12

6:41 am-12:55 pm

1 stop5h 14m

$493

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Thu 9/10

1:28 pm-6:58 pm

1 stop6h 30m

Des Moines

Fri 9/11

4:14 pm-10:52 pm

1 stop5h 38m

$493

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Tallahassee to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Tallahassee to Des Moines?

American Airlines is the most popular carrier operating from Tallahassee to Des Moines

When to book flights from Tallahassee to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tallahassee to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tallahassee to Des Moines (TLH to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tallahassee to Des Moines

Fastest flight time

5h 37m

Direct flights

None
The fastest flight from Tallahassee to Des Moines takes 5h 37m
There are no direct flights from Tallahassee to Des Moines. There are no popular flight routes from Tallahassee to Des Moines.
Search flight deals

Frequently asked questions about flying from Tallahassee to Des Moines

  • How far is Tallahassee to Des Moines by plane?

    Tallahassee and Des Moines are 928.7 mi apart from one another. Typically, this will take 5h 37m by plane in normal conditions.

  • When did momondo last update prices for flights from Tallahassee Airport to Des Moines Airport?

    Prices for flights from Tallahassee Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Tallahassee Airport to Des Moines Airport?

  • How old do you have to be to fly from Tallahassee Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Tallahassee Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Tallahassee to Des Moines?

Best airlines flying from Tallahassee to Des Moines

Compare and see reviews for airlines that fly from Tallahassee to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $336Free CancellationRating
7.1
11,839 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Johnston
Osceola
Newton
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tallahassee to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Tallahassee to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Tallahassee to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Tallahassee with this policy.

How can momondo help me find flights from Tallahassee to Des Moines?

Once you have performed a search for Tallahassee to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tallahassee to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Tallahassee and alert you when they change.

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