What airlines fly to Des Moines?

Delta, United Airlines and American Airlines are the top three most popular airlines that fly to Des Moines from Syracuse according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Syracuse Hancock Intl to Des Moines?

Delta and United Airlines are the most popular carriers operating from Syracuse Hancock Intl to Des Moines

When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Des Moines Airport?

Prices for flights from Syracuse Hancock Intl Airport to Des Moines Airport refresh daily.

How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Des Moines Airport?

As of August 2026, there are 3 operators available to choose from for flights from Syracuse Hancock Intl Airport to Des Moines Airport.

How old do you have to be to fly from Syracuse Hancock Intl Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$224 Cheap Flights from Syracuse to Des Moines in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Syracuse to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

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5:40 pm - 11:41 pmSYR Syracuse Hancock Intl-DSM Des Moines

7h 01m1 stop Washington, D.C. Reagan-National

6:00 am - 3:00 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 00m1 stop Philadelphia

$329American Airlines

Fri, Sep 25 - Sun, Sep 27

5:09 am - 12:46 pmSYR Syracuse Hancock Intl-DSM Des Moines

8h 37m1 stop Washington, D.C. Reagan-National

6:00 am - 11:26 amDSM Des Moines-SYR Syracuse Hancock Intl

4h 26m1 stop Washington, D.C. Reagan-National

$329American Airlines

Thu, Jan 7 - Mon, Jan 11

6:20 am - 9:38 amSYR Syracuse Hancock Intl-DSM Des Moines

4h 18m1 stop Detroit Metropolitan Wayne County

5:59 pm - 11:47 pmDSM Des Moines-SYR Syracuse Hancock Intl

4h 48m1 stop Minneapolis St Paul

$329Delta

Thu, Sep 17 - Sun, Sep 20

6:20 am - 9:38 amSYR Syracuse Hancock Intl-DSM Des Moines

4h 18m1 stop Detroit Metropolitan Wayne County

6:00 am - 12:55 pmDSM Des Moines-SYR Syracuse Hancock Intl

5h 55m1 stop Detroit Metropolitan Wayne County

$329Delta

Thu, Oct 1 - Sat, Oct 3

6:20 am - 9:38 amSYR Syracuse Hancock Intl-DSM Des Moines

4h 18m1 stop Detroit Metropolitan Wayne County

5:59 pm - 11:49 pmDSM Des Moines-SYR Syracuse Hancock Intl

4h 50m1 stop Minneapolis St Paul

$329Delta

Fri, Sep 25 - Sun, Sep 27

6:00 am - 2:11 pmSYR Syracuse Hancock Intl-DSM Des Moines

9h 11m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

1:45 pm - 11:23 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 38m1 stop Denver Intl

$334United Airlines

Thu, Jan 7 - Mon, Jan 11

6:10 am - 10:31 amSYR Syracuse Hancock Intl-DSM Des Moines

5h 21m1 stop Chicago O'Hare Intl

8:00 am - 7:08 pmDSM Des Moines-SYR Syracuse Hancock Intl

10h 08m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$334United Airlines

Thu, Oct 1 - Sat, Oct 3

12:06 pm - 7:09 pmSYR Syracuse Hancock Intl-DSM Des Moines

8h 03m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

2:01 pm - 11:40 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 39m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$339American Airlines

Thu, Jan 7 - Mon, Jan 11

9:50 pm - 2:36 pmSYR Syracuse Hancock Intl-DSM Des Moines

17h 46m1 stop Nashville Intl

7:30 am - 3:25 pmDSM Des Moines-SYR Syracuse Hancock Intl

6h 55m1 stop Nashville Intl

$363Allegiant Air

Thu, Nov 5 - Sun, Nov 8

10:18 am - 11:10 pmSYR Syracuse Hancock Intl-DSM Des Moines

13h 52m1 stop Fort Lauderdale

3:04 pm - 9:07 amDSM Des Moines-SYR Syracuse Hancock Intl

17h 03m1 stop Fort Myers SW Florida Intl

$448Multiple Airlines

Sun, Oct 18 - Fri, Oct 23

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Delta flights from Syracuse to Des Moines

Our best Delta deals on Syracuse to Des Moines flight tickets

Delta

Sep 25

SYR6:20 amSyracuse Hancock Intl

4h 18m

1 stop

DSM9:38 amDes Moines

Sep 27

DSM5:59 pmDes Moines

4h 50m

1 stop

SYR11:49 pmSyracuse Hancock Intl

$329

Delta

Sep 5

SYR6:00 amSyracuse Hancock Intl

6h 41m

1 stop

DSM11:41 amDes Moines

Sep 9

DSM4:20 pmDes Moines

6h 27m

1 stop

SYR11:47 pmSyracuse Hancock Intl

$377

Delta

Dec 28

SYR6:00 amSyracuse Hancock Intl

4h 24m

1 stop

DSM9:24 amDes Moines

Jan 2

DSM5:25 pmDes Moines

4h 33m

1 stop

SYR10:58 pmSyracuse Hancock Intl

$473

United Airlines flights from Syracuse to Des Moines

Our best United Airlines deals on Syracuse to Des Moines flight tickets

United Airlines

Oct 1

SYR6:10 amSyracuse Hancock Intl

5h 21m

1 stop

DSM10:31 amDes Moines

Oct 3

DSM8:00 amDes Moines

10h 08m

2 stops

SYR7:08 pmSyracuse Hancock Intl

$334

United Airlines

Sep 17

SYR6:10 amSyracuse Hancock Intl

5h 21m

1 stop

DSM10:31 amDes Moines

Sep 20

DSM6:24 amDes Moines

6h 50m

2 stops

SYR2:14 pmSyracuse Hancock Intl

$344

United Airlines

Sep 5

SYR5:48 pmSyracuse Hancock Intl

4h 35m

1 stop

DSM9:23 pmDes Moines

Sep 9

DSM5:45 amDes Moines

10h 07m

2 stops

SYR4:52 pmSyracuse Hancock Intl

$382

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Fri 9/25

5:40 pm-11:41 pm

1 stop7h 01m

Des Moines

Sun 9/27

6:00 am-3:00 pm

1 stop8h 00m

$329

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 1/7

5:09 am-12:46 pm

1 stop8h 37m

Des Moines

Mon 1/11

6:00 am-11:26 am

1 stop4h 26m

$329

Quickest round-trip

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 9/17

6:20 am-9:38 am

1 stop4h 18m

Des Moines

Sun 9/20

5:59 pm-11:47 pm

1 stop4h 48m

$329

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 10/1

6:20 am-9:38 am

1 stop4h 18m

Des Moines

Sat 10/3

6:00 am-12:55 pm

1 stop5h 55m

$329

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Fri 9/25

6:20 am-9:38 am

1 stop4h 18m

Des Moines

Sun 9/27

5:59 pm-11:49 pm

1 stop4h 50m

$329

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 1/7

6:00 am-2:11 pm

2 stops9h 11m

Des Moines

Mon 1/11

1:45 pm-11:23 pm

1 stop8h 38m

$334

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 10/1

6:10 am-10:31 am

1 stop5h 21m

Des Moines

Sat 10/3

8:00 am-7:08 pm

2 stops10h 08m

$334

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 1/7

12:06 pm-7:09 pm

2 stops8h 03m

Des Moines

Mon 1/11

2:01 pm-11:40 pm

2 stops8h 39m

$339

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Thu 11/5

9:50 pm-2:36 pm

1 stop17h 46m

Des Moines

Sun 11/8

7:30 am-3:25 pm

1 stop6h 55m

$363

SyracuseDes Moines

SYR Syracuse Hancock Intl - DSM Des Moines

SYRDSM

Syracuse Hancock Intl

Sun 10/18

10:18 am-11:10 pm

1 stop13h 52m

Des Moines

Fri 10/23

3:04 pm-9:07 am

1 stop17h 03m

$448

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Syracuse to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Syracuse and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $358 to $720.
The lowest price recently found on this route was $329.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then September is your next best option. Flight prices from Syracuse to Des Moines during September average around $328.

When to book flights from Syracuse to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Syracuse to Des Moines (SYR to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to Des Moines

Best Price Found	$224
Fastest flight time	4h 18m
Direct flights	None

The best one-way flight to Des Moines from Syracuse in the past 72 hours is $224. The best round-trip flight deal from Syracuse to Des Moines found on momondo in the last 72 hours is $329.

The fastest flight from Syracuse to Des Moines takes 4h 18m

There are no direct flights from Syracuse to Des Moines. There are no popular flight routes from Syracuse to Des Moines.

Search flight deals

Frequently asked questions about flying from Syracuse to Des Moines

How far is Syracuse Hancock Intl to Des Moines by plane?
Syracuse Hancock Intl and Des Moines are 896.5 mi apart from one another. Flights usually cover this in 4h 18m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Des Moines Airport?
Prices for flights from Syracuse Hancock Intl Airport to Des Moines Airport refresh daily.
How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Des Moines Airport?
As of August 2026, there are 3 operators available to choose from for flights from Syracuse Hancock Intl Airport to Des Moines Airport.
How old do you have to be to fly from Syracuse Hancock Intl Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Syracuse to Des Moines?
momondo data reveals that the most frequently booked airline on the route from Syracuse to Des Moines is Delta, representing 48% of all bookings. The subsequent popular airlines are United Airlines at 29% and American Airlines at 24%.

Best airlines flying from Syracuse to Des Moines

Compare and see reviews for airlines that fly from Syracuse to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $270	Free Cancellation	Rating 7.8 8,516 reviews	Search Delta flights
United Airlines	PriceFrom $305	Free Cancellation	Rating 7.4 10,110 reviews	Search United Airlines flights
American Airlines	PriceFrom $305	Free Cancellation	Rating 7.1 11,990 reviews	Search American Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Urbandale

Newton

Osceola

Johnston

Boone

Oskaloosa

Norwalk

Grinnell

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to Des Moines?

It is quick and easy to find Syracuse to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Syracuse to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Syracuse which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Syracuse to Des Moines?

Once you have performed a search for Syracuse to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Syracuse to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Syracuse are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Syracuse to Des Moines from $224

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to Des Moines departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from Syracuse to Des Moines

Our best Delta deals on Syracuse to Des Moines flight tickets

United Airlines flights from Syracuse to Des Moines

Our best United Airlines deals on Syracuse to Des Moines flight tickets

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How to get the cheapest flight ticket from Syracuse to Des Moines

What is the typical price of a round-trip flight between Syracuse and Des Moines?

What is the cheapest month to fly to Des Moines?

What is the cheapest airline that flies from Syracuse Hancock Intl to Des Moines?

What airlines fly to Des Moines?

When to book flights from Syracuse to Des Moines

Cheap Syracuse to Des Moines (SYR to DSM) flight deals and tips

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Frequently asked questions about flying from Syracuse to Des Moines

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Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

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