How many flights depart from St. Louis to Des Moines on average per week?

10 flights are operational weekly from St. Louis to Des Moines as of July 2025. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.

What is the cheapest airline that flies from Lambert-St Louis to Des Moines?

Southwest, American Airlines, and United Airlines are the most popular carriers operating from Lambert-St Louis to Des Moines

How many flights depart from St. Louis to Des Moines on average per day?

As of July 2025, there are 1 flights per day flying from St. Louis to Des Moines. The most common time of day flights depart is 10:00PM, with 44% of flights taking off at noon.

When did momondo last update prices for flights from Lambert-St Louis Airport to Des Moines Airport?

Prices for flights from Lambert-St Louis Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Lambert-St Louis Airport to Des Moines Airport?

As of July 2025, there is 1 operator available to choose from for flights from Lambert-St Louis Airport to Des Moines Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$49 Cheap Flights from St. Louis to Des Moines in 2025

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Find the cheapest flights from St. Louis to Des Moines

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

9:15 pm - 10:20 pmSTL-DSM

1h 05mnonstop

8:25 am - 9:30 amDSM-STL

1h 05mnonstop

$97Southwest

Find Deal

Wed, Aug 27 - Wed, Sep 3

10:15 am - 11:25 amSTL-DSM

1h 10mnonstop

6:30 am - 11:30 amDSM-STL

5h 00m1 stop

$107Southwest

Find Deal

Wed, Aug 27 - Wed, Sep 3

6:20 am - 2:40 pmSTL-DSM

8h 20m1 stop

6:30 am - 11:30 amDSM-STL

5h 00m1 stop

$122Southwest

Find Deal

Wed, Aug 27 - Wed, Sep 3

5:11 pm - 10:37 pmSTL-DSM

5h 26m1 stop

10:52 am - 3:55 pmDSM-STL

5h 03m1 stop

$167Delta

Find Deal

Sat, Sep 27 - Tue, Oct 7

6:01 am - 10:30 amSTL-DSM

4h 29m1 stop

6:39 pm - 11:41 pmDSM-STL

5h 02m1 stop

$172Delta

Find Deal

Tue, Sep 30 - Mon, Oct 6

7:55 pm - 1:40 pmSTL-DSM

17h 45m1 stop

2:25 pm - 9:07 amDSM-STL

18h 42m1 stop

$205Frontier

Find Deal

Sun, Sep 28 - Mon, Oct 6

9:20 am - 2:23 pmSTL-DSM

5h 03m1 stop

8:00 am - 2:27 pmDSM-STL

6h 27m1 stop

$260United Airlines

Find Deal

Fri, Sep 26 - Wed, Oct 8

5:28 pm - 9:50 pmSTL-DSM

4h 22m1 stop

6:30 am - 10:49 amDSM-STL

4h 19m1 stop

$266United Airlines

Find Deal

Fri, Sep 26 - Thu, Oct 9

8:03 pm - 11:28 pmSTL-DSM

3h 25m1 stop

5:42 pm - 11:05 pmDSM-STL

5h 23m1 stop

$294American Airlines

Find Deal

Sun, Sep 28 - Wed, Oct 8

7:23 am - 12:39 pmSTL-DSM

5h 16m1 stop

5:12 am - 11:50 amDSM-STL

6h 38m1 stop

$320American Airlines

Find Deal

Mon, Aug 25 - Mon, Sep 1

American Airlines flights from St. Louis to Des Moines

Our best American Airlines deals on St. Louis to Des Moines flight tickets

American Airlines

Sep 28

STL8:03 pmLambert-St Louis

3h 25m

1 stop

DSM11:28 pmDes Moines

Oct 8

DSM5:42 pmDes Moines

5h 23m

1 stop

STL11:05 pmLambert-St Louis

$294

Find similar

American Airlines

Aug 25

STL7:23 amLambert-St Louis

5h 16m

1 stop

DSM12:39 pmDes Moines

Sep 1

DSM5:12 amDes Moines

6h 38m

1 stop

STL11:50 amLambert-St Louis

$320

Find similar

American Airlines

Sep 28

STL8:03 pmLambert-St Louis

3h 25m

1 stop

DSM11:28 pmDes Moines

Oct 3

DSM5:38 pmDes Moines

5h 29m

1 stop

STL11:07 pmLambert-St Louis

$335

Find similar

Southwest flights from St. Louis to Des Moines

Our best Southwest deals on St. Louis to Des Moines flight tickets

Southwest

Aug 27

STL9:15 pmLambert-St Louis

1h 05m

DSM10:20 pmDes Moines

Sep 3

DSM8:25 amDes Moines

1h 05m

STL9:30 amLambert-St Louis

$97

Find similar

Southwest

Aug 27

STL10:15 amLambert-St Louis

1h 10m

DSM11:25 amDes Moines

Sep 3

DSM6:30 amDes Moines

5h 00m

1 stop

STL11:30 amLambert-St Louis

$107

Find similar

Southwest

Aug 27

STL6:20 amLambert-St Louis

8h 20m

1 stop

DSM2:40 pmDes Moines

Sep 3

DSM6:30 amDes Moines

5h 00m

1 stop

STL11:30 amLambert-St Louis

$122

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 8/27

9:15 pm-10:20 pm

Nonstop1h 05m

Des Moines

Wed 9/3

8:25 am-9:30 am

Nonstop1h 05m

$97

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 8/27

10:15 am-11:25 am

Nonstop1h 10m

Des Moines

Wed 9/3

6:30 am-11:30 am

1 stop5h 00m

$107

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 8/27

6:20 am-2:40 pm

1 stop8h 20m

Des Moines

Wed 9/3

6:30 am-11:30 am

1 stop5h 00m

$122

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 9/27

5:11 pm-10:37 pm

1 stop5h 26m

Des Moines

Tue 10/7

10:52 am-3:55 pm

1 stop5h 03m

$167

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 9/30

6:01 am-10:30 am

1 stop4h 29m

Des Moines

Mon 10/6

6:39 pm-11:41 pm

1 stop5h 02m

$172

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sun 9/28

7:55 pm-1:40 pm

1 stop17h 45m

Des Moines

Mon 10/6

2:25 pm-9:07 am

1 stop18h 42m

$205

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 9/26

9:20 am-2:23 pm

1 stop5h 03m

Des Moines

Wed 10/8

8:00 am-2:27 pm

1 stop6h 27m

$260

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 9/26

5:28 pm-9:50 pm

1 stop4h 22m

Des Moines

Thu 10/9

6:30 am-10:49 am

1 stop4h 19m

$266

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sun 9/28

8:03 pm-11:28 pm

1 stop3h 25m

Des Moines

Wed 10/8

5:42 pm-11:05 pm

1 stop5h 23m

$294

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 8/25

7:23 am-12:39 pm

1 stop5h 16m

Des Moines

Mon 9/1

5:12 am-11:50 am

1 stop6h 38m

$320

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in June, then December is your next best option. Flight prices from St. Louis to Des Moines during December average around $229.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from St. Louis to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $309. Flights from St. Louis to Des Moines on a Friday will generally be more expensive and average around $475. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from St. Louis to Des Moines in the afternoon for as low as $247. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $409. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Lambert-St Louis to Des Moines flight route?

Fly from Lambert-St Louis to Des Moines for the best Lambert-St Louis - Des Moines flight prices

What cabin class options are available on Lambert-St Louis to Des Moines flights?

There are 1 cabin classes available to choose from on Lambert-St Louis to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on St. Louis to Des Moines flights?

You could potentially save up to 1% on your flight if you consider stops on a St. Louis to Des Moines flight.

How have St. Louis to Des Moines flight prices changed over time?

As of July 2025, prices for St. Louis to Des Moines flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Des Moines (STL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Des Moines

Best Price Found	$49
Fastest flight time	1h 05m
Direct flights	Every day
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from St. Louis in the past 72 hours is $49. The best round-trip flight deal from St. Louis to Des Moines found on momondo in the last 72 hours is $97.

The fastest flight from St. Louis to Des Moines takes 1h 05m

Direct flights go from St. Louis to Des Moines every day.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Lambert-St Louis to Des Moines by plane?
A flight from Lambert-St Louis to Des Moines will travel around 273.0 mi. 1h 05m is a normal flight duration for this route.
When did momondo last update prices for flights from Lambert-St Louis Airport to Des Moines Airport?
Prices for flights from Lambert-St Louis Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Lambert-St Louis Airport to Des Moines Airport?
As of July 2025, there is 1 operator available to choose from for flights from Lambert-St Louis Airport to Des Moines Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from St. Louis to Des Moines?
momondo data reveals that the most frequently booked plane model on the route from St. Louis to Des Moines is Boeing 737 MAX 8, representing 23.81% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 23.81%, Airbus A320neo at 21.43%, and Boeing 737-700 Passenger/BBJ1 (winglets) at 16.67%.
What is the most popular airline from St. Louis to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from St. Louis to Des Moines is Southwest (100% of total bookings).

Best airlines flying from St. Louis to Des Moines

Compare and see reviews for airlines that fly from St. Louis to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $127	Free Cancellation	Rating 8.0 4,241 reviews		Search Southwest flights

Southwest Flights From St. Louis to Des Moines
Southwest operates around 10 flights from St. Louis to Des Moines every week. The average price of these flights found in the last 72 hours has been $310, but momondo users have found Southwest deals from St. Louis to Des Moines from as low as $127 round-trip. Southwest has been scored 8.0/10 in 4,241 reviews.

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Newton

Pella

Boone

Johnston

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Des Moines?

Finding the right flight to Des Moines from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from St. Louis to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for St. Louis to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from St. Louis to Des Moines?

Once you have performed a search for St. Louis to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Des Moines trip

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Cheap flights from St. Louis to Des Moines from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 10/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

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Filter for what you want

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Find the cheapest flights from St. Louis to Des Moines

Cheap round-trip flights

Cheap one-way flights

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Cheap direct flights

American Airlines flights from St. Louis to Des Moines

Our best American Airlines deals on St. Louis to Des Moines flight tickets

Southwest flights from St. Louis to Des Moines

Our best Southwest deals on St. Louis to Des Moines flight tickets

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Use the filters below to find and compare flights from St. Louis to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from St. Louis to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in June, then December is your next best option. Flight prices from St. Louis to Des Moines during December average around $229.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Lambert-St Louis to Des Moines flight route?

Fly from Lambert-St Louis to Des Moines for the best Lambert-St Louis - Des Moines flight prices

What cabin class options are available on Lambert-St Louis to Des Moines flights?

There are 1 cabin classes available to choose from on Lambert-St Louis to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on St. Louis to Des Moines flights?

You could potentially save up to 1% on your flight if you consider stops on a St. Louis to Des Moines flight.

How have St. Louis to Des Moines flight prices changed over time?

As of July 2025, prices for St. Louis to Des Moines flights are approximately 2% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Lambert-St Louis to Des Moines?

Southwest, American Airlines, and United Airlines are the most popular carriers operating from Lambert-St Louis to Des Moines

How many flights depart from St. Louis to Des Moines on average per day?

As of July 2025, there are 1 flights per day flying from St. Louis to Des Moines. The most common time of day flights depart is 10:00PM, with 44% of flights taking off at noon.

How many flights depart from St. Louis to Des Moines on average per week?

10 flights are operational weekly from St. Louis to Des Moines as of July 2025. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.

When to book flights from St. Louis to Des Moines

Cheap St. Louis to Des Moines (STL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

How far is Lambert-St Louis to Des Moines by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to Des Moines Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to Des Moines Airport?

How old do you have to be to fly from Lambert-St Louis Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular plane model from St. Louis to Des Moines?

What is the most popular airline from St. Louis to Des Moines?

Best airlines flying from St. Louis to Des Moines

Compare and see reviews for airlines that fly from St. Louis to Des Moines with momondo

Southwest Flights From St. Louis to Des Moines

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Des Moines?

Can I find flights from St. Louis to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to Des Moines?

I’m not ready to book a flight from St. Louis to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa